Receptor de dopamina
Los receptores de dopamina son un grupo de receptores acoplados a proteínas G (GPCR) que responden al neurotransmisor dopamina, jugando un papel clave en la regulación del movimiento, la motivación, la recompensa y varias funciones cognitivas. Estos receptores se dividen en familias similares a D1 y D2, cada una con funciones y perfiles farmacológicos distintos. Los moduladores de los receptores de dopamina se estudian ampliamente por sus aplicaciones en el tratamiento de la enfermedad de Parkinson, la esquizofrenia, la adicción y otros trastornos neuropsiquiátricos. En CymitQuimica, ofrecemos una amplia gama de moduladores de receptores de dopamina de alta calidad para apoyar su investigación en neurociencia, salud mental y señalización GPCR.
Se han encontrado 407 productos de "Receptor de dopamina"
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SKF 81297 hydrobromide
CAS:<p>SKF 81297 hydrobromide, a selective agonist of the dopamine D1-like receptor，exhibits central activity and is widely used to study the neuromodulatory effects.</p>Fórmula:C16H17BrClNO2Pureza:99.52%Forma y color:SolidPeso molecular:370.67CP-293019
CAS:<p>CP-293019 is a potent, selective antagonist of dopamine D4 receptor.</p>Fórmula:C19H22F2N4OPureza:98%Forma y color:SolidPeso molecular:360.44-Amino-PPHT Hydrobromide
CAS:<p>4-Amino-PPHT Hydrobromide is a precursor for fluorescent labeled Dopamine D2 receptors agonist.</p>Fórmula:C21H28N2OPureza:98%Forma y color:SolidPeso molecular:324.46PAOPA
CAS:<p>dopamine D2 receptor modulator</p>Fórmula:C11H18N4O3Pureza:>99.99%Forma y color:SolidPeso molecular:254.29NMI 8739
CAS:<p>NMI 8739 (n-docosahexaenoyl dopamine) is an agonist of D2 autoreceptor.</p>Fórmula:C30H41NO3Pureza:98.51%Forma y color:SolidPeso molecular:463.65Lumateperone
CAS:<p>Lumateperone (ITI 722) is a 5HT2A receptor antagonist and a dopamine receptor phosphoprotein modulator (DPPM).</p>Fórmula:C24H28FN3OPureza:99.68% - 99.91%Forma y color:SolidPeso molecular:393.5Dopamine D3 receptor antagonist-1
<p>Dopamine D3 receptor antagonist-1 is a dopamine D3 receptor selective or multi-targeting ligand with a Ki value of 1.58 nM that has demonstrated therapeutic</p>Fórmula:C31H35Cl2N3O3Forma y color:SolidPeso molecular:568.53D4R antagonist-1
<p>Potent, selective D4R antagonist; IC50 = 6.87 µM; potential in Parkinson’s disease research.</p>Fórmula:C21H25F2NO2Forma y color:SolidPeso molecular:361.43CM699
CAS:<p>CM699 is an effective dual inhibitor of the dopamine transporter (DAT) and Sigma receptor (σR), with IC50 values of 311 nM and 14.1 nM, respectively.</p>Fórmula:C24H29N3O2Forma y color:SolidPeso molecular:391.51Dopamine D3 receptor ligand-1
<p>Dopamine D 3 receptor ligand is a potent, selective, high-affinity dopamine D3 receptor ligand that is 89 times more selective for D3 (Ki: 8 nM) than D2 (Ki:</p>Fórmula:C27H29N5OForma y color:SolidPeso molecular:439.55D1R antagonist 1
CAS:<p>Compound 12a (D1R antagonist 1) is a D1R antagonist that participates in both G-protein-coupled and β-arrestin-mediated signaling pathways [1].</p>Fórmula:C22H26BrNO4Pureza:98%Forma y color:SolidPeso molecular:448.35Dopamine D3 receptor antagonist-2
<p>Dopamine D3 receptor antagonist-2 is a dopamine D3 receptor selective (Ki=2.16 nM) or multi-targeting dual ligand that shows potential effects in CNS disorders.</p>Fórmula:C23H27Cl2N3O3Forma y color:SolidPeso molecular:464.38UNC10099984A
CAS:<p>UNC10099984A (Compound 6) is a functionally selective ligand for the dopamine D2 receptor, exhibiting a Ki value of 4.6 nM and an EC50 of 6.2 nM for β-arrestin. This compound is useful for research into central nervous system diseases related to the D2 receptor.</p>Fórmula:C24H29Cl2N3O2Forma y color:SolidPeso molecular:462.41Neflumozide
CAS:<p>Neflumozide (HRP 913) is an orally effective derivative of benzisoxazole, characterized by its potent dopamine antagonist properties and antipsychotic activity. It is utilized in research related to psychiatric disorders.</p>Fórmula:C22H23FN4O2Forma y color:SolidPeso molecular:394.44NMDAR antagonist 5
CAS:<p>NMDAR antagonist 5 (Compound A17) is a multi-target antagonist that acts on NMDAR and monoamine transporters (SERT, DAT, and NET). It demonstrates strong NMDAR antagonistic efficacy (IC50= 0.3 μM) and effective activity on monoamine transporters (SERT IC50= 1.1 μM, DAT IC50= 0.7 μM, NET IC50= 2.7 μM). NMDAR antagonist 5 exhibits high safety with low toxicity (hepatic and renal toxicity IC50> 100 μM; cardiac toxicity IC50= 24.5 μM). It has antidepressant properties and is useful for depression research.</p>Fórmula:C17H21N3Forma y color:SolidPeso molecular:267.369D4R antagonis-2
<p>Potent D4R antagonist-2: selective, IC50=6.52 μM, good in vitro PK and brain penetration, potential for Parkinson's research.</p>Fórmula:C21H23ClF2N2O2Forma y color:SolidPeso molecular:408.87Lisuride
CAS:<p>Lisuride: an oral D2 dopamine agonist, ergot derivative, used in Parkinson's, migraine, and high prolactin research.</p>Fórmula:C20H26N4OForma y color:SolidPeso molecular:338.45Cendifensine
CAS:<p>Cendifensine functions as a monoamine reuptake inhibitor, targeting the serotonin transporter (SERT), norepinephrine transporter (NET), and dopamine transporter (DAT).</p>Fórmula:C14H17Cl2NOForma y color:SolidPeso molecular:286.197Disulergine
CAS:<p>Disulergine is a dopamine receptor agonist. It also prolactin release-inhibiting 8 alpha-amino-ergoline.</p>Fórmula:C17H24N4O2SPureza:98%Forma y color:SolidPeso molecular:348.46Dinoxyline
CAS:<p>Dinoxyline is a potent dopamine receptor agonist, with dissociation constants (Ki values) for D1, D2, D3, and D4 receptors being 7 nM, 6 nM, 5 nM, and 43 nM, respectively. It is utilized in neuroscience research.</p>Fórmula:C15H13NO3Forma y color:SolidPeso molecular:255.27
