Receptor de dopamina
Los receptores de dopamina son un grupo de receptores acoplados a proteínas G (GPCR) que responden al neurotransmisor dopamina, jugando un papel clave en la regulación del movimiento, la motivación, la recompensa y varias funciones cognitivas. Estos receptores se dividen en familias similares a D1 y D2, cada una con funciones y perfiles farmacológicos distintos. Los moduladores de los receptores de dopamina se estudian ampliamente por sus aplicaciones en el tratamiento de la enfermedad de Parkinson, la esquizofrenia, la adicción y otros trastornos neuropsiquiátricos. En CymitQuimica, ofrecemos una amplia gama de moduladores de receptores de dopamina de alta calidad para apoyar su investigación en neurociencia, salud mental y señalización GPCR.
Se han encontrado 407 productos de "Receptor de dopamina"
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ABT-670
CAS:<p>ABT-670 is a selective agonist of dopamine D4 receptor. For human D4, ferret D4, and rat D4, the EC50 values are 89 nM, 160 nM, and 93 nM , respectively.</p>Fórmula:C19H23N3O2Pureza:98%Forma y color:SolidPeso molecular:325.4SKF 81297
CAS:<p>SKF 81297 is a selective and potent agonist for the dopamine D1 receptor [1].</p>Fórmula:C16H16ClNO2Pureza:98%Forma y color:SolidPeso molecular:289.76FAUC-312
CAS:<p>FAUC-312 is a potent and selective agonist of the dopamine D4 receptor.</p>Fórmula:C21H26N4Pureza:98%Forma y color:SolidPeso molecular:334.46LY3154885
CAS:<p>LY3154885 is an orally active dopamine D1 receptor orthosteric modulator (PAM) that reduces the risk of drug-drug interactions (DDI).</p>Fórmula:C23H23Cl2N3O2Forma y color:SolidPeso molecular:444.35Quinpirole dihydrochloride
CAS:<p>Quinpirole dihydrochloride is an agonist of the D2-like dopamine receptor.</p>Fórmula:C13H23Cl2N3Pureza:98%Forma y color:SolidPeso molecular:292.25Pentiapine
CAS:<p>Pentiapine (CGS 10746) is a novel inhibitor of dopamine release.</p>Fórmula:C15H17N5SPureza:99.35%Forma y color:SolidPeso molecular:299.39AJ-76 hydrochloride
CAS:<p>AJ-76 hydrochloride ((+)-AJ 76 hydrochloride) serves as a dopamine autoreceptor antagonist, exhibiting pK i values of 6.95 for hD3, 6.67 for hD4, 6.37 for hD2S, 6.21 for hD2L, and 6.07 for rD2 receptors, indicating its binding affinity strength across these receptor types.</p>Fórmula:C15H24ClNOForma y color:SolidPeso molecular:269.81Carbidine dihydrochloride
CAS:<p>Carbidine, a gamma-carboline derivative, is an atypical antipsychotic that modulates dopamine release and tyrosine hydroxylase activity.</p>Fórmula:C13H20Cl2N2Pureza:98.59%Forma y color:SolidPeso molecular:275.217UWA-101 hydrochloride
CAS:<p>UWA-101 hydrochloride is a selective, non-cytotoxic inhibitor of DAT/SERT, demonstrating EC50 values of 3.6 µM for DAT and 2.3 µM for SERT inhibition. It mitigates motor disorders and other side effects associated with dopaminergic agent use (e.g., L-DOPA) without exhibiting psychotropic effects. This compound is utilized in research focused on neurodegenerative conditions like Parkinson's disease [1] [2].</p>Fórmula:C13H18ClNO2Forma y color:SolidPeso molecular:255.74SB-414796
CAS:<p>SB-414796 is a selective antagonist of the dopamine D3 receptor.</p>Fórmula:C29H36N4O4SPureza:98%Forma y color:SolidPeso molecular:536.69Naxagolide free base
CAS:<p>Naxagolide is a sustained release formulation. It is a dopamine agonist.</p>Fórmula:C15H21NO2Pureza:98%Forma y color:SolidPeso molecular:247.33Dihydrexidine
CAS:<p>Dihydrexidine is a full efficacy D1-like dopamine receptor (D1/D5) agonist (IC50: 10 nM for D1 receptor). It also shows potent antiparkinsonian activity.</p>Fórmula:C17H17NO2Pureza:98%Forma y color:SolidPeso molecular:267.32Z1078601926
CAS:<p>Z1078601926 is an allosteric inhibitor of the human dopamine transporter (hDAT) and exhibits a synergistic effect when combined with Nomifensine [1].</p>Fórmula:C14H19FN2OForma y color:SolidPeso molecular:250.31Carmoxirole hydrochloride
CAS:<p>Carmoxirole hydrochloride (EMD 45609 hydrochloride) is a selective dopamine D2 receptor agonist with antihypertensive activity in vivo.</p>Fórmula:C24H27ClN2O2Pureza:99.37% - 99.62%Forma y color:SolidPeso molecular:410.94PW0464
CAS:<p>PW0464 ((Rac)-Razpipadon) is a non-catechol D1R agonist and potent omplete G protein biased ligand with an EC50 (Gs-cAMP)=5.8 nM for neurological disorders.</p>Fórmula:C19H17F2N3O4Pureza:98.78%Forma y color:SolidPeso molecular:389.35LBT 999
CAS:<p>LBT 999 is used as a dopamine reuptake inhibitor.</p>Fórmula:C20H26FNO2Forma y color:SolidPeso molecular:331.42JNJ-37822681 dihydrochloride
CAS:<p>JNJ-37822681 dihydrochloride 是特异性的、有中枢活性的，可快速解离的多巴胺 D2受体拮抗剂，与多巴胺 D2L 受体结合的亲和力适中 (Ki=158 nM)。JNJ-37822681 dihydrochloride 在精神分裂症和躁郁症领域有研究价值。</p>Fórmula:C17H19Cl2F5N4Pureza:99.78%Forma y color:SolidPeso molecular:445.26(+)-Dihydrexidine hydrochloride
CAS:<p>(+)-Dihydrexidine hydrochloride is an agonist of dopamine D1 receptor(EC50 of 72± 21 nM).</p>Fórmula:C17H18ClNO2Pureza:98%Forma y color:SolidPeso molecular:303.78Brilaroxazine
CAS:<p>Brilaroxazine (RP5063): multimodal dopamine/5-HT modulator, partial agonist at D2/D3/D4, 5-HT1A/2A, and antagonist at 5-HT2B/7.</p>Fórmula:C22H25Cl2N3O3Pureza:99.36%Forma y color:SolidPeso molecular:450.36LY-368975
CAS:<p>LY-368975 is a potent and selective inhibitor of the norepinephrine (NE) reuptake site. LY-368975 reduces food consumption in rodents.</p>Fórmula:C17H21NOSForma y color:SolidPeso molecular:287.42
