Receptor de histamina
Los receptores de histamina son GPCR que median los efectos de la histamina, una amina biógena involucrada en las respuestas inmunitarias, la secreción de ácido gástrico y la neurotransmisión. Hay cuatro subtipos de receptores de histamina (H1, H2, H3 y H4), cada uno de los cuales desempeña roles distintos en las reacciones alérgicas, la función gástrica y la actividad del sistema nervioso central. Los antagonistas de los receptores de histamina se utilizan ampliamente en el tratamiento de alergias, úlceras pépticas y mareos por movimiento. En CymitQuimica, ofrecemos una selección integral de moduladores de receptores de histamina de alta calidad para apoyar su investigación en inmunología, gastroenterología y neurofarmacología.
Se han encontrado 385 productos de "Receptor de histamina"
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Mizolastine dihydrochloride
CAS:Mizolastine dihydrochloride is a histamine H1-receptor antagonist (IC50: 47 nM).Fórmula:C24H27Cl2FN6OPureza:98%Forma y color:SolidPeso molecular:505.42Phenyltoloxamine
CAS:Phenyltoloxamine (Bistrimin): antihistamine with sedative, analgesic properties, and Sigma-1 receptor affinity (Ki=160 nM).Fórmula:C17H21NOForma y color:SolidPeso molecular:255.35GSK334429
CAS:GSK334429 is an antagonist of histamine H3 receptor.Fórmula:C20H29F3N4OForma y color:SolidPeso molecular:398.47Sequifenadine
CAS:Sequifenadine has the potential in researching of inflammatory eye disease with allergic symptoms that is a H1-antihistamine [1] [2].Fórmula:C22H27NOForma y color:SolidPeso molecular:321.46A-940894
CAS:A-940894: Potent H4 receptor antagonist, anti-inflammatory, binds well to human/rat H4, low affinity for H1/H2/H3, good pharmacokinetics.Fórmula:C17H21N5Forma y color:SolidPeso molecular:295.38Immepip
CAS:Immepip, a H3 agonist, has been shown to attenuate cortical histamine release and is utilized in the research of neurological diseases.Fórmula:C9H15N3Forma y color:SolidPeso molecular:165.24Repirinast
CAS:Repirinast is a mediator release inhibitor. It is used to treat asthma.Fórmula:C20H21NO5Forma y color:SolidPeso molecular:355.38N-Acetylhistamine
CAS:N-Acetylhistamine (N-Omega-acetylhistamine) is a metabolite of histamine.Fórmula:C7H11N3OPureza:99.51%Forma y color:SolidPeso molecular:153.18Izuforant
CAS:Izuforant (JW1601) has anti-inflammatory effects, binds h5-HT3R (IC50: 9.1 μM), and blocks H4R orally (IC50: 36 nM).Fórmula:C12H12BrN7Forma y color:SolidPeso molecular:334.17A-943931
CAS:A-943931 is a selective histamine H4 receptor antagonist with human and rat Ki values of 4.6 and 3.8 nM respectively.inhibits the scratching response in mice.Fórmula:C17H21N5Pureza:99.79%Forma y color:SolidPeso molecular:295.38Pitolisant oxalate
CAS:Pitolisant oxalate is a potent and selective inverse agonist of nonimidazole at the recombinant human histamine H3 receptor with Ki of 0.16 nM.Fórmula:C19H28ClNO5Pureza:98%Forma y color:SolidPeso molecular:385.88PF-03654746
CAS:PF-03654746: selective H3 antagonist, boosts cognition in Alzheimer's, may treat allergic rhinitis.Fórmula:C18H24F2N2OPureza:98.85% - 99.57%Forma y color:SolidPeso molecular:322.39AZD5213
CAS:AZD5213: selective human H3 receptor antagonist, pKi 9.3, for sleep/cognition research.Fórmula:C19H25N3O2Forma y color:SolidPeso molecular:327.42Pirolate
CAS:Pirolate is a receptor of histamine H1.Fórmula:C16H15N3O5Pureza:98%Forma y color:SolidPeso molecular:329.31Bepotastine tosylate
CAS:Bepotastine tosylate: Oral 2nd-gen H1 antagonist, inhibits histamine effects on NGF; treats conjunctivitis, urticaria.Fórmula:C28H33ClN2O6SForma y color:SolidPeso molecular:561.09VUF-10497
CAS:VUF-10497: H4 receptor inverse agonist, anti-inflammatory in rats, binds human H1 receptor (pKi=7.57).Fórmula:C18H20ClN5SPureza:98%Forma y color:SolidPeso molecular:373.9Phenindamine
CAS:Phenindamine (Nu 1504) is an H1-receptor antagonist which is antihistamine[1].Fórmula:C19H19NForma y color:SolidPeso molecular:261.36Acreozast
CAS:Acreozast, a histamine release inhibitor, is used potentially for the treatment of asthma and atopic dermatitis.Fórmula:C15H14ClN3O6Forma y color:SolidPeso molecular:367.74CP19
CAS:CP19 blocks histamine receptors; inhibits EBOV and MARV with IC50s of 3.4 μM and 29.5 μM, respectively; antiviral [1].Fórmula:C26H30N2O5Forma y color:SolidPeso molecular:450.53Phenindamine Tartrate
CAS:Phenindamine Tartrate, an antihistamine and anticholinergic, treats colds and allergies like sneezing and rashes.Fórmula:C23H25NO6Forma y color:SolidPeso molecular:411.454
