Autofagia
Los inhibidores de la autofagia se dirigen al proceso celular de la autofagia, que implica la degradación y el reciclaje de componentes celulares a través de lisosomas. La autofagia es un mecanismo crítico para mantener la homeostasis celular, pero su desregulación está implicada en diversas enfermedades, incluyendo el cáncer, la neurodegeneración y las infecciones. Los inhibidores de la autofagia pueden bloquear este proceso, lo que los convierte en herramientas valiosas para estudiar el papel de la autofagia en enfermedades y desarrollar estrategias terapéuticas. En CymitQuimica, ofrecemos inhibidores de la autofagia para apoyar su investigación en biología celular, oncología y enfermedades neurodegenerativas.
Se han encontrado 1489 productos de "Autofagia"
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G-quadruplex DNA fluorescence probe 1
<p>Compound E1 selectively targets G-quadruplex DNA, fluoresces, enters cells with low toxicity.</p>Fórmula:C27H31IN2O3Forma y color:SolidPeso molecular:558.45NA-Ir
CAS:NA-Ir is a ferroptosis (Ferroptosis) inducer that targets mitochondrial DNA (mtDNA) and activates the cGAS-STING pathway to stimulate ferritin autophagy (). It also induces the production of reactive oxygen species (ROS) through photodynamic therapy (PDT), depletes glutathione (GSH), and downregulates glutathione peroxidase 4 (GPX4), thereby triggering lipid peroxidation and ferroptosis. NA-Ir exhibits enhanced anticancer activity under light exposure and selectively inhibits cancer cells with high H2S content.Fórmula:C49H36F6IrN8O4PForma y color:SolidPeso molecular:1138.04Pantoprazole Sodium Hydrate
CAS:Pantoprazole Sodium Hydrate (BY1023 (sodium hydrate)) is a proton pump inhibitor drug, used for short-term treatment of erosion and ulceration of the esophagusFórmula:C16H14F2N3NaO4SH2OPureza:98.32%Forma y color:SolidPeso molecular:432.37Vimnerixin
CAS:Vimnerixin (AZD4721) is an orally administered CXCR2 antagonist for inflammation studies.Fórmula:C19H25FN4O5S2Forma y color:SolidPeso molecular:472.55PI3K-AKT-mTOR Compound Library
A unique collection of 420 compounds targeting PI3K/Akt/mTOR signaling for research in PI3K/Akt/mTOR signaling, and drug discovery in diseases involved withForma y color:Odour SolidRef: TM-L1300
1mgA consultar30μL*10mM (DMSO)A consultar50μL*10mM (DMSO)A consultar100μL*10mM (DMSO)A consultar250μL*10mM (DMSO)A consultarCyanine 5 Tyramide methyl indole
Cyanine 5 Tyramide is a red dye used in HRP assays and nucleic acid hybridization. Store away from light.Fórmula:C40H47N3O8S2Forma y color:SolidPeso molecular:761.95Clionamine B
CAS:Clionamine B, an aminosteroid from Cliona celata, enhances autophagy in MCF-7 breast cancer cells.Fórmula:C27H45NO3Forma y color:SolidPeso molecular:431.65Cy3-dCTP
Cy3-dCTP, a fluorescent cyanine-dye-labeled nucleotide triphosphate, serves as a DNA imaging probe.Fórmula:C43H51Li4N6O20P3S2Forma y color:SolidPeso molecular:1156.71MW-150 hydrochloride
CAS:MW-150 hydrochloride is a selective p38α MAPK inhibitor with a 101 nM Ki, offering good CNS penetration and oral bioavailability.Fórmula:C24H24ClN5Forma y color:SolidPeso molecular:417.93TC14012
CAS:CXCR4 antagonist and ACKR3 (CXCR7) agonist (EC50 = 350 nM for CXCR7).Fórmula:C90H140N34O19S2Pureza:98%Forma y color:SolidPeso molecular:2066.43TRAF6 peptide
CAS:TRAF6 peptide inhibits TRAF6-p62, blocks TrkA ubiquitination, and shows promise for neurological disease research.Fórmula:C145H238N34O44Forma y color:SolidPeso molecular:3161.64Levomepromazine
CAS:Levomepromazine (Methotrimeprazine) is a Ca2+ release inducer with antiviral, anti-inflammatory, neuroprotective, sedative, and anti-nociceptive activities.Fórmula:C19H24N2OSPureza:99.15%Forma y color:SolidPeso molecular:328.47ACT-1004-1239
CAS:<p>ACT-1004-1239 is a CXCR7 antagonist with immunomodulatory and myelination-promoting effects, used for research on inflammatory demyelinating diseases.</p>Fórmula:C27H28F2N6O3Pureza:98.31%Forma y color:SolidPeso molecular:522.55Motixafortide
CAS:Motixafortide (BKT140 4-fluorobenzoyl) is an antagonist of CXCR4 (IC50: 1 nM).Fórmula:C97H144FN33O19S2Pureza:98%Forma y color:SolidPeso molecular:2159.52CXCR2 antagonist 8
CAS:CXCR2 antagonist 8 is a selective CXCR2 antagonist, which can be used for the treatment and prevention of insulin resistance.Fórmula:C14H13N3O5Forma y color:SolidPeso molecular:303.27Rapalink-1
CAS:Rapalink-1 is an mTOR inhibitor that inhibits the mTORC1-4E-BP1 pathway in mice.Fórmula:C91H138N12O24Pureza:98%Forma y color:SolidPeso molecular:1784.14ATI-2341
CAS:ATI-2341, pepducin targeting the CXCR4, is an allosteric agonist activating the Gi to promote inhibition of cAMP production and induce calcium mobilization.Fórmula:C104H178N26O25S2Forma y color:SolidPeso molecular:2256.82Erlotinib-d6 hydrochloride
CAS:Erlotinib Hydrochloride inhibits purified EGFR kinase with an IC50 of 2 nM. Erlotinib D6 hydrochloride a deuterium labeled Erlotinib Hydrochloride.Fórmula:C22H24ClN3O4Pureza:98%Forma y color:SolidPeso molecular:435.93Ponatinib-d8
CAS:Ponatinib D8 is a deuterium-enriched, oral multi-kinase inhibitor (Abl, PDGFRα, VEGFR2, FGFR1, Src; IC50s: 0.37-5.4 nM).Fórmula:C29H27F3N6OPureza:98%Forma y color:SolidPeso molecular:540.61Ambroxol hydrochloride (Standard)
CAS:Ambroxol hydrochloride (Standard) is the standard substance of Ambroxol hydrochloride, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Ambroxol hydrochloride (Mucosolvan) is a metabolite of BROMHEXINE that stimulates mucociliary action and clears the air passages in the respiratory tract. It is usually administered as the hydrochloride.Fórmula:C13H18Br2N2O·HClPeso molecular:414.56
