Receptor de cannabinoides
Los receptores cannabinoides son GPCR que median los efectos de los cannabinoides endógenos (endocannabinoides) y los fitocannabinoides, como los encontrados en el cannabis. Los dos tipos principales de receptores cannabinoides, CB1 y CB2, están involucrados en la regulación de una amplia gama de procesos fisiológicos, incluida la percepción del dolor, el apetito, el estado de ánimo y la función inmunitaria. Los moduladores de los receptores cannabinoides tienen potencial terapéutico en el tratamiento de afecciones como el dolor crónico, la epilepsia y la esclerosis múltiple. En CymitQuimica, ofrecemos una amplia gama de moduladores de receptores cannabinoides de alta calidad para apoyar su investigación en neurofarmacología, manejo del dolor e inmunología.
Se han encontrado 218 productos de "Receptor de cannabinoides"
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Rimonabant hydrochloride
CAS:Rimonabant hydrochloride (SR 141716A) 是中心大麻素受体 1 的高效选择性反向激动剂， Ki 值为1.8 nM。它也能够抑制分枝杆菌膜蛋白3。Fórmula:C22H22Cl4N4OPureza:98.24% - 99.5%Forma y color:Off-White To White Crystalline PowderPeso molecular:500.25Rimonabant
CAS:Rimonabant (SR141716) is an inverse agonist for the cannabinoid receptor CB1.Fórmula:C22H21Cl3N4OPureza:98% - 99.91%Forma y color:White Or Almost White Crystalline PowderPeso molecular:463.79Pregnenolone
CAS:Pregnenolone (Arthenolone) is an endogenous steroid hormone synthesized from cholesterol, used in the treatment of Alzheimer's disease.Fórmula:C21H32O2Pureza:99.5% - 99.84%Forma y color:SolidPeso molecular:316.48CB1 antagonist 2
CAS:CB1 antagonist 2 (AM4113) is caimabinoid 1 (CB1) antagonist which inhibits CB1 in vivo with an IC50 of 25.5 nM.Fórmula:C17H12Cl3N3OPureza:99.75%Forma y color:SolidPeso molecular:380.66JHU 75528
CAS:JHU 75528 (JHU-75528) is a novel PET tracer with inhibitory effects on CB that can be used to study the cannabinoid system in schizophrenic patients.Fórmula:C23H21Cl2N5O2Pureza:99.79%Forma y color:SolidPeso molecular:470.35EHP-101
CAS:EHP-101 is a PPARγ/CB2 dual agonist with anti-inflammatory properties, inhibits fat formation, and combats diet-related obesity.Fórmula:C28H35NO3Pureza:98.36%Forma y color:SolidPeso molecular:433.58Ref: TM-T13289
1mg101,00€5mg178,00€1mL*10mM (DMSO)203,00€10mg295,00€25mg485,00€50mg677,00€100mg888,00€6-Iodopravadoline
CAS:6-Iodopravadoline (AM630) is an antagonist of CB2 (Ki: 31.2 nM). And it shows 165-fold selectivity more than CB1 receptors.Fórmula:C23H25IN2O3Pureza:99.29%Forma y color:Off-White SolidPeso molecular:504.36Ref: TM-T14204
1mg38,00€2mg52,00€5mg70,00€10mg90,00€1mL*10mM (DMSO)99,00€25mg198,00€50mg326,00€100mg520,00€Anandamide
CAS:Anandamide ((5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide), an immune modulator, acts via not only cannabinoid receptors (CB1 and CB2) but alsoFórmula:C22H37NO2Pureza:95.037% - 99.22%Forma y color:Light Yellow OilPeso molecular:347.53Ref: TM-T14046
1mg34,00€2mg46,00€5mg67,00€1mL*10mM (DMSO)73,00€10mg117,00€25mg221,00€50mg330,00€100mg485,00€200mg675,00€8β-Hydroxy-exo-THC
CAS:8β-Hydroxy-exo-THC, a cannabinoid ether analog, exhibits weak affinity for receptor sites with an IC50 of 1.2 μM.Fórmula:C21H30O3Forma y color:SolidPeso molecular:330.46APP-FUBINACA
CAS:APP-FUBINACA is a cannabinoid receptor agonist, classified as a phenylalanine amide-based indazole-3-carboxamide derivative. It exhibits neurostimulatory effects.Fórmula:C24H21FN4O2Forma y color:SolidPeso molecular:416.45exo-Tetrahydrocannabivarin
CAS:exo-Tetrahydrocannabivarin (Compound 12) is an analog of Δ9,11-THC. It weakly binds to cannabinoid receptors (CB) with an IC50 of 1.4 μM. In mice, exo-Tetrahydrocannabivarin exhibits activity related to both motor function and analgesia.Fórmula:C19H26O2Forma y color:SolidPeso molecular:286.41Afubiata
CAS:ADB-FUBIATA is a synthetic cannabinoid studied for its metabolic profile, along with AFUBIATA, CH-FUBIATA, and CH-PIATA. This in vitro analysis by Watanabe S, et al., examines these compounds, as published in "Arch Toxicol," 2023 Dec;97(12):3085-3094.Fórmula:C27H29FN2OForma y color:SolidPeso molecular:416.53Cannabigerorcin
CAS:Cannabigerorcin, a phytocannabinoid, serves as an analytical reference standard. It is designated for research and forensic applications.Fórmula:C17H24O2Forma y color:SolidPeso molecular:260.377(±)-9-Nor-9α-hydroxy Hexahydrocannabinol
CAS:(±)-9-Nor-9α-hydroxy Hexahydrocannabinol is a cannabinoid-structured compound that exhibits potent cannabinoid-like activity in both dogs and mice.Fórmula:C20H30O3Forma y color:SolidPeso molecular:318.45CB2 receptor agonist 9
CAS:CB2 receptor agonist 9 (Compound 33) is an orally active agonist of cannabinoid receptor 2 (CB2 receptor) with an EC50 of 16.2 nM. It inhibits the expression of TNF-α, IL-1β, and IL-6, demonstrating anti-inflammatory activity in a DSS-induced acute colitis model in mice.Fórmula:C16H23N3O2SForma y color:SolidPeso molecular:321.44CB2R/FAAH modulator-2
CAS:CB2R/FAAH modulator-2 (compound 26) is a dual modulator targeting at CB2R and FAAH.Fórmula:C24H33NO2Pureza:99.15%Forma y color:SoildPeso molecular:367.52NESS 0327
CAS:NESS 0327 is a high selectivity antagonist of the cannabinoid CB1 receptor. NESS 0327 is more than 60,000-fold selective for the CB1 receptor.Fórmula:C24H23Cl3N4OPureza:99.78%Forma y color:SolidPeso molecular:489.82CB2R/FAAH modulator-1
CAS:CB2R/FAAH modulator-1: agonizes CB2R, inhibits FAAH (IC50=4 μM), alters cytokine production; used in inflammation research. Ki: CB2R=14.8 nM, CB1R=241.3 nM.Fórmula:C24H27NO2Pureza:99.77%Forma y color:SoildPeso molecular:361.48Ref: TM-T67896
1mg50,00€5mg105,00€1mL*10mM (DMSO)108,00€10mg154,00€25mg224,00€50mg314,00€100mg427,00€200mg575,00€Δ8-THC methyl ether
CAS:Δ8-THC methyl ether (compound 3) demonstrates a strong docking score of -10.167 kcal/mol for the CB2 receptor. Additionally, Δ8-THC methyl ether exhibits antinociceptive activity in mice.Fórmula:C22H32O2Forma y color:SolidPeso molecular:328.49CB2 receptor agonist 2
CAS:CB2 receptor agonist 2 (ZINC72105556): potent, Ki=8.5 nM, high selectivity for CB2.
Fórmula:C30H36N2O4Pureza:99.75%Forma y color:SolidPeso molecular:488.62CB2R/FAAH modulator-3
CAS:CB2R/FAAH modulator-3 (compound 27) is a modulator targeting at CB2R and FAAH.Fórmula:C22H31NO2Pureza:99.81%Forma y color:SoildPeso molecular:341.49VIP36
VIP36 is an agonist of the cannabinoid type 1 receptor (CB1) with analgesic properties. It reduces the recruitment of inhibitory proteins, thereby exerting its pain-relieving effects, and is applicable in research related to chronic pain.Fórmula:C27H35FN6O4Forma y color:SolidPeso molecular:526.603Cannabigerorcinic Acid
CAS:Cannabigerorcinic acid, structurally akin to recognized phytocannabinoids, serves as an analytical reference standard designed for research and forensic purposes.Fórmula:C18H24O4Forma y color:SolidPeso molecular:304.386Δ8-THC-C8
CAS:Δ8-THC-C8 is a semi-synthetic cannabinoid. It acts as an agonist for the cannabinoid receptor 1 (CB1) with an EC50 value of 13.8 nM.Fórmula:C24H36O2Forma y color:SolidPeso molecular:356.54(−)-6α-hydroxy Cannabidiol
CAS:(−)-6α-Hydroxy Cannabidiol, an analytical reference standard and a phytocannabinoid metabolite, serves primarily as a metabolite of cannabidiol (CBD). This product is designed for use in research and forensic applications.Fórmula:C21H30O3Forma y color:SolidPeso molecular:330.46CB2R probe 1
CAS:CB2R Probe 1, a cannabinoid 2 receptor (CB2R) fluorescent probe, exhibits both safety and environmental friendliness, boasting a dissociation constant (K i) of
Fórmula:C36H42N4O4Forma y color:SolidPeso molecular:594.74CB2 receptor antagonist 2
Compound 39, also known as CB2 receptor antagonist 2, is a potent CB2 antagonist exhibiting an IC50 of 0.33 μM.Forma y color:Odour SolidHemopressin (human, mouse)
CAS:Endogenous peptide, inhibits ep24.15/24.16/ACE with Ki of 27.76/3.43/1.87 μM. Lowers blood pressure, CB1 inverse agonist, reduces pain in vivo.Fórmula:C50H79N13O12Pureza:98%Forma y color:SolidPeso molecular:1054.26CB1-IN-3
CB1-IN-3 (Compound 6i) is a potent inhibitor of the cannabinoid receptor type 1 (CB1). It holds potential for research in obesity, inflammation, and neurological disorders.Forma y color:Odour Solid(R)-Zevaquenabant
(R)-Zevaquenabant ((R)-MRI-1867) is the enantiomer of Zevaquenabant. Zevaquenabant ((S)-MRI-1867) is a peripherally restricted, orally bioavailable dual antagonist of the cannabinoid CB1 receptor and inducible nitric oxide synthase (iNOS). It is beneficial in improving chronic kidney disease (CKD) caused by obesity.Forma y color:Odour SolidNoladin ether
CAS:Noladin ether (2-AG ether) is a cannabinoid CB1 receptor agonist.Fórmula:C23H40O3Forma y color:SolidPeso molecular:364.56N-(1-(3,4-Dihydroxyphenyl)propan-2-yl)oleamide
CAS:N-(1-(3,4-Dihydroxyphenyl)propan-2-yl)oleamide: binds CB1 (Ki=365 nM), activates PPARα (EC50=698 nM), reduces rat food intake, no FAAH inhibition.Fórmula:C27H45NO3Forma y color:SolidPeso molecular:431.6612-Arachidonoylglycerol-d5
CAS:2-Arachidonoylglycerol-d5 is the deuterated form of 2-Arachidonoylglycerol, which acts as an endogenous cannabinoid ligand within the central nervous system.Fórmula:C23H38O4Forma y color:SolidPeso molecular:383.58Drinabant
CAS:Drinabant (AVE-1625) is an orally active CB1 receptor antagonist.Fórmula:C23H20Cl2F2N2O2SPureza:99.8%Forma y color:SolidPeso molecular:497.38Calcitonin-13C6,15N4 TFA
Calcitonin-13CIC6,15NIC4(salmon) (Salmon calcitonin-13CIC6,15NIC4) TFA is a version of calcitonin(salmon) labeled with carbon-13 and nitrogen-15. This hormone regulates calcium and acts dualistically as an agonist to both amylin and calcitonin receptors, promoting bone formation while inhibiting bone resorption.Fórmula:C1401C5H240N4315NO48S2·5C2HF3O2Forma y color:SolidPeso molecular:4007.93GPR55 agonist 4
GPR55 agonist 4 (Compound 28), with an EC50 of 131 nM for hGPR55 and 1.41 nM for rGPR55, effectively induces β-arrestin recruitment to human GPR55 [1].Fórmula:C19H16FN5O2Forma y color:SolidPeso molecular:365.36Hemopressin(rat)
CAS:Peptide inhibitor for ep24.15, neurolysin & ACE with Ki 27.76, 3.43, 1.87 μM. Lowers blood pressure, modulates CB1 receptor, reduces pain & food intake.Fórmula:C53H77N13O12Pureza:98%Forma y color:SolidPeso molecular:1088.27Vicasinabin
CAS:Vicasinabin: potent CB2 agonist; researches chronic pain, atherosclerosis, bone mass, neuroinflammation.Fórmula:C15H22N10OForma y color:SolidPeso molecular:358.41Zevaquenabant
CAS:Zevaquenabant (S-MRI-1867): oral CB1/iNOS antagonist combatting obesity-induced CKD.Fórmula:C25H21ClF3N5O2SForma y color:SolidPeso molecular:547.98GFB-024
GFB-024 is a humanized antibody targeting CB1, which can be used to study obesity.Forma y color:LiquidPeso molecular:146.12 kDaRVD-Hpα
CAS:N-terminally extended form of human hemopressin that acts as a selective CB1 receptor agonist.Fórmula:C65H105N19O17Pureza:98%Forma y color:SolidPeso molecular:1424.66Tocrifluor T1117
CAS:Fluorescent form of AM 251, CB1 receptor antagonistFórmula:C56H53Cl2N7O5Pureza:98%Forma y color:SolidPeso molecular:974.97TRPV1/CB2 agonist 1
TRPV1/CB2 agonist 1 (compound 41) is a dual agonist targeting hTRPV1 and CB2 receptors, with an EC50 value of 26.8 μM for hTRPV1. It is applicable in research related to the nervous system.Forma y color:Odour SolidCB1R agonist 1
CB1R agonist 1 (Compound '1350) is a potent full agonist of the cannabinoid-1 receptor (CB1R) with a Ki value of 0.95 nM. It demonstrates significant pain-relieving effects in various pain models, including acute thermal pain, inflammatory pain, and neuropathic pain.Fórmula:C20H18F3N3O3SForma y color:SolidPeso molecular:437.435Hemopressin(human, mouse) TFA
CAS:Hemopressin TFA: nonapeptide from hemoglobin, oral CB1 inverse agonist, eases inflammatory pain.Fórmula:C52H80F3N13O14Pureza:98%Forma y color:SolidPeso molecular:1168.27δ8-THC acetate
CAS:Delta8-THC acetate (Delta8-tetrahydrocannabinol) is a psychoactive cannabinoid that binds to the cannabinoid receptor 1 (CB1 receptor) and exhibits anti-nausea, appetite-stimulating, and anti-inflammatory effects. It may also offer neuroprotective benefits and has potential applications in research on anxiety and depression.Fórmula:C23H32O3Forma y color:SolidPeso molecular:356.5Cannabinol methyl ether
CAS:Cannabinol methyl ether, a phytocannabinoid, serves as an analytical reference standard. This compound can be obtained through isolation from Cannabis plants, derived from cannabinol, or synthesized. The physiological and toxicological properties of cannabinol methyl ether remain unknown. It is designed exclusively for research and forensic applications.Fórmula:C22H28O2Forma y color:SolidPeso molecular:324.5Δ9-THCH
CAS:Δ9-THCH, a phytocannabinoid analytical reference standard, is present in a Cannabis variety cultivated for medicinal use. In the United States, it is classified as a Schedule I compound. This product is designated for research and forensic applications.Fórmula:C22H32O2Forma y color:SolidPeso molecular:328.49CB1R antagonist 2
CB1R antagonist 2 (Compound 11g) functions as an antagonist of the cannabinoid receptor 1 (CB1R), inhibiting the MAPK/NF-κB signaling pathway and exhibiting anti-inflammatory properties. In RAW264.7 cells, it suppresses LPS-induced expression of IL-6, IL-1β, and TNF-α. In murine models, it improves OVA-induced allergic rhinitis.Fórmula:C24H26N4OForma y color:SolidPeso molecular:386.49Cannabidivarinic acid
CAS:Cannabidivarinic acid (CBDVA), the carboxylic acid precursor to cannabidivarin (CBDV), is a non-psychoactive cannabinoid found in Cannabis and known for its anti-inflammatory properties.Fórmula:C20H26O4Forma y color:SolidPeso molecular:330.42
