Otros inhibidores

Intermediates and Building Blocks - Nucleoside base, Electrophile; Heterocyclic Compounds - Pyridine; Scaffolds and Templates

SB-408124 Hydrochloride is a non-peptide OX1 receptor antagonist(Ki of 57 nM and 27 nM in both whole cell and membrane, respectively).

<p>2-Amino-6-chloro-9-(2-O-acetyl-5-O-benzoyl-3-O-methyl-β-D-ribofuranosyl)-9H-purine is a useful organic compound for research related to life sciences and the</p>

AVE 0991, a nonpeptide, oral Mas agonist, binds [125I]-Ang-(1-7) with IC50 of 21±35 nM.

Glycoprotein VI (GPVI) is a 63 kDa platelet/megakaryocyte-specific type I transmembrane glycoprotein of the immunoglobulin superfamily that is an important

HGFR/c-Met Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

De(5-carboxamide)oxcarbazepine is used for organic synthesis.

Hoechst 33342 analog 2 trihydrochloride is an analog of Hoechst 33342 which is a DNA minor groove binder.

Bromo-PEG2-C2-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules.

GFR Alpha-1/GFRA1 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.

2-(4-Chlorophenyl)naphtho[2,3-d]oxazole-4,9-dione is a Heterocyclic Compound and can be used in anticancer and antimicrobial studies.

KIR2DL3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.

TOOS is a novel highly water-soluble aniline derivative and is widely used in diagnostic tests and biochemical tests.

exo BCN-O-PNB is a alkyl/ether-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules.

Bis-Tos-PEG6 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules.

Mal-amido-PEG6-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules.

4-(6-Methyl-1,2,4,5-tetrazin-3-yl)phenol is an alkyl chain-derived PROTAC linker employed for the synthesis of PROTACs[1].

KIR2DL3 (2DL3, formerly NKAT2, designated CD158b2) is a 341 amino acid (aa) type I transmembrane glycoprotein that belongs to the human killer cell Ig‑like

Amino-PEG1-C2-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules.

Bromo-PEG2-alcohol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules.

BnO-PEG5-OH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules.

Amine oxidase copper-containing 1 (AOC1; formerly known as amiloride-binding protein 1) is a secreted glycoprotein that catalyzes the degradation of putrescine

3-(2-Pyridyldithio)propanoic Acid is an alkyl chain-derived PROTAC linker applicable for synthesizing PROTACs[1].

Tos-PEG8-Tos is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules.

4,4'-Bis(4-aminophenoxy)biphenyl is a monomer for polyimide production.

15-Acetyl-deoxynivalenol is a highly toxic trichothecene found in cereals and exhibits toxicity to HepG2 cells.

TSLPR Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag.

LEPR Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-10His tag.

GNRH2 (Gonadotropin-Releasing Hormone 2) is a Protein Coding gene.

BnO-PEG4-OH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules.

PCSK9 inhibitor, prevents LDL receptor binding, enhances LDL uptake, IC50 = 0.8 μM. Effective in HepG2 cells.

<p>C.I. Direct Black 17 is a compound of dye.</p>

C.I. 20195 is a brown dye.

AAPH: water-soluble azo, generates free radicals, used in lipid peroxidation studies, and antioxidation tests. Half-life ~175h at 37°C, pH neutral.

BDCA-2 Protein, Cynomolgus, Recombinant (mFc) is expressed in HEK293 mammalian cells with N-mFc tag.

C.I. Basic Orange 22 is a basic orange dye.

IGFLR1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.

Bromo-PEG1-C2-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules.

Rift Valley fever virus (RVFV) (strain MP12) glycoprotein/G2 Protein (His) is expressed in Baculovirus insect cells with His tag.

<p>CLEC14A is a single-pass transmembrane glycoprotein belonging to the vascular expressed C-type lectin family.</p>

LIMPII/SR-B2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

EPOR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

Varicella-zoster virus (VZV) (strain Oka vaccine) gH & gL Heterodimer Protein is expressed in CHO mammalian cells. The predicted molecular weight is 85.17 kDa.

Prolactin Receptor Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag.

<p>The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed by tumours, and mediates proliferation and apoptosis</p>

HGFR/c-Met Protein, Human, Recombinant (aa 956-1390, His & GST) is expressed in Baculovirus insect cells with His and GST tag.

2-Ethylpentanoic acid is a biologically active reagent that can be used in biochemical experiments.

Varicella-zoster virus (VZV) is a highly fusogenic virus, but the degree of fusion is dependent on the cell substrate in which the virus is propagated.

EphA7 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag.

EphA1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins.

<p>Benzyl-PEG4-Ots is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules.</p>

CNTFR Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag.

<p>Breast cancer (BC) is the most common cancer in women and the second leading cause of their cancer death.</p>

Chikungunya virus (CHIKV) (strain SL-CK1) E2/Envelope 2 Protein (His) is expressed in Baculovirus insect cells with His tag.

CSF1R Protein (Met1-Glu512), Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

Nucleosides and Reagents - Fluoro-modified nucleoside; pyridine nucleoside

BDCA-2 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag.

LILRA2/CD85h/ILT1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

LIFR Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag.

Ethyl (S)-2-benzoylpyrrolidine-1-carboxylate bolongs toIntermediates and Building Blocks - Others; Fine Chemical.

FOLR2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag.

<p>CLEC4A3 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.</p>

Methyl 4-Hydroxyphenylacetate has potent inhibitory activity against tobacco mosaic virus (TMV).

<p>Noggin is an antagonist of bone morphogenetic proteins (BMP), being indispensable for certain developmental events.Noggin expression positively correlated with</p>

Monkeypox Virus (MPXV) A33R Protein (His & GST) is expressed in E. coli expression system with His and GST tag. The predicted molecular weight is 44.07 kDa.

<p>Anti-abscisic acid Antibody (6P95) is a Mouse antibody targeting abscisic acid. Anti-abscisic acid Antibody (6P95) can be used in ELISA.</p>

TSLP Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

EphA2 Protein, Human, Recombinant (aa 585-976, His & GST) is expressed in Baculovirus insect cells with His and GST tag.

Osteopontin Protein, Human, Recombinant (aa 17-166, His) is expressed in HEK293 mammalian cells with His tag.

C-type lectin domain family 3 member A (CLEC3A) is a poorly characterized protein belonging to the superfamily of C-type lectins.

8-Methylnonyl nonanoate is a thickener.

The netrin-1 receptor Uncoordinated Phenotype-5A, or UNC5A, plays an important role in predicting response to DNA damage induced by chemotherapeutic drug and

<p>EPO/Erythropoietin Protein, Human, Recombinant (CHO) is expressed in CHO Cells. The accession number is P01588.</p>

<p>Anti-Clenbuterol Antibody (8E543) is a Mouse antibody targeting Clenbuterol. Anti-Clenbuterol Antibody (8E543) can be used in ELISA.</p>

<p>Anti-Ractopamine Antibody (1W845) is a Mouse antibody targeting Ractopamine. Anti-Ractopamine Antibody (1W845) can be used in ELISA.</p>

<p>Anti-Kanamycin Antibody (3J6) is a Mouse antibody targeting Kanamycin. Anti-Kanamycin Antibody (3J6) can be used in ELISA.</p>

<p>Girard's Reagent P, a cationic hydrazine compound, serves as a derivatization agent for the quantification of glycans, oxysterols, and 5-methylcytosine</p>

Anti-CD63 Antibody (4S283) is a Mouse antibody targeting CD63. Anti-CD63 Antibody (4S283) can be used in ELISA, WB, IHC, IF, FCM.

<p>MIF Protein, Human, Recombinant is expressed in E. coli. The accession number is P14174.</p>

<p>Anti-Chenodeoxycholic acid Antibody (2K943) is a Mouse antibody targeting Chenodeoxycholic acid. Anti-Chenodeoxycholic acid Antibody (2K943) can be used in ELISA.</p>

<p>Anti-Cortisol Antibody (6S645) is a Mouse antibody targeting Cortisol. Anti-Cortisol Antibody (6S645) can be used in ELISA.</p>

Expression System: E. coli<br>Length: 21-71, Full Length of Mature Protein<br>Activity: Cell Activity

(2R)-Octyl-α-hydroxyglutarate ((2R)-Octyl-2-HG) is a D-isomer 2-Hydroxyglutarate modified form.

<p>Diisobutyl adipate is a diester. It is used in disinfectants.</p>

<p>Sorbitan monostearate is an ester of stearic acid and sorbitan (a sorbitol derivative), it is also sometimes referred to as a synthetic wax.</p>

Zanamivir hydrate is neuraminidase inhibitors. It is used worldwide for the treatment and prophylaxis of influenza caused by influenza A and B viruses.

<p>Arachidoyl ethanolamide, a saturated fatty acyl ethanolamide lacking classical (CB1/CB2) activity, plays a role in a complex system comprising central cannabinoid (CB1), peripheral cannabinoid (CB2), and non-CB receptor-mediated pharmacology. This system has paved the way for extensive research in diverse fields such as memory, weight loss and appetite, neurodegeneration, tumor surveillance, analgesia, and inflammation. Unlike other compounds, Arachidoyl ethanolamide does not bind to the murine CB1 receptor nor does it compete with anandamide for the fatty acid amide hydrolase, the endocannabinoid hydrolytic enzyme. The non-CB receptor-mediated actions of saturated ethanolamides like Arachidoyl ethanolamide are currently under investigation.</p>

5’-O-DMTr-2’-OMe-5MeU-P-methyl phosphonamidite; 5’-O-DMTr-2’-O-methyl-5-methyluridine-3’-O-(P-methyl-N,N-diisopropylamino) phosphonamidite is a useful organic

Epstein-Barr virus (EBV) (strain B95-8) gH & gL Heterodimer Protein (His & Flag) is expressed in HEK293 mammalian cells with His and Flag tag.

SEMA6A, the first identified class 6 semaphorin, is contributed to regulate vascular development and adult angiogenesis.

COLEC11 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag.

Fibronectin is a high-molecular weight glycoprotein of the extracellular matrix that binds to membrane-spanning receptor proteins called integrins.

LRP-6 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

Albumin Protein, Human, Recombinant, Biotinylated is expressed in yeast. The predicted molecular weight is 66.5 kDa and the accession number is P02768-1.

Epiphycan Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

Mouse Metalloproteinase inhibitor 2(TIMP-2), belongs to a family of proteins that regulate the activation and proteolytic activity of matrix metalloproteinases

Cyclin A1 is a member of the highly conserved cyclin family that is characterized by a dramatic periodicity in protein abundance, and belongs to the A-type

Human Natriuretic peptides B acts as a cardiac hormone; it is associated with many biological actions, such as diuresis, natriuresis, vasorelaxation, which

HNT/NTM Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

ERMAP Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag.

Ubiquitin-Associated Protein 1 (UBAP1) belongs to the UBA domain family.

Proteoglycan 3, also known as Eosinophil major basic protein homolog, Prepro-major basic protein homolog, PRG3 and MBPH, contains one C-type lectin domain.

INHCA, official full name is inhibitor of carbonic anhydrase, which is a member of the transferrin gene family.

N6-Ethyl-2'-beta-C-ethynyl adenosine is a Nucleoside Derivative - 2'-Modified nucleoside, 6-Modified purine nucleoside.

ATP-binding cassette sub-family B member 5(ABCB5) is a plasma membrane-spanning protein.

Serpin A1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

PAX8 gene is a member of the paired box (PAX) family of transcription factors.

Apoptosis-Inducing Factor 1, Mitochondrial (AIFM1) is a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial

DEFB127 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.

Annexin V/ANXA5 Protein, Human, Recombinant, Biotinylated is expressed in E.

<p>Growth arrest-specific 6, also known as Gas6, is a human gene encoding the Gas6 protein, which was originally found to be upregulated in growth-arrested</p>

Heat shock protein beta-1 (HSPB1, also known as HSP27) is a small heat shock protein involved in many cellular processes and reportedly protects cells against

S100A9 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag.

S100B Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.

Bactericidal/permeability-increasing protein is a member of the BPI/LBP/Plunc superfamily and BPI/LBP family.

Copper homeostasis protein cutC homolog, also known as CGI-32 and CUTC, is a cytoplasm and nucleus protein which belongs to theCutC family.

VSIG4, a B7 family-related protein, is a negative regulator of T cell activation.T cell activation by APCs is positively and negatively regulated by members of

NFYA Protein, Human, Recombinant is expressed in E.

Serpin B12 is a member of the serpin family.