Receptor de opioides
Los receptores opioides son un grupo de receptores acoplados a proteínas G que median los efectos de los opioides endógenos y exógenos. Estos receptores desempeñan un papel central en la modulación del dolor, la regulación del estado de ánimo y los comportamientos adictivos. Los agonistas y antagonistas de los receptores opioides se utilizan ampliamente en el manejo del dolor y el tratamiento de adicciones, así como en la investigación de trastornos neurológicos y psiquiátricos. En CymitQuimica, ofrecemos una selección integral de moduladores de receptores opioides de alta calidad para apoyar su investigación en neurobiología, manejo del dolor y terapia de adicciones.
Se han encontrado 326 productos de "Receptor de opioides"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Boc-ypgflt(O-tbu)
CAS:Boc-ypgflt(O-tbu) is a delta-receptor-selective opioid antagonist.Fórmula:C44H64N6O11Forma y color:SolidPeso molecular:853.01[DPro10] Dynorphin A (1-11)acetate,porcine
[DPro10] Dynorphin A (1-11)acetate,porcine is a highly potent κ-opioid receptor agonist with a Ki value of 0.13 nM.Fórmula:C65H107N21O15Pureza:99.59%Forma y color:SoildPeso molecular:1422.7Neurotransmitter Receptor Compound Library
<p>A unique collection of 1513 neurotransmitter receptor compounds, can be used for HTS and HCS screening；</p>Forma y color:Odour SolidOrphanin FQ(1-11)
CAS:<p>Nociceptin peptide fragment (1-11) with potent ORL1/KOR-3 receptor agonism (Ki = 55 nM), no opioid receptor affinity, and analgesic in mice.</p>Fórmula:C49H75N15O14Pureza:98%Forma y color:SolidPeso molecular:1098.2[Arg14,Lys15]Nociceptin
CAS:Potent NOP agonist (EC50 = 1 nM), >875x selective vs opioid receptors; outperforms nociceptin in vivo, increases pain perception, reduces movement.Fórmula:C82H137N31O22Pureza:98%Forma y color:SolidPeso molecular:1909.18Axelopran
CAS:<p>Axelopran (TD-1211) treats opioid constipation; it's a potent, selective peripheral opioid blocker.</p>Fórmula:C26H39N3O4Forma y color:SolidPeso molecular:457.61ICI 174,864
CAS:<p>Selective δ opioid antagonist. Exhibits partial agonist in vitro activity at δ receptors at high concentrations.</p>Fórmula:C38H53N5O7Pureza:98%Forma y color:White SolidPeso molecular:691.87DAMGO (TFA)
CAS:DAMGO is a selective peptide agonist of the µ-opioid receptor .Fórmula:C28H36F3N5O8Pureza:98%Forma y color:SolidPeso molecular:627.61KOR agonist 5
KOR agonist 5 (Compound 10a) is both a KOR/MOR modulator, exhibiting agonistic effects on KOR and antagonistic effects on MOR. It effectively blocks morphine-induced antinociception and gastrointestinal motility inhibition. KOR agonist 5 is applicable in research related to substance use disorder (SUD).Fórmula:C38H38N2O5Forma y color:SolidPeso molecular:602.72[Nphe1]Nociceptin(1-13)NH2
CAS:<p>Competitive nociceptin receptor antagonist with pKi=8.4; no agonist activity; blocks nociceptin effects in vitro/in vivo.</p>Fórmula:C61H100N22O15Pureza:98%Forma y color:SolidPeso molecular:1381.6UFP-101
CAS:<p>Strong, selective NOP receptor antagonist with pKi=10.24; >3000x selectivity over δ, μ, κ receptors; blocks nociceptin effects.</p>Fórmula:C82H138N32O21Pureza:98%Forma y color:SolidPeso molecular:1908.19HINT1-IN-1
HINT1-IN-1 (compound 8) is an inhibitor of histidine triad nucleotide-binding protein 1 (HINT1) with a Ki of 1.14 μM. It influences the cross-regulation between μ-opioid receptors (MOR) and NMDA receptors (NMDAR).Fórmula:C23H24N8O5Forma y color:SolidPeso molecular:492.49KOR agonist 4
<p>KOR agonist 4 (compound 39) is an agonist targeting the κ opioid receptor (Kappa Opioid Receptor) and activates G protein signaling. It has an EC50 of 14 nM and an Emax of 83% for binding to GTPγS. This compound demonstrates moderate to high intrinsic clearance in human liver cells and shows selectivity for the κ opioid receptor over the μ (MOR) and δ (DOR) opioid receptors by factors of 60 and 810, respectively. KOR agonist 4 is useful for research into central nervous system (CNS) disorders.</p>Fórmula:C21H25N3Forma y color:SolidPeso molecular:319.44β-Endorphin, equine TFA
β-Endorphin, equine TFA, an endogenous opioid peptide, demonstrates high affinity binding to μ/δ opioid receptors and possesses analgesic properties [1] [2] [3Fórmula:C156H249F3N42O46SForma y color:SolidPeso molecular:3537.96Akuammicine
CAS:Akuammicine, as an indole alkaloid from Catharanthus roseus, can be used in cancer cell eradication.Fórmula:C20H22N2O2Forma y color:SolidPeso molecular:322.408Nociceptin(1-7)
CAS:Bioactive metabolite of nociceptin, antagonist of nociceptin-induced hyperalgesiaFórmula:C31H41N7O9Pureza:98%Forma y color:SolidPeso molecular:655.709[(pF)Phe4]Nociceptin(1-13)NH2
CAS:<p>Potent, selective OP4 agonist; pKi=10.68, pEC50=9.80. >8000x selectivity vs other opioid receptors; long-lasting in vivo effects.</p>Fórmula:C61H99FN22O15Pureza:98%Forma y color:SolidPeso molecular:1399.6Dermorphin Analog
Dermorphin Analog, a heptapeptide from amphibian skin, binds μ-opioid receptors selectively and strongly.Fórmula:C44H59N11O10Pureza:98%Forma y color:SolidPeso molecular:901.43β-Naltrexamine dihydrochloride
CAS:β-Naltrexamine dihydrochloride is an orally administered, irreversible opioid receptor antagonist. Its derivatives exhibit optimised subtype selectivity and can be used for pain research.Fórmula:C20H28Cl2N2O3Pureza:95.98%Forma y color:SoildPeso molecular:415.35PL-017
CAS:μ opioid receptor agonist; IC50: 5.5 nM (μ), >10,000 nM (δ). Induces reversible analgesia, catalepsy, hyperthermia in rats.Fórmula:C29H37N5O5Pureza:98%Forma y color:SolidPeso molecular:535.64
![[DPro10] Dynorphin A (1-11)acetate,porcine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FT76341L.webp&w=3840&q=75)
![[Arg14,Lys15]Nociceptin](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FTP1986.webp&w=3840&q=75)
![[Nphe1]Nociceptin(1-13)NH2](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FTP1987.webp&w=3840&q=75)
![[(pF)Phe4]Nociceptin(1-13)NH2](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FTP1885.webp&w=3840&q=75)
