CaSR
El receptor sensible al calcio (CaSR) es un GPCR que juega un papel vital en el mantenimiento de la homeostasis del calcio al regular la secreción de la hormona paratiroidea y la reabsorción de calcio en los riñones. El CaSR también está involucrado en varios otros procesos fisiológicos, incluido el metabolismo óseo y la función vascular. Los moduladores de CaSR se utilizan en el tratamiento de afecciones como el hiperparatiroidismo, la osteoporosis y las enfermedades cardiovasculares. En CymitQuimica, ofrecemos una selección de moduladores de CaSR de alta calidad para apoyar su investigación en el metabolismo del calcio, endocrinología y salud ósea.
Se han encontrado 34 productos de "CaSR"
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Strontium ranelate
CAS:Strontium ranelate (S12911), a strontium (II) salt of the ranelic acid, is a medication for osteoporosis and can slow the course of osteoarthritis of the knee.Fórmula:C12H6N2O8S·2SrPureza:98.97%Forma y color:Crystalline SolidPeso molecular:513.49AC265347
CAS:AC265347 is a potent calcium-sensitive receptor (CaSR) agonist and ago-PAM orthosteric modulator with antitumour activity for the study of neuroblastoma.
Fórmula:C17H17NOSPureza:>99.99%Forma y color:SolidPeso molecular:283.39Evocalcet
CAS:Evocalcet (KHK7580) has an activating effect on the calcium-sensing receptor (CaSR).Fórmula:C24H26N2O2Pureza:98.88% - 99.68%Forma y color:SolidPeso molecular:374.48Etelcalcetide
CAS:Etelcalcetide (AMG 416), a synthetic peptide CaSR activator, treats secondary hyperparathyroidism in hemodialysis patients.Fórmula:C38H73N21O10S2Pureza:98%Forma y color:SolidPeso molecular:1048.26Poly-D-lysine hydrobromide (MW 1000-5000)
Poly-D-lysine hydrobromide (PDLHB) (MW 1000-5000) is a synthetically produced polymeric substrate widely used in neural cell culture. Additionally, Poly-D-lysine hydrobromide acts as a CaSR agonist peptide.Forma y color:Odour SolidPoly-D-lysine hydrobromide (MW 150000-300000)
Poly-D-lysine hydrobromide (MW 150000-300000) enhances neural cell adhesion in culture and acts as a calcium-sensing receptor agonist peptide in research.Forma y color:Odour SolidUpacicalcet HCl
Upacicalcet HCl, a calcium mimetic, reduces blood PTH by targeting parathyroid receptors; treats secondary hyperparathyroidism.Fórmula:C11H15Cl2N3O6SPureza:98.56%Forma y color:SoildPeso molecular:388.22γ-Glu-Abu TFA
Gamma-Glu-AbuTFA is the TFA salt form of Gamma-Glu-Abu. This compound acts as an agonist for the calcium sensing receptor (CaSR), activating CaSR in HEK-293 cells with an EC50 of 0.21 μM.Fórmula:C11H17F3N2O7Forma y color:SolidPeso molecular:346.26G-Glu-Val
CAS:G-Glu-Val (γ-glutamyl-L-valine, H-Glu-Val -OH), a flavour-regulating dipeptide, is a major contributor to "mellow".
Fórmula:C10H18N2O5Forma y color:SolidPeso molecular:246.26Calcium-Sensing Receptor Antagonists I
CAS:Calcium-Sensing Receptor Antagonists I functions as an antagonist to the parathyroid hormone receptors that sense calcium.Fórmula:C23H24N2O2Forma y color:SolidPeso molecular:360.45Cinacalcet
CAS:Cinacalcet (AMG 073) is an orally active, allosteric Ca receptor (CaR) agonist, treatment of cardiovascular disease .Fórmula:C22H22F3NPureza:99.48%Forma y color:Yellow OilPeso molecular:357.41NPS-2143 hydrochloride
CAS:NPS-2143 hydrochloride (NPS-2143 HCL) is a selective potent calcium ion-sensing receptor antagonist.Fórmula:C24H25ClN2O2·HClPureza:99.38% - 99.67%Forma y color:SolidPeso molecular:445.38Ref: TM-T4967
1mg43,00€2mg56,00€5mg87,00€10mg119,00€25mg203,00€50mg320,00€100mg475,00€1mL*10mM (DMSO)95,00€TNCA
CAS:TNCA (Lycoperodine-1) is a high-affinity CaSR ligand (CaSRL) with co-agonist activity.
Fórmula:C12H12N2O2Pureza:97.33% - 97.73%Forma y color:SolidPeso molecular:216.24Ligustroflavone
CAS:Ligustroflavone (Nuezhenoside) has anti-inflammatory activity.Fórmula:C33H40O18Pureza:98% - 99.92%Forma y color:SolidPeso molecular:724.66Gadolinium chloride
CAS:Gadolinium chloride is a calcium-sensing receptor (CaSR) agonistFórmula:Cl3GdPureza:98%Forma y color:White Crystalline SolidPeso molecular:263.61Cinacalcet hydrochloride
CAS:Cinacalcet hydrochloride (AMG-073 hydrochloride) is a naphthalene derivative and CALCIMIMETIC AGENT that increases the sensitivity of PARATHYROID GLAND calcium-Fórmula:C22H23ClF3NPureza:99.96% - >99.99%Forma y color:Off-White To Tan SolidPeso molecular:393.87Ref: TM-T2406
10mg50,00€25mg70,00€50mg88,00€100mg144,00€200mg185,00€500mg309,00€1mL*10mM (DMSO)52,00€Etelcalcetide hydrochloride
CAS:Etelcalcetide HCl, a synthetic peptide modulator of CaSR, lowers PTH in dialysis patients with secondary hyperparathyroidism.Fórmula:C38H73N21O10S2HClPureza:>99.99%Forma y color:SolidPeso molecular:1353.33NPS2390
CAS:NPS2390 is a first generation quinoxaline derivative that acts as a noncompetitive antagonist of mGluR1 and mGluR5 (IC50 of 5.2 and 82 nM, respectively)Fórmula:C19H21N3OPureza:97.13%Forma y color:SolidPeso molecular:307.39Ref: TM-T8457
5mg42,00€10mg64,00€25mg111,00€50mg187,00€100mg306,00€200mg423,00€1mL*10mM (DMSO)A consultarTecalcet Free Base
CAS:Tecalcet Free Base is an oral calcium receptor agonistFórmula:C18H22ClNOForma y color:SolidPeso molecular:303.83SB-423562 HCl
CAS:SB-423562 is a calcium-sensing receptor antagonist.Fórmula:C26H33ClN2O4Pureza:98%Forma y color:SolidPeso molecular:473
