mTOR
Los inhibidores de mTOR son compuestos que inhiben la actividad de la Proteína diana de la rapamicina en mamíferos (mTOR), un regulador central del crecimiento celular, la proliferación, el metabolismo y la supervivencia. La vía de mTOR se altera con frecuencia en el cáncer y otras enfermedades, lo que convierte a mTOR en un objetivo crítico para la intervención terapéutica. Los inhibidores de mTOR se utilizan ampliamente en la investigación relacionada con el cáncer, el envejecimiento y los trastornos metabólicos. En CymitQuimica, ofrecemos una variedad de inhibidores de mTOR para apoyar su investigación en transducción de señales, oncología y desarrollo terapéutico.
Se han encontrado 163 productos de "mTOR"
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PI3K-AKT-mTOR Compound Library
A unique collection of 420 compounds targeting PI3K/Akt/mTOR signaling for research in PI3K/Akt/mTOR signaling, and drug discovery in diseases involved withForma y color:Odour SolidRef: TM-L1300
1mgA consultar30μL*10mM (DMSO)A consultar50μL*10mM (DMSO)A consultar100μL*10mM (DMSO)A consultar250μL*10mM (DMSO)A consultarDEPTOR-IN-1
CAS:DEPTOR-IN-1 is an inhibitor of DEPTOR with a Kd of 9.3 μM.Fórmula:C24H16Cl2FNO4Pureza:97.84%Forma y color:SolidPeso molecular:472.29FD274
CAS:FD274 is a potent dual PI3K/mTOR inhibitor with inhibitory effects on PI3Kα/β/γ/δ and mTOR, with IC50s of 0.65 nM, 1.57 nM, 0.65 nM, 0.42 nM, and 2.03 nM,Fórmula:C22H14ClFN6O2SPureza:98%Forma y color:SoildPeso molecular:480.9Thioether-cyclized helix B peptide, CHBP TFA
Thioether-cyclized helix B peptide, CHBP (TFA), is the trifluoroacetic (TFA) salt of CHBP.Fórmula:C56H93N19O22S·xC2HF3O2Pureza:98%Forma y color:SolidPeso molecular:1416.52 (free base)WYE-687
CAS:WYE-687 is a selective mTOR inhibitor (IC50: 7 nM), over 100x more selective for mTOR than PI3Kα/γ, affecting mTORC1/pS6K and mTORC2/P-AKT(S473).Fórmula:C28H32N8O3Pureza:99.93%Forma y color:SolidPeso molecular:528.61mTOR inhibitor-14
mTOR Inhibitor-14 (compound 14c) is a potent inhibitor of mTOR with minimal inhibition of CYP2C8 and has demonstrated the capability to inhibit tumor growth [1Pureza:98%Forma y color:Odour Solid(32-Carbonyl)-RMC-5552
CAS:(32-Carbonyl)-RMC-5552, a potent mTOR inhibitor, blocks mTORC1/C2, with pIC50 values >9 for p-P70S6K and p-4E-BP1, and 8~9 for p-AKT1/2/3.Fórmula:C93H134N10O24Forma y color:SolidPeso molecular:1776.141PF-06465603
CAS:PF-06465603 is a metabolite of PF-04691502, a highly potent and selective ATP competitive kinase inhibitor of class 1 PI3Ks and mTOR.Fórmula:C22H25N5O5Forma y color:SolidPeso molecular:439.46RMC-6272
CAS:RMC-6272 (RM-006) is a bi-steric mTORC1 inhibitor with selective potency over mTORC2 and shows greater effects than Rapamycin on TSC2-deficient tumors.Fórmula:C95H141FN6O27SForma y color:SolidPeso molecular:1850.25RMC-4627
CAS:RMC-4627 is a selective mTORC1 inhibitor that activates 4EBP1 and inhibits tumor growth.Fórmula:C93H141N11O23Forma y color:SolidPeso molecular:1781.17mTOR inhibitor 9f
CAS:mTOR inhibitor 9f is a selective mTOR inhibitor with IC50 of 1.25nM and 82nM for mTOR and PI3Kα, respectively.Fórmula:C25H23N5O2SPureza:99.18%Forma y color:SoildPeso molecular:457.55QL-IX-55
CAS:QL-IX-55 has a wide range of applications in life science related research.Fórmula:C24H14F4N4OForma y color:SolidPeso molecular:450.39Aschantin
CAS:Aschantin is a useful organic compound for research related to life sciences. The catalog number is T126072 and the CAS number is 13060-15-6.Fórmula:C22H24O7Forma y color:SolidPeso molecular:400.427MCX 28
CAS:MCX 28, a triple PI3K/mTOR/PIM inhibitor, displays low nanomolar activity.Fórmula:C25H19N5O4S3Forma y color:SolidPeso molecular:549.64AJ2-30
CAS:AJ2-30: Inhibits SLCl5A4, TLR9-B cell activation, MDP transport, NOD signaling; for inflammation study.Fórmula:C23H22N4Pureza:>99.99%Forma y color:SoildPeso molecular:354.45Ref: TM-T77644
1mg48,00€5mg101,00€1mL*10mM (DMSO)114,00€10mg167,00€25mg334,00€50mg537,00€100mg762,00€200mg1.018,00€RMC-5552
CAS:RMC-5552 selectively inhibits mTORC1 with ~40-fold selectivity over mTORC2, demonstrating anticancer activity and research utility.Fórmula:C93H136N10O24Forma y color:SolidPeso molecular:1778.16Anti-Phospho-MTOR (Ser2448) Antibody (2K503)
Anti-Phospho-MTOR (Ser2448) Antibody (2K503) is an antibody targeting Phospho-MTOR (Ser2448). Anti-Phospho-MTOR (Ser2448) Antibody (2K503) can be used in ELISA, WB, IHC, IF.Forma y color:Odour LiquidAnti-Phospho-mTOR (Ser2481) Antibody (4R8)
Anti-Phospho-MTOR (Ser2481) Antibody (4R8) is an antibody targeting Phospho-MTOR (Ser2481). Anti-Phospho-MTOR (Ser2481) Antibody (4R8) can be used in ELISA, WB, IF.Forma y color:Odour LiquidS6K1-IN-DG2
CAS:S6K1-IN-DG2(S6K1InhibitorDG2) is a potent p70S6K inhibitor with an IC50 value of less than 100 nM.Fórmula:C16H17BrN6OPureza:99.99%Forma y color:SolidPeso molecular:389.25
