Autofagia
Los inhibidores de la autofagia se dirigen al proceso celular de la autofagia, que implica la degradación y el reciclaje de componentes celulares a través de lisosomas. La autofagia es un mecanismo crítico para mantener la homeostasis celular, pero su desregulación está implicada en diversas enfermedades, incluyendo el cáncer, la neurodegeneración y las infecciones. Los inhibidores de la autofagia pueden bloquear este proceso, lo que los convierte en herramientas valiosas para estudiar el papel de la autofagia en enfermedades y desarrollar estrategias terapéuticas. En CymitQuimica, ofrecemos inhibidores de la autofagia para apoyar su investigación en biología celular, oncología y enfermedades neurodegenerativas.
Se han encontrado 1483 productos de "Autofagia"
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Hemin
CAS:Hemin (Hemin chloride) is a chlorinated iron-containing porphyrin, a heme oxygenase (HO)-1 inducer.Fórmula:C34H32ClFeN4O4Pureza:97.169% - 99.59%Forma y color:Dark Purple Crystalline PowderPeso molecular:651.94β-Lapachone
CAS:β-Lapachone (ARQ-501) is a specific DNA topoisomerase I inhibitor, and no inhibitory activities against DNA topoisomerase II or ligase.Fórmula:C15H14O3Pureza:99.76% - 99.88%Forma y color:SolidPeso molecular:242.27DAPT
CAS:DAPT (LY-374973) is a γ-secretase inhibitor that inhibits total Aβ and Aβ42 (IC50=115/200 nM) and is orally active.Fórmula:C23H26F2N2O4Pureza:98.06% - 99.81%Forma y color:White SolidPeso molecular:432.46Ginsenoside Rb1
CAS:Ginsenoside Rb1 (Gypenoside Ⅲ) is part of a class of steroid glycosides; may have properties that inhibit or prevent the growth of tumors.Fórmula:C54H92O23Pureza:99.12% - 99.76%Forma y color:SolidPeso molecular:1109.29SB225002
CAS:SB225002 is a potent and selective CXCR2 antagonist inhibiting interleukin IL-8 binding to CXCR2.Fórmula:C13H10BrN3O4Pureza:98.16% - 99.85%Forma y color:SolidPeso molecular:352.14FC131 TFA (606968-52-9 free base)
CAS:FC131 TFA (606968-52-9 free base) (FC131 TFA) is an antagonist of CXCR4 that inhibits the binding of [125I] -sdf-1 to CXCR4(IC50 : 4.5 nM ), and has anti-hivFórmula:C38H48F3N11O8Pureza:99.39% - 99.67%Forma y color:SolidPeso molecular:843.85ATI-2341 acetate(1337878-62-2 free base)
ATI-2341 acetate is an effective allosteric agonist of CXCR4, it activates Gα1 instead of Gα13.Fórmula:C106H182N26O27S2Pureza:97.14%Forma y color:SolidPeso molecular:2316.87MSX-122
CAS:MSX-122 is a novel small molecule and partial CXCR4 antagonist, with potent inhibition of CXCR4/CXCL12 actions(IC50 = 10 nM).Fórmula:C16H16N6Pureza:98.31% - 98.94%Forma y color:SolidPeso molecular:292.34Acacetin
CAS:Acacetin (5,7-Dihydroxy-4'-methoxyflavone) is an O-methylated flavone found in various plants, shows antinociceptive, anti-inflammatory, and antioxidantFórmula:C16H12O5Pureza:96.26% - ≥95%Forma y color:Pale-Yellow NeedlesPeso molecular:284.26Danirixin
CAS:<p>Danirixin (GSK1325756) is a potent antagonist of CXCR2 that inhibits IL-8 binding to CXCR2 (IC50: 12.5 nM).</p>Fórmula:C19H21ClFN3O4SPureza:99.78% - >99.99%Forma y color:SolidPeso molecular:441.9Navarixin
CAS:Navarixin (MK-7123)(SCH527123) is a novel, selective CXC chemokine receptor 2(CXCR2) antagonist that inhibits neutrophil activation and modulates neutrophilFórmula:C21H23N3O5Pureza:98% - 99.51%Forma y color:SolidPeso molecular:397.42PD 169316
CAS:PD 169316 is a potent, cell-permeable and selective p38 MAP kinase inhibitor.Fórmula:C20H13FN4O2Pureza:98.65%Forma y color:SolidPeso molecular:360.34AMD 3465 hexahydrobromide
CAS:AMD 3465 hexahydrobromide (GENZ-644494 (hexahydrobromide)) is a CXCR4 receptor antagonist with potential anticancer and anti-HIV activity.Fórmula:C24H44Br6N6Pureza:99.39%Forma y color:SolidPeso molecular:896.07SB-265610
CAS:<p>SB-265610 (GSK-CXCR2) is a nonpeptide and allosteric CXCR2 antagonist.</p>Fórmula:C14H9BrN6OPureza:99.5%Forma y color:SolidPeso molecular:357.16ML339
CAS:<p>ML339 a selective inhibitor of CXCR6(IC50 = 140 nM) with no response when screened against CXCR5 and CXCR4.</p>Fórmula:C26H32ClN3O5Pureza:99.9%Forma y color:SolidPeso molecular:502AMD-070 hydrochloride
CAS:AMD-070 hydrochloride is a CXCR4 antagonist, is useful for Anti HIV.Fórmula:C21H28ClN5Pureza:98.38% - 98.57%Forma y color:SolidPeso molecular:385.93CTCE 9908 acetate
CTCE 9908 acetate is an antagonist of CXCR4 and inhibits migration in CXCR4-expressing ovarian cancer cells.Fórmula:C88H151N27O25Pureza:98.47%Forma y color:SolidPeso molecular:1987.31MSX-127
CAS:MSX-127 elicites positive response in peptide CXCR4.Fórmula:C16H24N2O4Pureza:98.43%Forma y color:SolidPeso molecular:308.37WZ811
CAS:<p>WZ811 is a novel and effective small molecular CXCR4 antagonist (EC50: 0.3 nM).</p>Fórmula:C18H18N4Pureza:99.42% - ≥95%Forma y color:SolidPeso molecular:290.36USL311
CAS:USL311 blocks CXCR4/SDF-1 interaction, inhibits tumor cell growth and migration.Fórmula:C24H34N6OPureza:98.46% - 99.56%Forma y color:SolidPeso molecular:422.57
