Compuestos policíclicos

<p>Applications 3-Hydroxyindole is a mutation product of toluene-4-monooxygenase (T4MO), that gets spontaneously converted to indigo. Used in the preparation of indolyl-oxadiazoles with anticonvulsant activity.<br>References Rajak, H. et al.: Int. J. Pharm. Sci. Nanotech., 2, 661 (2009); McClay, K. et al.: Appl. Environ. Microbiol., 71, 5476 (2005); Berry, A. et al.: J. Ind. Microbiol. Biotech., 28, 127 (2002)<br></p>

<p>Applications Indazole-3-carboxylic Acid is an indole derivatives useful in treatment of pain and inflammation.<br>References Khanna P., et al.: Biochemistry, 40, 1441 (2001);<br></p>

<p>Applications 1-Ethyl-1,2-dihydro-2,2,4-trimethyl-7-quinolinol is a reagent used in the preparation of fluorescent dyes and can be applied toward labeling of biological macromolecules.<br>References Liu, W., et.al., Faming Zhuanli Shenqing, 21, (2020);<br></p>

<p>Applications 3-(Bromomethyl)-2-cyclopropyl-4-(4-fluorophenyl)quinoline is used to prepare artificial HMG-CoA reductase inhibitors. It is also used to synthesize pitavastatin calcium via stereoselective Wittig olefination reaction.<br>References Hiyama, T., et al.: Bull. Chem. Soc. Japan, 68, 364 (1995); Fabris, J., et al.: Synth., 44, 1700 (2012)<br></p>

<p>Applications Intermediate in the preparation of P2X7 antagonists<br>References Donnelly-Roberts, D., et al.: Neuropharmacol., 56, 223 (2009), Perez-Medrano, A., et al.: J. Med. Chem., 52, 3366 (2009),<br></p>

<p>Applications Isoquinoline is used in the synthesis of nitrated indenoisoquinolines as a potent topoisomerase I inhibitor.This compound is a contaminant of emerging concern (CECs).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Morrell, A., et. al.: J. Med. Chem., 49, 7740 (2006)<br></p>

<p>Applications 6-​Benzyloxy-​7-​methoxy-​3,​4-​dihydro-​isoquinoline is a reactant used in the synthesis of VMAT2 imaging agents.<br>References Liu, C. et al.: Chiral., 25, 215 (2013);<br></p>

<p>Applications 6-Chloroisatin (cas# 6341-92-0) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 3-Amino-4,5,6,7-tetrahydro-1H-indazole (cas# 55440-17-0) is a useful research chemical.<br></p>

<p>Applications 6-Benzylaminopurine can be used as reagent/reactant in pharmacological activity and synthesis preparation for modification of the length and structure of the linker of N6-benzyladenosine modulates its selective antiviral activity against enterovirus 71.<br>References Drenichev, M., S.: Eur. J. Med. Chem., 111, 84-94 (2016);<br></p>

<p>Applications A useful intermediate for drug discovery research.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Caldwell, J., et al.: Tet. Lett., 48, 1527 (2007)<br></p>

<p>Applications 3-BROMOPHENANTHRENE (cas# 715-50-4) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 5-Fluoroindole is a reactant used in various syntheses. It was used in the synthesis of Spirotetrahydro β-Carbolines (Spiroindolones), which is a new class of potent and orally efficacious compounds for the treatment of malaria. 5-Fluoroindole was also a reactant in direct indole and pyrrole couplings to carbonyl compound in total synthesis of Acremoauxin A and Oxazinin 3.<br>References Richter, J., et al.: J. Am. Chem. Soc., 129, 12857 (2007); Yeung, B., et al.: J. Med. Chem., 53, 5155 (2010);<br></p>

<p>Applications 3,4-DIHYDRO-2H-PYRIDO[1,2-A]PYRIMIDIN-2-ONE (cas# 5439-14-5) is a useful research chemical.<br></p>

<p>Applications 6-Dimethylaminopurine-9-riboside (cas# 2620-62-4) is a compound useful in organic synthesis.<br>References Elion, G.B., et al.: JACS, 74, 411-414 (1952), Kelley, J.L., et al.: J. Med. Chem., 32, 1020-1024 (1989)<br></p>

<p>Applications 1,3-Diiminoisoindoline is a useful compound in the production of colouring compositions. Dyes and metabolites.<br>References Matsumoto, T., et al.: PCT Int. Appl. (2020), WO 2020218262 A1<br></p>

<p>Applications 6-Chloropurine-9-(2,3-isopropylidene-β-D-ribofuranoside) (cas# 39824-26-5) is a compound useful in organic synthesis.<br></p>

<p>Applications 6-Fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (cas# 117685-48-0) is a useful research chemical.<br></p>

<p>Applications Tricyclene, is one of the main constituent of many essential oils having antioxidant activities.<br>References Tamta, A., et al.: Cogent Chemistry, Vol.2, issue1 (2016);<br></p>

<p>Applications 6,7-Dimethoxyisoquinoline is used as an organocatalyst in the chemoselective O-tert-butoxycarbonylation of phenols.<br>References Saito, Yukako, et al.: Tetrahedron Let., 51(52), 6915-6917 (2010)<br></p>

<p>Applications 4-NITROQUINOLINE N-OXIDE (cas# 56-57-5) is a useful research chemical.<br></p>

<p>Applications 2,2':6',2''-Terpyridine (cas# 1148-79-4) is a useful research chemical.<br></p>

<p>Applications Indole-3-acetamide is a compound that is converted to indole-3-acetic acid by indole-3-acetamide hydrolase in auxin biosynthesis in plants.<br>References Mano, Y., et al.: J. Exp. Bot., 61, 25 (2010)<br></p>

<p>Applications Indole-3-pyruvic Acid is a compound involved in the biosynthesis of Indole-3-acetic acid, a plant hormone which plays important roles in regulating growth and responses to environmental changes.<br>References Kong, W., et al.: Plant Cell Physiol, 56, 715-726 (2015)<br></p>

<p>Applications 2-Butoxyquinoline-4-carboxylic Acid is used in the organic synthesis of o-(β-diethylaminoethyl)cinchoninaldoxime with local anesthetic activity<br>References Rossi, S., et al.: Farmaco, Edizione Scientifica, 34, 486 (1979)<br></p>

<p>Applications 6-(gamma,gamma-Dimethylallylamino)purine riboside hemihydrate<br></p>

<p>Applications Indazolone derivative.<br></p>

<p>Applications Used in synthesis of 3-amino-5H-pyrido[4,3-b]indoles, carcinogenic .gamma.-carbolines.<br>References Akimoto, H., et al.: Bull. Chem. Soc. Jpn., 58, 123 (1985),<br></p>

<p>Stability Light Sensitive<br>Applications 5,6-Dibromo-1,10,11,12,13,13-hexachloro-11-tricyclo[8.2.1.02,9]tridecene is a flame retardant and a standard for environmental testing and research.<br>References EPA. Method 1668, (EPA 821-R-00-002) (1999); Dodson, R. E., et al.: Environ. Sci. Technol. 51, 4860 (2017)<br></p>

<p>Applications trans-Indole-3-acrylic Acid is a regent used as a matrix for MALDI-TOF mass spectroscopy in order to characterize polyphenols.<br>References Madrigal-Carballo, S., et al.: Int Food Res J, 20, 2023-2034 (2013)<br></p>

<p>Impurity Famciclovir USP Related Compound F<br>Applications Famciclovir USP Related Compound F<br></p>

<p>Stability Volatile<br>Applications 1,​1'-​Bicyclopentyl along with butanal mixtures are used to produce high density aviation fuel.<br>References Yang, J., et al.: Ind. Eng. Chem. Res., 54, 11825-11837 (2015)<br></p>

<p>Applications 1,2,3,4-tetrahydro-1,2-dimethyl-4,8-isoquinolinediol, is a Tetrahydroisoquinoline derivative, that can be used for the synthesis of pharmaceutical drugs, containing tetrahydroisoquinoline skeleton.<br></p>

<p>Applications Ethyl Indole-3-acetate is a compound used in the synthesis of 9H-Pyrrolo[1,2-α]Indoles via Michael Addition-Condensation with α,β-Unsaturated Ketimines.<br>References Zhang, M., et al.: J. Heterocyclic Chem. (2016)<br></p>

<p>Applications Pyridoxamine Dihydrochloride (cas# 524-36-7) is a compound useful in organic synthesis.<br></p>

<p>Applications 5,6,7,8-Tetrahydroquinoline (cas# 10500-57-9) is a useful research chemical.<br></p>

<p>Applications 2-azaspiro[4.5]decane-1,3-dione (cas# 1197-80-4) is related to gabapentin (G117250).<br></p>

<p>Applications 1,​2-​Dihydro-​2-​oxo-4-​quinolinecarboxylic Acid is a chemical constituent of vinegar Schisandra chinensis and is used as a indicator reagent in marking security documents.<br>References Chen, P., et al.: Zhongyaocai, 34, 1728 (2011); Kuryatnikov, A.B., et al.: Russ., RU 2581882 C1 20160420 (2016)<br></p>

<p>Applications Purine (cas# 120-73-0) is a useful research chemical.<br></p>

<p>Applications 1-Phenanthrol-d9 has been used as a reactant for the preparation of stable isotope-labeled internal standards of PAH metabolites from urine of smokers and nonsmokers.<br>References Jacob, P. III, et. al.: Anal. Chem., 79, 587 (2007)<br></p>

<p>Applications 3-Mercaptoindole (cas# 480-94-4) is a compound useful in organic synthesis.<br>References Harris, R.L.N.: Tetrahedron Letters, 51, 4465 (1969)<br></p>

<p>Applications Indoleacetic Acid is the most common and naturally occuring plant hormone in the auxin class of hormones. It effects cell elongation, cell division as well as plant growth and development.<br></p>

<p>Applications This compound has estrogenic activity. It exhibits bright blue fluorescence in neutral or acid solution, and greenish-yellow fluorescence in strong alkali solution.<br>References Wolfbeis, O.S. &amp; K. Schaffner: Photochem. Photobiol., 32, 143(1980), Bickoff et al.: J.Am. Chem Soc. 80, 3969 (1958)<br></p>

<p>Applications Halquinol is an antimicrobial compound belonging to the group of hydroxyl-quinolines indicated for use in poultry and swine. It depresses the activity of the gastro-intestinal tract, causing longer transit time of feed through the intestine, thereby enhancing digestion and absorption of nutrients. It increases weight gain and improve feed conversionprevent and control nonspecific diarrhea or wet dropping in farming animals.<br>References Costa, M. et al.: PLoS One, Vol. 12, (2017);<br></p>

<p>Applications 1-Ethyl-2,3,3-trimethylindolenium-5-sulfonate (cas# 146368-07-2) is a compound useful in organic synthesis.<br></p>

<p>Applications Methyl indole-3-carboxylate is a reagent in the preaparation of oncrasin-1 derivatives which is a novel inhibitor of the C-terminal domain of RNA polymerase II.<br>References Wu, S., et al.: J. Med. Chem., 54, 2668 (2011);<br></p>

<p>Applications 3-Bicyclo[3.2.1]octanone is used as a reactant in the synthesis of polycyclic acid derivatives as selective inhibitors of human 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD-1).<br>References Ye, X., et. al.: Bioorg. Med. Chem. Lett., 21, 6699 (2011)<br></p>

<p>Applications A chelating agent, forming complexes with most metal ions.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References El-Didamony, A., et al.: Drug Test. Anal., 2, 122 (2010), Chan, A., et al.: J. Med. Chem., 53, 3086 (2010), Ehrman, T., et al.: Bioorg. Med. Chem., 18, 2204 (2010),<br></p>

<p>Applications 5,6-Dihydroxyindole is an intermediate in melanogenesis, the production of melanin which is found in our skin, eyes, hair, and inner ear.<br>References S. Ito., et al.: Photochem. Photobiol., 84, 582-92 (2008);<br></p>