Síntesis de ADN / ARN
Los inhibidores de la síntesis de ADN y ARN son compuestos que interfieren con los procesos de replicación y transcripción en las células, impidiendo así la producción de material genético esencial. Estos inhibidores pueden dirigirse a diversas enzimas y proteínas involucradas en la síntesis de ácidos nucleicos, lo que los convierte en herramientas valiosas para estudiar los mecanismos de replicación, transcripción y traducción. También se utilizan en el desarrollo de tratamientos para infecciones y cáncer. En CymitQuimica, ofrecemos un amplio espectro de inhibidores de la síntesis de ADN/ARN para apoyar su investigación en biología molecular, virología y desarrollo terapéutico.
Se han encontrado 793 productos de "Síntesis de ADN / ARN"
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Photoregulin3
CAS:Photoregulin3 is a inhibitor of rod photoreceptor gene expression, potentially though Nr2e3 modulation.Fórmula:C22H23N3O3Forma y color:SolidPeso molecular:377.443'-Deoxyuridine-5'-triphosphate
CAS:3'-dUTP, a nucleotide analogue, competitively inhibits RNA polymerases I & II, with a Ki of 2.0 µM.Fórmula:C9H15N2O14P3Forma y color:SolidPeso molecular:468.14JFN05510
CAS:Compound: 3'-O-tert-BDMS-5'-O-DMT-N2-IBG 2'-CE phosphoramidite; has anticancer properties and activates enzymes.Fórmula:C50H68N7O9PSiForma y color:SolidPeso molecular:970.18Cylindrospermopsin
CAS:Cylindrospermopsin: a toxic cyanobacterial uracil derivative, disrupts protein/glutathione synthesis in hepatocytes, and is genotoxic.Fórmula:C15H21N5O7SForma y color:SolidPeso molecular:415.42Beaucage reagent
CAS:Beaucage reagent, which is found to be effective in causing DNA cleavage.Fórmula:C7H4O3S2Pureza:98.50%Forma y color:White To Off-White PowderPeso molecular:200.23BAY-707
CAS:BAY-707: tolerable in mice, no anticancer efficacy; potent, selective MTH1 inhibitor, IC50 = 2.3 nM; good PK profile.Fórmula:C15H20N4O2Pureza:98%Forma y color:SolidPeso molecular:288.34TDRL-X80
CAS:TDRL-X80 inhibits XPA DNA binding; effective on single, double, and cisplatin-damaged DNA; IC50: 18-29 μM (FP), 21-39 μM (ELISA).Fórmula:C23H15ClN2O6Forma y color:SolidPeso molecular:450.83Valomaciclovir
CAS:Valomaciclovir is a DNA polymerase inhibitor potentially for treatment of acute herpes zoster and EB virus infection.Fórmula:C15H24N6O4Forma y color:SolidPeso molecular:352.39MLAF50
CAS:MLAF50 is an inhibitor of the REV1 UBM2-Ubiquitin interaction.Fórmula:C15H12I2O4Forma y color:SolidPeso molecular:510.062-Fluoroadenine
CAS:<p>2-Fluoroadenine (NSC-27364) has toxicity in nonproliferating and proliferating tumor cells. 2-Fluoroadenine can be used for anticancer studies.</p>Fórmula:C5H4FN5Pureza:98.84% - 99.62%Forma y color:White To Light Yellow Crystal PowderPeso molecular:153.12ATB107
CAS:ATB107 is a potent and novel inhibitor of indole-3-glycerol phosphate synthase (IGPS, KD: 3 μM).Fórmula:C21H28N8Pureza:98%Forma y color:SolidPeso molecular:392.5Antibacterial agent 124
CAS:Antibacterial agent 124 inhibits Sa ProRS with an IC50 of 0.18 μM.Fórmula:C16H17ClFN3O2Forma y color:SolidPeso molecular:337.78NSC666715
CAS:NSC666715 is the strand-displacement activity of DNA polymerase inhibitor.Fórmula:C15H13Cl2N5O2S2Pureza:98%Forma y color:SolidPeso molecular:430.33HBV-IN-4
CAS:HBV-IN-4, a phthalazinone, inhibits HBV DNA replication orally (IC50: 14 nM), encouraging genome-free capsids with strong anti-HBV effects.Fórmula:C24H19ClFN5O3Forma y color:SolidPeso molecular:479.89HBV-IN-16
CAS:HBV-IN-16, a quinoline derivative, inhibits HBV cccDNA, key for viral replication (from patent WO2019121357A1).Fórmula:C22H20ClNO4Forma y color:SolidPeso molecular:397.85Laromustine
CAS:Laromustine (VNP40101M) is a sulfonyl hydrolysis alkylation prodrug for cancer treatment with significant anticancer activity, inhibiting thioredoxin reductase.Fórmula:C6H14ClN3O5S2Pureza:≥98%Forma y color:SolidPeso molecular:307.78BPIC
CAS:BPIC is an agent of anti-tumor that acts by inhibiting inflammation and scavenging free radicals.Fórmula:C27H20N2O5Forma y color:SolidPeso molecular:452.46BMH-22
CAS:BMH-22 is an RNA polymerase I inhibitor that acts by causing nucleolar stress and showing potent anticancer activity across many tumor types.Fórmula:C16H17N3Forma y color:SolidPeso molecular:251.33Triaziquone
CAS:Triaziquone is an alkylating agent that can react with DNA to form intrastrand crosslinks.Fórmula:C12H13N3O2Forma y color:SolidPeso molecular:231.25EGFR/HER2/TS-IN-2
CAS:EGFR/HER2/TS-IN-2: Strong EGFR, HER2 & TS inhibitor; EGFR IC50=0.173μM, HER2 IC50=0.125μM, TS IC50=1.12μM; kills MDA-MB-231 cells (IC50=1.69μM).Fórmula:C26H21N7OS2Forma y color:SolidPeso molecular:511.62
