gsk-3
Los inhibidores de GSK-3 son compuestos que inhiben la Glicógeno Sintasa Quinasa 3 (GSK-3), una enzima involucrada en numerosos procesos celulares, como el metabolismo del glucógeno, la transcripción génica y la proliferación celular. GSK-3 está implicada en diversas enfermedades, como la diabetes, los trastornos neurodegenerativos y el cáncer. Los inhibidores de GSK-3 son herramientas importantes para explorar estas vías y desarrollar posibles terapias. En CymitQuimica, ofrecemos inhibidores de GSK-3 para apoyar su investigación en enfermedades metabólicas, neurobiología y oncología.
Se han encontrado 107 productos para "gsk-3".
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GSK-3β inhibitor 14
CAS:GSK-3β inhibitor 14 (1,5-Benzothiazepin-4(5H)-one, 2,3-dihydro-2-methyl-5-(phenylmethyl)-) is a weak GSK-3β inhibitor, IC50﹥ 100μM.Fórmula:C17H17NOSPureza:99.97%Forma y color:SolidPeso molecular:283.39GSK3β Inhibitor XI
CAS:GSK3β Inhibitor XI has GSK3β inhibitory effect.Fórmula:C18H15N5O3Forma y color:SolidPeso molecular:349.35Phospho-Glycogen Synthase Peptide-2(substrate)
CAS:Phospho-Glycogen Synthase Peptide-2 is a GSK-3 substrate, useful for serine kinase affinity purification.Fórmula:C123H191N40O48PForma y color:SolidPeso molecular:3029.087MeBIO
CAS:MeBIO is an agonist of aryl hydrocarbon receptor, with IC50 of 44 and 55 μM for GSK-3 and CDK1/CyclinB, respectively. MeBIO does not affect GSK-3β.Fórmula:C17H12BrN3O2Pureza:99.64%Forma y color:SolidPeso molecular:370.2Ref: TM-T21966
1mg37,00€5mg71,00€1mL*10mM (DMSO)81,00€10mg111,00€25mg208,00€50mg335,00€100mg492,00€500mg1.071,00€Kinase Inhibitor Library
A unique collection of xnum kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases;Forma y color:Odour SolidRef: TM-L1600
1mgA consultar10μL*10mM (DMSO)A consultar30μL*10mM (DMSO)A consultar50μL*10mM (DMSO)A consultar100μL*10mM (DMSO)A consultaryGsy2p-IN-H23
CAS:yGsy2p-IN-H23 targets yeast GSY2 with IC50 of 875μM for hGYS1, for GSD research.Fórmula:C23H27N3O2Forma y color:SolidPeso molecular:377.488VP3.15 dihydrobromide
CAS:VP3.15 dihydrobromide: potent, oral, CNS-penetrant PDE7/GSK3 inhibitor; IC50s: PDE7- 1.59 μM, GSK- 0.88 μM.Fórmula:C20H24Br2N4OSPureza:99.67% - ≥95%Forma y color:SolidPeso molecular:528.3IM-12
CAS:IM-12, an effective GSK-3β inhibitor(IC50=53 nM), regulates Wnt signalling.Fórmula:C22H20FN3O2Pureza:99.42% - >99.99%Forma y color:Orange SolidPeso molecular:377.41Ref: TM-T2261
500mgA consultar2mg34,00€5mg50,00€1mL*10mM (DMSO)55,00€10mg82,00€25mg146,00€50mg222,00€100mg334,00€Indirubin-3′-oxime
CAS:Indirubin-3′-oxime is an effective inhibitor of cyclin-dependent protein kinases, and may play an obligate role in neuronal apoptosis in Alzheimer's disease.Fórmula:C16H11N3O2Pureza:98.34%Forma y color:SolidPeso molecular:277.28Ref: TM-T9138
1mg44,00€1mL*10mM (DMSO)92,00€5mg93,00€10mg120,00€25mg236,00€50mg356,00€100mg532,00€200mg772,00€Indirubin-3'-monoxime
CAS:Indirubin-3'-monoxime (Indirubin-3'-oxime) is a potent inhibitor of GSK3β (IC50: 22 nM) and also inhibits CDKs ( (IC50s: 100/180/250 nM for Cdk5/p35, Cdk1/Fórmula:C16H11N3O2Pureza:99.55%Forma y color:Red SolidPeso molecular:277.28GSK-3β inhibitor 10
CAS:GSK-3β inhibitor 10 has skin-whitening, anti-oxidizing and PPAR activities.Fórmula:C12H12N2O3SPureza:98.06%Forma y color:SolidPeso molecular:264.3CP21R7
CAS:CP21 is a specific GSK3β inhibitor, used to activate stem cells for differentiation, often paired with BMP4 for mesodermal fate.Fórmula:C19H15N3O2Pureza:96.14% - 99.16%Forma y color:SolidPeso molecular:317.34Ref: TM-T3684
1mg38,00€2mg50,00€1mL*10mM (DMSO)77,00€5mg84,00€10mg120,00€25mg236,00€50mg356,00€100mg537,00€CHIR-99021
CAS:View and buy CHIR-99021 from TargetMol.CHIR-99021 is a GSK-3α/β inhibitor.Cited in 10 publications.Fórmula:C22H18Cl2N8Pureza:97.94% - ≥95%Forma y color:White SolidPeso molecular:465.34Ref: TM-T2310
2mg40,00€5mg60,00€1mL*10mM (DMSO)62,00€10mg92,00€25mg152,00€50mg240,00€100mg384,00€200mg572,00€500mg888,00€Tideglusib
CAS:Tideglusib (NP031112), a non-ATP competitive inhibitor of glycogen synthase kinase 3 (GSK-3), is with anti-inflammatory and neuroprotective activities.Fórmula:C19H14N2O2SPureza:98.40% - 99.35%Forma y color:SolidPeso molecular:334.39Ref: TM-T3067
1mL*10mM (DMSO)33,00€10mg44,00€25mg73,00€50mg107,00€100mg177,00€200mg268,00€500mg465,00€RGB-286638 free base
CAS:RGB-286638 free base inhibits CDKs (1-5 nM), weaker on CDK7/6.Fórmula:C29H35N7O4Pureza:95.67% - 99.91%Forma y color:SolidPeso molecular:545.63SB 216763
CAS:SB 216763 (SB216763) is an effective and specific GSK-3α/β inhibitor (IC50: 34.3 nM).Fórmula:C19H12Cl2N2O2Pureza:98.89% - 99.13%Forma y color:SolidPeso molecular:371.22Ref: TM-T3077
2mg37,00€5mg50,00€1mL*10mM (DMSO)50,00€10mg74,00€25mg124,00€50mg187,00€100mg315,00€500mg762,00€BIO-acetoxime
CAS:BIO-acetoxime (GSK-3 Inhibitor X) is a potent dual GSK3α/β inhibitor with IC50 of 10 nM, >240-fold selectivity over CDK5/p25, CDK2/cyclin A and CDK1/cyclin B.Fórmula:C18H12BrN3O3Pureza:97.15%Forma y color:SolidPeso molecular:398.21Ref: TM-T6787
1mg34,00€2mg46,00€5mg66,00€1mL*10mM (DMSO)73,00€10mg99,00€25mg177,00€50mg281,00€100mg439,00€AZD2858
CAS:AZD2858 is a selective GSK-3 inhibitor, inhibiting tau phosphorylation at the S396 site and activating Wnt signaling pathway.Fórmula:C21H23N7O3SPureza:99.25% - 99.36%Forma y color:SolidPeso molecular:453.52Bikinin
CAS:Bikinin (Abrasin), a potent inhibitor of plant GSK-3/Shaggy-like kinase, activates BR signaling downstream of the BR receptor.Fórmula:C9H9BrN2O3Pureza:99.86% - >99.99%Forma y color:SolidPeso molecular:273.083Ref: TM-T1965
1mL*10mM (DMSO)33,00€10mg44,00€25mg73,00€50mg113,00€100mg177,00€200mg264,00€500mg447,00€LY2090314
CAS:LY2090314, a potent GSK-3α/β blocker (IC50: 1.5/0.9 nM), could boost platinum chemo. Tested in leukemia and advanced cancers.Fórmula:C28H25FN6O3Pureza:99.21% - 99.91%Forma y color:SolidPeso molecular:512.53Ref: TM-T1755
1mg34,00€2mg50,00€5mg90,00€1mL*10mM (DMSO)92,00€10mg131,00€25mg225,00€50mg369,00€100mg545,00€200mg777,00€
