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<p>7-Methylindole-3-acetic acid is a metabolite of indomethacin. It is excreted in the urine and has been found to be present in the tissues of monkeys. 7-Methylindole-3-acetic acid is excreted by the kidneys and it is not known how much of this compound is reabsorbed into the body. 7-Methylindole-3-acetic acid can be metabolized to form other metabolites, including 2,4,5,6 tetrahydropyridine (2,4,5,6 THP), which has been shown to produce DNA damage in rats. The metabolites are then excreted from the body through urination and feces.</p>

<p>Isosibiricin is a naturally occurring lignan, which is extracted from certain plant sources. This compound is derived from the genus Daphne, traditionally known for its diverse range of biologically active constituents. Its mode of action is primarily through the modulation of key signaling pathways involved in cell proliferation and apoptosis. Isosibiricin exhibits notable inhibitory effects on specific enzymes and receptors implicated in oncogenic processes, making it a subject of interest for cancer research.</p>

<p>Indole-3-glyoxylamide is a synthetic compound that was originally developed as a potential anti-cancer drug. It has been shown to inhibit glycogen synthase kinase 3 (GSK-3) and thereby reduce the production of proinflammatory cytokines in bowel disease. Indole-3-glyoxylamide also inhibits inflammatory bowel disease by inhibiting secretory phospholipase A2, which prevents the release of arachidonic acid from phospholipids. This synthesis is required for the production of prostaglandins and leukotrienes, which are involved in the inflammatory process. The compound has been shown to have immunomodulatory effects in chronic bronchitis, with an inhibitory effect on neutrophil chemotaxis, macrophage activity, and cytokine production. Indole-3-glyoxylamide has also been shown to be effective against cancer cells in vitro and in vivo animal models. It is metabolized through</p>

<p>4-Iodoisatin is a heterocyclic compound that can be synthesized by cross-coupling reactions. It has been shown to inhibit the production of prostaglandin E2, COX-2 protein, and tumor necrosis factor in mouse macrophages. 4-Iodoisatin also inhibits the production of protein kinase C (PKC) in these cells. 4-Iodoisatin can be modified into a dimer form with many different substitutions on the ring structure and this modification increases its potency as an inhibitor of PKC. Irradiation can decompose the compound into a single isomer that is more potent than either of the two isomers. This drug may have therapeutic potential for treatment of cancer, arthritis, and other inflammatory disorders.</p>

<p>7-Cyanoindole is a synthetic compound that can be synthesized from amino-acids. The synthesis of 7-cyanoindole starts with the hydration of cyanamide, which yields cyanogen chloride. This reaction is followed by the dehydration of this molecule to produce 7-cyanoindole. The fluorescence properties and lifetimes are dependent on the hydration and dehydrations states. Synthetically, 7-cyanoindole is used as a fluorescent probe for amino acids in solution. This probe has been shown to bind to amino acids at acidic pHs and fluoresce brightly at wavelengths around 400 nm. Industrialized methods for synthesis include reacting cyanoacetylene with ammonia or methylamine in the presence of silicane or silicon dioxide as a catalyst. Reaction yield is dependent on the method used and ranges from 10% to 100%.</p>

<p>7-Hydroxyindole is a biochemical that is produced by wild-type strains of Escherichia coli. It has been shown to inhibit the action of an efflux pump, which is a protein that pumps drugs and other foreign substances out of the cell. The alkoxy radical reacts with 7-hydroxyindole to form a hydroperoxide intermediate. This intermediate then reacts with molecular oxygen to form hydrogen peroxide, which may be responsible for the antimicrobial activity of 7-hydoxyindole. Studies have shown that this compound can also inhibit multidrug efflux pumps in Pseudomonas aeruginosa cells, which may lead to an increase in antibiotic uptake.</p>

<p>5,7-Dihydroxy-4-methylcoumarin monohydrate is an organic chemical compound, specifically a type of coumarin derivative. Coumarins are a class of naturally occurring aromatic compounds that are found in various plant sources, such as tonka beans, sweet clover, and other botanicals. This particular compound, with its distinct hydroxyl and methyl groups, falls under the broader category of hydroxycoumarins, which are of significant interest in biochemical research due to their various functional properties.</p>

<p>L(+)-Amethopterin hydrate is an immunosuppressant that suppresses the immune system by inhibiting RNA synthesis. It is a structural analogue of folic acid and has been shown to be effective in treating autoimmune diseases, such as rheumatoid arthritis. L(+)-Amethopterin hydrate is a neutral compound that is soluble in water and microsomal membranes, making it more easily absorbed through the gut than other compounds of this class. It also has been shown to have no toxic effects on cardiac cells at therapeutic concentrations. These properties make L(+)-Amethopterin hydrate an attractive candidate for treating autoimmune diseases when other treatments have failed.</p>

<p>Epoxybergamottin is a furanocoumarin derivative, which is a natural bioactive compound. It is primarily sourced from citrus fruits, particularly grapefruit. The primary mode of action of epoxybergamottin is the inhibition of cytochrome P450 enzymes, specifically CYP3A4. This enzyme is a major player in the metabolism of many pharmaceuticals, and its inhibition can lead to increased bioavailability and prolonged effects of drugs metabolized by this pathway.</p>

<p>Osthenol is a natural product compound, known for its osteogenic-promoting properties. It is derived from plant sources, specifically from the fruits of Cudrania tricuspidata, a member of the Moraceae family. This compound functions by modulating cellular activities associated with bone formation. Osthenol has been reported to promote the differentiation and maturation of osteoblasts, the bone-forming cells, through the activation of specific signaling pathways such as the BMP-2 and Wnt/β-catenin pathways. These pathways are crucial for enhancing the deposition of extracellular matrix and increasing the expression of osteogenic markers.</p>

<p>Please enquire for more information about 4,5-Dicyanoimidazole including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Ethyl 6-Bromoindole-2-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>5,5'-Diamino-2,2'-bipyridine is an acidic metalloporphyrin that has been shown to react with epoxides to form nucleophilic adducts. This compound can be used as a ligand for lanthanide ions and reacts with aminopyridine to form bromoethane. 5,5'-Diamino-2,2'-bipyridine has been shown to have carcinogenic properties and may induce bromoethane mutagenicity in the liver. This compound is also mutagenic when added to propylene carbonate. 5,5'-Diamino-2,2'-bipyridine is luminescent in air or water when exposed to UV light.</p>

<p>8-Methyl-3,8-diazabicyclo[3.2.1]octane dihydrochloride is a high quality reagent that is used as an intermediate in the synthesis of complex compounds. This compound has been shown to be useful as a scaffold for the synthesis of new compounds and is also a versatile building block for reactions in organic chemistry. 8-Methyl-3,8-diazabicyclo[3.2.1]octane dihydrochloride is also used as a speciality chemical and research chemical in various fields such as pharmaceuticals, agrochemicals, and other industries.</p>

<p>6-Methylpurine is a product of the nucleotide metabolism in E. coli, which is a model organism for protein synthesis. 6-Methylpurine inhibits protein synthesis and exerts significant cytotoxicity. It has been shown to inhibit the enzyme activities of DNA polymerase alpha, DNA ligase, and RNA polymerase, as well as other enzymes involved in nitrogen metabolism. 6-Methylpurine has been shown to be an analog of adenine and has a similar reaction mechanism. The uptake of 6-methyl purine by cells is mediated by hydrogen bonds with amino acid residues on the cell membrane surface. This molecule also forms glycosidic bonds with ribose sugar groups on cellular surfaces. 6-Methylpurine plays an important role in energy metabolism through its incorporation into glucose and glycogen molecules.</p>

<p>Ticarcillin is a bactericidal antibiotic that is used to treat many types of infections caused by gram-positive bacteria, such as Streptococcus pneumoniae, Enterococcus faecalis and Enterococcus faecium. Ticarcillin has been shown to be effective against antibiotic-resistant strains of bacteria, including multidrug efflux pumps. This drug also has been shown to inhibit the growth of gram-negative bacteria such as Escherichia coli and Pseudomonas aeruginosa. Ticarcillin is used in combination with clavulanic acid for the treatment of infections caused by beta-lactamase producing organisms. It is also used in wastewater treatment to inhibit the growth of gram-negative bacteria that are resistant to other antibiotics. Ticarcillin can interfere with other medications by inhibiting their metabolism through cytochrome P450 enzymes or through competition for protein binding sites.</p>

<p>5-Fluoroindole-2-carboxylic acid is a new substance that has been found to be an inhibitor of the influenza virus. It prevents the virus from replicating by inhibiting the synthesis of viral proteins and nucleic acids. 5-Fluoroindole-2-carboxylic acid can be prepared by dispersive solid phase extraction of a mixture of fluoroindole, fumaric acid, and potassium hydroxide in water. The compound has also been shown to potentiate the effects of carbamazepine on caspases and enhance mass spectrometric analysis for gaseous hydrochloric acid. 5-Fluoroindole-2-carboxylic acid produces antinociceptive effects in animals.</p>

<p>8-Methylxanthine is a metabolite of caffeine and theophylline. It has been shown to be a pro-inflammatory cytokine that stimulates the production of other pro-inflammatory cytokines such as interleukin (IL)-1β, IL-6, and tumor necrosis factor alpha (TNFα). 8-Methylxanthine is also a substrate for cytochrome P450 enzyme activity, which is responsible for metabolizing many drugs and other chemicals in the body. This compound has been detected in human liver and urine samples. 8-Methylxanthine has cytotoxic properties and may serve as an antioxidant. Mass spectrometric detection methods are used to identify this compound in biological fluids.</p>

<p>Methyl indolyl-3-glyoxylate is an active analogue of hepg2, a protein involved in the synthesis of prenylated proteins. It inhibits the prenylation of proteins and halides by binding to ATP, preventing the formation of a covalent bond between ATP and the protein. Methyl indolyl-3-glyoxylate has been shown to induce apoptosis in HeLa cells by inhibiting cell proliferation and DNA synthesis. This compound also causes g1 phase arrest, which may be due to its ability to alkylate DNA. Methyl indolyl-3-glyoxylate has also been shown to be effective against cancer cells in vitro and in vivo, particularly those that are resistant to other chemotherapeutic drugs.</p>

<p>Indole-2-carboxylic acid ethyl ester is a synthetic compound that binds to cancer cells. It has been shown to inhibit the growth of leukemia cells and breast cancer cells in vitro. Indole-2-carboxylic acid ethyl ester inhibits the binding of collagen to cells, which may be due to its ability to bind to β-carboline alkaloids on collagen. The binding of indole-2-carboxylic acid ethyl ester with these alkaloids prevents them from binding to collagen, thereby preventing the formation of new collagen fibers. This drug also inhibits aldehyde production, which is important for DNA synthesis in cancer cells.</p>

<p>(9R,11S,14S,16R,17R)-6,6,9-Trifluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-8,11,12,14,15,16-hexahydro-7H-cyclopenta[a]phenanthrene 3-one is a congestive heart failure drug that belongs to the group of cardiotonic drugs. It has high resistance to elution and is used in the diagnosis of autoimmune diseases. (9R,11S) 6-(1′Hexahydrocyclohexa[b]pyrrolo[2′1′b]indolizinium bromide) is a nitrogenous compound that has been employed as a pharmaceutical preparation for the treatment of cardiac disorders. The biological properties of (9R) 11-(2′Hydroxyacetyl</p>

<p>7-[(Dimethylamino)methyl]-2,2,4-trimethyl-1,2-dihydroquinolin-6-ol is a chemical compound that belongs to the group of fine chemicals. It is a versatile building block and useful intermediate for research chemicals. 7-[(Dimethylamino)methyl]-2,2,4-trimethyl-1,2-dihydroquinolin-6-ol is also a speciality chemical with high purity and quality. CAS No. 300690-44-2</p>

<p>3-Cyclohexyl-1-[4-[2-(7-methoxy -4,4-dimethyl-1,3-dioxo-isoquinolin -2-yl)ethyl]phenyl]sulfonyl-urea is a drug that inhibits the enzyme DPPIV, which breaks down the incretin hormone glucagon-like peptide (GLP)-1. It may be used to treat diabetes by regulating blood glucose levels. This drug has been shown to reduce postprandial blood glucose levels in patients with type 2 diabetes. 3CYCSU is also capable of reducing body weight and food intake in mice. The mechanism of action of this drug is not fully understood, but it appears to have an effect on the cytosolic calcium ion concentration and may reduce inflammatory responses in cells. 3CYCSU is a promising potential treatment for infectious diseases such as Hepatitis C virus (HCV).</p>

<p>N-(1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-ylmethyloxycarbonyl-1,8-diamino-3,6-dioxaoctane is a polymerase that has been developed for use in vaccines and as an agrochemical for the control of plant diseases. This enzyme has been shown to have high activity against cancer cells, including lung cancer cells and breast cancer cells. It is also autofluorescent and can be used as a cell marker in flow cytometry experiments. N-(1R,8S,9s)-Bicyclo[6.1.0]non-4-yn-9-ylmethyloxycarbonyl-1,8-diamino-3,6-dioxaoctane also has antiinflammatory effects on macrophages by inhibiting the production of proinflammatory cytokines such as IL 12p</p>

<p>Hypoxanthine is a nucleoside that is found in human cells. It is synthesized from guanine by the enzyme, xanthine oxidoreductase. Hypoxanthine is also produced from xanthine by adenosine deaminase and converted back to xanthine, which can then be reused for DNA synthesis. Hypoxanthine has been shown to inhibit the growth of photosynthetic bacteria, such as Rhodopseudomonas viridis and Rhodobacter sphaeroides. This inhibition may be due to an equilibrative nucleotide effect on the folate receptor. The x-ray diffraction data collected from the chrysanthemum flower (a source of hypoxanthine) showed that hypoxanthine has a calcium salt structure.</p>

<p>5-Ethylindole-2-carboxylic acid is an organic compound that is a decarboxylation product of indole. It can be obtained by catalytic dehydrogenation of ethyl ester or 5-ethylindole-2-carboxylic acid. It has been shown to inhibit the growth of bacteria and fungi, as well as to have anti-inflammatory properties.</p>

<p>N-(4-Hydroxyphenyl)-5-methyl-2-1H-pyridone is a molecule that is found in plasma samples and has been shown to inhibit the growth of cells. It is a potent inhibitor of tubulointerstitial injury, which is the most common type of kidney disease. The mechanism of this drug has been shown to involve the inhibition of primary amino acid uptake. This compound also inhibits urea synthesis and decreases plasma concentrations by increasing the rate of elimination. In addition, it has been shown to have an inhibitory effect on growth factors such as EGF, bFGF, IGF-1, and PDGF. N-(4-Hydroxyphenyl)-5-methyl-2-1H-pyridone can be synthesized by heating at high temperatures (thermally activated).</p>

<p>Ferene is an iron chelate that has been shown to have a number of beneficial effects on iron homeostasis. Ferene has been used in the treatment of chronic viral hepatitis, and it has also been shown to be effective against galleria mellonella. Ferene is a metal chelate, which means that it is a type of molecule that contains two metal ions. The metal ions are usually connected by a central atom, such as oxygen or nitrogen. Ferene disodium salt can be synthesized in the lab using the chemiluminescence method and polymerase chain reaction (PCR). It is also possible to isolate ferene from human serum or from a model system.</p>

<p>6-(Dimethylamino)purine (6-DAP) is a purine nucleoside that acts as an inhibitor of the transcription factor leukemia inhibitory factor (LIF). 6-DAP binds to the response element in the promoter region of LIF and blocks the binding of LIF to this site. This prevents transcription of LIF, which leads to cell cycle arrest. 6-DAP also has inhibitory effects on skin cells and inhibits the formation of fetal bovine serum protein in a model system. 6-DAP binds to nuclear DNA and alters its structure, which may cause problems with DNA replication or transcription.</p>

<p>5-Chloro-1,10-phenanthroline (5CP) is a molecule that has been used in the study of DNA oxidation. 5CP has been shown to be an effective inhibitor of oxidative dna damage and can be used for the prevention of mutations caused by reactive oxygen species. This compound was also found to inhibit the growth of L1210 murine leukemia cells, which is due to its ability to bind to potassium ions. 5CP has been shown to have significant binding constants with DNA and protein molecules. It also has a very high level of ancillary activity and can be used as a catalyst in transfer reactions.</p>

<p>1,1'-Dimethyl-4,4'-bipyridinium diiodide (DMBI) is a hydrophobic compound that is soluble in organic solvents. It has been validated as a new optical probe for the detection of hydrogen peroxide by spectroscopic techniques. DMBI reacts with hydrogen peroxide to form an excited state molecule (a radical species) which produces a photocurrent when irradiated with light. The wavelength of the photogenerated current can be used to determine the concentration of hydrogen peroxide present. DMBI can also be used to detect hydrophilic compounds such as urea or creatinine. The reduction products formed by the reaction with these compounds are more hydrophilic and can be detected by this technique.</p>

<p>Alloisoimperatorin is a naturally occurring furanocoumarin compound, which is extracted from certain plant species, primarily those belonging to the Apiaceae family. As a type of coumarin derivative, it is synthesized through intricate plant metabolic pathways involving the precursors umbelliferone and isopentenyl pyrophosphate, among others.</p>

<p>Indole-7-carboxylic acid is a tetrahydropyridine that can be prepared by formylation of indole-7-carboxylic acid with formaldehyde and hydroxylamine. It is also the reaction product of dimethoxybenzene and cyanoindole in the presence of a base. Indole-7-carboxylic acid has been used in the synthesis of several drugs, including metronidazole and nitrofurantoin.</p>

<p>Byakangelicol is a naturally occurring furanocoumarin, which is a type of organic compound found predominantly in the roots of certain plants, such as Angelica dahurica. This compound is synthesized through the plant's secondary metabolic pathways, primarily as a defense mechanism against herbivores and pathogens. Byakangelicol exerts its biological effects primarily through the inhibition of various enzymatic pathways, such as cytochrome P450s and monoamine oxidase, which are key in processes like drug metabolism and neurotransmitter regulation.</p>

<p>Brequinar sodium is a drug that belongs to the class of quinoline carboxylic acid derivatives. It has been shown to be effective in the treatment of infectious diseases and bowel disease. Brequinar sodium inhibits bacterial growth by binding to DNA-dependent RNA polymerase, thereby preventing transcription and replication. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Brequinar also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.</p>

<p>7-Methylindole is a biochemical substance that is synthesized in the body. It is produced in the liver, and it can be found in the brain, heart, and kidney. 7-Methylindole has been shown to have cancer-fighting properties. 7-Methylindole binds to DNA by methylating nucleic acid bases, which causes a change in the genetic code. This leads to tumor cells being more sensitive to treatment with other substances that inhibit DNA synthesis or repair, such as anthranilate and 5-methoxyindole.</p>

<p>7-Fluoro-2-methyl-1H-indole is a chemical compound that can be used as a building block to synthesize other organic compounds. The compound is also useful as a reagent in reactions such as the conversion of nitrobenzene to aniline. 7-Fluoro-2-methyl-1H-indole is soluble in acetone, chloroform, and ether. It has CAS number 432025-24-6, which identifies it as a fine chemical with many uses.</p>

<p>6-Chloroisatin is a potent inhibitor of bacterial growth that binds to the 50S ribosomal subunit. It has been shown to have strong inhibitory activity against tuberculosis and sulphamethoxazole-resistant strains of Mycobacterium tuberculosis. 6-Chloroisatin inhibits bacterial growth by binding to the 50S ribosomal subunit, thereby preventing protein synthesis and cell division. The electron deficient form of 6-chloroisatin reacts with the electron rich sulphamethoxazole by displacement of chloride ion from the sulphonamide ring, forming a regiospecific product that inhibits bacterial respiration. This reaction system is inhibited by activated carbon, which may be a potential therapeutic strategy for patients with drug resistant tuberculosis.</p>

<p>The 6-methylcoumarin is a benzalkonium chloride that can be used as a stabilizer for biological samples. It has been shown to inhibit the activity of coumarin derivatives, which are receptors that are involved in the transmission of pain signals in the brain. The 6-methylcoumarin is also able to inhibit signal peptide, which is a protein that is secreted by cells and functions as a messenger between cells. This compound was found to have hypoglycemic effects due to its ability to stimulate glucose uptake in the body.</p>

<p>5-Benzyloxyindole-3-acetic acid is a synthetic chemical that is used as a plant growth regulator. It inhibits the uptake of other plant nutrients, such as nitrates and phosphate ions by roots, which leads to decreased plant growth. This compound also has an inhibitory effect on membranes and morphology. The inhibition of membrane transport can lead to cell death, which can be seen in the case of plants treated with this chemical. 5-Benzyloxyindole-3-acetic acid has been shown to affect the response pathway of plants at temperatures between c1-c3 degrees Celsius.</p>

<p>4,4'-Dibromo-2,2'-bipyridine is a nucleophilic compound that can react with a wide range of electrophiles. It has been used in medications as a thermally stable and non-toxic ligand for metal ions. 4,4'-Dibromo-2,2'-bipyridine is an efficient ligand for the coordination of many transition metals. This compound also has high values in light emission and is used in crystallography to study protein binding sites. The n-oxide form of 4,4'-dibromo-2,2'-bipyridine has biological properties that have not yet been studied.</p>

<p>N,N'-4,4'-Bis(benzyl-2-boronic acid)-bipyridinium dibromide is a high quality reagent that can be used as an intermediate for the synthesis of complex organic compounds. It is a complex compound that contains boronic acid and bipyridinium moieties. N,N'-4,4'-Bis(benzyl-2-boronic acid)-bipyridinium dibromide is useful in the synthesis of fine chemicals and speciality chemicals. It has versatile building block properties and can be used as a reaction component in many chemical reactions.</p>

<p>1,1'-Bicyclohexyl]-1-carboxylic acid (BCX) is a metal salt that is soluble in water. BCX has a quadratic structure and is a cyclohexanecarboxylic acid derivative. It can be made by the reaction between formic acid and chloride. BCX is used as an anti-diarrheal agent for the treatment of chronic diarrhea. It has been shown to have high entrapment efficiency and high efficiency when synthesized with dicyclomine. This technique uses formic acid as the solvent, which reacts with chloride to produce BCX.</p>

<p>1,3,9-Trimethylxanthine is a naturally occurring purine alkaloid that has been shown to have cytosolic calcium ion-antagonistic properties. It can also act as an antioxidant by donating electrons to free radicals and inhibiting lipid peroxidation. This compound is found in coffee beans and other sources of caffeine. It binds to the receptor for adenosine, which causes the antagonistic effects on intracellular calcium concentration. Trimethylxanthine can also be used to treat ventricular arrhythmias and increase locomotor activity in mammals. Trimethylxanthine has been shown to be effective in wastewater treatment as it removes organic pollutants from water by oxidizing them with hydrogen peroxide or chlorine gas.</p>

<p>3-Methyl-8-quinolinesulfonyl chloride (3MQSC) is a reaction product of 1,2,4-trioxane and thionyl chloride. 3MQSC is used as an intermediate in the production of l-citrulline from chloroacetic acid. It reacts with paraformaldehyde to form a solid phase synthesis catalyst. 3MQSC catalyzes the reaction between phosphorus pentachloride and chlorine to produce ethyl formate and hydrogen chloride gas. This process is industrialized for the production of ethyl formate, which is used for the manufacture of acetic acid, chlorinated solvents, polymers, and plastics. The high yield of this process makes it one of the most popular routes for producing ethyl formate. Catalysis by 3MQSC can be achieved at low temperature and pressure due to its resistance to heat and low boiling point.</p>

<p>Please enquire for more information about Ethyl 5-chloropyrazolo[1,5-a]pyrimidine-3-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>5-Bromo-4-chloroindolyl 1,3-diacetate (5BCDA) is a clinical response predictor of postoperative radiotherapy. It is an acr20 response predictor for the diagnosis of chronic hepatitis C and the disease activity index in women with genital herpes. 5BCDA has been found to be effective in reducing levels of IL-17a and IL-17f, which are cytokines that are important for immune responses. 5BCDA has also been shown to be effective in treating infectious diseases such as malaria and tuberculosis.</p>

<p>5,6-Dichloroindole is a chemical compound that contains a functional group with acidic properties. The compound has been shown to inhibit the activity of bafilomycin A1, which is an inhibitor of vacuolar ATPase. This inhibition leads to an increase in intracellular phosphate levels and an accumulation of lysosomal membrane proteins. 5,6-Dichloroindole has also been found to inhibit bone resorption in gramine-fed rats. It also has anti-inflammatory effects and inhibits the growth of zoobotryon pinnatum cells and algal cells. 5,6-Dichloroindole can be used as a molecular descriptor for predicting the presence or absence of bryozoan species in a sample.</p>

<p>5-Amino-1H-imidazole-4-carboxamide is a potent inhibitor of inosine monophosphate dehydrogenase (IMPDH). This enzyme converts inosine 5'-monophosphate (IMP) to xanthosine 5'-monophosphate (XMP) and is essential for the synthesis of purines. By inhibiting IMPDH, 5-amino-1H-imidazole-4-carboxamide prevents the formation of XMP, which leads to the depletion of purines, thereby inhibiting DNA synthesis. In addition to its role as an anti-inflammatory agent, this drug has been shown to reduce disease activity in bowel disease patients by reducing nitrate reductase activity. The molecule has also been shown to inhibit protein kinases such as PKC and MAPK/ERK kinases.</p>

<p>N,N'-Thiocarbonyldiimidazole is a potent inhibitor of the enzyme acetylcholinesterase. It is used in research as an inhibitor molecule for receptor activity and to study the mechanism of action of other drugs. N,N'-Thiocarbonyldiimidazole inhibits the production of ester hydrochloride by rat liver microsomes and muscle cell proliferation. In addition, this compound has been shown to be a protonophore that can transport protons across membranes without energy input. This can be done through Langmuir adsorption isotherm and electrochemical impedance spectroscopy.</p>

<p>Acetyl columbianetin is a natural compound, which is a type of secondary metabolite derived primarily from plant sources. This compound is part of a broader category of phytochemicals known for their diverse bioactive properties. Acetyl columbianetin is specifically sourced from certain species within the Apiaceae family, commonly found in traditional medicine.</p>

<p>3,3'-Diindolyl is a molecule that belongs to the class of oxindoles. Oxindoles are bioactive molecules that are formed by the reduction of 3,3'-dihydroxyindole (oxindole). The borohydride reduction of 3,3'-dihydroxyindole yields 3,3'-diindolyl. It has been shown to have anti-inflammatory properties and can be used for the treatment of inflammatory diseases such as congestive heart failure. 3,3'-Diindolyl is also an acidic compound and therefore can be used as an acidic buffer in pharmacopeia. It reacts with peroxide to form an aldehyde after oxidation. This reaction is catalyzed by sodium borohydride reduction or hydrogen peroxide. The borohydride reduction of 3,3'-diindolyl yields 2-hydroxy-1-(2-hydroxyethyl) indole (oxindole).</p>

<p>2-Azaspiro[3.3]heptane HCI is a fine chemical that has many uses in research, manufacturing, and other industries. It is a versatile building block that can be used as an intermediate or reaction component for the synthesis of organic compounds. 2-Azaspiro[3.3]heptane HCI is also a speciality chemical because it has many applications in the pharmaceutical and agrochemical industries. This compound can be used as a reagent for the determination of carboxylic acids, alcohols, and amines by paper chromatography and high performance liquid chromatography (HPLC). 2-Azaspiro[3.3]heptane HCI is also useful in the synthesis of peptides and other complex compounds, such as diazepam.</p>

<p>Indole-5-carboxylic acid is a chemical species that contains a heterocyclic ring with five atoms, one of which is a carboxyl group. It is an intermediate in the biosynthesis of tryptophan and histidine in the body. Indole-5-carboxylic acid has been used as a ligand to immobilize copper, nickel, palladium, and platinum on conductive supports. It has also been used for the structural analysis of dopamine by hybridization experiments and for the detection of mismatched hydrogen bonding interactions. This compound can be detected using FT-IR spectroscopy or electrochemical impedance spectroscopy.</p>

<p>1-Benzyl-1H-indole-2-carboxylic acid is a molecule that binds to chemokine receptors and has been used in screening assays as a chemical probe of chemokine receptor binding. It has been shown to be an antagonist of the CXCR3 receptor, with high affinity and selectivity. 1-Benzyl-1H-indole-2-carboxylic acid is also an antagonist of the CCR5 receptor, with low affinity. This compound was discovered by screening for novel antagonists of chemokines.</p>

<p>Imperatorin is a furanocoumarin compound, which is a natural product primarily isolated from plants in the Apiaceae family, such as Angelica dahurica and Citrus species. This compound is characterized by its unique chemical structure that includes a furan ring fused to a coumarin backbone. Imperatorin exerts its biological activities through multiple modes of action, including the modulation of enzymatic activity, interference with cellular signaling pathways, and binding to specific biological targets.</p>

<p>8-Hydroxyquinoline-2-carboxylic acid is a 3-hydroxyanthranilic acid derivative that is often used as a biomarker of urine. The 8OHQA can be synthesized from 3-hydroxyanthranilic acid by the action of xanthine oxidase and hydrogen peroxide, and it has been shown to be an inhibitor of protein synthesis. This inhibition may be due to its ability to form hydrogen bonds with the hydroxyl group on the ribose side chain and its ability to coordinate with metals. 8OHQA has been shown to have anti-inflammatory effects in bladder cancer cells, which may be due to its ability to inhibit prostaglandin synthesis.</p>

<p>6-Methylmercaptopurine is an important metabolite of 6-methylmercaptopurine, which is a vital component of the nucleotide synthesis pathway. It is used in analytical methods to determine levels of nucleotides, as well as in biological studies for its effect on autoimmune diseases. 6-Methylmercaptopurine can inhibit replication by inhibiting the methyltransferase enzyme.</p>

<p>7-Hydroxy-1,2,3,4-tetrahydroquinoline (7OH-THQ) is a fluorophore that can be used to detect the presence of cancer cells. It is a linker and labile and can be synthesized from the lactam 7-hydroxypyrazolo-[4,3-a]pyridin-5(6H)-one. The synthesis of 7OH-THQ is possible by reacting 4-(dimethylamino)benzenesulfonyl chloride with 2,2'-dithiolethane in the presence of sodium hydroxide. 7OH-THQ has been shown to be effective as an anticancer drug in vitro assays for colon and breast cancer cells. It also has fluorescence properties that are sensitive to acidic conditions and pH levels.</p>

<p>6-Trifluoromethylindole is a carbamic acid that can be synthesized with the help of a sulfoxides. Carbamic acid reacts with an aryl halide to form an unsymmetrical biaryl. 6-Trifluoromethylindole has been shown to act as a modulator in Friedel-Crafts reactions, which may be used for the synthesis of heterocycles. This chemical has also been shown to react with alkyl chlorides and sulfonium salts to form carbamic acids and sulfoxides, respectively.</p>

<p>1,10-Phenanthroline·HCl·H2O is a chemical compound that has been used for the preparation of samples for spectroscopic analysis. The compound is chemically stable and resistant to hydrolysis, making it suitable for long-term storage. 1,10-Phenanthroline·HCl·H2O has an inhibitory effect on bitter taste receptors in the mouth. It also has a hydroxyl group and a carbonyl group, which can react with acid molecules to form hydrogen ions and water. 1,10-Phenanthroline·HCl·H2O belongs to the class of metal ion sequestrants and can be used to remove aluminium from solutions. The molecular formula of this compound is C14H12N2O4Cl2. The structural formula is shown below:<br><br>[[image:1,10-phenanthroline-hcl-h2o.png]]</p>

<p>7-Benzyloxindole-3-carboxaldehyde (BXA) is an assembled molecule that can be synthesized in a scalable and catalytic manner. BXA is an unwanted product that arises from the reaction of 7-benzyloxyindole with adrenaline. The hydrogenolysis of BXA yields the enantiomeric 7-benzyloxyindole, which has been shown to possess anti-inflammatory properties. When debenzylated by hydrogenolysis, crystallization of the byproduct is observed.</p>

<p>2,3,3-Trimethylindolenine is a reactive aromatic hydrocarbon that has been synthesized by the coordination complex of nitric acid and sodium carbonate. It has a hydroxyl group in the 2 position and is used as an intermediate for the synthesis of hemicyanine. 2,3,3-Trimethylindolenine is soluble in nonpolar solvents such as benzene or hexane. Its light exposure can cause it to react with oxygen to form nitro groups. The structure of 2,3,3-Trimethylindolenine includes two nitrogen atoms in the alpha position.</p>

<p>4,4'-Bis(diethylmethylphosphonate)-2,2'-bipyridine is a molecule that is covalently tethered to the copper oxide surface. The coordination of the 4,4'-bis(diethylmethylphosphonate)-2,2'-bipyridine ligand with the copper oxide surface is catalytic and bifunctional. This molecule has been shown to be able to coordinate with two different metal ions as well as act as a ligand for other metal ions. It can also be functionalized in order to create new molecules with different properties.</p>

<p>2-Methylbenz[c,d]indole is an indole. It exhibits a number of spectroscopic properties including the presence of a strong absorption band at 290 nm and a weak one at 430 nm. 2-Methylbenz[c,d]indole is not active against bacteria.</p>

<p>Please enquire for more information about 1-Methylindole-3-acetamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>(1S,4S)-1,7,7-Trimethyl-3-(Trifluoroacetyl)Bicyclo[2.2.1]Heptan-2-One is a white solid with a melting point of -76.8°C and a boiling point of 265°C at 10 mm Hg. It has the following functional groups: particle, luminescent, lanthanide, stabilizer, ligand, voltammetry, thermally stable and has nmr spectra that show light emission and coordination chemistry. This compound is a sulfoxide but can also be considered to be a phosphine or an amine depending on its structural features. The compound's nature is dependent on the temperature and pressure as well as the solvent it is being dissolved in.&gt;&gt;END&gt;&gt;</p>

<p>6-Chloro-5-ethylisatin is a fine chemical that can be used as a building block for making other compounds, including pharmaceuticals and bioactive agents. It is also a versatile building block that can be used in the synthesis of many different types of compounds. 6-Chloro-5-ethylisatin is an intermediate, which means it is a substance that is used to make other substances. It can also act as a reagent in reactions and as a scaffold for complex molecules.</p>

<p>Reduces brain amyloid plaques; induces neprilysin expression</p>

<p>Daphnetin-8-glucoside is a natural phenolic glucoside compound derived from plants of the Thymelaeaceae family, specifically from the Daphne genus. This compound is produced by the glycosylation of daphnetin, a coumarin derivative found in various botanical sources. The glycoside linkage enhances its solubility and stability, facilitating its bioavailability. Daphnetin-8-glucoside exhibits potent antioxidant and anti-inflammatory activities, mediated through the scavenging of free radicals and inhibition of pro-inflammatory cytokine production. Additionally, it modulates signal transduction pathways involved in cellular oxidative stress responses.</p>

<p>1-Acetyl-5-bromoindole is a high quality reagent that is useful as an intermediate in the synthesis of a wide range of complex compounds. It can be used as a speciality chemical for research purposes or to make other chemicals. 1-Acetyl-5-bromoindole is also needed for the synthesis of indoles, which are useful scaffolds and building blocks in organic chemistry. This compound can be used to form reactions with other chemical compounds and can be used to create versatile building blocks.</p>

<p>(S)-(-)-3-Aminoquinuclidine 2HCl is a cholinergic agonist that has been shown to be effective in inducing the release of acetylcholine from brain synaptosomes. This drug binds to the nicotinic acetylcholine receptor (nAChR) and inhibits the action of the enzyme acetylcholinesterase, thereby increasing the concentration of acetylcholine in the synaptic cleft. The drug is also able to cross the blood-brain barrier and bind to receptors on neurons. It has been shown that this drug can be used as an imaging agent for molecular magnetic resonance tomography (MRT), with high sensitivity and specificity.</p>

<p>6-Mercaptopurine is a purine analog that suppresses the production of white blood cells by inhibiting the enzyme thiopurine methyltransferase. It has been used to treat bowel disease and also for long-term suppression of the immune system in patients with autoimmune diseases. 6-Mercaptopurine is metabolized to 6-mercaptopurine, which is then converted to dinucleotide phosphate (dNTP) by group P2 enzymes. This conversion allows 6-mercaptopurine to inhibit dNTP synthesis and cell division. The effects of 6-mercaptopurine are potentiated when given in conjunction with azathioprine, another drug that inhibits purine metabolism. 6-Mercaptopurine is not active against human serum albumin or erythrocytes because it cannot be cleaved into an active form by these proteins. However, it does inhibit enzyme activities such as DNA polymerase, RNA polymerase, and protein</p>

<p>Isoindoline is a compound that is used to treat bowel diseases. It is an inhibitor of jak1 and has been shown to be effective in the treatment of inflammatory bowel disease. The reaction mechanism of this drug is not fully understood, but it has been hypothesized that its activity may be due to inhibition of dpp-iv, which blocks the activation of T cells. Isoindoline was found to have low toxicity in h9c2 cells and redox potentials are expected to be low. This drug has also been shown to inhibit the synthesis of fatty acids by inhibiting the action of acyl-coenzyme A: diacylglycerol acyltransferase 2 (ACADS).</p>

<p>5-Methoxy-2,3-dihydroindoline is a methoxy compound that is substituted with a methyl group. It has been shown to be an effective hydrogen transfer agent in cyclopentenone reactions, and can also be used as a sensor for nitroaromatic compounds. 5-Methoxy-2,3-dihydroindoline can be synthesized by the reaction of methoxylated aniline with sodium ethoxide in acetonitrile. This reaction produces the desired product in high yield (70%), and it can also be used for the methylation of secondary amines in good yield (80%). 5-Methoxy-2,3-dihydroindoline is potently active when titrated against benzo[a]pyrene.</p>

<p>7H-imidazo[4,5-d]pyrimidine is a small molecule that exhibits receptor activity against toll-like receptors. It has been shown to inhibit the production of proinflammatory cytokines and chemokines in HL60 cells. 7H-imidazo[4,5-d]pyrimidine also inhibits the activities of enzymes involved in purine metabolism and cellular metabolic processes, as well as intracellular targets including protein kinases, phosphatases and transcription factors. 7H-imidazo[4,5-d]pyrimidine has been shown to be effective against solid tumours such as murine sarcoma virus and plant tumors. This drug also inhibits the enzymatic activity of p2y receptors that are involved in inflammation and platelet aggregation.</p>

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<p>6-Methoxyindoline-2,3-dione is an indole alkaloid that has been isolated from the leaves of plants in the genus Apiaceae. It is synthesized by a reaction system that involves the oxidation of 6-methoxyindole to the corresponding oxindole and subsequent reduction to the desired product. The cytotoxicity of 6-methoxyindoline-2,3-dione has been demonstrated using a fluorescent assay with cancer cells. The compound binds to and activates cb2 receptors, which are expressed on immune cells and have been shown to be involved in inflammatory processes.</p>

<p>4,6-Dimethoxyindole is a molecule that can be used as an amide or chloride. The molecular modeling study indicated that the 4,6-dimethoxyindole is hydrophobic and has a molecular weight of 164.4 g/mol. In the acetylation reaction, the 4,6-dimethoxyindole was synthesized with an acetyl group on one side of the molecule and an acetate group on the other side of the molecule. This molecule has shown to have anticholinesterase activity in vitro and can be used as an antibiotic. The synthesis of this molecule was confirmed by X-ray diffraction analysis, which showed that it had a crystal structure with two molecules in space group P2(1)2(1).</p>