PI3K
Los inhibidores de PI3K son compuestos que bloquean la actividad de las fosfoinosítido 3-quinasas (PI3Ks), una familia de enzimas involucradas en una amplia gama de procesos celulares, incluidos el crecimiento, la proliferación, la supervivencia y el metabolismo. La vía PI3K/Akt/mTOR a menudo está desregulada en el cáncer, lo que convierte a PI3K en un objetivo clave para la terapia contra el cáncer. Los inhibidores de PI3K son herramientas fundamentales para estudiar la transducción de señales, la biología del cáncer y el desarrollo de terapias dirigidas. En CymitQuimica, ofrecemos una variedad de inhibidores de PI3K para apoyar su investigación en señalización celular, oncología y desarrollo terapéutico.
Se han encontrado 231 productos de "PI3K"
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ETP-46321
CAS:ETP-46321 is an effective and orally bioavailable PI3Kα/PI3Kδ inhibitor (Ki: 2.3/14.2 nM).Fórmula:C20H27N9O3SPureza:99.8%Forma y color:SolidPeso molecular:473.55Ref: TM-TQ0229
1mg39,00€5mg87,00€10mg123,00€25mg225,00€50mg314,00€100mg430,00€200mg582,00€1mL*10mM (DMSO)90,00€Autophinib
CAS:Autophinib is a potent autophagy inhibitor with a novel chemotype with IC50 values of 90 and 40 nM for autophagy in starvation induced autophagy assay andFórmula:C14H11ClN6O3Pureza:99.25% - 99.41%Forma y color:SolidPeso molecular:346.73Ref: TM-T4219
2mg39,00€5mg58,00€10mg88,00€25mg160,00€50mg215,00€100mg334,00€200mg494,00€1mL*10mM (DMSO)66,00€Taselisib
CAS:Taselisib (GDC-0032) is an oral PI3K alpha inhibitor with potential cancer-treating properties.Fórmula:C24H28N8O2Pureza:99.62% - 99.79%Forma y color:SolidPeso molecular:460.53Ref: TM-T1999
2mg46,00€5mg66,00€10mg92,00€25mg157,00€50mg197,00€100mg350,00€200mg522,00€500mg840,00€1mL*10mM (DMSO)66,00€IITZ-01
CAS:IITZ-01 is potent autophagy inhibitor with single-agent anticancer activity ( IC50 of 2.62 μM for PI3Kγ.)Fórmula:C26H23FN8OPureza:99.31%Forma y color:SolidPeso molecular:482.51Lupiwighteone
CAS:Lupiwighteone has anti-angiogenesis potential, it also has anticancer and cancer preventive effects on SH-SY5Y cells.Fórmula:C20H18O5Pureza:98.92%Forma y color:SolidPeso molecular:338.35Leniolisib
CAS:Leniolisib (CDZ173) (CDZ173) is a potent and selective PI3Kδ inhibitor (IC50: 11 nM).
Fórmula:C21H25F3N6O2Pureza:99.88%Forma y color:SolidPeso molecular:450.46Arnicolide D
CAS:Arnicolide D is a sesquiterpene lactone.Fórmula:C19H24O5Pureza:96.66% - 99.93%Forma y color:SolidPeso molecular:332.39BGT226
CAS:BGT226 (NVP-BGT226) is a novel dual PI3K / mTOR inhibitor, it acts on PI3K α/β/γ with IC50 of 4 nM / 63 nM / 38 nM, respectively.Fórmula:C28H25F3N6O2Pureza:95.74% - 99.78%Forma y color:SolidPeso molecular:534.53Ref: TM-T6072L
1mg49,00€2mg65,00€5mg97,00€10mg156,00€25mg311,00€50mg512,00€100mg777,00€1mL*10mM (DMSO)113,00€Heterophyllin B
CAS:Heterophyllin B hinders esophageal cancer cell adhesion/invasion via PI3K/AKT/β-catenin and gene regulation.Fórmula:C40H58N8O8Pureza:99.12% - 99.85%Forma y color:SolidPeso molecular:778.94AMG319
CAS:AMG319 is a potent and selective PI3Kδ inhibitor with IC50 of 18 nM, >47-fold selectivity over other PI3Ks. Phase 2.Fórmula:C21H16FN7Pureza:98.9% - 99.24%Forma y color:Crystalline SolidPeso molecular:385.4P7C3-A20
CAS:P7C3-A20 is a derivative of P7C3 that has proneurogenic and neuroprotective activity.Fórmula:C22H19Br2FN2OPureza:96.83% - ≥98%Forma y color:SolidPeso molecular:506.21Voxtalisib
CAS:Voxtalisib (XL765) (SAR245409, XL765) is a dual inhibitor of mTOR/PI3K, mostly for p110γ with IC50 of 9 nM; also inhibits DNA-PK and mTOR. Phase 1/2.Fórmula:C13H14N6OPureza:98.21% - 99.69%Forma y color:SolidPeso molecular:270.29Ref: TM-T7014
1mg38,00€2mg49,00€5mg79,00€10mg124,00€25mg240,00€50mg384,00€100mg560,00€1mL*10mM (DMSO)79,00€Umbralisib
CAS:Umbralisib (TGR 1202) is a PI3Kδ inhibitor.Fórmula:C31H24F3N5O3Pureza:99.56% - 99.56%Forma y color:White SolidPeso molecular:571.55Ref: TM-T4976
1mg48,00€2mg65,00€5mg96,00€10mg170,00€25mg343,00€50mg449,00€100mg658,00€1mL*10mM (DMSO)120,00€AZD-8835
CAS:AZD-8835 is a mixed inhibitor of PI3Kα/δ (IC50: 6.2/5.7 nM), also with selectivity against PI3Kβ/γ (IC50: 431/90 nM).Fórmula:C22H31N9O3Pureza:98.22% - 99.88%Forma y color:SolidPeso molecular:469.54AS-604850
CAS:AS-604850: ATP-competitive PI3Kγ inhibitor, IC50 250 nM, 18x > PI3Kα, 80x > PI3Kδ/β.Fórmula:C11H5F2NO4SPureza:99.65%Forma y color:SolidPeso molecular:285.22PIK-93
CAS:PIK-93 is the first potent, synthetic PI4K inhibitor with IC50 of 19 nM; inhibits PI3Kα with IC50 of 39 nM.Fórmula:C14H16ClN3O4S2Pureza:97.72%Forma y color:SolidPeso molecular:389.88Ref: TM-T2616
1mg44,00€5mg89,00€10mg111,00€25mg210,00€50mg323,00€100mg452,00€200mg647,00€1mL*10mM (DMSO)88,00€CH5132799
CAS:CH5132799 has been used in trials studying the treatment of Solid Tumors.Fórmula:C15H19N7O3SPureza:99.41% - 99.87%Forma y color:SolidPeso molecular:377.42Ref: TM-T2619
1mg64,00€2mg96,00€5mg144,00€10mg227,00€25mg420,00€50mg622,00€100mg885,00€500mg1.786,00€Seletalisib
CAS:Seletalisib (UCB5857) (UCB5857) is a potent and specific PI3Kδ inhibitor (IC50: 12 nM).Fórmula:C23H14ClF3N6OPureza:99.81%Forma y color:SolidPeso molecular:482.85Ref: TM-TQ0044
1mg54,00€2mg77,00€5mg114,00€10mg178,00€25mg313,00€50mg447,00€100mg625,00€1mL*10mM (DMSO)119,00€α-Linolenic acid
CAS:α-Linolenic Acid (ALA) is an essential fatty acid. α-Linolenic acid improves memory, inhibits thrombosis, and lowers blood lipids. Cost-effective and quality-assured.Fórmula:C18H30O2Pureza:97.05% - 99.81%Forma y color:Physical Description Clear Colorless Liquid (Ntp 1992)Peso molecular:278.43GSK2636771
CAS:GSK2636771, an effective, specific, orally bioavailable, PI3Kβ inhibitor, has been used in cancer, lymphoma, solid neoplasm, recurrent solid neoplasm, and
Fórmula:C22H22F3N3O3Pureza:98.58% - ≥95%Forma y color:SolidPeso molecular:433.42Vps34-IN-1
CAS:Vps34-IN-1: potent, selective Vps34 inhibitor, 25 nM IC50, spares class I/II PI3Ks.Fórmula:C21H24ClN7OPureza:97.04%Forma y color:SolidPeso molecular:425.91Ref: TM-T7015
1mg46,00€2mg59,00€5mg93,00€10mg131,00€25mg219,00€50mg350,00€100mg505,00€1mL*10mM (DMSO)92,00€SAR405
CAS:SAR-405 inhibits PIK3C3/Vps34 (IC50: 1.2 nM, Kd: 1.5 nM), blocks autophagy, and enhances MTOR inhibitor effects on cancer cells.Fórmula:C19H21ClF3N5O2Pureza:99.42% - 99.79%Forma y color:SolidPeso molecular:443.85PIK-90
CAS:PIK-90, a DNA-PK and PI3K inhibitor, suppresses p110α( IC50=11 nM), p110γ(IC50=18 nM) and DNA-PK(IC50=13 nM) .
Fórmula:C18H17N5O3Pureza:98.25% - ≥95%Forma y color:SolidPeso molecular:351.36A66
CAS:A66 is a specific and effective p110α inhibitor(IC50=32 nM).Fórmula:C17H23N5O2S2Pureza:99.51% - ≥95%Forma y color:SolidPeso molecular:393.53Ref: TM-T2418
2mg34,00€5mg52,00€10mg79,00€25mg137,00€50mg234,00€100mg344,00€200mg485,00€1mL*10mM (DMSO)52,00€Linperlisib
CAS:Linperlisib (PI3Kδ-IN-2) is a potent and selective inhibitor of PI3KδFórmula:C28H37FN6O5SPureza:99.01%Forma y color:SolidPeso molecular:588.69Ref: TM-T6330
1mg34,00€2mg46,00€5mg66,00€10mg90,00€25mg192,00€50mg295,00€100mg462,00€1mL*10mM (DMSO)87,00€Vps34-IN-4
CAS:VPS34 inhibitor 1 (Compound 19, PIK-III analogue) (PIK-III analogue) is a potent and selective inhibitor of VPS34( IC50 : 15 nM)Fórmula:C21H25N7OPureza:98.6%Forma y color:SolidPeso molecular:391.47Ref: TM-T7944
1mg66,00€5mg144,00€10mg227,00€25mg399,00€50mg567,00€100mg753,00€200mg1.035,00€1mL*10mM (DMSO)159,00€CAY10505
CAS:CAY10505, a form of dehydroxyl of AS-252424, is a PI3Kγ inhibitor (IC50: 33 nM).Fórmula:C14H8FNO3SPureza:99.69% - 99.74%Forma y color:SolidPeso molecular:289.28Ref: TM-T6433
10mg35,00€25mg56,00€50mg92,00€100mg153,00€200mg216,00€500mg369,00€1mL*10mM (DMSO)40,00€GDC-0326
CAS:GDC-0326 is a potent and selective inhibitor of α-Isoform of Phosphoinositide 3-Kinase (PI3Kalpha inhibitor).Fórmula:C19H22N6O3Pureza:99.35% - >99.99%Forma y color:SolidPeso molecular:382.42Ref: TM-T3985
1mg35,00€2mg49,00€5mg95,00€10mg155,00€25mg255,00€50mg406,00€100mg592,00€1mL*10mM (DMSO)94,00€AZD8186
CAS:AZD8186 is an effective and specific PI3Kβ/δ inhibitor (IC50: 4/12 nM).Fórmula:C24H25F2N3O4Pureza:99.89% - 99.91%Forma y color:SolidPeso molecular:457.47Ref: TM-T6773
2mg46,00€5mg66,00€10mg99,00€25mg168,00€50mg304,00€100mg505,00€500mg1.121,00€1mL*10mM (DMSO)72,00€Selective PI3Kδ Inhibitor 1
CAS:Selective PI3Kδ Inhibitor 1 is a PI3Kδ Inhibitor( IC50 = 0.9 nM).Fórmula:C23H20FN7OPureza:97.96%Forma y color:SolidPeso molecular:429.45Pilaralisib analogue
CAS:Pilaralisib analogue (XL147 analogue) is a selective and reversible class I PI3K inhibitor for PI3Kα/δ/γ.Fórmula:C21H16N6O2S2Pureza:99.3% - 99.72%Forma y color:SolidPeso molecular:448.52Ref: TM-T2377
2mg38,00€5mg55,00€10mg88,00€25mg139,00€50mg216,00€100mg374,00€200mg485,00€1mL*10mM (DMSO)87,00€AZD 6482
CAS:AZD 6482 (KIN-193) is a potent and selective inhibitor of p110β and PI3Kβ with IC50 values of 0.69nM and 10nM.Cost-effective and quality-assured.Fórmula:C22H24N4O4Pureza:99.87% - 99.95%Forma y color:SolidPeso molecular:408.45PIK-293
CAS:PIK-293 is a PI3K inhibitor, for PI3Kδ( IC50=0.24 μM), and less potent for PI3Kα/β/ γ.Fórmula:C22H19N7OPureza:99.88%Forma y color:SolidPeso molecular:397.43Ref: TM-T3348
1mg46,00€2mg62,00€5mg90,00€10mg144,00€25mg260,00€50mg394,00€100mg572,00€1mL*10mM (DMSO)100,00€ETP-45658
CAS:ETP-45658 (ETP45658) is a PI 3-kinase inhibitor (IC50 values are 22, 30, 129 and 710 nM for PI 3-Kα, PI 3-Kδ, PI 3-Kβ and PI 3-Kγ respectively).Fórmula:C16H17N5O2Pureza:99.14%Forma y color:SolidPeso molecular:311.34Ref: TM-T25399
1mg52,00€5mg111,00€10mg175,00€25mg316,00€50mg512,00€100mg747,00€1mL*10mM (DMSO)124,00€Dactolisib
CAS:Dactolisib (BEZ235) is an orally bioavailable inhibitor of PI3K and mTOR (IC50s: 4 nM/5 nM/7 nM/75 nM, and 20.7 nM for p110α/p110γ/p110δ/p110β and mTOR).
Fórmula:C30H23N5OPureza:97.64% - 99.85%Forma y color:SolidPeso molecular:469.54Pectolinarin
CAS:Pectolinarin is a Cirsium isolate with anti-inflammatory activity.Fórmula:C29H34O15Pureza:98% - 99.79%Forma y color:SolidPeso molecular:622.57MTX-211
CAS:MTX-211, an inhibitor of EGFR and PI3K, is used for the therapy of cancer and other diseases.Fórmula:C20H14Cl2FN5O2SPureza:97.6% - >99.99%Forma y color:SolidPeso molecular:478.33Ref: TM-T4296
1mg64,00€2mg95,00€5mg170,00€10mg274,00€25mg464,00€50mg640,00€100mg847,00€200mg1.159,00€1mL*10mM (DMSO)180,00€Pictilisib
CAS:Pictilisib (GDC-0941) (GDC-0941) is a potent pan inhibitor of class I catalytic subunits of PI3K (IC50s: 3/33/3/75 nM for p110α/β/δ/γ).Fórmula:C23H27N7O3S2Pureza:98.69% - 99.97%Forma y color:SolidPeso molecular:513.64Sincalide
CAS:Sincalide (CCK-8) is an injectable drug used to diagnose gallbladder and pancreas disorders; it's a cholecystokinin fragment.Fórmula:C49H62N10O16S3Pureza:98.32%Forma y color:SolidPeso molecular:1143.27IC-87114
CAS:IC-87114 is a specific PI3Kδ inhibitor(IC50=0.5 μM).Fórmula:C22H19N7OPureza:99.30% - >99.99%Forma y color:SolidPeso molecular:397.43Orobol
CAS:Orobol (3’,4’,5,7-tetrahydroxy-isoflavon) is an inhibitor of tyrosine-specific protein kinase and phosphatidylinositol turnover.Fórmula:C15H10O6Pureza:98% - 98%Forma y color:SolidPeso molecular:286.24Musk ketone
CAS:Musk ketone may suppress cancer cell growth, induce apoptosis, and boost glutathione S-transferase, potentially aiding cancer protection.Fórmula:C14H18N2O5Pureza:99.85%Forma y color:Yellow Crystals Physical Description Light Yellow Crystalline Solid Insoluble In Water (Ntp 1992)Peso molecular:294.30AS-041164
CAS:AS-041164: Oral PI3Kγ inhibitor, IC50 70 nM; weaker on PI3Kα/β/δ; anti-inflammatory.Fórmula:C11H7NO4SPureza:99.45%Forma y color:SolidPeso molecular:249.24PQR530
CAS:PQR530, a potent dual PI3K/mTORC1/2 inhibitor, blocks PKB and pS6 phosphorylation (IC50: 0.07 μM) and has antitumor properties.Fórmula:C18H23F2N7O2Pureza:99.5%Forma y color:SolidPeso molecular:407.42YM-201636
CAS:YM201636 (IC50=33 nM), a specific PIKfyve inhibitor, is less effective to p110α and insensitive to Fabl, which is yeast orthologue.Fórmula:C25H21N7O3Pureza:93.28% - 98.3%Forma y color:SolidPeso molecular:467.48Ref: TM-T6110
1mg46,00€2mg60,00€5mg90,00€10mg170,00€25mg340,00€50mg532,00€100mg760,00€500mg1.558,00€1mL*10mM (DMSO)92,00€Polygalasaponin F
CAS:Polygalasaponin F reduces neuroinflammation, blocks TNF-α/NO, and protects neurons by modulating NF-kB and NMDAR pathways.Fórmula:C53H86O23Pureza:98% - 99.83%Forma y color:SolidPeso molecular:1091.24Isorhamnetin
CAS:Isorhamnetin (3-methylquercetin) is the methylated metabolite of quercetin.
Fórmula:C16H12O7Pureza:99.20% - >99.99%Forma y color:SolidPeso molecular:316.26Pilaralisib
CAS:Pilaralisib (XL-147) is an orally available small molecule that selectively inhibits the activity of phosphoinositide-3 kinase (PI3K).
Fórmula:C25H25ClN6O4SPureza:98.51% - 99.61%Forma y color:SolidPeso molecular:541.02SF2523
CAS:SF2523 is a highly selective and potent inhibitor.Fórmula:C19H17NO5SPureza:99.1% - 99.51%Forma y color:SolidPeso molecular:371.41Ref: TM-T3986
1mg37,00€5mg79,00€10mg119,00€25mg274,00€50mg432,00€100mg638,00€500mg1.359,00€1mL*10mM (DMSO)87,00€LY-294002 hydrochloride
CAS:LY-294002 HCl (NSC 697286) is a stable PI3K inhibitor (IC50: 0.5-0.97 µM) and prevents autophagosome formation.Fórmula:C19H17NO3·HClPureza:99.95% - 99.98%Forma y color:SolidPeso molecular:343.81DS-7423
CAS:DS-7423: a dual PI3K/mTOR inhibitor; IC50s—PI3Kα: 15.6 nM, mTOR: 34.9 nM, PI3Kβ: 1,143 nM, PI3Kγ: 249 nM, PI3Kδ: 262 nM.
Fórmula:C22H27F3N10O2Pureza:99.98%Forma y color:SolidPeso molecular:520.51Gedatolisib
CAS:Gedatolisib (PF-05212384) is a highly effective dual inhibitor targeting the PI3Kα/γ (IC50: 0.4/5.4 nM)and mTOR (IC50: 1.6 nM) in the PI3K/mTOR signalingFórmula:C32H41N9O4Pureza:98% - 99.36%Forma y color:SolidPeso molecular:615.73KU-0060648
CAS:KU-0060648 is a dual inhibitor of DNA-PK and PI3Kα, PI3Kβ, PI3Kδ with IC50 of 8.6 nM and 4 nM, 0.5 nM, 0.1 nM respectively, less inhibition of PI3Kγ.Fórmula:C33H34N4O4SPureza:98.75%Forma y color:SolidPeso molecular:582.71Desmethyl-VS-5584
CAS:Desmethyl-VS-5584 is a dimethyl analog of VS-5584, which is a novel and highly selective PI3K/mTOR kinase inhibitor for the treatment of cancer.Fórmula:C16H20N8OPureza:>99.99%Forma y color:SolidPeso molecular:340.38Duvelisib
CAS:Duvelisib (INK1197, IPI-145) is a selective inhibitor of phosphatidylinositol 3-kinase (PI3K) and p100δ.Cost-effective and quality-assured.Fórmula:C22H17ClN6OPureza:98.87% - 99.74%Forma y color:SolidPeso molecular:416.86GNE-317
CAS:GNE-317, a PI3K/mTOR inhibitor, can pass through the blood-brain barrier (BBB).Fórmula:C19H22N6O3SPureza:98.42% - 99.54%Forma y color:SolidPeso molecular:414.48Ref: TM-T6845
2mg46,00€5mg66,00€10mg97,00€25mg202,00€50mg279,00€100mg358,00€200mg525,00€1mL*10mM (DMSO)73,00€CZC24832
CAS:CZC24832 is a selective inhibitor of PI 3-kinase γ.Fórmula:C15H17FN6O2SPureza:99.08% - 99.12%Forma y color:SolidPeso molecular:364.4Ref: TM-T1949
1mg50,00€2mg66,00€5mg97,00€10mg145,00€25mg240,00€50mg356,00€100mg525,00€1mL*10mM (DMSO)110,00€Deoxyelephantopin
CAS:Deoxyelephantopin: anti-inflammatory, hepatoprotective, wound healing, antitumor; blocks NF-κB, MAPK, PI3K/Akt, β-catenin pathways.Fórmula:C19H20O6Pureza:99.6% - 99.71%Forma y color:SolidPeso molecular:344.36Acalisib
CAS:Acalisib (CAL-120) (GS-9820) is a potent and selective inhibitor of PI3Kδ.Fórmula:C21H16FN7OPureza:98.99% - ≥95%Forma y color:SolidPeso molecular:401.4Parsaclisib hydrochloride
CAS:Parsaclisib hydrochloride (INCB050465 HCl) is a selectve PI3Kδ inhibitor with antitumor activity. Parsaclisib demonstrates potent activity.Fórmula:C20H23Cl2FN6O2Pureza:98%Forma y color:SolidPeso molecular:469.34GNE-477
CAS:GNE-477 is a potent and efficacious dual PI3K/mTOR inhibitor.Fórmula:C21H28N8O3S2Pureza:98.88% - 99.55%Forma y color:SolidPeso molecular:504.63Ref: TM-T3692
1mg44,00€2mg57,00€5mg93,00€10mg138,00€25mg286,00€50mg447,00€100mg677,00€1mL*10mM (DMSO)92,00€TG 100713
CAS:TG 100713 is a pan-PI3K inhibitor against PI3Kγ, PI3Kδ, PI3Kα and PI3Kβ with IC50 of 50 nM, 24 nM, 165 nM and 215 nM, respectively.
Fórmula:C12H10N6OPureza:98.17%Forma y color:SolidPeso molecular:254.25BEBT-908
CAS:BEBT-908 (PI3Kα inhibitor 1) is a selective PI3Kα inhibitor (IC50 <0.1 μM). BEBT-908 also inhibits HDAC (0.1 μM≤IC50≤1 μM).Fórmula:C23H25N9O3SPureza:99.67%Forma y color:SolidPeso molecular:507.57Ref: TM-T16529
1mg94,00€5mg222,00€10mg334,00€25mg562,00€50mg802,00€100mg1.063,00€200mg1.459,00€1mL*10mM (DMSO)249,00€PI3K-IN-1
CAS:PI3K-IN-1 (Voxtalisib Analogue) is a dual inhibitor of mTOR/PI3K, mostly for p110γ , also inhibits DNA-PK and mTOR.Fórmula:C31H29N5O6SPureza:97.03% - 98%Forma y color:SolidPeso molecular:599.661,3-Dicaffeoylquinic acid
CAS:1,3-Dicaffeoylquinic acid (CYNARIN) is a natural product. It shows antioxidant and choleretic properties and is a potential immunosuppressive agent.Fórmula:C25H24O12Pureza:98% - 98.81%Forma y color:SolidPeso molecular:516.45Ref: TM-T5736
1mg39,00€5mg74,00€10mg96,00€25mg156,00€50mg220,00€100mg325,00€200mg472,00€1mL*10mM (DMSO)108,00€Euscaphic acid
CAS:Euscaphic acid has anti-diabetic and anti-inflammatory effects, blocking IKK/MAPKs and NF-κB activation by disrupting TRAF6/IRAK1/TAK1 clustering.Fórmula:C30H48O5Pureza:98.93%Forma y color:SolidPeso molecular:488.7AS-605240
CAS:AS-605240 is an effective and specific inhibitor of PI3Kγ (IC50/Ki: 87.8 nM).Fórmula:C12H7N3O2SPureza:97% - 99.91%Forma y color:SolidPeso molecular:257.27HS-173
CAS:HS-173 is an effective PI3Kα inhibitor (IC50: 0.8 nM).
Fórmula:C21H18N4O4SPureza:99.33% - 99.64%Forma y color:SolidPeso molecular:422.46Serabelisib
CAS:Serabelisib (INK1117) is a p110α/β/γ/δ inhibitor (IC50: 15/4.5/1.9/13.39 μM).Fórmula:C19H17N5O3Pureza:98.41% - 99.5%Forma y color:SolidPeso molecular:363.37TG100-115
CAS:TG100-115 is a PI3Kγ/δ inhibitor (IC50: 83/235 nM), with fewer effects on PI3Kα/β.Fórmula:C18H14N6O2Pureza:99.22% - 99.26%Forma y color:SolidPeso molecular:346.34Ref: TM-T2672
1mg43,00€5mg85,00€10mg115,00€25mg210,00€50mg378,00€100mg588,00€500mg1.216,00€1mL*10mM (DMSO)92,00€Sophocarpine
CAS:Sophocarpine, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects.Fórmula:C15H22N2OPureza:99.89%Forma y color:SolidPeso molecular:246.35Quercetin Dihydrate
CAS:Quercetin Dihydrate (Sophoretin) is a flavonoid natural product that activates or inhibits the activity of many proteins. It activates SIRT1 and inhibits PI3K.Fórmula:C15H10O7·2H2OPureza:97.77% - 99.79%Forma y color:Yellow SolidPeso molecular:338.2725(R,S)-Ruscogenin
CAS:25(R,S)-Ruscogenin is able to regulate the PI3K/Akt/mTOR signalling pathway, and hinder the metastasis of hepatocellular carcinoma.Fórmula:C27H42O4Pureza:99.32% - 99.40%Forma y color:SolidPeso molecular:430.62Buparlisib
CAS:Buparlisib (BKM120) is an orally bioavailable specific oral inhibitor of the pan-class I PI3K (IC50s: 52/166/116/nM for p110α, p110β, and p110δ).Fórmula:C18H21F3N6O2Pureza:95.32% - 98.45%Forma y color:SolidPeso molecular:410.39Ref: TM-T1827
5mg59,00€10mg80,00€25mg88,00€50mg109,00€100mg137,00€200mg222,00€500mg403,00€1mL*10mM (DMSO)65,00€Quercetin
CAS:Quercetin (Sophoretin) is a natural flavonoid and is an agonist of SIRT1.Fórmula:C15H10O7Pureza:96.29% - 98.05%Forma y color:Sensitive To Exposure To Air And Light Insoluble In Water Alcoholic Solutions Taste Very Bitter (Ntp 1992)Peso molecular:302.24MOMIPP
CAS:MOMIPP: PIKfyve inhibitor, spurs macropinocytosis, crosses blood-brain barrier, curbs glioblastoma growth.Fórmula:C18H16N2O2Pureza:99.66%Forma y color:SolidPeso molecular:292.33Ref: TM-T33467
1mg114,00€5mg160,00€10mg250,00€25mg455,00€50mg628,00€100mg944,00€1mL*10mM (DMSO)245,00€(+)-Nortrachelogenin
CAS:(+)-Nortrachelogenin is a lignan isolated from Wikstroemia indica C.A. Meyer (Thymelaeaceae). (+)-Nortrachelogenin possesses antileukemic activity.Fórmula:C20H22O7Pureza:99.88%Forma y color:SolidPeso molecular:374.38Alpelisib hydrochloride
CAS:Alpelisib hydrochloride (BYL-719 HCl) is a potent PI3Kα inhibitor (IC₅₀ = 5 nM) with selectivity and oral bioavailability. Cancer research.Fórmula:C19H23ClF3N5O2SPureza:97.64%Forma y color:SolidPeso molecular:477.93Samotolisib
CAS:Samotolisib (LY3023414) inhibits PI3K, DNA-PK, mTOR; tested for solid tumors including breast and colon cancer.
Fórmula:C23H26N4O3Pureza:98.41% - 99.69%Forma y color:SolidPeso molecular:406.48RLY-2608
CAS:RLY-2608 is a variant PI3Kalpha inhibitor that inhibits tumor growth in a PIK3CA mutant xenograft model.Fórmula:C29H14ClF5N6O2Pureza:98.62% - 98.7%Forma y color:SolidPeso molecular:608.91740 Y-P
CAS:740 Y-P (740YPDGFR) is a PI3K activator with cell permeability,binds GST fusion proteins containing the N-and C-terminal SH2 domains of p85. Low-Cost!Fórmula:C141H222N43O39PS3Pureza:98.3% - 99.87%Forma y color:SolidPeso molecular:3270.7BGT226 maleate
CAS:BGT226 maleate (NVP-BGT226) is a class I PI3K/mTOR inhibitor for PI3Kα/β/γ (IC50: 4/63/38 nM) .
Fórmula:C28H25F3N6O2·C4H4O4Pureza:97.75% - 98.78%Forma y color:SolidPeso molecular:650.6GSK2292767
CAS:GSK2292767 is a potent and selective PI3Kδ inhibitor.Fórmula:C24H28N6O5SPureza:98%Forma y color:SolidPeso molecular:512.58CNX-1351
CAS:CNX-1351 is a potent and isoform-selective targeted covalent PI3Kα inhibitor.
Fórmula:C30H35N7O3SPureza:99.66% - 99.83%Forma y color:SolidPeso molecular:573.71PI3Kdelta inhibitor 1
CAS:PI3Kdelta inhibitor 1 is a potent, selective and orally available inhibitor of PI3Kδ with an IC50 of 1.3 nM.Fórmula:C27H38N6O5SPureza:98%Forma y color:SolidPeso molecular:558.69PI3Kγ inhibitor 1
CAS:PI3Kγ inhibitor 1 is a inhibitor of PI3Kδ and PI3Kγ.Fórmula:C32H26N8O2SPureza:98%Forma y color:SolidPeso molecular:586.67PI3Kγ inhibitor 7
CAS:PI3Kγ Inhibitor 7 (compound 2) is a potent, orally active agent that selectively inhibits PI3Kγ with an IC50 of 3.42 nM and demonstrates antitumor activity [1].Fórmula:C31H25N9O2Pureza:98%Forma y color:SolidPeso molecular:555.59FD2056
CAS:FD2056 is a potent, orally active PI3K inhibitor, with IC50 values of 0.30, 0.80, 1.10, and 0.42 nM against PI3Kα, PI3Kβ, PI3Kγ, and PI3Kδ, respectively.Fórmula:C23H17ClN6O2SPureza:98%Forma y color:SolidPeso molecular:476.94AZ2
CAS:AZ2 is a highly selective, active PI3Kγ inhibitor (pIC50=9.3) for use in inflammatory and immune disorders.Fórmula:C20H23N3O2SPureza:99.25%Forma y color:SolidPeso molecular:369.48Nemiralisib
CAS:Nemiralisib (GSK-2269557) is an oral PI3Kδ inhibitor (pKi 9.9) for treating respiratory diseases like COPD.Fórmula:C26H28N6OPureza:99.91%Forma y color:SolidPeso molecular:440.54PI3K/mTOR Inhibitor-2
CAS:Potent PI3K/mTOR Inhibitor-2 targets PI3Kα/β/δ/γ & mTOR (IC50: 3.4, 34, 16,1, 4.7 nM); exhibits antitumor effects.Fórmula:C20H13ClF2N4O4SPureza:96.16%Forma y color:SolidPeso molecular:478.86Ref: TM-T12459
1mg55,00€5mg138,00€10mg215,00€25mg358,00€50mg512,00€100mg692,00€200mg888,00€1mL*10mM (DMSO)144,00€Vps34-IN-2
CAS:Vps34-IN-2 is a potent and selective Vps34 inhibitor (IC50s: 2 and 82 nM on the Vps34 enzymatic assay and the GFP-FYVE cellular assay, respectively).Fórmula:C18H25F3N4O3Pureza:98%Forma y color:SolidPeso molecular:402.41PI3Kδ-IN-3
CAS:PI3Kδ-IN-3 (TC KHNS 11) is a PI3Kδ inhibitor with an IC50 value of 9 nM.PI3Kδ-IN-3 has a favorable pharmacokinetic profile and inhibits B cell function.Fórmula:C28H24N6O3Pureza:99.8%Forma y color:SolidPeso molecular:492.53PI3K-IN-6
CAS:PI3K-IN-6 is an oral active and highly selective inhibitor of phosphoinositide 3-kinase (PI3K) β/δ(IC50 values of 7.8 nM/5.3 nM , respectively).Fórmula:C17H14Cl2FN9OPureza:98%Forma y color:SolidPeso molecular:450.26PI3Kα-IN-13
CAS:PI3Kα-IN-13 (Compound 18a), a PI3Kα inhibitor with an IC50 of 2.5 nM, effectively induces apoptosis and hampers the proliferation of various cancer cell lines,Fórmula:C21H19N5O3Pureza:98%Forma y color:SolidPeso molecular:389.41PI4KIII β inhibitor 3
CAS:PI4KIII beta inhibitor 3 is a novel and high effective inhibitor of PI4KIIIβ (IC50 of 5.7 nM).Fórmula:C22H22N8OSPureza:98%Forma y color:SolidPeso molecular:446.53CAL-130 Hydrochloride
CAS:CAL-130 Hydrochloride is a PI3Kδ and PI3Kγ inhibitor (IC50s: 1.3 and 6.1 nM).Fórmula:C23H23ClN8OForma y color:SolidPeso molecular:462.94AZD3458
CAS:AZD3458 is a potent and remarkably selective inhibitor of PI3Kγ (PI3Kγ, PI3Kα, PI3Kβ, and PI3Kδ with pIC50s of 9.1, 5.1, <4.5, and 6.5 , respectively).Fórmula:C20H23N3O4S2Forma y color:SolidPeso molecular:433.54PI3K-IN-10
CAS:PI3K-IN-10 is a potent inhibitor of pan-PI3K .Fórmula:C23H19ClN6OPureza:98%Forma y color:SolidPeso molecular:430.89CHMFL-PI3KD-317
CAS:CHMFL-PI3KD-317: potent PI3Kδ inhibitor, IC50=6 nM, orally active, >10x selective vs. PI3K isoforms, anti-cancer.Fórmula:C21H24ClN5O3S2Pureza:99.16%Forma y color:SolidPeso molecular:494.03Ref: TM-T10804
1mg92,00€5mg216,00€10mg329,00€25mg593,00€50mg893,00€100mg1.216,00€1mL*10mM (DMSO)235,00€
