Proteasa del VIH
Los inhibidores de la proteasa del VIH son una clase de fármacos antirretrovirales que atacan específicamente la enzima proteasa del virus de la inmunodeficiencia humana (VIH). Al inhibir esta enzima, estos compuestos evitan que el virus procese sus poliproteínas en proteínas maduras y funcionales, bloqueando así la producción de nuevos viriones infecciosos. Los inhibidores de la proteasa del VIH son una piedra angular de la terapia antirretroviral altamente activa (TARGA) utilizada para manejar el VIH/SIDA. En CymitQuimica, ofrecemos una variedad de inhibidores de la proteasa del VIH para apoyar su investigación en el tratamiento del VIH, la resistencia a los medicamentos y la virología.
Se han encontrado 477 productos de "Proteasa del VIH"
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NF279
CAS:<p>P2X1 antagonist</p>Fórmula:C49H36N6Na6O23S6Pureza:98%Forma y color:SolidPeso molecular:1407.17VIR-165
VIR-165, a derivative of VIRIP (353-372 of alpha1-antitrypsin), blocks several HIV-1 strains.Fórmula:C109H158N22O25S2Pureza:98%Forma y color:SolidPeso molecular:2240.7Aureothin
CAS:<p>Aureothin: a nitroaryl polyketide with antitumor, antifungal & insecticidal properties; inhibits NADH:oxidoreductase (IC50s: 0.07-22 nmol/mg).</p>Fórmula:C22H23NO6Forma y color:SolidPeso molecular:397.42HIV-IN-9
HIV-IN-9 (Compound 2b) is an HIV inhibitor with an IC50 value of 6.65 μg/mL, demonstrating high binding affinity for HIV-RT.Forma y color:Odour SolidPeptide T
CAS:Peptide T, an HIV-1 derived octapeptide, may inhibit gp120 binding to CD4 and cytokines, and affect VIP receptors.Fórmula:C35H55N9O16Pureza:98%Forma y color:SolidPeso molecular:857.86BNM-III-170
CAS:<p>BNM-III-170 is able to inhibit HIV-1 viral entry into target cells.</p>Fórmula:C25H26ClF7N6O6Forma y color:SolidPeso molecular:674.96AL-470
CAS:AL-470 demonstrates significant antiviral efficacy, exhibiting EC50 values of 0.27 µM against HIV-1, 0.63 µM against HIV-2, and 0.35 µM against EV-A71, asFórmula:C67H57N7O23Forma y color:SolidPeso molecular:1328.2Delavirdine
CAS:<p>Delavirdine, an NNRTI for HIV-1, is used in HAART.</p>Fórmula:C22H28N6O3SForma y color:SolidPeso molecular:456.56Globotriaosylceramides (porcine)
CAS:Globotriaosylceramides, cell membrane glycosphingolipids, act as Shiga toxin receptors and accumulate in Fabry disease, resisting HIV by blocking gp120.Fórmula:C60H113NO18Forma y color:SolidPeso molecular:1136.553Pegaldesleukin
CAS:Pegaldesleukin, a PEG-IL2 conjugate, exhibits antiviral properties, potentially slowing HIV progression, preserving immune function.Forma y color:LiquidEnfuvirtide
CAS:Enfuvirtide (INN) is an HIV fusion inhibitor, the first of a class of antiretroviral drugs used in combination therapy for the treatment of HIV-1 infection.Fórmula:C204H301N51O64Pureza:98%Forma y color:White To Off-White Amorphous SolidPeso molecular:4491.945MPG, HIV related
CAS:MPG: 27-amino acid peptide from HIV-1 gp41 & SV40 T antigen, delivers nucleic acids into cells efficiently.Fórmula:C126H201N35O33SPureza:98%Forma y color:SolidPeso molecular:2766.22GP120, HIV-1 MN
GP120, HIV-1 MN, a peptide, is utilized in researching HIV infection [1] [2].Fórmula:C135H221N45O33Forma y color:SolidPeso molecular:3002.5Clathrin-IN-1
CAS:<p>Pitstop 2 inhibits clathrin-mediated endocytosis, targeting clathrin's terminal domain, with potential in cancer research.</p>Fórmula:C20H13BrN2O3S2Pureza:99.53%Forma y color:SolidPeso molecular:473.36Kni 102
CAS:<p>Kni 102 is a biochemical.</p>Fórmula:C31H41N5O7Forma y color:SolidPeso molecular:595.69Ac-Ser-Gln-Asn-Tyr-Pro-Val-Val-NH2
CAS:Ac-Ser-Gln-Asn-Tyr-Pro-Val-Val-NH2, a peptide substrate for HIV-1 protease, is used in inhibition assays.Fórmula:C38H58N10O12Forma y color:SolidPeso molecular:846.93HIV-1 protease-IN-10
<p>HIV-1 protease-IN-10 (Compound 2), exhibiting HIV-1 latency reversing activity (IC50: 0.22 μM), selectively binds to the PKCδ C1b domain (IC50: 0.69 μM) and</p>Fórmula:C23H40O5Pureza:98%Forma y color:SolidPeso molecular:396.56Tenofovir-C3-O-C15-CF3 ammonium
CAS:Tenofovir-C3-O-C15-CF3 (ammonium) has a longer half-life and stronger anti-HIV action, improving pharmacokinetics in vivo.Fórmula:C28H52F3N6O5PForma y color:SolidPeso molecular:640.73HIV-1 inhibitor-75
HIV-1inhibitor-75 is a human immunodeficiency virus 1 (HIV-1) inhibitor with an EC50 range of 0.0039-0.338 μM. Its target is the reverse transcriptase, exhibiting an IC50 value of 0.055 μM. Additionally, HIV-1inhibitor-75 demonstrates good metabolic stability in vitro, presenting moderate clearance rates and an extended half-life in human plasma and liver microsomes.Fórmula:C25H20ClN3O3SForma y color:SolidPeso molecular:477.96NNRT-IN-9
NNRT-IN-9 (Compound EG28) is a non-nucleoside reverse transcriptase inhibitor (NNRT). It demonstrates strong antiviral and resistance-fighting activity against wild-type (WT) and various clinically relevant mutant strains (E138K and K103N + Y181C) of HIV-1, with EC50 values of 55 nM, 67 nM, and 3910 nM, respectively. NNRT-IN-9 is applicable in acquired immunodeficiency syndrome (AIDS) research.Forma y color:Odour Solid
