mTOR
Los inhibidores de mTOR son compuestos que inhiben la actividad de la Proteína diana de la rapamicina en mamíferos (mTOR), un regulador central del crecimiento celular, la proliferación, el metabolismo y la supervivencia. La vía de mTOR se altera con frecuencia en el cáncer y otras enfermedades, lo que convierte a mTOR en un objetivo crítico para la intervención terapéutica. Los inhibidores de mTOR se utilizan ampliamente en la investigación relacionada con el cáncer, el envejecimiento y los trastornos metabólicos. En CymitQuimica, ofrecemos una variedad de inhibidores de mTOR para apoyar su investigación en transducción de señales, oncología y desarrollo terapéutico.
Se han encontrado 163 productos de "mTOR"
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S6K1-IN-DG2
CAS:S6K1-IN-DG2(S6K1InhibitorDG2) is a potent p70S6K inhibitor with an IC50 value of less than 100 nM.Fórmula:C16H17BrN6OPureza:99.99%Forma y color:SolidPeso molecular:389.25Omipalisib
CAS:Omipalisib (GSK2126458) is a small-molecule pyridylsulfonamide inhibitor of phosphatidylinositol 3-kinase (PI3K) with potential antineoplastic activity.Fórmula:C25H17F2N5O3SPureza:98% - 99.8%Forma y color:SolidPeso molecular:505.5Apitolisib
CAS:Apitolisib (RG 7422) is a PI3K inhibitor, used in cancer trials, targeting PI3Kα, β, δ, γ (IC50= 5, 27, 7, 14 nM).Fórmula:C23H30N8O3SPureza:98.28% - 99.64%Forma y color:SolidPeso molecular:498.6Torin 1
CAS:Torin 1 is an effective inhibitor of mTORC1/2 with (IC50: 2 nM/10 nM); has 1000-fold selectivity for mTOR than PI3K.Fórmula:C35H28F3N5O2Pureza:98.3% - 99.33%Forma y color:SolidPeso molecular:607.62NV-5138 hydrochloride
NV-5138 hydrochloride: a leucine analog, oral brain mTORC1 activator via Sestrin2, for antidepressant research.Fórmula:C7H14ClF2NO2Forma y color:SolidPeso molecular:217.64mTOR inhibitor-1
CAS:C-4 is a potential ATP-competitive inhibitor of mTOR. C-4 could inhibit cell growth and proliferation.Fórmula:C16H15BrN2O3Pureza:99.43%Forma y color:SolidPeso molecular:363.21G5-7
CAS:G5-7 is an oral JAK2 inhibitor targeting EGFR/STAT3 phosphorylation with potential for glioma research.Fórmula:C22H19F2NO3Pureza:97.3%Forma y color:SolidPeso molecular:383.39Ref: TM-T8742
1mg35,00€5mg71,00€1mL*10mM (DMSO)78,00€10mg96,00€25mg172,00€50mg248,00€100mg348,00€200mg470,00€PF-04691502
CAS:PF-04691502 is a potent and selective inhibitor of PI3K and mTOR kinases with antitumor activity.Fórmula:C22H27N5O4Pureza:96.27% - ≥95%Forma y color:SolidPeso molecular:425.48Ref: TM-T6251
1mg34,00€2mg43,00€5mg63,00€1mL*10mM (DMSO)65,00€10mg88,00€25mg117,00€50mg187,00€100mg333,00€AZD-8055
CAS:AZD8055 is an ATP-competitive mTOR inhibitor (IC50: 0.8 nM in MDA-MB-468 cells). It is ~1,000-fold selective for mTOR over all PI3K isoforms.Fórmula:C25H31N5O4Pureza:98% - 99.69%Forma y color:SolidPeso molecular:465.54Mito-LND
CAS:Mito-LND (Mito-Loidamine) is an orally active and mitochondria-targeted inhibitor of oxidative phosphorylation.Fórmula:C43H45BrCl2N3OPPureza:97.25% - 98.34%Forma y color:SolidPeso molecular:801.62Bimiralisib
CAS:Bimiralisib (PI3K-IN-2) is an orally bioavailable pan inhibitor of PI3K and inhibitor of the mTOR, with potential antineoplastic activity.Fórmula:C17H20F3N7O2Pureza:97.58% - 98.92%Forma y color:SolidPeso molecular:411.38Corynoxine
CAS:Corynoxine is a tetracyclic oxindole alkaloid isolated from Uncaria macrophylla.Fórmula:C22H28N2O4Pureza:96.83% - 99.93%Forma y color:SolidPeso molecular:384.47Salidroside
CAS:Salidroside is a bioactive phenolic glycoside compound isolated from Rhodiola rosea and is a prolyl endopeptidase inhibitor.Cost-effective and quality-assured.Fórmula:C14H20O7Pureza:97.81%Forma y color:Red-Brown Fine PowderPeso molecular:300.30Ref: TM-T2717
2mg34,00€5mg50,00€1mL*10mM (DMSO)55,00€10mg81,00€25mg130,00€50mg178,00€100mg268,00€200mg408,00€OSI-027
CAS:OSI-027 (ASP4786) is a selective and potent dual inhibitor of mTORC1 and mTORC2 with IC50 of 22 nM and 65 nM.Fórmula:C21H22N6O3Pureza:97.42%Forma y color:SolidPeso molecular:406.44Ref: TM-T6319
1mg39,00€2mg50,00€5mg81,00€1mL*10mM (DMSO)84,00€10mg131,00€25mg235,00€50mg369,00€100mg537,00€Polyphyllin I
CAS:Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax,Fórmula:C44H70O16Pureza:98% - 99.5%Forma y color:SolidPeso molecular:855.02Samotolisib
CAS:Samotolisib (LY3023414) inhibits PI3K, DNA-PK, mTOR; tested for solid tumors including breast and colon cancer.Fórmula:C23H26N4O3Pureza:98.41% - 99.69%Forma y color:SolidPeso molecular:406.48Lupiwighteone
CAS:Lupiwighteone has anti-angiogenesis potential, it also has anticancer and cancer preventive effects on SH-SY5Y cells.Fórmula:C20H18O5Pureza:98.92%Forma y color:SolidPeso molecular:338.35L-Leucine
CAS:L-Leucine is an essential amino acid vital for protein synthesis, metabolism, muscle and bone repair, blood sugar control, and wound healing.Fórmula:C6H13NO2Pureza:99.83%Forma y color:White Solid CrystallinePeso molecular:131.17Palomid 529
CAS:Palomid 529 (SG 00529) has been used in trials studying the treatment of Age-Related Macular Degeneration.Fórmula:C24H22O6Pureza:98.40% - 98.59%Forma y color:SolidPeso molecular:406.43GNE-477
CAS:GNE-477 is a potent and efficacious dual PI3K/mTOR inhibitor.Fórmula:C21H28N8O3S2Pureza:98.88% - 99.55%Forma y color:SolidPeso molecular:504.63Ref: TM-T3692
1mg44,00€2mg57,00€1mL*10mM (DMSO)92,00€5mg93,00€10mg138,00€25mg286,00€50mg447,00€100mg677,00€
