PI3K
Los inhibidores de PI3K son compuestos que bloquean la actividad de las fosfoinosítido 3-quinasas (PI3Ks), una familia de enzimas involucradas en una amplia gama de procesos celulares, incluidos el crecimiento, la proliferación, la supervivencia y el metabolismo. La vía PI3K/Akt/mTOR a menudo está desregulada en el cáncer, lo que convierte a PI3K en un objetivo clave para la terapia contra el cáncer. Los inhibidores de PI3K son herramientas fundamentales para estudiar la transducción de señales, la biología del cáncer y el desarrollo de terapias dirigidas. En CymitQuimica, ofrecemos una variedad de inhibidores de PI3K para apoyar su investigación en señalización celular, oncología y desarrollo terapéutico.
Se han encontrado 231 productos de "PI3K"
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CAL-130
CAS:CAL-130 is a PI3Kδ and PI3Kγ inhibitor (IC50s: 1.3 and 6.1 nM).Fórmula:C23H22N8OPureza:98%Forma y color:SolidPeso molecular:426.47PI3K-IN-38
CAS:PI3K-IN-38: oral PI3K inhibitor, IC50 of 0.541 µM, anticancer, anti-inflammatory, halts tumors in vivo.Fórmula:C20H24N6O2Pureza:99.89%Forma y color:SolidPeso molecular:380.44PI3K-IN-9
CAS:PI3K-IN-9 is a potent and selective inhibitor of PI3Kδ(IC50 of 8.9 nM).Fórmula:C19H23N7OPureza:98%Forma y color:SolidPeso molecular:365.43PQR514
CAS:PQR514: more potent pan-PI3K inhibitor than predecessor PQR309, exhibits strong anticancer activity in vitro and in OVCAR-3 model.
Fórmula:C16H20F2N8O2Pureza:98.77% - 99.19%Forma y color:SolidPeso molecular:394.38TGX-115
CAS:TGX-115 inhibits PI 3-K p110β (IC50=0.13μM) & p110δ (IC50=0.63μM), treats various cardiovascular diseases.Fórmula:C20H20N2O3Pureza:99.48%Forma y color:SolidPeso molecular:336.38Ref: TM-T24873
1mg190,00€5mg447,00€10mg610,00€25mg858,00€50mg1.063,00€100mg1.350,00€200mg1.765,00€1mL*10mM (DMSO)369,00€NVP-BAG956
CAS:NVP-BAG956 is an ATP-competitive PI3K inhibitor (IC50s: 34/56/112/444 nM for PI3Kδ/PI3Kα/PI3Kγ/PI3Kβ).Fórmula:C28H21N5Pureza:99.25% - 99.80%Forma y color:SolidPeso molecular:427.5Ref: TM-TQ0313
1mg57,00€5mg120,00€10mg210,00€25mg424,00€50mg707,00€100mg1.293,00€200mg1.738,00€1mL*10mM (DMSO)133,00€AZ044
CAS:AZ044 is a potent, selective inhibitor of type III phosphatidylinositol-4-kinase alpha-subtype (PI4KIIIalpha).Fórmula:C24H27N3O3SPureza:99.5%Forma y color:SolidPeso molecular:437.55Ref: TM-T26698
1mg54,00€5mg114,00€10mg178,00€25mg409,00€50mg708,00€100mg1.153,00€200mg1.558,00€1mL*10mM (DMSO)126,00€SRX3207
CAS:SRX3207 is an inhibitor of Syk and PI3K and relieves tumor immunosuppression.Fórmula:C29H29N7O3SPureza:99.85%Forma y color:SolidPeso molecular:555.65GS-9901
CAS:GS-9901 is a selective, orally active and potent PI3Kδ inhibitor (IC50: 1 nM) for the study of non-Hodgkin's lymphoma and chronic lymphocytic leukemia.Fórmula:C22H17ClFN9OPureza:98.60% - 99.92%Forma y color:SolidPeso molecular:477.88NVP-QAV-572
CAS:NVP-QAV-572 is a inhibitor of PI3K(IC50 of 10 nM).Fórmula:C17H19F2N7O3S2Pureza:98%Forma y color:SolidPeso molecular:471.5MSC2360844
CAS:MSC2360844 is a potent, orally active and selective inhibitor of PI3Kδ(IC50 of 145 nM).Fórmula:C26H27FN4O5SPureza:99.54% - 99.9%Forma y color:SolidPeso molecular:526.58Ref: TM-T12115
1mg52,00€5mg116,00€10mg182,00€25mg354,00€50mg568,00€100mg900,00€200mg1.206,00€1mL*10mM (DMSO)135,00€LAS191954
CAS:LAS191954 is a selective, potent and orally active PI3Kδ inhibitor for inflammatory diseases treatment(IC50 : 2.6 nM).Fórmula:C20H15N9OPureza:98%Forma y color:SolidPeso molecular:397.39CAL-130 Racemate
CAS:CAL-130 Racemate is the racemate of CAL-130. CAL-130 is a PI3Kδ and PI3Kγ inhibitor (IC50s: 1.3 and 6.1 nM).Fórmula:C23H22N8OPureza:98%Forma y color:SolidPeso molecular:426.47GNE-490
CAS:GNE-490 is an effective inhibitor of pan-PI3K with IC50s of 3.5 nM, 25 nM, 5.2 nM, 15 nM for PI3Kα, PI3Kβ, PI3Kδ and PI3Kγ, respectively.Fórmula:C18H22N6O2SPureza:99.77%Forma y color:SolidPeso molecular:386.47Ref: TM-T22339
1mg85,00€2mg115,00€5mg188,00€10mg321,00€25mg509,00€50mg702,00€100mg932,00€200mg1.283,00€1mL*10mM (DMSO)205,00€PI3Kδ-IN-17
CAS:PI3Kδ-IN-17 (Compound S5) is a potent PI3K δ inhibitor, exhibiting an IC50 value of 2.82 nM and demonstrates significant efficacy in suppressing theFórmula:C23H24F3N7O2Pureza:98%Forma y color:SolidPeso molecular:487.48Ginsenoside Rk1
CAS:Ginsenoside Rk1 is a component created by processing the ginseng plant at high temperatures.Fórmula:C42H70O12Pureza:98.46% - 99.13%Forma y color:SolidPeso molecular:767.00PIK-inhibitors
CAS:PIK-inhibitors (MDK34597) is a pan PI3K inhibitors, an analog of PI-103.Fórmula:C19H17N5O2Pureza:96.98%Forma y color:SolidPeso molecular:347.37SAR-260301
CAS:SAR-260301 is an orally available and selective inhibitor of PI3Kβ (IC50: 23 nM).Fórmula:C19H22N4O3Pureza:99.74%Forma y color:SolidPeso molecular:354.4Ref: TM-T16841
2mg43,00€5mg65,00€10mg87,00€25mg173,00€50mg264,00€100mg371,00€200mg523,00€1mL*10mM (DMSO)71,00€Zandelisib
CAS:Zandelisib is an inhibitor of phosphatidylinositol 3-kinase (PI3K)(p110δ, IC50 of 3.5 nM), and with antineoplastic activity.Fórmula:C31H38F2N8OPureza:99.88%Forma y color:SolidPeso molecular:576.68Ref: TM-T13386
1mg85,00€5mg177,00€10mg279,00€25mg487,00€50mg655,00€100mg900,00€1mL*10mM (DMSO)225,00€PI3Kδ-IN-1
CAS:PI3Kδ-IN-1 is an efficacious PI3Kδ inhibitor (IC50 of 1.7 nM).Fórmula:C22H20F3N7O2Pureza:99.85%Forma y color:SolidPeso molecular:471.44
