DUB

HBX 19818 is a specific ubiquitin-specific protease 7 (USP7) inhibitor (IC50: 28.1 μM).

IU1-47 is an effective and specific USP14 inhibitor (IC50: 0.6 μM). IU1-47 causes tau elimination …

MF-094 is a potent and selective inhibitor of USP30 with IC50 of 120 nM.

C527 is a is a pan DUB enzyme inhibitor. Which has a high potency for …

GRL0617 is a selective and competitive SARS-CoVPLpro and deubiquitinase noncovalent inhibitor(IC50 : 0.6 μM, Ki …

GSK2643943A is a deubiquitylating enzyme (DUB) inhibitor, with an IC 50 of 160 nM for …

Vialinin A (Terrestrin A) is a p-terphenyl compound with antioxidant properties [1]. Vialinin A is …

USP8-IN-2 is a potent inhibitor of the deubiquitinating enzymes USP7 and USP8, with an IC50 …

USP15-IN-1 is a potent USP15 inhibitor (IC50 is 3.76 μM). USP15-IN-1 showed high antiproliferative activity …

SJB3-019A is a potent, potent and novel ubiquitin-specific protease 1 (USP1) inhibitor, which promotes ID1 …

USP5-IN-1 (compound 64) is a potent deubiquitinase USP5 inhibitor, which binds to the USP5 ZnF-UBD …

USP8-IN-1 is an inhibitor of USP8 with an IC 50 of 1.9 μM. USP8-IN-1 inhibits …

USP8-IN-3 is a potent inhibitor of the deubiquitinating enzymes USP7 and USP8, with IC50 of …

P22077 is an inhibitor of ubiquitin-specific protease USP7 with EC50 of 8.6 μM. It also …

Thioguanine is an antineoplastic compound which also has antimetabolite action. The drug is used in …

GNE-6776 is a selective USP7 inhibitor.

IU1(IC50=4.7 μ M), a reversible, specific human USP14 proteasome inhibitor, can penetrate the cell.

P005091 is a selective and potent inhibitor of ubiquitin-specific protease 7 (USP7) with EC50 of …

VLX1570 is a competitive inhibitor of proteasome DUB activity with IC50 ranging from 4.2 uM …

LDN-57444 is a reversible, competitive proteasome Uch-L1 inhibitor(IC50=0.88 μM) .

ML323 is a reversible and effective USP1-UAF1 inhibitor in a Ub-Rho assay (IC50: 76 nM) …

IU1-248 is a derivative of IU1. IU1-248 is a potent and selective USP14 inhibitor with …

RA-9 is a potent and selective proteasome-associated inhibitor of deubiquitinating enzymes (DUBs), with favorable toxicity …

B-AP15(NSC687852) is a selective inhibitor of the deubiquitinating enzymes Usp14 and UCHL5 of the 26S …

PR-619 is a non-selective, reversible inhibitor of the deubiquitinylating enzymes (DUBs).

EOAI3402143 inhibits Usp9x and Usp24 activity, increases tumor cell apoptosis. EOAI3402143 phenocopies the FAS induction …

BAY 11-7082, a NF-κB inhibitor, inhibits TNFα-induced IκBα phosphorylation. BAY 11-7082 inhibits ubiquitin-specific protease USP7 …

Dub-in-2, with an IC50 value of 0.28 for USP8, is an effective deubiquitinase inhibitor.

Spautin-1 is a novel autophagy inhibitor, IM inhibited the growth of K562 cells with IC50 …

Benzamide, 4-[6-amino-4-ethyl-5-(4-hydroxyphenyl)-3-pyridinyl]-N-methyl- is a selective ubiquitin-specific protease 7 (USP7) inhibitor with an IC50 of 1.4 …

SJB2-043 is an inhibitor of USP1-UAF1 ( IC50 : 544 nM).

TCID(IC50=0.6 μM) is a DUB inhibitor of ubiquitin C-terminal hydrolase L3. It has the 125-fold …

NSC632839 is a nonselective isopeptidase inhibitor, which inhibits USP2 (EC50: 45±4 μM), USP7 (EC50: 37±1 …

DUB-IN-1, with an IC50 value of 0.24 for USP8, is an active inhibitor of ubiquitin-specific …

USP7/USP47 inhibitor is a selective ubiquitin-specific protease 7/47 (USP7/USP47) inhibitor, with EC50s of 0.42 μM …

Degrasyn (WP1130), a specific deubiquitinase (DUB: USP5, UCH-L1, USP9x, USP14, and UCH37) inhibitor, also inhibits …

USP7-IN-1 is a selective and reversible ubiquitin-specific protease 7 (USP7) inhibitor (IC50 = 77 μM).

N-ethylmaleimide is a sulfhydryl reagent that is widely used in experimental biochemical studies.

HBx 41108 is a non-competitive, reversible inhibitor of USP7 with an IC50 of 424nM. HBx …

XL177A is a selective irreversible USP7 inhibitor(IC50 : 0.34 nM). XL177A elicits cancer cell killing …

USP25/28 inhibitor AZ1 (AZ1) is an inhibitor of ubiquitin specific protease (USP) 25/28

GNE-6640 is a non-covalent inhibitor of ubiquitin epecific peptidase 7 (USP7), with IC50 values of …

LDN-91946 is an effective and selective inhibitor of ubiquitin C-terminal hydrolase-L1 (UCH-L1) (Ki = 2.8 …

USP30 inhibitor 18 is a selective inhibitor of USP30 (IC50 = 0.02 μM). USP30 inhibitor …

DUB-IN-3 is a potent deubiquitinase (USP) enzyme inhibitor extracted from reference compound 22c. The IC50 …

ML364 is an inhibitor of ubiquitin specific peptidase 2 (USP2) and can be used for …

FT671 is a non-covalent and selective inhibitor of USP7 (IC50: 52 nM) It also binds …

USP7-IN-3 is a potent and selective allosteric inhibitor of ubiquitin-specific protease 7 (USP7).

FT827 is a selective and covalent inhibitor of ubiquitin-specific protease 7 (USP7) (Ki: 4.2 μM). …

USP7-IN-6 is a potent inhibitor of ubiquitin-specific protease 7 (USP7, IC50: 6.8 nM).

USP7-IN-5 is a potent inhibitor of ubiquitin-specific protease 7 (USP7, IC50: 49.9 nM).