Receptor de bombesina
Los receptores de bombesina son un grupo de GPCR que se activan por péptidos similares a la bombesina, los cuales están involucrados en la regulación de la función gastrointestinal, el equilibrio energético y la proliferación celular. Estos receptores son de particular interés en la investigación del cáncer, ya que a menudo están sobreexpresados en ciertos tipos de tumores. Los antagonistas de los receptores de bombesina se estudian por su potencial como terapias contra el cáncer. En CymitQuimica, ofrecemos una selección de moduladores de receptores de bombesina de alta calidad para apoyar su investigación en oncología, fisiología gastrointestinal y señalización de receptores.
Se han encontrado 35 productos de "Receptor de bombesina"
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CD80-IN-3
CAS:CD80-IN-3 is a potent CD80 inhibitor and inhibits CD80/CD28 interaction (Kd: 125 nM; EC50: 630 nM).Fórmula:C17H10FN3O3Pureza:98.08%Forma y color:SolidPeso molecular:323.28Ref: TM-T10722
1mg80,00€5mg187,00€10mg305,00€25mg494,00€50mg682,00€100mg847,00€1mL*10mM (DMSO)207,00€Ici 216140
CAS:ICI 216140: GRP/bombesin receptor 2 blocker, potent at 2 nM. Reduces amylase at 2 mg/kg and lowers bombesin-induced blood pressure at 1 mM in rats.Fórmula:C45H65N13O8Forma y color:SolidPeso molecular:916.08AMTG-DA1
AMTG-DA1 is a ligand for the gastrin-releasing peptide receptor (GRPR), and it can be utilized in cancer research.Fórmula:C101H149IN22O25Forma y color:SolidPeso molecular:2197.0109RC-3095
CAS:RC-3095, a selective GRPR antagonist, has been shown to have anti-inflammatory properties in different models of inflammation.Fórmula:C56H79N15O9Pureza:98%Forma y color:SolidPeso molecular:1106.32BA 1
CAS:Potent BB1, BB2, and BB3 agonist; IC50: 0.26, 1.55, 2.52 nM. Boosts glucose transport in myocytes, promotes cancer cell growth in vitro.Fórmula:C57H76N14O11Pureza:98%Forma y color:SolidPeso molecular:1133.32PSMA/GRPR ligand 1
PSMA/GRPR ligand 1 (compound 3) is a bispecific ligand with dual targeting capabilities for tumors that express PSMA(+) and GRPR(+).Forma y color:Odour Solid[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P
CAS:Broad-spectrum inverse agonist; potent at ghrelin receptor (EC50=5.2 nM); blocks other neuropeptide receptors; induces apoptosis; inhibits tumor growth.Fórmula:C79H109N19O12Pureza:98%Forma y color:SolidPeso molecular:1516.85[D-Phe12]-Bombesin
CAS:<p>Bombesin receptor antagonist</p>Fórmula:C74H112N22O18SPureza:98%Forma y color:SolidPeso molecular:1629.88RC-3095 TFA
CAS:RC-3095 TFA (RC-3095 (TFA)) is a bombesin/gastrin-releasing peptide (BN/GRP) antagonist with potential anticancer activity.Fórmula:C58H80F3N15O11Pureza:98%Forma y color:SolidPeso molecular:1220.34[D-Phe12,Leu14]-Bombesin
CAS:Bombesin receptor blocker; stops binding in rat brain (IC50=2 μM), hinders amylase release (IC50=4 μM), reduces appetite suppression in vivo.Fórmula:C77H113F3N22O20Pureza:98%Forma y color:SolidPeso molecular:1724.9GB-6
CAS:GB-6, a short linear peptide that selectively binds to the gastrin releasing peptide receptor (GRPR), shows potential as a high-contrast imaging probe due toFórmula:C32H45N11O8Pureza:98%Forma y color:SolidPeso molecular:711.77GRP (14-27) (human, porcine, canine)
CAS:<p>GRP (14-27) (human, porcine, canine) functions as a ligand for bombesin receptors, with its specific binding being inhibited by GTP and GDP, while GMP does not</p>Fórmula:C75H110N24O16S2Pureza:98%Forma y color:SolidPeso molecular:1667.96Gastrin-Releasing Peptide, human
CAS:Gastrin-releasing peptide, released by vagal fibers, stimulates stomach G cells to secrete gastrin, affecting acid secretion and gut motility.Fórmula:C130H204N38O31S2Pureza:98%Forma y color:SolidPeso molecular:2859.38(D-Phe6,Leu-NHEt13,des-Met14)-Bombesin (6-14)
CAS:<p>(D-Phe6,Leu-NHEt13,des-Met14)-Bombesin (6-14), a bombesin (BBN) antagonist, holds potential for cancer research applications [1].</p>Fórmula:C49H69N13O9Forma y color:SolidPeso molecular:984.15BA 1 TFA
BA1 TFA agonizes BB receptors; binds BRS3, GRPR, NMBR with IC50s of 6, 0.4, 2.5 nM.Fórmula:C59H77F3N14O13Forma y color:SolidPeso molecular:1247.32Biotin-Gastrin Releasing Peptide, human TFA
Biotin-Gastrin Releasing Peptide, human TFA, is a biotinylated form of the gastrin-releasing peptide (GRP). GRP is a neuropeptide known for its growth-stimulating and tumorigenic properties.Forma y color:Odour SolidNOTA-P2-RM26
CAS:NOTA-P2-RM26 is a high-affinity NOTA-conjugated bombesin antagonist designed for GRPR-targeted tumor imaging.Fórmula:C73H110N18O19Peso molecular:1543.76PD176252
CAS:PD176252 is a BB1 and BB2 antagonist, GRPR inhibitor, and FPR1/FPR2 agonist that inhibits the growth and proliferation of a wide range of cancer cells.Fórmula:C32H36N6O5Pureza:99.00%Forma y color:SolidPeso molecular:584.67Bombesin
CAS:Bombesin: 14-amino acid peptide from toad skin with two mammalian homologs, neuromedin B and gastrin-releasing peptide.Fórmula:C71H110N24O18SForma y color:While Lyophilized PowderPeso molecular:1619.85ML-18
CAS:ML-18 is a non-peptide bombesin receptor subtype-3 (BRS-3) antagonist with an IC50 of 4.8 μM.Fórmula:C32H35N5O5Pureza:98.62% - >99.99%Forma y color:SolidPeso molecular:569.65Ref: TM-T4540
1mg35,00€5mg64,00€10mg92,00€25mg178,00€50mg279,00€100mg449,00€200mg620,00€1mL*10mM (DMSO)80,00€Litorin acetate(55749-97-8 Free base)
Litorin acetate, an amphibian bombesin peptide derivative, is an bombesin receptor agonist.Fórmula:C53H72N14O13SPureza:98.61%Forma y color:SolidPeso molecular:1145.29Kuwanon H
CAS:Kuwanon H is a potent non-peptide GRP receptor antagonist with a Ki of 290 nM, useful in GRP-related studies.Fórmula:C45H44O11Pureza:97.09% - 97.99%Forma y color:SolidPeso molecular:760.82Bombesin acetate(31362-50-2 free base)
CAS:<p>Bombesin acetate is a 14-amino acid peptide originally isolated from the skin of the European fire-bellied toad (Bombina bombina).</p>Fórmula:C73H114N24O20SPureza:98.44%Forma y color:SolidPeso molecular:1679.92BA 1 acetate(183241-31-8 free base)
BA 1 acetate: bombesin agonist, IC50s: 0.26/1.55/2.52 nM (BB1/BB2/BB3), boosts glucose transport, promotes lung cancer cell growth in vitro.Fórmula:C59H80N14O13Pureza:95.3%Forma y color:SolidPeso molecular:1193.35[D-Phe12,Leu14]-Bombesin acetate
[D-Phe12,Leu14]-Bombesin acetate inhibits bombesin-stimulated secretion.Fórmula:C77H118N22O20Pureza:98.41% - 99.14%Forma y color:SolidPeso molecular:1671.9[D-Phe12]-Bombesin acetate
[D-Phe12]-Bombesin acetate inhibits bombesin-stimulated secretion.Fórmula:C76H116N22O20SPureza:99.81%Forma y color:SolidPeso molecular:1689.94kuwanon G
CAS:Kuwanon G (Moracenin B) may be used to treat the type II diabetes mellitus as a dual inhibitor of PTP1B and α-glucosidase and as an insulin sensitiser.Fórmula:C40H36O11Pureza:98% - 99.57%Forma y color:SolidPeso molecular:692.71Ref: TM-T3S1612
1mg66,00€5mg145,00€10mg210,00€25mg339,00€50mg492,00€100mg662,00€200mg892,00€1mL*10mM (DMSO)188,00€Litorin
CAS:Litorin suppresses appetite and stimulates smooth muscle, gastrin, gastric acid, and pancreatic secretion.Fórmula:C51H68N14O11SForma y color:White PowderPeso molecular:1085.24MK-5046
CAS:MK-5046 is a novel BRS-3 agonist, binding to BRS-3 with high affinity (mouse Ki = 1.6 nM, human Ki = 25 nM).Fórmula:C20H18F6N4OPureza:98.56%Forma y color:SolidPeso molecular:444.37DSO-5a
CAS:DSO-5a, a potent and selective orally active BB3 agonist, is a DMAKO-00 derivative that enhances ppar-γ activity via BB3 and stimulates ERK1/2 phosphorylation.Fórmula:C23H24N2O7Pureza:98%Forma y color:SolidPeso molecular:440.45Bag-1
CAS:Bag-1 is a novel potent, non-peptidic bombesin receptor subtype-3 (BRS-3) agonist.Fórmula:C22H27N3Forma y color:SolidPeso molecular:333.47PD 168368
CAS:PD 168368 is a mixed neuromodulin B receptor (NMB-R) antagonist and potent FPR1/FPR2/FPR3 agonist that inhibits the gastrin-releasing peptide receptor.Fórmula:C31H34N6O4Pureza:98.11% - 99.87%Forma y color:SolidPeso molecular:554.64Ref: TM-T8691
1mg88,00€5mg170,00€10mgA consultar25mg518,00€50mgA consultar100mgA consultar1mL*10mM (DMSO)A consultarPD 165929
CAS:PD 165929 is a selective antagonist of Bombesin BB1.Fórmula:C37H47N5O2Pureza:98%Forma y color:SolidPeso molecular:593.8GRPR antagonist-1
GRPR antagonist-1 targets GRPR, kills specific cancer cells (e.g., PC3, Pan02, HGC-27), and promotes apoptosis by modulating Bcl-2 and Bax.Fórmula:C29H33F3N4O4Forma y color:SolidPeso molecular:558.59GRPR antagonist-2
GRPR antagonist-2 blocks GRPR, kills some cancer cells, effective on HGC-27 (IC50: 0.77 μM) & Pan02 (IC50: 2.5 μM).Fórmula:C28H32F3N5O4Forma y color:SolidPeso molecular:559.58
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