Autofagia
Los inhibidores de la autofagia se dirigen al proceso celular de la autofagia, que implica la degradación y el reciclaje de componentes celulares a través de lisosomas. La autofagia es un mecanismo crítico para mantener la homeostasis celular, pero su desregulación está implicada en diversas enfermedades, incluyendo el cáncer, la neurodegeneración y las infecciones. Los inhibidores de la autofagia pueden bloquear este proceso, lo que los convierte en herramientas valiosas para estudiar el papel de la autofagia en enfermedades y desarrollar estrategias terapéuticas. En CymitQuimica, ofrecemos inhibidores de la autofagia para apoyar su investigación en biología celular, oncología y enfermedades neurodegenerativas.
Se han encontrado 1467 productos de "Autofagia"
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Pinosylvin
CAS:Pinosylvin (5-Styrylresorcinol) induces autophagy via AMPK activation. Pinosylvin is likely to act as a pro-angiogenic factor.Fórmula:C14H12O2Pureza:99.89% - 99.91%Forma y color:SolidPeso molecular:212.24U0126-EtOH
CAS:U0126-etoh (U0126 Ethanol) is a non-ATP competitive inhibitor of MEK1 (IC50=72 nM) and MEK2 (IC50=58 nM) with selectivity, inhibit autophagy. Low-Cost!Fórmula:C18H16N6S2·C2H6OPureza:99.72% - 99.88%Forma y color:SolidPeso molecular:426.6MW-150 dihydrochloride dihydrate
CAS:MW-150: selective CNS-penetrant p38α MAPK inhibitor, orally active, Ki 101 nM, blocks MK2 phosphorylation in glia.Fórmula:C24H29Cl2N5O2Forma y color:SolidPeso molecular:490.43Pinocembrin
CAS:Pinocembrin (5,7-Dihydroxyflavanone) is a flavanone, a type of flavonoid. It is an antioxidant found in damiana, honey, fingerroot, and propolis.Fórmula:C15H12O4Pureza:99.61% - >99.99%Forma y color:SolidPeso molecular:256.25IOWH-032
CAS:IOWH-032 (IOWH032) , a synthetic CFTR inhibitor, has been investigated for the treatment of cholera, diarrhea, and secretory diarrhea.Fórmula:C22H15Br2N3O4Pureza:98.92% - ≥95%Forma y color:SolidPeso molecular:545.18JMS-17-2 hydrochloride
CAS:JMS-17-2 hydrochloride: potent CX3CR1 blocker, IC50 of 0.32 nM, hinders breast cancer metastasis.Fórmula:C25H27Cl2N3OForma y color:SolidPeso molecular:456.41TBHQ
CAS:TBHQ (tert-Butylhydroquinone) is an antioxidant that induces an antioxidant response through the redox-sensitive transcription factor Nrf2.Fórmula:C10H14O2Pureza:99.17% - 99.53%Forma y color:White Solid PowderPeso molecular:166.22Ginsenoside F2
CAS:Ginsenoside F2 halts breast CSCs growth, induces apoptosis via intrinsic pathway and impairs mitochondria.Fórmula:C42H72O13Pureza:99.04% - 99.3%Forma y color:SolidPeso molecular:785.01Thiacloprid
CAS:Thiacloprid: insecticide targeting insect nAChRs, IC50 - Drosophila: 2.7 nM, Mouse α4β2 nAChRs: 860 nM.Fórmula:C10H9ClN4SPureza:98.66% - 99.95%Forma y color:Yellowish Crystalline PowderPeso molecular:252.72PFE-360
CAS:<p>PFE-360 (PF-06685360) is a potent and selective inhibitor of LRRK2 kinase (IC50: 2.3 nM in vivo).</p>Fórmula:C16H16N6OPureza:98.14% - 99.73%Forma y color:SolidPeso molecular:308.34Mocetinostat
CAS:Mocetinostat (MG0103) is an orally available HDAC inhibitor with most potency for HDAC1 (IC50: 0.15 μM), 2- to 10- fold selectivity against HDAC2/3/11.Fórmula:C23H20N6OPureza:99% - 99.21%Forma y color:SolidPeso molecular:396.44Sertaconazole
CAS:Sertaconazole is a broad-spectrum antifungal.Fórmula:C20H15Cl3N2OSPureza:99.483%Forma y color:SolidPeso molecular:437.77NAcM-OPT HCl(2089293-61-6 free base)
CAS:NAcM-OPT HCL: Oral DCN1 inhibitor targeting N-Acetyl-UBE2M & DCN1, IC50=79 nM.Fórmula:C23H30Cl3N3OPureza:99.43%Forma y color:SolidPeso molecular:470.86AZD-8055
CAS:<p>AZD8055 is an ATP-competitive mTOR inhibitor (IC50: 0.8 nM in MDA-MB-468 cells). It is ~1,000-fold selective for mTOR over all PI3K isoforms.</p>Fórmula:C25H31N5O4Pureza:98% - 99.69%Forma y color:SolidPeso molecular:465.54ARRY-797
CAS:<p>ARRY-797 (ARRY-371797) is a potent and selective p38α inhibitor and inhibits LPS-Induced IL-6.</p>Fórmula:C22H26F2N4O2Pureza:98.97% - 99.81%Forma y color:SolidPeso molecular:416.46Sulfosuccinimidyl oleate sodium
CAS:<p>Sulfosuccinimidyl oleate sodium is a long-chain fatty acid that inhibits fatty acid transport into cells.Cost-effective and quality-assured.</p>Fórmula:C22H36NNaO7SPureza:96.53%Forma y color:SolidPeso molecular:481.58Lamotrigine hydrate
CAS:Lamotrigine hydrate: oral anticonvulsant, blocks Na+ channels, stabilizes neurons, inhibits glutamate, treats epilepsy, focal seizure.Fórmula:C9H9Cl2N5OForma y color:SolidPeso molecular:274.11Entrectinib
CAS:Entrectinib (RXDX-101) is an orally Trk, ROS1, and ALK inhibitor. Entrectinib exhibits antitumor activity. Cost-effective and quality-assured.Fórmula:C31H34F2N6O2Pureza:98.03% - 99.61%Forma y color:SolidPeso molecular:560.64Quercetin
CAS:Quercetin (Sophoretin) is a natural flavonoid and is an agonist of SIRT1.Fórmula:C15H10O7Pureza:96.29% - 98.05%Forma y color:Sensitive To Exposure To Air And Light Insoluble In Water Alcoholic Solutions Taste Very Bitter (Ntp 1992)Peso molecular:302.24Dronedarone
CAS:<p>Dronedarone (SR 33589) is an amiodarone analogue which has an effective and promising treatment for Atrial fibrillation.</p>Fórmula:C31H44N2O5SPureza:98.85% - 99.58%Forma y color:SolidPeso molecular:556.76
