CaSR
El receptor sensible al calcio (CaSR) es un GPCR que juega un papel vital en el mantenimiento de la homeostasis del calcio al regular la secreción de la hormona paratiroidea y la reabsorción de calcio en los riñones. El CaSR también está involucrado en varios otros procesos fisiológicos, incluido el metabolismo óseo y la función vascular. Los moduladores de CaSR se utilizan en el tratamiento de afecciones como el hiperparatiroidismo, la osteoporosis y las enfermedades cardiovasculares. En CymitQuimica, ofrecemos una selección de moduladores de CaSR de alta calidad para apoyar su investigación en el metabolismo del calcio, endocrinología y salud ósea.
Se han encontrado 31 productos para "CaSR".
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AC265347
CAS:AC265347 is a potent calcium-sensitive receptor (CaSR) agonist and ago-PAM orthosteric modulator with antitumour activity for the study of neuroblastoma.Fórmula:C17H17NOSPureza:>99.99%Forma y color:SolidPeso molecular:283.39Strontium ranelate
CAS:Strontium ranelate (S12911), a strontium (II) salt of the ranelic acid, is a medication for osteoporosis and can slow the course of osteoarthritis of the knee.Fórmula:C12H6N2O8S·2SrPureza:98.97%Forma y color:White SolidPeso molecular:513.49Evocalcet
CAS:Evocalcet (KHK7580) has an activating effect on the calcium-sensing receptor (CaSR).Fórmula:C24H26N2O2Pureza:98.88% - 99.68%Forma y color:SolidPeso molecular:374.48Upacicalcet HCl
Upacicalcet HCl, a calcium mimetic, reduces blood PTH by targeting parathyroid receptors; treats secondary hyperparathyroidism.Fórmula:C11H15Cl2N3O6SPureza:98.56%Forma y color:Yellow SolidPeso molecular:388.22Etelcalcetide
CAS:Etelcalcetide (AMG 416), a synthetic peptide CaSR activator, treats secondary hyperparathyroidism in hemodialysis patients.Fórmula:C38H73N21O10S2Pureza:98%Forma y color:SolidPeso molecular:1048.26γ-Glu-Abu TFA
Gamma-Glu-AbuTFA is the TFA salt form of Gamma-Glu-Abu. This compound acts as an agonist for the calcium sensing receptor (CaSR), activating CaSR in HEK-293 cells with an EC50 of 0.21 μM.Fórmula:C11H17F3N2O7Forma y color:SolidPeso molecular:346.26Calcium-Sensing Receptor Antagonists I
CAS:Calcium-Sensing Receptor Antagonists I functions as an antagonist to the parathyroid hormone receptors that sense calcium.Fórmula:C23H24N2O2Forma y color:SolidPeso molecular:360.45Cinacalcet
CAS:Cinacalcet (AMG 073) is an orally active, allosteric Ca receptor (CaR) agonist, treatment of cardiovascular disease .Fórmula:C22H22F3NPureza:99.48%Forma y color:Transparent LiquidPeso molecular:357.41NPS-2143 hydrochloride
CAS:NPS-2143 hydrochloride (NPS-2143 HCL) is a selective potent calcium ion-sensing receptor antagonist.Fórmula:C24H25ClN2O2·HClPureza:99.38% - 99.67%Forma y color:White SolidPeso molecular:445.38Ref: TM-T4967
1mg43,00€2mg56,00€5mg87,00€1mL*10mM (DMSO)95,00€10mg119,00€25mg203,00€50mg320,00€100mg475,00€TNCA
CAS:TNCA (Lycoperodine-1) is a high-affinity CaSR ligand (CaSRL) with co-agonist activity.Fórmula:C12H12N2O2Pureza:97.33% - 97.73%Forma y color:SolidPeso molecular:216.24Gadolinium chloride
CAS:Gadolinium chloride is a calcium-sensing receptor (CaSR) agonistFórmula:Cl3GdPureza:98%Forma y color:SolidPeso molecular:263.61Cinacalcet hydrochloride
CAS:Cinacalcet hydrochloride (AMG-073 hydrochloride) is a naphthalene derivative and CALCIMIMETIC AGENT that increases the sensitivity of PARATHYROID GLAND calcium-Fórmula:C22H23ClF3NPureza:99.96% - >99.99%Forma y color:SolidPeso molecular:393.87Ref: TM-T2406
1mL*10mM (DMSO)34,00€10mg48,00€25mg66,00€50mg84,00€100mg137,00€200mg175,00€500mg294,00€Etelcalcetide hydrochloride
CAS:Etelcalcetide HCl, a synthetic peptide modulator of CaSR, lowers PTH in dialysis patients with secondary hyperparathyroidism.Fórmula:C38H73N21O10S2·xHClPureza:>99.99%Forma y color:White SolidPeso molecular:1353.33NPS2390
CAS:NPS2390 is a first generation quinoxaline derivative that acts as a noncompetitive antagonist of mGluR1 and mGluR5 (IC50 of 5.2 and 82 nM, respectively)Fórmula:C19H21N3OPureza:97.13%Forma y color:SolidPeso molecular:307.39Tecalcet Free Base
CAS:Tecalcet Free Base is an oral calcium receptor agonistFórmula:C18H22ClNOForma y color:SolidPeso molecular:303.83SB-423562 HCl
CAS:SB-423562 is a calcium-sensing receptor antagonist.Fórmula:C26H33ClN2O4Pureza:98%Forma y color:SolidPeso molecular:473Ligustroflavone
CAS:Ligustroflavone (Nuezhenoside) has anti-inflammatory activity.Fórmula:C33H40O18Pureza:98% - 99.92%Forma y color:SolidPeso molecular:724.66Poly-D-lysine hydrobromide (MW 30000-70000)
CAS:Poly-D-lysine hydrobromide (MW 30000-70000) (Poly-D-lysine HBr) is a peptide CaSR agonist that removes proteinase K-resistant PrP from SN56 neuroblastoma cells.Fórmula:(C6H14N2O2)x·xHBrForma y color:Yellow ViscousPeso molecular:227.102NPS-2143
CAS:NPS-2143 (SB 262470A) is a novel potent and selective antagonist of Ca(2+) receptor.Fórmula:C24H25ClN2O2Pureza:99.56%Forma y color:SolidPeso molecular:408.92Calhex 231 hydrochloride
CAS:Calhex 231 hydrochloride a potent CaSR negative-conversion modulator that blocks the increase in [3H]inositol phosphate, inhibits mir-208a-mediated .Fórmula:C25H28Cl2N2OPureza:99.36%Forma y color:SolidPeso molecular:443.41
