Síntesis de ADN / ARN
Los inhibidores de la síntesis de ADN y ARN son compuestos que interfieren con los procesos de replicación y transcripción en las células, impidiendo así la producción de material genético esencial. Estos inhibidores pueden dirigirse a diversas enzimas y proteínas involucradas en la síntesis de ácidos nucleicos, lo que los convierte en herramientas valiosas para estudiar los mecanismos de replicación, transcripción y traducción. También se utilizan en el desarrollo de tratamientos para infecciones y cáncer. En CymitQuimica, ofrecemos un amplio espectro de inhibidores de la síntesis de ADN/ARN para apoyar su investigación en biología molecular, virología y desarrollo terapéutico.
Se han encontrado 793 productos de "Síntesis de ADN / ARN"
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Remdesivir maleate
CAS:Remdesivir (GS-5734) is a broad-spectrum antiviral prodrug effective against SARS-CoV-2 and Ebola, used for research, not human treatment.Fórmula:C31H39N6O12PForma y color:SolidPeso molecular:718.656HBV-IN-22
CAS:HBV-IN-22 (Compound LC5f) is an HBV DNA replication inhibitor that acts on both wild-type HBV (IC50: 0.71 μM) and drug-resistant HBV (IC50: 0.84 μM).Fórmula:C26H29N3O2S2Forma y color:SolidPeso molecular:479.66CBL 0100 free base
CAS:CBL0100 is an inhibitor of viral transcriptional elongation, blocking both HIV-1 replication and reactivation.Fórmula:C24H26N2O2Pureza:98.18% - 98.86%Forma y color:SolidPeso molecular:374.48Crisnatol mesylate
CAS:Crisnatol, a potent and selective DNA intercalator, has potential anticancer activity.Fórmula:C24H27NO5SForma y color:SolidPeso molecular:441.54ST7612AA1
CAS:ST7612AA1: potent, oral HDAC inhibitor; reactivates HIV-1 latency; shows antitumor effects; may study malaria.Fórmula:C20H27N3O4SPureza:99.71%Forma y color:SolidPeso molecular:405.51POLA1 inhibitor 1
CAS:POLA1 inhibitor 1: oral, antitumor, effective on various cancers and Adaroten-resistant cells.Fórmula:C26H27NO4Forma y color:SolidPeso molecular:417.5Braco-19 trihydrochloride
CAS:BRACO19 3HCl inhibits telomerase, blocking its capping function, and prevents HAdV viral replication.Fórmula:C35H46Cl3N7O2Pureza:98.74%Forma y color:SolidPeso molecular:703.14ERCC1-XPF-IN-1
CAS:ERCC1-XPF-IN-1: potent ERCC1-XPF inhibitor (IC50: 0.49 μM), hampers CPD removal, boosts UV toxicity, hinders DNA repair.Fórmula:C28H32ClN5O2Forma y color:SolidPeso molecular:506.04Teloxantrone HCl
CAS:Teloxantrone, a DNA topoisomerase II inhibitor, is used potentially for the treatment of solid tumors.Fórmula:C21H28ClN5O5Forma y color:SolidPeso molecular:465.94FLDP-5
CAS:FLDP-5: BBB-penetrant curcuminoid, induces ROS, DNA damage, S phase arrest, suppresses tumors in LN-18 cells.Fórmula:C21H21NO5Forma y color:SolidPeso molecular:367.4Direct Black 38 free acid
CAS:Ferristatin II (Direct Black 38 free acid) is a polysulphonated dye and promotes the degradation of transferrin receptor-1 in vitro and in vivo.Fórmula:C34H27N9O7S2Pureza:98%Forma y color:SolidPeso molecular:737.77IACS-4759
CAS:IACS-4759 is a novel potent and selective MTH1 inhibitor with excellent cell permeability and good metabolic stability in microsomes.Fórmula:C10H17N3O2Forma y color:SolidPeso molecular:211.26Synucleozid
CAS:Synucleozid is a potent the SNCA mRNA inhibitor that encodes α-synuclein protein (IC50=1.5 μM), has the potential for the investigation of Parkinson’s disease.Fórmula:C22H20N6Pureza:98%Forma y color:SolidPeso molecular:368.43S-(N-PhenethylthiocarbaMoyl)-L-cysteine
CAS:PEITC-Cys: anticarcinogenic, antileukemic, inhibits DNA synthesis in HL60, P450 inhibitor.Fórmula:C12H16N2O2S2Forma y color:SolidPeso molecular:284.4BAY-707 acetate
CAS:BAY-707: potent, selective MTH1 inhibitor with excellent engagement and pharmacokinetics but no anticancer efficacy alone or combined.Fórmula:C17H24N4O4Forma y color:SolidPeso molecular:348.188-Azido-ADP disodium
CAS:8-Azido-ADP (disodium) is a covalent inhibitor of ADP/ATP exchange in mitochondria, causing irreversible inhibition in light.Fórmula:C10H13N8NaO10P2Forma y color:SolidPeso molecular:490.197Werner syndrome RecQ helicase-IN-3
CAS:Potent WRN inhibitor, Werner syndrome RecQ helicase-IN-3, is orally active with 0.06 µM IC50; exhibits antiproliferative and anticancer effects.Fórmula:C31H30ClF3N8O5Forma y color:SolidPeso molecular:687.07HBV-IN-21
CAS:HBV-IN-21 inhibits HBV DNA replication (IC50: 2.2 μM) and binds HBV capsid protein well (KD: 60.0 μM).Fórmula:C17H17FN4OS2Forma y color:SolidPeso molecular:376.47CB 3717
CAS:CB 3717 is an enzyme inhibitor, antineoplastic agent, folic acid antagonist.Fórmula:C24H23N5O6Forma y color:SolidPeso molecular:477.47Antitumor agent-85
Antitumor agent-85 stabilizes G4-DNA with potent anti-tumor effects.Fórmula:C24H33N7Forma y color:SolidPeso molecular:419.57
