Síntesis de ADN / ARN
Los inhibidores de la síntesis de ADN y ARN son compuestos que interfieren con los procesos de replicación y transcripción en las células, impidiendo así la producción de material genético esencial. Estos inhibidores pueden dirigirse a diversas enzimas y proteínas involucradas en la síntesis de ácidos nucleicos, lo que los convierte en herramientas valiosas para estudiar los mecanismos de replicación, transcripción y traducción. También se utilizan en el desarrollo de tratamientos para infecciones y cáncer. En CymitQuimica, ofrecemos un amplio espectro de inhibidores de la síntesis de ADN/ARN para apoyar su investigación en biología molecular, virología y desarrollo terapéutico.
Se han encontrado 793 productos de "Síntesis de ADN / ARN"
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Fozivudine tidoxil
CAS:Fozivudine tidoxil, a reverse transcriptase inhibitor, is used potentially for the treatment of HIV infection.Fórmula:C35H64N5O8PSForma y color:SolidPeso molecular:745.95AS-136A
CAS:AS-136A is an orally active MV RdRp inhibitor with antiviral activity that inhibits measles virus and blocks viral RNA synthesis.Fórmula:C17H19F3N4O3SPureza:98.52%Forma y color:SolidPeso molecular:416.42Phen-DC3
CAS:Phen-DC3 is a G-quadruplex (G4) specific ligand which can inhibit FANCJ and DinG helicases (IC50s of 65±6 and 50±10 nM, respectively).Fórmula:C34H26N6O2Pureza:98%Forma y color:SolidPeso molecular:550.61360A iodide
CAS:360A iodide is a selective stabilizer of G-quadruplex and inhibits telomerase activity (IC50: 300 nM in TRAP-G4 assay).Fórmula:C27H23I2N5O2Pureza:98%Forma y color:SolidPeso molecular:703.31Nitracrine dihydrochloride
CAS:Nitracrine dihydrochloride is an acridine antineoplastic agent used in mammary and ovarian tumors. It inhibits RNA synthesis.Fórmula:C18H22Cl2N4O2Forma y color:SolidPeso molecular:397.3UIAA-II-232
CAS:UIAA-II-232 (compound 19b) is a potent inhibitor of DNA gyrase catalytic (IC 50= 3.5 μM).Fórmula:C20H24FN5O3Forma y color:SolidPeso molecular:401.43R-82913
CAS:R-82913 blocks RNA-polymerase, lowers mouse DOI-head-shakes, halts 13 HIV-1 strains with 0.15µM IC50, beats AZT-TP by 20x; ineffective on HIV-2.Fórmula:C16H20ClN3SForma y color:SolidPeso molecular:321.87UCK2 Inhibitor-1
CAS:UCK2 Inhibitor-1 is a non-competitive UCK2 inhibitor with an IC 50 of 4.7 µM .Fórmula:C27H21N3O4SForma y color:SolidPeso molecular:483.54RTC14
CAS:RTC14 induces PTC readthrough, restoring dystrophin and aiding muscle function in Duchenne model mice.Fórmula:C17H18N2O3Forma y color:SolidPeso molecular:298.3412(S)-HpETE
CAS:12(S)-HpETE activates human blood leukocyte 5-LOE and mediates induction of c-fos and c-jun, activation of AP-1, and endothelium-dependent vasoconstriction.Fórmula:C20H32O4Forma y color:SolidPeso molecular:336.4710-Formyl-5,8-dideazafolic acid
CAS:10-Formyl-5,8-dideazafolic acid is a thymidylate synthase inhibitor.Fórmula:C22H21N5O7Pureza:96.04%Forma y color:SolidPeso molecular:467.43Zelpolib
CAS:Zelpolib is a specific inhibitor of DNA polymerase δ (Pol δ), inhibiting DNA replication. antiproliferative.Fórmula:C22H21N3O5S2Pureza:98.79%Forma y color:SolidPeso molecular:471.55Thiarabine
CAS:Thiarabine displays effective anti-tumor activity. It also inhibition of DNA synthesis.Fórmula:C9H13N3O4SPureza:98%Forma y color:SolidPeso molecular:259.28Enocitabine
CAS:Enocitabine is a nucleoside analog.Fórmula:C31H55N3O6Pureza:97.22%Forma y color:SolidPeso molecular:565.78DHX9-IN-1
CAS:DHX9-IN-1 is a potent ATP-dependent RNA helicase A (DHX9) inhibitor, exhibiting an IC50 of 9.45 nM and demonstrating antitumor activity [1].Fórmula:C21H21F2N5O3SForma y color:SolidPeso molecular:461.49Crisnatol
CAS:Crisnatol (BWA770U) is an oral anticancer DNA intercalator, toxic to breast cancer cells, not skin fibroblasts.Fórmula:C23H23NO2Forma y color:SolidPeso molecular:345.43DENV-IN-4
CAS:DENV-IN-4: Effective DENV inhibitor (EC50=4.79 μM), low toxicity (CC50>100 μM), and strong selectivity (SI>20.9); suppresses DENV2 and RdRp.Fórmula:C28H32N4O4SiForma y color:SolidPeso molecular:516.66HBV-IN-15
CAS:HBV-IN-15, a flavone derivative, is a potent cccDNA inhibitor, potentially aiding HBV research.Fórmula:C24H23ClO6Forma y color:SolidPeso molecular:442.89BMH-23
CAS:BMH-23 is an RNA polymerase I inhibitor that acts by causing nucleolar stress and showing potent anticancer activity across many tumor types.Fórmula:C15H15N3Pureza:98%Forma y color:SolidPeso molecular:237.3HIV-1 inhibitor-43
CAS:<p>HIV-1 Inhibitor-43 suppresses HIV-1, with EC50: 21.3 nM (Y188L), 6.2 nM (K103N-Y181C), <0.7 nM (K103N/Y181C), and lowers HIV RNA/p24 protein.</p>Fórmula:C24H21ClN2O4SForma y color:SolidPeso molecular:468.95
