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Proteasa del VIH

Proteasa del VIH

Los inhibidores de la proteasa del VIH son una clase de fármacos antirretrovirales que atacan específicamente la enzima proteasa del virus de la inmunodeficiencia humana (VIH). Al inhibir esta enzima, estos compuestos evitan que el virus procese sus poliproteínas en proteínas maduras y funcionales, bloqueando así la producción de nuevos viriones infecciosos. Los inhibidores de la proteasa del VIH son una piedra angular de la terapia antirretroviral altamente activa (TARGA) utilizada para manejar el VIH/SIDA. En CymitQuimica, ofrecemos una variedad de inhibidores de la proteasa del VIH para apoyar su investigación en el tratamiento del VIH, la resistencia a los medicamentos y la virología.

Se han encontrado 449 productos de "Proteasa del VIH"

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  • HIV-1 inhibitor-31

    CAS:
    <p>HIV-1 inhibitor-31 (compound 4) is a potent inhibitor of HIV-1. HIV-1 inhibitor-31 can be used in the study of AIDS.</p>
    Fórmula:C21H13Cl2N3O2
    Forma y color:Solid
    Peso molecular:410.25
  • Deaminase inhibitor-1

    CAS:
    <p>Deaminase inhibitor-1 is an APOBEC3G DNA Deaminase inhibitor with an IC 50 value of 18.9 μM [1].</p>
    Fórmula:C11H12BrN3OS
    Forma y color:Solid
    Peso molecular:314.2
  • HIV-1 inhibitor-50

    CAS:
    <p>HIV-1 inhibitor-50 is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that targets HIV-1 reverse transcriptase (IC50 = 50 nM).</p>
    Fórmula:C24H18FN5O2
    Forma y color:Solid
    Peso molecular:427.43
  • S-1360

    CAS:
    <p>S-1360 is an inhibitor of HIV-1 integrase.</p>
    Fórmula:C16H12FN3O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:313.28
  • PF-46396

    CAS:
    <p>PF-46396 is a HIV maturation inhibitor and can be used against HIV-1 clade B and C.</p>
    Fórmula:C27H29F3N2O
    Forma y color:Solid
    Peso molecular:454.53
  • HIV-1 inhibitor-39

    CAS:
    <p>HIV-1 inhibitor-39: blocks HIV-1, anti-RT (IC50=15.75 μM), toxic to MT-4 cells (CC50=112.9 μM).</p>
    Fórmula:C20H17ClN4O4S4
    Forma y color:Solid
    Peso molecular:541.09
  • Antiviral agent 9


    <p>Antiviral agent 9: EC50 0.006 nM vs HIV-1, 300x more selective than TAF.</p>
    Fórmula:C38H50N7O8P
    Forma y color:Solid
    Peso molecular:763.82
  • HIV-1 inhibitor-48

    CAS:
    <p>HIV-1 inhibitor-48 is a novel non-nucleoside reverse transcriptase inhibitor (NNRTI) and exhibits anti-HIV-1 activity .</p>
    Fórmula:C19H16BrN5
    Forma y color:Solid
    Peso molecular:394.27
  • HIV-1 inhibitor-35

    CAS:
    <p>HIV-1 inhibitor-35, potent against HIV (EC50: 80 nM LTR, 70 nM CMV), also suppresses HepG2 cells (CC50: 40 nM), may reverse HIV-1 latency.</p>
    Fórmula:C13H12Cl3N5OS
    Forma y color:Solid
    Peso molecular:392.69
  • HIV-1 inhibitor-9

    CAS:
    <p>HIV-1 inhibitor-9 potently blocks WT and NNRTI-resistant HIV strains at low nanomolar levels.</p>
    Fórmula:C24H21N5O
    Forma y color:Solid
    Peso molecular:395.46
  • HIV-1 inhibitor-56

    CAS:
    <p>HIV-1 inhibitor-56 (compound 12126065) is a potent non-nucleoside reverse transcriptase inhibitor with significant antiviral activity against wild-type HIV-1,</p>
    Fórmula:C22H14ClN7O2S
    Forma y color:Solid
    Peso molecular:475.91
  • Cgp 53820

    CAS:
    <p>CGP 53820 is a pseudosymmetric inhibitor of HIV-1 Protease.</p>
    Fórmula:C31H51N5O5
    Forma y color:Solid
    Peso molecular:573.77
  • HIV-1 inhibitor-33

    CAS:
    <p>HIV-1 inhibitor-33, potent against HIV-1 (EC50: 8.6 nM), low toxicity to MT-4 cells (CC50: 18 μM), useful for AIDS research.</p>
    Fórmula:C25H28N6O
    Forma y color:Solid
    Peso molecular:428.53
  • ML67-33

    CAS:
    <p>ML67-33 selectively activates K2P channels; EC50: 36.3 μM (cell-free), 9.7 μM (HEK293). Reversible TREK-1 modulation.</p>
    Fórmula:C18H17Cl2N5
    Pureza:98%
    Forma y color:Solid
    Peso molecular:374.27
  • HEPT

    CAS:
    <p>HEPT is a non-nucleoside inhibitor of HIV-1 reverse transcription.</p>
    Fórmula:C14H16N2O4S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:308.35
  • L-Ristosamine nucleoside

    CAS:
    <p>L-Ristosamine nucleoside shows antiviral activity.</p>
    Fórmula:C21H21N3O7
    Forma y color:Solid
    Peso molecular:427.41
  • Suberosol

    CAS:
    <p>Suberosol possesses anti-HIV replication activity.</p>
    Fórmula:C31H50O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:454.73
  • ZP7

    CAS:
    <p>ZP7 is a HIV-1 replication inhibitor.</p>
    Fórmula:C15H9Br2ClN4OS2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:520.65
  • APA-APA-MPO

    CAS:
    <p>APA-APA-MPO is a PCAF bromodomain/Tat-AcK50 association inhibitor.</p>
    Fórmula:C12H25Cl2N5O
    Pureza:98%
    Forma y color:Solid
    Peso molecular:326.27
  • Ingenol 3-Hexanoate

    CAS:
    <p>Ingenol 3-Hexanoate is a novel potent reactivator of latent HIV-1.</p>
    Fórmula:C26H38O6
    Pureza:98%
    Forma y color:Solid
    Peso molecular:446.58
  • BM 21.1298

    CAS:
    <p>BM 21.1298 is a inhibition of HIV-1 reverse transcriptase.</p>
    Fórmula:C16H13NOS
    Pureza:98%
    Forma y color:Solid
    Peso molecular:267.35
  • D4DAP

    CAS:
    <p>D4DAP is an inhibitor of HIV virus replication.</p>
    Fórmula:C10H12N6O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:248.24
  • Nitrobenzofuroxan

    CAS:
    <p>Nitrobenzofuroxan, is a HIV-1 and IDO1 inhibitor.</p>
    Fórmula:C6H3N3O4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:181.11
  • BMS-663749 lysine

    CAS:
    <p>BMS-663749 lysine is used as a phosphonooxymethyl prodrug 4 for HIV-1 attachment inhibitor.</p>
    Fórmula:C29H39N6O11P
    Pureza:98%
    Forma y color:Solid
    Peso molecular:678.63
  • GSK5750

    CAS:
    <p>GSK5750 is the ribonuclease H activity inhibitor.</p>
    Fórmula:C16H12N4O2S
    Forma y color:Solid
    Peso molecular:324.36
  • 5-Et-ddU

    CAS:
    <p>5-Et-ddU: A pyrimidine nucleoside with anti-HIV-1 activity in human blood cells.</p>
    Fórmula:C11H16N2O4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:240.26
  • L-708906

    CAS:
    <p>L-708906 is the Human Immunodeficiency Virus Type 1 inhibitor.</p>
    Fórmula:C24H20O6
    Pureza:98%
    Forma y color:Solid
    Peso molecular:404.41
  • Dacopafant

    CAS:
    <p>Dacopafant is an antagonist of platlet activationg factor receptor.</p>
    Fórmula:C12H11N3OS
    Forma y color:Solid
    Peso molecular:245.3
  • 5M038

    CAS:
    5M038, a novel inhibitor of HIV envelope-mediated fusion, strongly inhibits gp41-mediated membrane fusion.
    Fórmula:C17H8F6N4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:382.26
  • L 738372

    CAS:
    <p>L 738372 is a non-nucleoside inhibitor of HIV-1 reverse transcriptase.</p>
    Fórmula:C18H15N3O
    Forma y color:Solid
    Peso molecular:289.33
  • Vif-A3G Inhibitor N.41

    CAS:
    <p>Vif-A3G Inhibitor N.41 is a HIV-1 inhibitor-targeting drug. It causes Vif-dependent degradation of human APOBEC3G, thereby inhibiting the Vif-A3G interaction.</p>
    Fórmula:C15H14N2O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:254.28
  • A 75925

    CAS:
    <p>A 75925, a nonnucleoside reverse transcriptase inhibitors (NNRTI), works to inhibit HIV-1 replication.</p>
    Fórmula:C44H54N4O8
    Pureza:98%
    Forma y color:Solid
    Peso molecular:766.92
  • Sp-TTPαS

    CAS:
    Sp-TTPαS is a competitive inhibitor of the catalytic activity of sterile alpha motif and HD domain containing protein 1 (SAMHD1). It competitively inhibits TTP hydrolysis, with a Ki value of 46 µM.
    Fórmula:C10H17N2O13P3S
    Peso molecular:498.23
  • HIV-1 inhibitor-53

    CAS:
    <p>HIV-1 Inhibitor-53 targets HIV-1 protease (IC50: 1.93 nM) and reverse transcriptase (IC50: 2.35 μM), aiding AIDS research.</p>
    Fórmula:C30H34N2O8S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:582.66
  • Fosdevirine

    CAS:
    <p>Fosdevirine (GSK2248761), a non-nucleoside reverse transcriptase (NNRTI) inhibitor with anti-HIV activity, is used in the study of neurological related diseases</p>
    Fórmula:C20H17ClN3O3P
    Pureza:99.92%
    Forma y color:Solid
    Peso molecular:413.79
  • (S)-BI-1001

    CAS:
    <p>(S)-BI-1001 is an active S-enantiomer of BI-1001. (S)-BI-1001 has antiviral potency against HIV-1 integrase (IC50: 28 nM, and EC50: 450 nM and a Kd: 4.7 μM).</p>
    Fórmula:C19H15BrClNO3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:420.68
  • Navuridine

    CAS:
    <p>Navuridine (AZdU) is an oral active inhibitor of HIV reverse transcriptase with a relatively short half-life.</p>
    Fórmula:C9H11N5O4
    Pureza:99.83%
    Forma y color:Solid
    Peso molecular:253.22
  • Isoescin IA

    CAS:
    <p>Isoescin IA is a triterpenoid saponin isolated from the seeds of Aesculus chinensis. It has anti-HIV-1 protease activity.</p>
    Fórmula:C55H86O24
    Pureza:96.00%
    Forma y color:Solid
    Peso molecular:1131.26
  • L 756423

    CAS:
    <p>L756423 is a potent, selective HIV protease inhibitor (Ki=0.049 nM), effective against HIV spread in MT25 lymphocytes at 0.1-0.5 nM, useful for AIDS research.</p>
    Fórmula:C39H48N4O5
    Pureza:99.34% - 99.88%
    Forma y color:Solid
    Peso molecular:652.82
  • Atevirdine

    CAS:
    <p>Atevirdine is an HIV-1 reverse transcriptase inhibitor with antiviral activity for the study of the AIDS dementia complex (ADC).</p>
    Fórmula:C21H25N5O2
    Pureza:98.20%
    Forma y color:Solid
    Peso molecular:379.46
  • GSK-364735

    CAS:
    <p>GSK-364735 is an HIV-1 IN inhibitor.</p>
    Fórmula:C19H18FN3O4
    Pureza:97.73%
    Forma y color:Solid
    Peso molecular:371.36
  • Opaviraline

    CAS:
    <p>Opaviraline (GW-420867X) is a potent reverse transcriptase inhibitor that inhibits Human immunodeficiency virus 1 and has the potential to treat HIV infection.</p>
    Fórmula:C14H17FN2O3
    Pureza:99.94%
    Forma y color:Solid
    Peso molecular:280.29
  • Emivirine

    CAS:
    <p>Emivirine (MKC-442) is a potent and selective nonnucleoside reverse transcriptase inhibitor of human immunodeficiency virus type 1.</p>
    Fórmula:C17H22N2O3
    Pureza:99.8%
    Forma y color:Solid
    Peso molecular:302.37
  • AzddMeC

    CAS:
    <p>AzddMeC (Az-Dcme) is an HIV-1 reverse transcriptase and HIV-1 replication inhibitor with antiretroviral activity.AzddMeC is used in the study of HIV-1 infection</p>
    Fórmula:C10H14N6O3
    Pureza:97.14% - 99.62%
    Forma y color:Solid
    Peso molecular:266.26
  • Lenacapavir

    CAS:
    <p>Lenacapavir (GS-6207) is the first HIV-1 capsid inhibitor approved by the U.S. Food and Drug Administration, the European Medicines Agency, and Health Canada for the treatment of MDR HIV-1 infection.Cost-effective and quality-assured.</p>
    Fórmula:C39H32ClF10N7O5S2
    Pureza:99.61% - 99.87%
    Forma y color:Solid
    Peso molecular:968.28
  • BMS-488043

    CAS:
    <p>BMS-488043 is a novel and unique oral small molecule HIV fusion inhibitor that inhibits the attachment of Human Immunodeficiency Virus type 1 (HIV-1) to CD4(+)</p>
    Fórmula:C22H22N4O5
    Pureza:99.95%
    Forma y color:Solid
    Peso molecular:422.43
  • KM-023

    CAS:
    <p>KM-023 is a new second-generation non-nucleoside reverse transcriptase inhibitor for the study of human immunodeficiency virus (HIV) type 1 infection.</p>
    Fórmula:C18H19N3O3
    Pureza:99.47% - >99.99%
    Forma y color:Solid
    Peso molecular:325.36
  • (2RS)-FPMPA

    CAS:
    <p>(2RS)-FPMPA(FPMPA) has antiviral activity with an IC50 value of 1.85 μM measured in human MT12 cells infected with SHIV (DH4R).</p>
    Fórmula:C9H13FN5O4P
    Pureza:99.9% - >99.99%
    Forma y color:Solid
    Peso molecular:305.2
  • Tenofovir alafenamide fumarate

    CAS:
    <p>Tenofovir alafenamide fumarate (GS-7340) is an oral anti-HIV drug that prevents infection.</p>
    Fórmula:C25H33N6O9P
    Pureza:99.95%
    Forma y color:Solid
    Peso molecular:592.54
  • Suksdorfin

    CAS:
    <p>Suksdorfin has hypoglycemic effects and activates PPARγ, which promotes insulin-dependent glucose uptake by adipocytes and can be used to study obesity .</p>
    Fórmula:C21H24O7
    Pureza:98.54%
    Forma y color:Solid
    Peso molecular:388.41