gsk-3
Los inhibidores de GSK-3 son compuestos que inhiben la Glicógeno Sintasa Quinasa 3 (GSK-3), una enzima involucrada en numerosos procesos celulares, como el metabolismo del glucógeno, la transcripción génica y la proliferación celular. GSK-3 está implicada en diversas enfermedades, como la diabetes, los trastornos neurodegenerativos y el cáncer. Los inhibidores de GSK-3 son herramientas importantes para explorar estas vías y desarrollar posibles terapias. En CymitQuimica, ofrecemos inhibidores de GSK-3 para apoyar su investigación en enfermedades metabólicas, neurobiología y oncología.
Se han encontrado 107 productos para "gsk-3".
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SB 216763
CAS:SB 216763 (SB216763) is an effective and specific GSK-3α/β inhibitor (IC50: 34.3 nM).Fórmula:C19H12Cl2N2O2Pureza:98.89% - 99.13%Forma y color:SolidPeso molecular:371.22Ref: TM-T3077
2mg37,00€5mg50,00€1mL*10mM (DMSO)50,00€10mg74,00€25mg124,00€50mg187,00€100mg315,00€500mg762,00€CP21R7
CAS:CP21 is a specific GSK3β inhibitor, used to activate stem cells for differentiation, often paired with BMP4 for mesodermal fate.Fórmula:C19H15N3O2Pureza:96.14% - 99.16%Forma y color:SolidPeso molecular:317.34Ref: TM-T3684
1mg38,00€2mg50,00€1mL*10mM (DMSO)77,00€5mg84,00€10mg120,00€25mg236,00€50mg356,00€100mg537,00€GSK3i XIII
CAS:GSK3i XIII (GSK3 inhibitor XIII) is a GSK-3 ATP-binding site inhibitor.Fórmula:C18H19N5Pureza:99.46%Forma y color:SolidPeso molecular:305.38Ref: TM-T24111
1mg50,00€5mg101,00€1mL*10mM (DMSO)111,00€10mg150,00€25mg241,00€50mg353,00€100mg572,00€TWS119
CAS:TWS119 is a GSK-3β inhibitor; capable of inducing neuronal differentiationFórmula:C18H14N4O2Pureza:98.14% - 99.63%Forma y color:SolidPeso molecular:318.33GSK 3 Inhibitor IX
CAS:GSK 3 Inhibitor IX (6-BIO) is a selective reversible, ATP-competitive inhibitor of GSK-3α/β and CDK1-cyclinB complex.Fórmula:C16H10BrN3O2Pureza:98% - 99.72%Forma y color:SolidPeso molecular:356.17Ref: TM-T1917
1mg42,00€2mg52,00€5mg78,00€1mL*10mM (DMSO)86,00€10mg96,00€25mg216,00€50mg389,00€100mg577,00€500mg1.234,00€VP3.15 dihydrobromide
CAS:VP3.15 dihydrobromide: potent, oral, CNS-penetrant PDE7/GSK3 inhibitor; IC50s: PDE7- 1.59 μM, GSK- 0.88 μM.Fórmula:C20H24Br2N4OSPureza:99.67% - ≥95%Forma y color:SolidPeso molecular:528.3PF-04802367
CAS:PF-04802367 is a highly selective GSK-3 inhibitor with an IC50 of 2.1 nM based on a recombinant human GSK-3β enzyme assay and 1.1 nM based on ADP-Glo assay.Fórmula:C16H16ClN5O3Pureza:98.76%Forma y color:SolidPeso molecular:361.78Ref: TM-T9611
1mg49,00€5mg100,00€1mL*10mM (DMSO)111,00€10mg152,00€25mg264,00€50mg399,00€100mg532,00€200mg705,00€5-Bromoindole
CAS:5-bromoindole is a potential inhibitor of glycogen synthase kinase 3 (GSK-3)and an important pharmaceutical chemical intermediateFórmula:C8H6BrNPureza:99.99%Forma y color:SolidPeso molecular:196.04R547
CAS:R547 (Ro 4584820) is a potent ATP-competitive inhibitor of CDK1/2/4 with Ki of 2 nM/3 nM/1 nM.Fórmula:C18H21F2N5O4SPureza:90% - 99.64%Forma y color:SolidPeso molecular:441.45Ref: TM-T6312
1mg48,00€5mg96,00€1mL*10mM (DMSO)114,00€10mg140,00€25mg254,00€50mg487,00€100mg700,00€200mg973,00€Bisindolylmaleimide I
CAS:Bisindolylmaleimide I (GF109203X) is a potent and highly selective protein kinase C (PKC) inhibitor with a Ki of 14 nM.Fórmula:C25H24N4O2Pureza:97.51% - 98.75%Forma y color:Orange SolidPeso molecular:412.48AR-A014418
CAS:AR-A014418 (GSK 3β inhibitor VIII) is an ATP-competitive, and selective GSK3β inhibitor.Fórmula:C12H12N4O4SPureza:99.97% - ≥95%Forma y color:Yellow SolidPeso molecular:308.31CHIR-99021
CAS:View and buy CHIR-99021 from TargetMol.CHIR-99021 is a GSK-3α/β inhibitor.Cited in 10 publications.Fórmula:C22H18Cl2N8Pureza:97.94% - ≥95%Forma y color:White SolidPeso molecular:465.34Ref: TM-T2310
2mg40,00€5mg60,00€1mL*10mM (DMSO)62,00€10mg92,00€25mg152,00€50mg240,00€100mg384,00€200mg572,00€500mg888,00€Indirubin-3′-oxime
CAS:Indirubin-3′-oxime is an effective inhibitor of cyclin-dependent protein kinases, and may play an obligate role in neuronal apoptosis in Alzheimer's disease.Fórmula:C16H11N3O2Pureza:98.34%Forma y color:SolidPeso molecular:277.28Ref: TM-T9138
1mg44,00€1mL*10mM (DMSO)92,00€5mg93,00€10mg120,00€25mg236,00€50mg356,00€100mg532,00€200mg772,00€Indirubin-3'-monoxime
CAS:Indirubin-3'-monoxime (Indirubin-3'-oxime) is a potent inhibitor of GSK3β (IC50: 22 nM) and also inhibits CDKs ( (IC50s: 100/180/250 nM for Cdk5/p35, Cdk1/Fórmula:C16H11N3O2Pureza:99.55%Forma y color:Red SolidPeso molecular:277.28AZD2858
CAS:AZD2858 is a selective GSK-3 inhibitor, inhibiting tau phosphorylation at the S396 site and activating Wnt signaling pathway.Fórmula:C21H23N7O3SPureza:99.25% - 99.36%Forma y color:SolidPeso molecular:453.52ALSTERPAULLONE
CAS:Alsterpaullone is a Cyclin-Dependent Kinase Inhibitor, Mediated Toxicity in HeLa Cells Through Apoptosis-Inducing EffecFórmula:C16H11N3O3Pureza:99.8%Forma y color:SolidPeso molecular:293.28Ref: TM-T7426
1mg55,00€1mL*10mM (DMSO)105,00€5mg110,00€10mg173,00€25mg296,00€50mg424,00€100mg587,00€200mg792,00€AZD1080
CAS:AZD1080 is a selective, orally active, brain permeable GSK3 inhibitor.Fórmula:C19H18N4O2Pureza:97.72% - 99.75%Forma y color:Yellow SolidPeso molecular:334.37Ref: TM-T1741
1mg40,00€2mg52,00€1mL*10mM (DMSO)59,00€5mg80,00€10mg117,00€25mg207,00€50mg333,00€100mg406,00€KenPaullone
CAS:KenPaullone (9-Bromopaullone), a potent CDK1, CDK2 and CDK5 inhibitor, as new enhancer for iTreg cell differentiation.Fórmula:C16H11BrN2OPureza:97.14% - 98.99%Forma y color:SolidPeso molecular:327.18Ref: TM-T2247
1mg35,00€2mg50,00€5mg66,00€1mL*10mM (DMSO)71,00€10mg89,00€25mg178,00€50mg303,00€100mg449,00€500mg1.018,00€GS87
CAS:GS87 is a highly specific inhibitor of GSK3 (glycogen synthase kinase 3) that induces extensive differentiation of AML cells.Fórmula:C16H11N5O2SPureza:98.86%Forma y color:White SolidPeso molecular:337.36CHIR-98014
CAS:CHIR-98014 (CT98014) is a selective GSK3 inhibitor; potentiate insulin activation of glucose transport and utilization in vitro and in vivo.Fórmula:C20H17Cl2N9O2Pureza:97.25% - 99.59%Forma y color:SolidPeso molecular:486.31Ref: TM-T2608
5mg71,00€1mL*10mM (DMSO)75,00€10mg102,00€25mg205,00€50mg334,00€100mg537,00€500mg1.134,00€
