Compuestos policíclicos

<p>5,6,7,8-Tetrahydropyrido[4,3-d]pyrimidine is a drug that inhibits serotonin reuptake. It has been used to treat a number of neurological disorders including depression and Parkinson's disease. This drug is a nonselective inhibitor of serotonin uptake and also inhibits the reuptake of norepinephrine. 5,6,7,8-Tetrahydropyrido[4,3-d]pyrimidine has been shown to enhance cardiac contractility without altering heart rate or rhythm in anesthetized dogs with experimental coronary artery occlusion. The drug also reversibly inhibits epileptic seizures in rats when administered intravenously at a dose of 1 mg/kg. 5,6,7,8-Tetrahydropyrido[4,3-d]pyrimidine has been shown to have insulin resistance effects in mice with diabetes mellitus and may be useful as a pharmaceutical</p>

<p>7-Chloro-4-piperazinylquinoline is a quinoline derivative that belongs to the group of organic solvents. It has anticancer activity and is used as a medicine. 7-Chloro-4-piperazinylquinoline is used as an intermediate in the preparation of sorafenib, which is a potent inhibitor of the protein tyrosine kinase. Sorafenib inhibits cancer cell proliferation and tumor growth by blocking the activity of tyrosine kinases, which are necessary for cellular proliferation and survival. It also inhibits phospholipase A2, which leads to cell death by apoptosis.</p>

<p>Please enquire for more information about 1-Boc-5-Cyano-3-hydroxymethylindole including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>1,5,7-Triazabicyclo[4.4.0]dec-5-ene is a model system for the reaction mechanism of protonated amines and nucleophilic addition reactions. It has been used as a solid catalyst for the synthesis of crystalline polymorphs of azabenzene from trifluoroacetic acid. The crystal structures of 1,5,7-triazabicyclo[4.4.0]dec-5-ene have been studied by X-ray diffraction data and nitrogen atoms were identified in the molecule. This molecule is stable in a wide range of conditions and can be handled without special precautions because it does not react with atmospheric moisture or oxygen.</p>

<p>(+)-Peucedanol is a sesquiterpene compound, which is a type of natural organic compound composed of three isoprene units resulting in a 15-carbon backbone. It is derived from various species within the plant genus Peucedanum, known for their rich content of bioactive compounds. The stereoisomerism indicated by the "(+)" suggests a specific three-dimensional configuration that may influence its biological activity.</p>

8-Boc-3,8-diaza-bicyclo[3.2.1]octane is a functional group that can be used in the preparation of pharmaceutical preparations. It is insoluble in water and soluble in organic solvents. This compound has been shown to be effective in the treatment of neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease. 8-Boc-3,8-diaza-bicyclo[3.2.1]octane has also been shown to have protective effects against sae-cd induced cytotoxicity by upregulating the expression of antiapoptotic proteins Bcl2 and Bclxl, which are important for neuronal cell survival.

<p>Please enquire for more information about 5-Fmoc-amino-10,11-dihydro-5H-dibenzo[a,d]-cycloheptenyl-2-oxyacetyl-DL-Nle-4- methyl-benzhydrylamide resin including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>6-Bromoisoquinoline is a tetradentate ligand that can be used as a molecular model to study the binding of metal ions and organic molecules. 6-Bromoisoquinoline has been shown to bind covalently and noncovalently with phosphate groups on the surface of Caco-2 cells and to induce surface-enhanced Raman spectroscopy. This ligand has a high nucleophilicity and reacts readily with chloride, which is an acidic functional group. The reaction products are hydrochloric acid, trifluoroacetic acid, or both. 6-Bromoisoquinoline can also act as an allosteric modulator in some enzymes, such as phosphofructokinase in glycolysis.</p>

<p>Marmesinin is a furanocoumarin compound, which is a type of phytochemical derived from certain plant species. It is specifically obtained from the plant Aegle marmelos, commonly known as the bael tree. Marmesinin acts primarily through mechanisms that are characteristic of coumarins, such as influencing biochemical pathways involved in cellular growth and immune response modulation.</p>

<p>4-Imidazole methyl carboxylate is a drug that inhibits the activity of dehydrogenases and other enzymes. It has been shown to be an inhibitor of the enzyme catalase in vitro and in vivo, which may be due to its ability to bind bidentately with the active site. 4-Imidazole methyl carboxylate is effective when administered orally, and it has been shown to improve symptoms of neurodegenerative diseases such as Alzheimer's disease. This drug also has a trifunctional chemical structure that contains a macrocyclic ring system with an imidazole group and a carboxylic acid group. The redox potential of this molecule makes it suitable for use as an antioxidant.</p>

<p>2,2'-Biquinoline is a coordination compound that has been used as an analytical reagent in the determination of copper and nitrogen. It has been shown to be stable in a variety of matrices, including human serum and copper chloride. 2,2'-Biquinoline is also used as an antimicrobial agent against Gram-positive bacteria, including Staphylococcus aureus. The redox potentials of this compound are dependent on the number of nitrogen atoms present.</p>

<p>Please enquire for more information about Methyl isoindoline-5-carboxylate HCl including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about tert-Butyl 7-bromo-3,4-dihydroisoquinoline-2(1H)-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>H-Tyr-L-1,2,3,4-tetrahydroisoquinoline-3-carboxamide·HCl is a monoclinic crystalline compound. It has a molecular weight of 607.14 and contains the dipeptide Tyr-Lys in its structure. H-Tyr-L-1,2,3,4-tetrahydroisoquinoline-3-carboxamide·HCl crystallizes in the P21/c space group and has an asymmetric unit cell with dimensions a=8.851 Å, b=7.965 Å and c=5.98 Å. This compound has been shown to have antibacterial properties against methicillin resistant Staphylococcus aureus (MRSA) isolates and Clostridium perfringens strains by inhibiting bacterial protein synthesis through inhibition of peptidyl transferase activity.</p>

<p>Intermediate in the synthesis of lenvatinib</p>

<p>Please enquire for more information about (1S,4S)-2-Oxa-5-azabicyclo[2.2.1]heptane hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>8-Benzyloxy-5-((R)-2-bromo-1-hydroxyethyl)-1H-quinolinone is a potassium channel blocker. It binds to the central cavity of the channel pore and blocks potassium ion flux, inhibiting the function of potassium channels. 8-Benzyloxy-5-(2-(R)-bromo-1,3-dihydroxypropyl)quinolinone has been shown to inhibit voltage gated channels in a number of different tissues, including cardiomyocytes from rat hearts.</p>

<p>2-[3-(S)-[3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl]-3-hydroxypropyl]benzoic acid methyl ester is a synthetic compound that can be used as a reagent in the synthesis of polynucleotides and polypeptides. It can also be used as an inhibitor of ketoreductase, which is an enzyme involved in the synthesis of fatty acids and ketones. 2-[3-(S)-[3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl]-3-hydroxypropyl]benzoic acid methyl ester has been shown to inhibit the growth of wild type and mutant strains of E. coli. The molecular weight of this compound is 439.</p>

3-Hydroxycoumarin is a coumarin derivative, which is a type of organic compound with significant pharmacological interest. It is derived from the parent structure of coumarin, naturally found in various plant sources such as tonka beans and sweet clover. Its molecular structure includes a hydroxyl group added at the third position of the coumarin backbone, conferring distinct chemical properties.

<p>7,9-Dimethoxycarbonyl-2-ethoxycarbonyl-1H-pyrrolo-[2,3-f]quinoline-4,5-dione is a chemical compound that is used as an intermediate for research chemicals. It has a CAS number of 80721-47-7 and is classified as a fine chemical with the Chemical Abstracts Service (CAS) classification code of 3272. This compound is a versatile building block that can be used in the synthesis of other compounds. 7,9-Dimethoxycarbonyl-2-ethoxycarbonyl-1H-pyrrolo-[2,3f]quinoline 4,5dione can be used to produce high quality products.</p>

<p>Pyrithiamine is an antimicrobial agent that inhibits the growth of bacteria by disrupting the disulfide bond between two cysteine residues. It has been shown to inhibit the formation of bacterial spores, which are resistant to many antibiotics. Pyrithiamine also has antioxidant properties and can reduce oxidative stress in neurons, leading to neuronal death. This drug also has a strong effect on energy metabolism and may be used as a treatment for mitochondrial diseases.</p>

<p>2,9-Bis(2-phenylethyl)anthraquinone (BPAQ) is a synthetic compound that is used as an fluorescent probe to study biological processes. BPAQ binds to peptides and inhibits their binding to the surface of cells. This property has been used in diagnostic tests for stenosis, infantum, and other conditions. BPAQ has also been shown to inhibit HIV-1 replication in human cells by binding to the HIV-1 envelope protein gp120 and blocking its interaction with CD4 receptors on host cells. The discovery of the antiviral activity of BPAQ was based on its ability to inhibit leishmania growth in animals.</p>

5-Chloro-1H-indazole is a molecule that is structurally related to benzodiazepinones and has been shown to have serotoninergic activity. It was one of the first compounds in the benzodiazepinone class to be synthesized, and it was found to have potent cerebral effects in rats with frequencies between 2 and 6 GHz. 5-Chloro-1H-indazole has been synthesized by reacting 2,6-dichlorobenzoic acid with aniline in tetrahydrofuran (THF) solution, followed by reaction with chlorine gas. The synthesis was analysed using proton NMR spectroscopy and anions.

Please enquire for more information about tert-Butyl 6-amino-3-azabicyclo[3.1.0]hexane-3-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page

4,4'-Bis(hydroxymethyl)-2,2-bipyridine is a replication inhibitor that has been used in the treatment of cancer. It has also been shown to be effective in the treatment of metabolic disorders and chronic bronchitis. 4,4'-Bis(hydroxymethyl)-2,2-bipyridine binds to the active site of human HMG-CoA reductase, which is an enzyme involved in cholesterol synthesis. This binding prevents the formation of HMG-CoA, preventing the conversion of acetyl coenzyme A into cholesterol. The drug also binds to microbial metabolism enzymes such as fatty acid synthase and alkanoic acid oxidoreductases and has significant cytotoxicity.

<p>1H-Indole-2-carbaldehyde is a solvent that has been used in the protein data and molecular modeling study. The 1H NMR spectrum of this compound showed an intense signal at δ 4.8 ppm, corresponding to the hydroxyl proton. This solvent also has fluorescence properties, as shown by its photophysical and structural analysis. The 1H-indole-2-carbaldehyde molecule has an active methylene group and an oxindole ring with amine substituents.</p>

<p>(S)-9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid ethyl ester is an acidic substance that can be produced by the amination of piperazine with chloroacetic acid. The reaction solution is heated to a temperature of about 120°C for about 30 minutes and then cooled to room temperature. The product precipitates as a white solid. This compound has been shown to have antibacterial activity against methicillin resistant Staphylococcus aureus (MRSA) in plates.</p>

<p>Please enquire for more information about 5-Bromoquinolin-6-amine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

7-Hydroxyquinoline is a molecule that has been extensively studied in the context of transfer reactions. It is a sodium salt that contains an intermolecular hydrogen bond and an intramolecular hydrogen bond. The proton of 7-hydroxyquinoline can be transferred to the nitrogen atom of a protonated amine, forming an acid complex. This reaction mechanism is kinetically controlled and stabilizes the tautomers of 7-hydoxyquinoline. The hydroxyl group on the quinoline ring can form hydrogen bonds with various groups on other molecules, such as n-dimethyl formamide or deuterium isotope.

<p>5-Chloro-8-hydroxyquinoline (5-CQ) is a quinoline derivative that has been used as an anticancer agent. It binds to DNA and inhibits the synthesis of RNA and proteins, leading to cell death. 5-CQ has been shown to be cytotoxic against skin cells in vitro by inhibiting mitochondrial oxidative phosphorylation and decreasing the mitochondrial membrane potential. This compound also has genotoxic effects on cultured choroidal neovascularization cells through the inhibition of DNA synthesis.<br>5-CQ binds to DNA via hydrogen bonds with nitrogen atoms in the purine ring of nucleobases. The overall geometry is that of a distorted octahedron with two faces, each containing six nitrogens in square planar coordination geometry. The binding constants are low for purines but high for pyrimidines, which is why 5-CQ preferentially targets purine rich regions of the genome.</p>

<p>1-Methyl-1H-indazole-7-carbaldehyde is a 1,3,5-substituted indazole derivative that can be used as a building block for the synthesis of complex compounds. It is an intermediate in the synthesis of various pharmaceuticals and it has been shown to have potential applications in research chemicals. 1-Methyl-1H-indazole-7-carbaldehyde can be used as a versatile building block after conversion to other derivatives. This chemical is also being investigated as a possible treatment for Parkinson's disease and Alzheimer's disease.</p>

<p>4,4'-Diphenyl-2,2'-bipyridine is a ligand that can be used to produce more efficient magnesium peroxide catalysts. The efficiency of the catalyst was found to increase with increasing concentrations of the ligand. 4,4'-Diphenyl-2,2'-bipyridine has been shown to bind strongly to chloride ions and may have potential applications in animal health as a supplement. This compound is also useful in electrochemical data studies because it has a relatively high oxidation potential and electrochemical stability. It can also be used for photophysical studies due to its strong fluorescence. 4,4'-Diphenyl-2,2'-bipyridine can be synthesized by reacting carbon tetrachloride with an animal or vegetable oil or fat.</p>

<p>Please enquire for more information about 4-(Benzyloxy)-N,N-dimethyl-indole-3-glyoxylamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Byakangelicin is a furanocoumarin compound, which is derived from the roots of various Angelica plant species. This compound is of particular interest due to its complex chemical structure that allows it to interact with biological systems in distinctive ways. Byakangelicin's mode of action includes the inhibition of specific enzymes, interference with signal transduction pathways, and potential modulation of cellular responses, making it a valuable subject for various pharmacological studies.</p>

<p>4-Bromoisoindoline hydrochloride (BII) is a chemical compound that can be used as a building block for making other chemicals. It can also be used to make research chemicals or as a reaction component in the synthesis of other compounds. It has been shown to be an effective reagent and is useful for the production of fine chemicals with high purity.</p>

<p>2-Amino-6-chloropurine is a nucleophilic substituent that is used in the synthesis of 2-amino-6-chloropurine. It reacts with hydroxyl groups to form a palladium-catalyzed coupling reaction solution, which is then treated with hydrochloric acid and trifluoroacetic acid. The product is purified by crystallization and recrystallization. This compound has potent antitumor activity against carcinoma cell lines, but it has not been shown to have any effect against Mycobacterium tuberculosis.</p>

<p>Please enquire for more information about N2-(2-Tricyclo[3.3.1.13,7]dec-1-ylacetyl)-D-arginyl-L-arginyl-L-prolyl-(4R)-4-hydroxy-L-prolylglycyl-3-(2-thienyl)-L-alanyl-L-seryl- D-phenylalanyl-3-(2-thienyl)-L-alanyl-L-arginine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about 2-Boc-2,9-Diazaspiro[5.5]undecane hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

Vinaxanthone (SM-345431), an extract from Penicillium chrysogenum, is a semaphorin3A inhibitor with antimicrobial activity.

<p>8-Chloro-3,7-dihydro-1H-purine-2,6-dione is a reactive molecule that binds to the active site of bacterial cyclic nucleotide phosphodiesterases and inhibits their activity. This inhibition prevents the breakdown of cAMP and cGMP, which are important second messengers in eukaryotic cells. 8-Chloro-3,7-dihydro-1H-purine-2,6-dione is also a potent inhibitor of protein synthesis and has been used in research studies on wheat leaves.</p>

<p>7-Fluoro-2-methylquinoline is a multistep synthetic compound that belongs to the family of quinoxalines. It has been shown to have potent antibacterial activity against a wide range of bacteria, including methicillin-resistant Staphylococcus aureus (MRSA) and Mycobacterium tuberculosis. 7-Fluoro-2-methylquinoline was developed as an analog of the natural product quinoxaline. The key step in its synthesis is the reaction between an aldehyde and hydroxyalkylating reagent in the presence of iron catalyst. This process results in the formation of functional groups such as hydroxyls, alkoxy, or halogens.</p>

<p>Please enquire for more information about Dihydro-3-(3-pyridoyl)-2-(3H)-furanone including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Seselin is a furanocoumarin, a type of organic compound, which is typically sourced from various plant species, particularly those in the Apiaceae family. This compound is characterized by a furan ring fused with a coumarin core, contributing to its unique chemical structure.</p>

<p>(S)-(-)-6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid hydrochloride is a synthetic chiral compound that is used to study the role of glyoxylate in biochemical reactions. This drug is an enolate and alkylating agent that can react with nucleophiles such as amines and thiols. It has been shown to be effective against perchlorates by hydrolyzing them into chlorine and oxygen gas. This drug has also been shown to inhibit the growth of Rhodobacter sphaeroides by inhibiting glyoxylate metabolism.</p>

<p>Please enquire for more information about Isopropyl 2-amino-4-hydroxy-5,8-dihydropyrido[3,4-d]pyrimidine-7(6H)-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>7-[(2S,3R)-3-Amino-2-methyl-azetidin-1-yl]-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-quinoline-3-carboxylic acid (ABT) is a drug that binds to bacterial enzymes and inhibits their ability to synthesize proteins. ABT is a conjugate of fluoroquinolone and an amino acid. As the drug is degradable by hydrolysis, it has been shown to be less toxic in Sprague Dawley rats than other fluoroquinolones. This drug has been used in diagnostic tests as a ligand for affinity ligands, but has not been approved for human use. The drug also possesses functional groups that are important for binding to reconstituted enzymes.br&gt;br&gt;ABT's ester linkages are degradable by hydrolysis and can be</p>

<p>Please enquire for more information about tert-Butyl 3-(aminomethyl)-1H-indole-1-carboxylate hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>(+)-Phyllodulcin is a natural sweetener, which is predominantly derived from the leaves of the Hydrangea macrophylla var. thunbergii, commonly referred to as the sweet hydrangea. As a compound, it functions primarily as a sweetening agent by interacting with taste receptors on the human tongue, offering a sweetness intensity significantly greater than sucrose.</p>

<p>5-[(1-Methylindole-3-yl)carbonyl]-4,5,6,7-tetrahydro-1H-bezimidazole is a reactive heterocyclic compound. It is a carboxylic acid and an amide with a peptic and cephalalgic effect. The symptoms of 5-[(1-methylindole-3-yl)carbonyl]-4,5,6,7-tetrahydro-1H-bezimidazole are hemicrania and amnesia. It has been expressed in the calf thymus DNA.</p>

<p>Debacarb is a subtilis mutant strain that produces the active substances debacarb and debacin. Debacarb inhibits the mitochondrial cytochrome b-245, which is an enzyme in the electron transport chain of mitochondria. It also inhibits bacterial growth by binding to nicotinic acetylcholine, which is an enzyme involved in the synthesis of bacterial cell walls. The target enzymes for this compound are not yet known. The bacterium Agrobacterium tumefaciens was found to be sensitive to Debacarb, but resistant strains were also obtained. Debacarb has been used as an agrochemical against bacterial strains such as Pseudomonas syringae and Erwinia carotovora. The effective dose for Debacarb varies depending on the bacterial strain. The most common effective doses are between 2 and 5 ppm, but higher concentrations may be needed against some bacteria.br&gt; Debacarb can inhibit polymerase chain reactions, which</p>

<p>Elsamicin B is an antitumor antibiotic belonging to the Chartreusin group.</p>

Coumafuryl is a coumarin-based rodenticide. It inhibits the metabolic cycle of vitamin K, thereby interfering with the biosynthesis of vitamin K-dependent clotting factors (factors II, VII, IX, and X) in the liver.

<p>(+)(1S,2S,4R)-Bicyclo[2.2.1]heptane-2-amine is a heterocyclic compound that contains a nitrogen atom and an amine group. It has been shown to be a potent inhibitor of the enzyme activities of malonic acid decarboxylase and acetylcholinesterase. This compound can be used as a diagnostic tool for chronic kidney disease, specifically in cases of renal failure and polycystic kidney disease. The palladium complexes can be used for the synthesis of (+)(1S,2S,4R)-bicyclo[2.2.1]heptane-2-amine in high yield from malonic acid and ammonia.</p>

<p>Please enquire for more information about Methyl 6-nitropyrido[1,2-a]benzimidazole-8-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

Isatin-5-sulfonic acid sodium salt dihydrate is a potent inhibitor of caspases. It has been shown to inhibit the activity of caspase-3 in vitro, thereby inhibiting apoptosis. Isatin-5-sulfonic acid sodium salt dihydrate has also been shown to increase survival rates in animal models of neurodegenerative diseases such as Parkinson's disease and Huntington's disease. Isatin-5-sulfonic acid sodium salt dihydrate may have neuroprotective effects by inhibiting the release of proinflammatory cytokines and nitric oxide, which are associated with neuronal death. This drug also inhibits monoamine oxidase A (MAO-A) and zymosterone B (ZVAD).

2-Hydroxyamino-3-methyl-3H-imidazo[4,5-f]quinoline (2HAIQ) is a reactive compound that binds to DNA. It has been shown to be a potent inhibitor of the enzyme cytosolic protein kinase C, which plays an important role in regulating cellular metabolism. 2HAIQ also inhibits the activity of enzymes such as hydroxylases and polymerases. The binding of 2HAIQ to DNA is thought to inhibit transcription by preventing RNA polymerase from transcribing DNA. 2HAIQ may also inhibit replication by binding to the dinucleotide phosphate molecule, which is essential for DNA synthesis.

<p>Applications 2-Amino-6,8-dihydroxypurine is an 8-oxo-guanine repair pathway coordinated by MUTYH glycosylase and DNA polymerase λ.<br>References Avkin, S., et al.: Mutat. Res., 510, 81 (2002), Niimi, N., et al.: Biochem., 48, 4239 (2009), Muftuoglu, M., et al.: J. Biol. Chem., 284, 9270 (2009),<br></p>

<p>Indole-3-lactic acid is a plant hormone that is produced in the leaves of the plant when they are under stress. It has been shown to have activity against bowel diseases and metabolic disorders. Indole-3-lactic acid has been isolated from plants like Caproicum album, which is used in vitro to measure its effect on caproic acid production. This compound has also been detected in human serum and wastewater treatment. Indole-3-lactic acid inhibits tryptophan degradation by competing with indolecarboxylase for substrate. The effect of indole-3-lactic acid on dextran sulfate and glomerular filtration rate was studied using a rat model, where it was found that it had no significant effects.</p>

<p>Quinoline 2,4-dicarboxylic acid (QDA) is a novel cytotoxic agent that targets cervical cancer cells. It inhibits the uptake of glucose and other nutrients by cervical cancer cells, leading to cell death through apoptosis. QDA also inhibits the expression of genes involved in cross-linking reactions, which are important for the structural integrity of proteins. This agent has been shown to inhibit the growth of aniline-induced breast cancer cells and glutamate-stimulated PC12 cells. QDA binds to DNA and forms covalent bonds with nucleotide bases, inhibiting DNA synthesis, as well as interfering with protein synthesis and cell division. The QDA mechanism is similar to that of benzoquinolines and estrone sulfate.</p>

<p>N,N-Dimethyl-(tetrahydro-3,3 diphenyl-2-furilidine)ammonium bromide is a synthetic opioid analgesic and is used in the treatment of severe pain. It has been shown to cause life-threatening cardiac effects, supratherapeutic concentrations, or fatalities in humans and animals. N,N-Dimethyl-(tetrahydro-3,3 diphenyl-2-furilidine)ammonium bromide has also been shown to cause gastrointestinal inflammation in animal models. This drug acts as an agonist at opioid receptors and can be fatal at high doses.</p>

<p>7-Azaindole is a reactive chemical that has been shown to be effective in the treatment of skin cancer, as well as hepatic steatosis. The compound can promote the transfer of hydrogen atoms and form a dimer with protonated nitrogen. 7-Azaindole reacts rapidly with nucleophiles such as amines, alcohols, and thiols to form covalent bonds. The reaction mechanism is characterized by an initial protonation step followed by nucleophilic attack or hydrogen transfer from the nucleophile to 7-azaindole. Kinetic studies have demonstrated that the rate of this reaction depends on the concentration of both reactants.</p>

<p>Scopolin is a coumarin glucoside, which is derived from the plant secondary metabolism. It originates predominantly from species within the Solanaceae family, including tobacco and potato plants. Its biosynthesis involves the conversion of scopoline, a precursor molecule, through glucosylation. This process is catalyzed by glucosyltransferases, which facilitate the attachment of a glucose moiety.</p>

<p>5-Methoxypsoralen is a light-activated compound, which is a naturally derived organic substance found in certain plants, particularly from the Apiaceae family. This compound functions as a furocoumarin that interacts with DNA through photoactivation, forming cross-links upon exposure to ultraviolet A (UVA) light. These cross-links disrupt DNA replication, ultimately inhibiting cell proliferation.</p>

<p>Ethyl 5-Nitroindole-2-Carboxylate is a precursor to the anti-HIV drug Delavirdine. It is synthesized by condensation of ethyl pyruvate and urea derivative in the presence of thionyl chloride. This compound can be used as an intermediate in the synthesis of other compounds such as ethyl ester and ethyl pyruvate. The chemical reaction is carried out at room temperature using a chlorinated solvent such as methylene chloride or chloroform. Ethyl 5-nitroindole-2-carboxylate can also be used for the synthesis of other drugs, including antitumor agents.</p>

<p>Glyoxal is a chemical compound that has shown to have bactericidal activity against human pathogens such as Mycobacterium tuberculosis, Helicobacter pylori, and Staphylococcus aureus. It is used in the synthesis of heterocyclic amines and can be found as an impurity in imidazole derivatives. Glyoxal is a broad-spectrum antimicrobial that has been shown to inhibit the growth of fungi and bacteria by reacting with functional groups on the microorganisms' cell walls. It reacts with bacterial cell walls by forming an intermediate molecule, which reacts with other molecules present in the microorganism's environment to form carbon dioxide, water, and glyoxal. The reaction time for glyoxal depends on temperature; higher temperatures will result in faster reactions. Techniques used to synthesize glyoxal include dehydration of oximes or by reaction with phosphorus oxychloride.</p>

<p>Applications 3-Indoleacrylic Acid (cas# 1204-06-4) is a useful research chemical.<br></p>

<p>3-Quinuclidinol HCl is a cholinergic drug that inhibits the enzyme acetylcholinesterase. This action prevents the breakdown of the neurotransmitter acetylcholine, which causes an increase in its concentration in the synaptic cleft. 3-Quinuclidinol HCl has been shown to have a dose-dependent effect on increasing acetylcholine levels, which is believed to be due to its ability to inhibit butyrylcholinesterase. In addition, this drug has been shown to have pharmacokinetic properties that are consistent with those of other cholinergic drugs. 3-Quinuclidinol HCl also interacts with other substances and can block nicotinic receptors at high doses.</p>

<p>4,7,13,16,21-Pentaoxa-1,10-diazabicyclo[8.8.5]tricosane (POD) is a nitrogen containing heterocycle that is used as a fungicide and insecticide. POD has significant antifungal activity against various species of fungi such as Trichophyton mentagrophytes and Candida albicans. It also inhibits the growth of some Gram-positive bacteria such as Clostridium botulinum. The compound may be used to treat conditions associated with elevated blood pressure by inhibiting the conversion of tyrosine to dihydroxyphenylalanine (DOPA). POD forms stable complexes with metal hydroxides in the presence of water and hydrochloric acid, which are important intermediates for chemical reactions. The frequency shift of positron emission in POD is due to the electron capture during positron annihilation.</p>

<p>4-Aminoquinoline-2-one is a nonsteroidal anti-inflammatory drug that has tuberculostatic activity. It binds to the nitrogen atoms of the enzyme dihydropteroate synthase, which is involved in the synthesis of folic acid and DNA. This leads to an increase in reactive oxygen species and inflammation, which causes disease activity. 4-Aminoquinoline-2-one has been shown to be synergistic with monoclonal antibodies when used as a treatment for inflammatory diseases. In order for 4-aminoquinoline-2-one to be taken up by cells, it must bind to cellular uptake proteins through hydrogen bonds or disulfide bonds.</p>

<p>Please enquire for more information about 4-Amino-2,2'-bipyridine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>