Síntesis de ADN / ARN
Los inhibidores de la síntesis de ADN y ARN son compuestos que interfieren con los procesos de replicación y transcripción en las células, impidiendo así la producción de material genético esencial. Estos inhibidores pueden dirigirse a diversas enzimas y proteínas involucradas en la síntesis de ácidos nucleicos, lo que los convierte en herramientas valiosas para estudiar los mecanismos de replicación, transcripción y traducción. También se utilizan en el desarrollo de tratamientos para infecciones y cáncer. En CymitQuimica, ofrecemos un amplio espectro de inhibidores de la síntesis de ADN/ARN para apoyar su investigación en biología molecular, virología y desarrollo terapéutico.
Se han encontrado 707 productos de "Síntesis de ADN / ARN"
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3-Deazauridine
CAS:<p>3-Deazauridine (NSC-126849), a uridine analog, blocks CTP synthesis by competing with CTP synthetase.</p>Fórmula:C10H13NO6Pureza:99.86%Forma y color:SolidPeso molecular:243.21T-5224
CAS:<p>T-5224 is a transcription factor c-Fos/AP-1 inhibitor, which specifically inhibits the DNA binding activity of c-Fos/c-Jun without affecting other transcription</p>Fórmula:C29H27NO8Pureza:97.88% - 99.29%Forma y color:SolidPeso molecular:517.53AI-10-49
CAS:<p>AI-10-49 is a selective inhibitor of the binding of CBFβ-SMMHC to RUNX1 with IC50 of 260 nM.</p>Fórmula:C30H22F6N6O5Pureza:97.14%Forma y color:SolidPeso molecular:660.52Brr2-IN-3
CAS:<p>Brr2-IN-3 (Brr2 Inhibitor C9) is an allosteric inhibitor of the spliceosomal RNA helicase Brr2. Brr2 is implicated in autosomal-dominant retinitis pigmentosa.</p>Fórmula:C24H20N4O3SPureza:99.26%Forma y color:SolidPeso molecular:444.51Deoxythymidine triphosphate
CAS:<p>Deoxythymidine triphosphate (dTTP) is one of the four nucleoside triphosphates that are used in the in vivo synthesis of DNA.</p>Fórmula:C10H14N2Na3O14P3Pureza:99.78%Forma y color:White Amorphous PowderPeso molecular:548.115-BrdU
CAS:<p>5-BrdU (Broxuridine) is a nucleoside analogue, detect proliferating cells and compete with thymidine for incorporation into DNA. High-Quality, Low-Cost!</p>Fórmula:C9H11BrN2O5Pureza:99.54% - 99.87%Forma y color:Crystals From Absolute Ethanol Physical Description White Crystalline Powder (Ntp 1992)Peso molecular:307.1Phosphonoformic acid trisodium salt hexa
CAS:<p>Phosphonoformic acid trisodium salt hexa (Sodium phosphonatoformate hexahydrate) is an antiviral drug for the treatment of CMV retinitis.</p>Fórmula:CH12Na3O11PPureza:98%Forma y color:SolidPeso molecular:300.03Tipiracil
CAS:<p>Tipiracil inhibits thymidine phosphorylase, enhancing trifluridine bioavailability, and is studied in colorectal and gastric cancer treatment.</p>Fórmula:C9H11ClN4O2Pureza:99.815%Forma y color:SolidPeso molecular:242.661,4-Anthraquinone
CAS:<p>1,4-Anthraquinone: anticancer, hinders nucleoside transport, inhibits synthesis, fragments DNA, curbs L1210 cell growth; aids HPLC analysis of NAC, CAP.</p>Fórmula:C14H8O2Pureza:95.96% - 97.01%Forma y color:Orange Brown SolidPeso molecular:208.21TH588 hydrochloride
CAS:<p>TH588 hydrochloride is first-in-class inhibitor of nudix hydrolase family that selectively and effectively bind and inhibit the MTH1 with IC50 value of 5 nM.</p>Fórmula:C13H13Cl3N4Forma y color:SolidPeso molecular:331.63SCR7 pyrazine
CAS:<p>SCR7 pyrazine (SCR7) enhances CRISPR-Cas9-mediated homology-directed repair (HDR) efficiency in vitro up to 19-fold. Inhibits nonhomologous end-joining (NHEJ).</p>Fórmula:C18H12N4OSPureza:98.72% - 99.85%Forma y color:SolidPeso molecular:332.38Triazavirin
CAS:<p>Triazavirin is a nucleoside analogue of nucleic acid and an antiviral agent.</p>Fórmula:C5H7N6NaO5SPureza:99.55%Forma y color:SolidPeso molecular:286.2CX-5461 dihydrochloride
<p>CX-5461 dihydrochloride: Oral Pol I inhibitor, HCT-116 (IC50: 142 nM), A375 (IC50: 113 nM), MIA PaCa-2 (IC50: 54 nM), weak on Pol II (IC50 ≥ 25 μM).</p>Fórmula:C27H29Cl2N7O2SForma y color:SolidPeso molecular:586.54Simeprevir
CAS:<p>Simeprevir (TMC435) is a potent HCV NS3/4A protease inhibitor, and inhibits HCV replication with EC50 of 8 nM.</p>Fórmula:C38H47N5O7S2Pureza:99.45% - 99.92%Forma y color:SolidPeso molecular:749.94Simeprevir sodium
CAS:<p>Simeprevir is a drug for the treatment and cure of hepatitis C.</p>Fórmula:C38H46N5NaO7S2Pureza:98%Forma y color:SolidPeso molecular:771.92Pyridostatin hydrochloride
CAS:<p>Pyridostatin hydrochloride stabilizes G-quadruplex DNA (Kd=490nM), inhibits cancer cell growth, and reduces SRC in breast cancer.</p>Fórmula:C31H37Cl5N8O5Forma y color:SolidPeso molecular:778.941-Hydroxyanthraquinone
CAS:<p>1-Hydroxyanthraquinone is an anthraquinone that has been found in Morinda officinalis and has genotoxic and carcinogenic activities.</p>Fórmula:C14H8O3Pureza:99.56%Forma y color:Orange Red Needles Red-Orange To Fine Yellow CrystalsPeso molecular:224.21Dasabuvir sodium
CAS:<p>Dasabuvir sodium (ABT-333) inhibits HCV NS5B polymerase, targeting genotypes 1a (EC50: 7.7 nM) and 1b (EC50: 1.8 nM).</p>Fórmula:C26H26N3NaO5SForma y color:SolidPeso molecular:515.56Idarubicin hydrochloride
CAS:<p>Idarubicin hydrochloride (Zavedos), a hydrochloride salt form of Idarubicin, is a DNA topoisomerase II (topo II) inhibitor for MCF-7 cells ( IC50: 3.3 ng/mL).</p>Fórmula:C26H27NO9·HClPureza:98.91% - 99.96%Forma y color:SolidPeso molecular:533.95BRD32048
CAS:<p>BRD32048 is a top candidate ETV1 perturbagen. BRD32048 inhibits p300-dependent acetylation of ETV1, thereby promoting its degradation.</p>Fórmula:C16H22N6OPureza:99.87%Forma y color:SolidPeso molecular:314.39RI-1
CAS:<p>RI-1 (RAD51 inhibitor 1) is a RAD51 inhibitor (IC50: 5-30 μM).</p>Fórmula:C14H11Cl3N2O3Pureza:99.3% - 99.62%Forma y color:SolidPeso molecular:361.61Risdiplam
CAS:<p>Risdiplam (RG7916) is a centrally and peripherally distributed and orally administrable small molecule SMN2 pre-mRNA splicing modifier.Cost-effective and quality-assured.</p>Fórmula:C22H23N7OPureza:98.68% - 99.64%Forma y color:SolidPeso molecular:401.46TH5487
CAS:<p>TH5487 is an potent inhibitor of 8-oxoguanine DNA glycosylase 1 (OGG1)( IC50 of 342 nM)</p>Fórmula:C19H18BrIN4O2Pureza:98.38% - 98.73%Forma y color:SolidPeso molecular:541.18HAMNO
CAS:<p>HAMNO (NSC-111847) is a protein interaction inhibitor of replication protein A (RPA).</p>Fórmula:C17H13NO2Pureza:99.96%Forma y color:SolidPeso molecular:263.29BMH-21
CAS:<p>BMH-21, a small molecule DNA intercalator, binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription and not affects phosphorylation of H2AX.</p>Fórmula:C21H20N4O2Pureza:99.47% - 99.84%Forma y color:SolidPeso molecular:360.41TH287
CAS:<p>TH287 is a potent inhibitor of MTH1 (NUDT1), less potent for MTH2, NUDT5, NUDT12, NUDT14, and NUDT16.</p>Fórmula:C11H10Cl2N4Pureza:97.73% - 99%Forma y color:SolidPeso molecular:269.13Adenine hydrochloride
CAS:<p>Adenine hydrochloride (6-Aminopurine hydrochloride) is a hydrochloride salt form of adenine which is a nucleobase with a variety of roles in biochemistry.</p>Fórmula:C5H5N5·HClPureza:98.86%Forma y color:White To Light Yellow Crystal PowderPeso molecular:171.59Lurbinectedin
CAS:<p>Lurbinectedin (PM01183) is a DNA minor groove covalent binder. Lurbinectedin also shows effective anti-tumor activity.</p>Fórmula:C41H44N4O10SPureza:98.11%Forma y color:SolidPeso molecular:784.87FIT-039
CAS:<p>FIT-039 is a selective and ATP-competitive, orally active inhibitor of CDK9( IC50 : 5.8 μM;CDK9/cyclin T1).</p>Fórmula:C17H18FN3SPureza:98.61%Forma y color:SolidPeso molecular:315.41Fosifloxuridine nafalbenamide
CAS:<p>Fosifloxuridine nafalbenamide (NUC 3373), a pyrimidine nucleotide analogue, is a Thymidylate synthase inhibitor.</p>Fórmula:C29H29FN3O9PPureza:95.87%Forma y color:SolidPeso molecular:613.53Brequinar
CAS:<p>Brequinar (NSC-368390) is a potent inhibitor of dihydroorotate dehydrogenase, with potent activities against a broad spectrum of viruses.</p>Fórmula:C23H15F2NO2Pureza:99.1% - 99.57%Forma y color:SolidPeso molecular:375.37L-Asparaginase
CAS:<p>L-Asparaginase, an enzyme for acute lymphoblastic leukemia treatment, is administered via injection.</p>Fórmula:NAPureza:97%Forma y color:SolidPeso molecular:N/ARCM-1
CAS:<p>RCM-1 is an inhibitor of FOXM1.</p>Fórmula:C20H12N2OS4Pureza:98.08%Forma y color:SolidPeso molecular:424.58EG1
CAS:<p>EG1, a novel specific inhibitor of Pax2 transcription activation, targets the DNA binding domain and inhibits embryonic kidney development.</p>Fórmula:C22H18N2O5Pureza:97.48%Forma y color:SolidPeso molecular:390.39CB-6644
CAS:<p>CB-6644 is a small molecule inhibitor of the ATPase activity of the RUVBL1/2 complex.Cost-effective and quality-assured.</p>Fórmula:C29H34ClFN4O5Pureza:96.33% - 99.85%Forma y color:SolidPeso molecular:573.06FUBP1-IN-1
CAS:<p>FUBP1-in-1: Potent FUBP1 inhibitor with 11.0 M IC50, disrupts FUBP1-DNA binding.</p>Fórmula:C19H14F3N3O2SPureza:99.7%Forma y color:SolidPeso molecular:405.392′-O-Methylcytidine
CAS:<p>2′-O-Methylcytidine inhibits NS5B-catalyzed RNA synthesis in vitro, in a manner that is competitive with substrate nucleoside triphosphate.</p>Fórmula:C10H15N3O5Pureza:99.72%Forma y color:SolidPeso molecular:257.24Gadodiamide
CAS:<p>Gadodiamide is an MRI contrast agent, used in MR imaging procedures to assist in the visualization of blood vessels.</p>Fórmula:C16H26GdN5O8Pureza:99.86%Forma y color:SolidPeso molecular:573.66Antitumor agent-152
CAS:<p>Organic compound, potential dCK inhibitor, with 2-ethyl-3-methoxyphenyl-1,3-thiazole and pyrimidine units.</p>Fórmula:C17H19N5O2S2Pureza:95.00%Forma y color:SolidPeso molecular:389.5C/EBPα inducer 1
CAS:<p>C/EBPα inducer 1 (4(3H)-Quinazolinone, 6-fluoro-2-[(1E)-2-(5-nitro-2-furanyl)ethenyl]-3-phenyl-) is a potential inducer of myeloid differentiation via</p>Fórmula:C20H12FN3O4Pureza:98.99%Forma y color:SolidPeso molecular:377.33Myoseverin
CAS:<p>Myoseverin triggers myotube fission into single cells, influencing genes for growth, immunity, matrix remodeling, and stress, aiding healing and regeneration.</p>Fórmula:C24H28N6O2Pureza:99.25%Forma y color:SolidPeso molecular:432.52VPC-80051 racemate
CAS:<p>VPC-80051 is the first small molecule inhibitor of hnRNP A1 splicing activity by using a computer-aided drug discovery approach.</p>Fórmula:C16H13F2N3OPureza:97.36%Forma y color:SolidPeso molecular:301.295'-Deoxy-5-fluorocytidine
CAS:<p>5'-Deoxy-5-fluorocytidine is an intermediate metabolite of the DNA synthesis inhibitor capecitabine.</p>Fórmula:C9H12FN3O4Pureza:99.67%Forma y color:White SolidPeso molecular:245.21TC-E 5003
CAS:<p>TC-E 5003 (NSC-30176) is a selective inhibitor of PRMT1 with IC50 of 1.5 μM.</p>Fórmula:C16H14Cl2N2O4SPureza:97.01%Forma y color:SolidPeso molecular:401.26HALOFUGINONE LACTATE
CAS:<p>HALOFUGINONE LACTATE is a halogenated derivative of febrifugine, a natural quinazolinone-containing compound found in the Chinese herb D.</p>Fórmula:C19H23BrClN3O6Pureza:99.70% - 99.96%Forma y color:SolidPeso molecular:504.8Euscaphic acid
CAS:<p>Euscaphic acid has anti-diabetic and anti-inflammatory effects, blocking IKK/MAPKs and NF-κB activation by disrupting TRAF6/IRAK1/TAK1 clustering.</p>Fórmula:C30H48O5Pureza:98.93%Forma y color:SolidPeso molecular:488.7Rg3039
CAS:Rg3039 (PF-06687859) is a potent DcpS inhibitor. DcpS is a therapeutic target for spinal muscular atrophy (SMA). RG3039 improves motor function in SMA mice.Fórmula:C21H23Cl2N5OPureza:98.24% - 99.58%Forma y color:SolidPeso molecular:432.35Clevudine
CAS:<p>Clevudine (Levovir) fights HBV, blocks viral DNA synthesis, and has a long half-life reducing relapse risk after treatment.</p>Fórmula:C10H13FN2O5Pureza:99.88% - 99.97%Forma y color:SolidPeso molecular:260.22dGTP
CAS:<p>dGTP (2'-Deoxyguanosine-5'-triphosphate) is one of the guanosine nucleotides which is highly susceptible to oxidative damage to 8-O-GDP, 8-O-dGTP, 8-O-GTP, and</p>Fórmula:C10H16N5O13P3Pureza:99.64%Forma y color:SolidPeso molecular:507.18L67
CAS:<p>L67 (DNA Ligase Inhibitor) is a competitive human DNA ligase inhibitor, inhibits DNA ligases I and III (IC50: 10 μM).</p>Fórmula:C16H14Br2N4O4Pureza:98.34% - 99.56%Forma y color:SolidPeso molecular:486.11
