Señalización citoesquelética
Los inhibidores de la señalización del citoesqueleto son compuestos que interrumpen las vías de señalización que regulan el citoesqueleto, crucial para la forma celular, la motilidad, la división y el transporte intracelular. Estos inhibidores se utilizan para estudiar la dinámica de las proteínas del citoesqueleto, como la actina y la tubulina, y su papel en procesos como la migración celular, la adhesión y la metástasis del cáncer. Los inhibidores de la señalización del citoesqueleto son valiosos en la investigación sobre biología celular, cáncer y neurobiología. En CymitQuimica, ofrecemos una amplia gama de inhibidores de la señalización del citoesqueleto de alta calidad para apoyar su investigación en estas áreas.
Se han encontrado 1472 productos de "Señalización citoesquelética"
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Abituzumab
CAS:Abituzumab (DI17E6) is a humanized monoclonal antibody targeting integrin alphaV, exhibiting anti-cancer activity and can be used in prostate cancer research.Pureza:>95%Forma y color:LiquidPamidronate Disodium
CAS:Pamidronate Disodium (CGP 23339A), a nitrogen-containing bisphosphonate, can help to strengthen bones.Fórmula:C3H9NNa2O7P2Pureza:99.86% - 99.93%Forma y color:White CrystalsPeso molecular:279.03Otelixizumab
CAS:<p>Otelixizumab (ChAglyCD3) is a chimeric monoclonal antibody targeting CD3, used in research on Type 1 diabetes and autoimmune diseases.</p>Pureza:>95%Forma y color:LiquidArimoclomol maleate
CAS:<p>Arimoclomol maleate (BRX-220) (BRX-220) is a heat shock protein (HSP) co-inducer.</p>Fórmula:C18H24ClN3O7Pureza:99.44% - 99.98%Forma y color:SolidPeso molecular:429.85GRP78-IN-3
CAS:<p>GRP78-IN-3: Potent Hsp70 blocker, selective Grp78 (HSPA5) inhib., IC50 0.59 μM, 7x more vs HspA9, 20x vs HspA2.</p>Fórmula:C17H18N4O2SPureza:99.11%Forma y color:SoildPeso molecular:342.42Abrilumab
CAS:Abrilumab (MEDI-7183) is a fully human monoclonal antibody against α4β7 that inhibits the α4β7 integrin.Pureza:98.5% (SDS-PAGE); 99% (SEC-HPLC) - 98.5% (SDS-PAGE); 99% (SEC-HPLC)Forma y color:Liquid(+)-Blebbistatin
CAS:<p>(+)-Blebbistatin is the inactive enantiomer of (–)-Blebbistatin. (–)-Blebbistatin is a selective myosin II ATPase inhibitor.</p>Fórmula:C18H16N2O2Pureza:99.88%Forma y color:SolidPeso molecular:292.33Dasatinib monohydrate
CAS:Dasatinib monohydrate, an oral SRC-kinase inhibitor, counters imatinib-resistant chronic myeloid leukemia.Fórmula:C22H28ClN7O3SPureza:99.68% - >99.99%Forma y color:SolidPeso molecular:506.03Bisindolylmaleimide VIII acetate
CAS:Bisindolylmaleimide VIII acetate is a selective PKC inhibitor with an IC50 of 158 nM in rat brain and varying IC50s for different PKC isoforms.Fórmula:C26H26N4O4Pureza:99.27%Forma y color:SolidPeso molecular:458.51Rifabutin
CAS:Rifabutin (LM-427), a semisynthetic ansamycin, blocks bacterial RNA synthesis by inhibiting RNA polymerase.Fórmula:C46H62N4O11Pureza:98.87% - 99.7%Forma y color:Red-Violet Crystalline PowderPeso molecular:847Xentuzumab
CAS:Xentuzumab (BI836845) is a recombinant monoclonal antibody to humanised IGF ligand that inhibits AKT activation and can be used to study solid tumours.Pureza:95% - > 95%Forma y color:LiquidPeso molecular:143.7 kDaPKC β pseudosubstrate acetate
PKC β pseudosubstrate acetate (PKC β pseudosubstrate acetate (172308-76-8 Free base)) is a selective cell-permeable inhibitor of PKC.Pureza:95.42%Forma y color:SoildBNC105
CAS:BNC105 is a tubulin polymerization inhibitor. It has potent antiproliferative and tumor vascular disrupting properties.Fórmula:C20H20O7Pureza:96.57%Forma y color:SolidPeso molecular:372.37SGC-AAK1-1
CAS:<p>SGC-AAK1-1 is a potent and selective inhibitor of AAK1 (AP2 associated kinase 1) (IC50 of 270 nM and a Ki of 9 nM),and is a chemical probe.</p>Fórmula:C21H25N5O3SPureza:99.68%Forma y color:SolidPeso molecular:427.52Fluocinolone (Acetonide)
CAS:Fluocinolone Acetonide (Flucort-N) is a glucocorticoid derivative used topically in the treatment of various skin disorders.Fórmula:C24H30F2O6Pureza:99.29% - 99.82%Forma y color:Crystals From Acetone & Hexane SolidPeso molecular:452.49Bepranemab
CAS:<p>Bepranemab (UCB 0107) - humanized IgG4 monoclonal antibody targeting tau (235-250) for Alzheimer's research.</p>Pureza:99% (SDS-PAGE); 96.8% (SEC-HPLC) - 99% (SDS-PAGE); 96.8% (SEC-HPLC)Forma y color:LiquidAdropin (34-76) (human, mouse, rat)
CAS:Adropin (34-76) (human, mouse, rat) is a peptide that attenuates liver fibrosis and insulin resistance. Cost-effective and quality-assured.Fórmula:C190H293N55O68S2Pureza:94.23% - 99.95%Forma y color:SolidPeso molecular:4499.82Tidutamab
CAS:<p>Tidutamab (XmAb-18087) is a humanized bispecific antibody targeting the growth inhibitory receptor 2 (SSTR2) and T cell binding domain (CD3).</p>Pureza:97.9% (SDS-PAGE); 97.8% (SEC-HPLC) - 97.9% (SDS-PAGE); 97.8% (SEC-HPLC)Forma y color:LiquidDonanemab
CAS:<p>Donanemab (LY3002813), a humanized IgG1 antibody, targets N-terminal Aβ for potential early Alzheimer's research.</p>Pureza:95%Forma y color:LiquidGNE 2861
CAS:GNE 2861 inhibits PAK4, PAK5, and PAK6 (IC50s: 7.5, 36, 126 nM, respectively). GNE 2861 is a PAK inhibitor that shows group II selectivity.Fórmula:C22H26N6O2Pureza:97.03%Forma y color:SolidPeso molecular:406.48Col003
CAS:Col003 is a selective and potent inhibitor of Hsp47 and competitively binds to the collagen-binding site on Hsp47 (IC50: 1.8 μM).Fórmula:C14H11NO4Pureza:99.03% - 99.96%Forma y color:SolidPeso molecular:257.24LXH254
CAS:LXH254 is a B/C RAF inhibitor with IC50 values of 0.2 nM and 0.07 nM for inhibiting BRAF and CRAF.Cost-effective and quality-assured.Fórmula:C25H25F3N4O4Pureza:98.3% - 99.92%Forma y color:SolidPeso molecular:502.49Ethoxyquin
CAS:<p>Ethoxyquin (Santoflex) is an antioxidant used in animal feeds.</p>Fórmula:C14H19NOPureza:97.15% - 98.73%Forma y color:Yellow Liquid Mercaptan-Like Odor (Ntp 1992)Peso molecular:217.31BOS-172722
CAS:BOS-172722 is an inhibitor of monopolar spindle 1 (MPS1) checkpoint(IC50 of 2 nM).Fórmula:C24H30N8OPureza:99.37%Forma y color:SolidPeso molecular:446.55AC 7739
CAS:<p>AC 7739 is a microtubule protein binding agent with anticancer and antitumor activity that inhibits advanced solid tumors and in situ transplanted tumors.</p>Fórmula:C18H22ClNO4Pureza:99.38% - 99.55%Forma y color:SoildPeso molecular:351.83Akt3 degrader 1
CAS:Akt3 degrader 1 counters Osimertinib resistance in NSCLC, inhibits cell growth, and reduces mouse tumors.Fórmula:C53H72N8O4Pureza:98.12% - 99.02%Forma y color:SolidPeso molecular:885.19Bosutinib
CAS:Bosutinib (SKI-606) is a synthetic quinolone derivative and dual kinase inhibitor that targets both Abl (IC50: 1 nM) and Src (IC50: 1.2 nM) kinases.Fórmula:C26H29Cl2N5O3Pureza:98.98% - 99.9%Forma y color:Yellowish-Orange Or Pink To Brownish Solid Solid PowderPeso molecular:530.45Tadocizumab
CAS:<p>Tadocizumab (C4G1) is a humanized monoclonal antibody targeting integrin αIIbβ3 with antiplatelet and antithrombotic effects.</p>Pureza:97.1% (SDS-PAGE); 97.2% (SEC-HPLC) - 97.1% (SDS-PAGE); 97.2% (SEC-HPLC)Forma y color:LiquidA-3 hydrochloride
CAS:<p>A-3 hydrochloride: potent, reversible kinase antagonist; permeable; inhibits PKC, CKI, PKA, CKII, MLCK; Ki: 4.3-80 μM.</p>Fórmula:C12H14Cl2N2O2SPureza:99.32%Forma y color:SolidPeso molecular:321.22Spiperone
CAS:Spiperone (Spiropitan) is a spiro butyrophenone analog similar to HALOPERIDOL and other related compounds.Fórmula:C23H26FN3O2Pureza:99.34% - 99.91%Forma y color:SolidPeso molecular:395.47TINK-IN-1
CAS:<p>TINK-IN-1 is a selective and potent TNIK inhibitor (IC50: 8 nM).TINK-IN-1 inhibits colorectal cancer cell viability and can be used to study mental retardation.</p>Fórmula:C24H24N4O3Pureza:99.4%Forma y color:SoildPeso molecular:416.47Teplizumab
CAS:<p>Teplizumab (MGA-031) is a humanized monoclonal antibody against CD3 that slows the loss of beta cell function.Teplizumab is used to treat type 1 diabetes.</p>Pureza:SDS-PAGE:95.8%;SEC-HPLC:99.7%Forma y color:LiquidPeso molecular:145.79 kDaTilavonemab
CAS:Tilavonemab (ABBV-8E12), a humanized anti-tau antibody, halts tau uptake in neurons and may help with Alzheimer's research.Pureza:95.2% (SDS-PAGE); 96.6% (SEC-HPLC) - 95.2% (SDS-PAGE); 96.6% (SEC-HPLC)Forma y color:LiquidCC-99677
CAS:<p>CC-99677 (Gamcemetinib) is a MK2 inhibitor targeting autoimmune diseases; potent in rat assays with IC50=156.3 nM & EC50=89 nM.</p>Fórmula:C22H20ClN5O3SPureza:99.59%Forma y color:SolidPeso molecular:469.94Glofitamab
CAS:<p>Glofitamab (RO7082859), a bivalent antibody, targets CD20 on B-cells to aid T cell attack in relapsed/refractory lymphomas.</p>Pureza:SDS-PAGE:98.2%;SEC-HPLC:98.0%Forma y color:LiquidPeso molecular:170.37 kDaTalquetamab
CAS:Talquetamab (JNJ-64407564) is a T-cell retargeting GPRC5D bispecific antibody with antitumor activity for the treatment of multiple myeloma.Forma y color:LiquidPeso molecular:144.59 kDaCibisatamab
CAS:Cibisatamab, a T-cell bispecific antibody, targets CEA on cancer cells and CD3 on T-cells, inducing T-cell-mediated tumor cell killing.Pureza:SDS-PAGE:99.1%;SEC-HPLC:96.5%Forma y color:LiquidPeso molecular:191.1 kDaN-Desmethyltamoxifen hydrochloride
CAS:<p>N-Desmethyltamoxifen hydrochloride is the major tamoxifen metabolite in humans.</p>Fórmula:C25H28ClNOPureza:99.15%Forma y color:SolidPeso molecular:393.95Tubulin inhibitor 6
CAS:Tubulin inhibitor 6 (iHAP1) is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines.Fórmula:C20H14ClNO2SPureza:99.05%Forma y color:SolidPeso molecular:367.85Vantictumab
CAS:Vantictumab (OMP-18R5) is a humanized anti-FZD1/2/5/7/8 monoclonal antibody that inhibits Wnt pathway signaling.Pureza:99% (SDS-PAGE); 97.7% (SEC-HPLC) - 99% (SDS-PAGE); 97.7% (SEC-HPLC)Forma y color:LiquidDarifenacin hydrobromide
CAS:<p>Darifenacin hydrobromide (UK-88525) is a selective muscarinic receptor antagonist used to treat urinary incontinence and overactive bladder syndrome.</p>Fórmula:C28H31BrN2O2Pureza:99.75% - >99.99%Forma y color:SolidPeso molecular:505.45CK-666
CAS:<p>CK-666 inhibits Arp2/3 complex, blocking Arp2/3 activation and actin filament formation.</p>Fórmula:C18H17FN2OPureza:99.93%Forma y color:SolidPeso molecular:296.347-Aminocephalosporanic acid
CAS:7-Aminocephalosporanic acid (7-ACA) is used for synthesis of cephalosporin antibiotics and intermediates.Fórmula:C10H12N2O5SPureza:91.05%Forma y color:White Solid PowderPeso molecular:272.28NVS-PAK1-1
CAS:NVS-PAK1-1 is an effective and selective allosteric PAK1 inhibitor (IC50: 5 nM).Fórmula:C23H25ClF3N5OPureza:99.35%Forma y color:SolidPeso molecular:479.93Delcasertib
CAS:<p>Delcasertib (KAI-9803) is a potent and selective inhibitor of δ-protein kinase C (δPKC).</p>Fórmula:C120H199N45O34S2Pureza:99.96%Forma y color:SolidPeso molecular:2880.282,3-Butanedione 2-Monoxime
CAS:2,3-Butanedione 2-Monoxime (Diacetyl monoxime) is an inhibitor of skeletal and cardiac muscle contraction.Fórmula:C4H7NO2Pureza:98.62%Forma y color:Physical Description Cream-Colored Powder (Ntp 1992)Peso molecular:101.1N-Desmethyl imatinib
CAS:N-Desmethyl imatinib (Imatinib metabolite N-Desmethyl imatinib) is a metabolite of Imatinib, which is a multi-target inhibitor of c-Kit, v-Abl, and PDGFR.Fórmula:C28H29N7OPureza:98.60%Forma y color:Off-White To Pale-Yellow SolidPeso molecular:479.58Lyn-IN-1
CAS:Lyn-IN-1 (Bafetinib analog) is a selective and potent dual inhibitor of Bcr-Abl and LynFórmula:C30H31F3N8OPureza:97% - 98.02%Forma y color:SolidPeso molecular:576.62Entasobulin
CAS:Entasobulin is an inhibitor of β-tubulin polymerization. It has a potential anticancer activity.Fórmula:C26H18ClN3O2Pureza:98.40%Forma y color:SolidPeso molecular:439.89Nilotinib
CAS:<p>Nilotinib (AMN107) is a Bcr-Abl tyrosine kinase inhibitor. Nilotinib has antitumor activity and may be used in CML. Cost-effective and quality-assured.</p>Fórmula:C28H22F3N7OPureza:99.89% - >99.99%Forma y color:Off-White SolidPeso molecular:529.52Vedolizumab
CAS:<p>Vedolizumab is a humanized monoclonal antibody that targets the α4β7 integrin for the treatment of Crohn's disease and ulcerative colitis.</p>Pureza:SDS-PAGE:98.4%;SEC-HPLC:99.1%Forma y color:LiquidPeso molecular:146.80 kDaElarofiban TFA
CAS:Elarofiban TFA (RWJ-53308 TFA) is a novel and orally active and selective GPIIb/IIIa antagonist for the study of cardiovascular disease.Fórmula:C26H34F6N4O8Pureza:99.08%Forma y color:SoildPeso molecular:644.56AKE-72
CAS:<p>AKE-72 is a Pan-BCR-ABL inhibitor with anti-leukemic activity.AKE-72 inhibits the proliferation of Ba/F3 cells expressing natural BCR-ABL or its T315I mutant.</p>Fórmula:C30H29F3N6OPureza:98.3%Forma y color:SoildPeso molecular:546.59IPI-493
CAS:IPI-493 is a bioactive chemical.Fórmula:C28H39N3O8Pureza:>99.99%Forma y color:SolidPeso molecular:545.62Mitoxantrone dihydrochloride
CAS:<p>Mitoxantrone dihydrochloride (NSC-301739) is an anthracenedione antibiotic with antineoplastic activity. Mitoxantrone is a type II topoisomerase inhibitor.</p>Fórmula:C22H30Cl2N4O6Pureza:97.05% - >99.99%Forma y color:Blue-Black Solid From Water Ethanol SolidPeso molecular:517.4Bersanlimab
CAS:Bersanlimab (BI-505) is a fully human monoclonal antibody targeting Intercellular Adhesion Molecule-1 (ICAM-1).Bersanlimab has anticancer properties.Pureza:> 95% - > 95%Forma y color:LiquidPeso molecular:144.22 kDaRecilisib
CAS:Recilisib (ON 01210) is a radioprotectant,can activate AKT, PI3K activities in cells.Fórmula:C16H13ClO4SPureza:98.85% - 98.96%Forma y color:SolidPeso molecular:336.79Arg-Gly-Asp-Ser acetate
Arg-Gly-Asp-Ser acetate targets integrin, binding pro-caspase-8, -9, -3, but not -1; inhibits receptor function.Fórmula:C17H31N7O10Pureza:98.14%Forma y color:SolidPeso molecular:493.47Verubulin hydrochloride
CAS:Verubulin hydrochloride (MPC-6827 hydrochloride) is an agent of blood brain barrier permeable microtubule-disrupting, with potent and broad-spectrum cytotoxicFórmula:C17H18ClN3OPureza:98.29% - 99.77%Forma y color:SolidPeso molecular:315.8DM4
CAS:DM4 (Ravtansine) can be used in the preparation of antibody drug conjugate and it is an antitubulin agent. It can inhibit cell division.Fórmula:C38H54ClN3O10SPureza:98.15%Forma y color:SolidPeso molecular:780.37Mps1-IN-3
CAS:Mps1-IN-3 is an effective and selective inhibitor of MPS1 kinase (IC50: 50 nM).Fórmula:C26H31N7O4SPureza:99.25%Forma y color:SolidPeso molecular:537.63ADH-1 trifluoroacetate
CAS:<p>ADH-1 trifluoroacetate (Exherin trifluoroacetate) is a cyclic pentapeptide vascular-targeting agent with potential antineoplastic and antiangiogenic activities.</p>Fórmula:C24H35F3N8O8S2Pureza:90.08% - 99.17%Forma y color:SolidPeso molecular:684.71RWJ 50271
CAS:<p>RWJ 50271 inhibits LFA-1/ICAM-1 interaction with IC50 5.0 μM in HL60 cells.</p>Fórmula:C18H17F3N4O2SPureza:99.09%Forma y color:SolidPeso molecular:410.41Efalizumab
CAS:Efalizumab: humanized monoclonal antibody CD11a; modulates T cell activation/adhesion; for plaque psoriasis, psoriatic arthritis research.Pureza:SDS-PAGE:95% SEC-HPLC:98.77%Forma y color:LiquidPeso molecular:146.14 kDaImatinib Mesylate
CAS:<p>Imatinib Mesylate (STI-571) is a tyrosine kinase receptor inhibitor with antineoplastic activity (IC50s: 0.6 μM, 0.1 μM and 0.1 μM for v-Abl, c-Kit and PDGFR,</p>Fórmula:C29H31N7O·CH4SO3Pureza:98% - >99.99%Forma y color:White Crystalline PowderPeso molecular:589.71Zagotenemab
CAS:<p>Zagotenemab: humanized antibody targeting tau protein to study neurological disorders, including Alzheimer's.</p>Pureza:95% - > 95%Forma y color:LiquidPeso molecular:145.3 kDaDanicamtiv
CAS:<p>Danicamtiv (MYK-491) is an inotropic agent and it also is a selective allosteric activator of cardiac myosin.</p>Fórmula:C16H20F3N5O4SPureza:99.38%Forma y color:SolidPeso molecular:435.42Abciximab
CAS:<p>Abciximab: chimeric antibody, anti-platelet, blocks glycoprotein IIb/IIIa, vitronectin, Mac-1.</p>Pureza:SDS-PAGE:95.2%;SEC-HPLC:95.9%Forma y color:LiquidPeso molecular:95.18 kDaIMAB027
CAS:<p>Naratuximab (Anti-TSPAN26/CD37 Reference Antibody) is a humanized monoclonal antibody against CD37 that can be used to synthesize ADC compounds.</p>Pureza:97.7% (SDS-PAGE); 97.5% (SEC-HPLC) - 97.7% (SDS-PAGE); 97.5% (SEC-HPLC)Forma y color:LiquidDasatinib
CAS:<p>Dasatinib (BMS-354825) is a tyrosine kinase inhibitor that inhibits Src and Bcr-Abl (Ki=16/30 pM) and is orally active and ATP-competitive.</p>Fórmula:C22H26ClN7O2SPureza:99.59% - 99.86%Forma y color:Pale-Yellow SolidPeso molecular:488.01ATN-161 trifluoroacetate salt
CAS:<p>ATN-161 TFA salt, a new integrin α5β1 inhibitor, curbs angiogenesis, liver metastases growth, enhances survival in mice.</p>Fórmula:C25H36F3N9O10SPureza:98% - 99.98%Forma y color:SolidPeso molecular:711.67Fluorofenidone
CAS:<p>Fluorofenidone (AKF-PD) slows kidney fibrosis by inhibiting NADPH oxidase/ECM via PI3K/Akt, akin to AMR69 but less toxic with a longer half-life.</p>Fórmula:C12H10FNOPureza:99.85%Forma y color:SolidPeso molecular:203.21CMPD101
CAS:<p>CMPD101 is a membrane-permeable small-molecule inhibitor of GRK2/3 (IC50: 18 nM and 5.4 nM).</p>Fórmula:C24H21F3N6OPureza:99.01% - 99.04%Forma y color:SolidPeso molecular:466.46ATN-161 acetate
CAS:<p>ATN-161 acetate, a pentapeptide compound derived from the synergistic region of fibronectin, is an integrin-alpha5 antagonist with antitumor activity.</p>Fórmula:C25H39N9O10SPureza:98.27%Forma y color:SoildPeso molecular:657.7Mosunetuzumab
CAS:Mosunetuzumab (BCT-4465A) is an IgG1 antibody targeting CD20 & CD3, used for R/R B-NHL and refractory follicular lymphoma.Pureza:SDS-PAGE:94.4%;SEC-HPLC:96.1%Forma y color:LiquidPeso molecular:146.27 kDaAS1949490
CAS:<p>AS1949490, a selective SHIP-2 inhibitor with IC50 of 620 nM, boosts glucose metabolism by upregulating GLUT1 in L6 myotubes.</p>Fórmula:C20H18ClNO2SPureza:99.94%Forma y color:SolidPeso molecular:371.88Veltuzumab
CAS:Veltuzumab (IMMU-106) is a humanized anti-CD20 monoclonal antibody that shows anti-proliferative, apoptotic and antibody-dependent cytotoxic effects in vitro.Pureza:97.7% (SDS-PAGE); 97.9% (SEC-HPLC) - 97.7% (SDS-PAGE); 97.9% (SEC-HPLC)Forma y color:LiquidForalumab
CAS:<p>Foralumab (NI-0401) is a human anti-CD3 monoclonal antibody for the study of COVID-19 infection.</p>Pureza:96.7% (SDS-PAGE); 96.4% (SEC-HPLC) - 96.7% (SDS-PAGE); 96.4% (SEC-HPLC)Forma y color:LiquidMeclofenamic acid sodium
CAS:Meclofenamic acid sodium (Movens), a non-steroidal anti-inflammatory agent, has properties of antipyretic and antigranulation activities.Fórmula:C14H10Cl2NNaO2Pureza:98% - 98.96%Forma y color:SolidPeso molecular:318.14Orbofiban TFA
CAS:<p>Orbofiban TFA is an orally active GPIIb/IIIa platelet receptor antagonist with inhibitory effects on platelet aggregation for the study of unstable coronary</p>Fórmula:C19H24F3N5O6Pureza:97.21% - 98.72%Forma y color:SolidPeso molecular:475.42Larazotide acetate
CAS:Larazotide acetate is a synthetic peptide. It functions as a tight junction regulator and reverses leaky junctions to their normally closed state.Fórmula:C34H59N9O12Pureza:95.53% - 99.425%Forma y color:SolidPeso molecular:785.89Paprotrain
CAS:Paprotrain ((alphaZ)-alpha-(3-Pyridinylmethylene)-1H-indole-3-acetonitrile) inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 μM and a Ki of 3.36 μM.Fórmula:C16H11N3Pureza:99.91%Forma y color:SolidPeso molecular:245.28Bimosiamose
CAS:Bimosiamose has anti-inflammatory effects[1].Fórmula:C46H54O16Pureza:98%Forma y color:SolidPeso molecular:862.91SNIPER(ABL)-015
SNIPER(ABL)-015, a compound that conjugates GNF5 (ABL inhibitor) to MV-1 (IAP ligand) via a linker, effectively reduces BCR-ABL protein levels with a DC50 of 5Fórmula:C58H70F3N9O9Pureza:98%Forma y color:SolidPeso molecular:1094.23PKCiota-IN-2
CAS:PKCiota-IN-2 selectively inhibits PKC-ι (IC50=2.8nM) and also blocks PKC-α, ε (IC50s=71nM, 350nM).Fórmula:C24H21N5OPureza:98.86%Forma y color:SolidPeso molecular:395.46Myosin V-IN-1
CAS:<p>Myosin V-IN-1: potent, selective Myosin V inhibitor, Ki of 6 μM; hinders actin-activated ATPase by blocking ADP release.</p>Fórmula:C29H26N6O3SPureza:98.64% - 98.64%Forma y color:SolidPeso molecular:538.626BrCaQ-C10-TPP
<p>6BrCaQ-C10-TPP inhibits TRAP1, halts cancer cell growth (IC50=0.008-0.30µM), disrupts mitochondrial membrane.</p>Fórmula:C45H47Br2N2O3PForma y color:SolidPeso molecular:854.65MS98
CAS:<p>MS98, a specific PROTAC AKT degrader, depletes T-AKT with DC50 of 78 nM; binds AKT1, AKT2, AKT3 with Kds of 4, 140, 8.1 nM.</p>Fórmula:C58H81ClN10O7SForma y color:SolidPeso molecular:1097.86Gantofiban
CAS:Gantofiban is a glycoprotein IIb/IIIa (GP IIb/IIIa) antagonist used in the treatment of cardiovascular disease and may be used to study thrombosis.Fórmula:C21H29N5O6Pureza:99.57%Forma y color:SolidPeso molecular:447.48GRGDSP
CAS:<p>Gly-Arg-Gly-Asp-Ser-Pro (GRGDSP) is used as a soluble integrin-blocking RGD-based peptide.</p>Fórmula:C22H37N9O10Pureza:98%Forma y color:SolidPeso molecular:587.58Larazotide
CAS:<p>Larazotide: octapeptide from V. cholerae, treats Coeliac disease by inhibiting paracellular permeability.</p>Fórmula:C32H55N9O10Pureza:98%Forma y color:SolidPeso molecular:725.83PDS-0330
CAS:<p>PDS-0330, a claudin-1 inhibitor, hinders CRC growth and metastasis with micromolar affinity and promising pharmacokinetics.</p>Fórmula:C25H17N3O2SPureza:99.93%Forma y color:SoildPeso molecular:423.49Abl Cytosolic Substrate
CAS:Abl Cytosolic Substrate is a substrate for Abelson tyrosine kinase (Abl ).Fórmula:C64H101N15O16Pureza:98%Forma y color:SolidPeso molecular:1336.58Catumaxomab
CAS:<p>Catumaxomab is a rat-mouse hybrid lgG2 monoclonal and bispecific antibody that binds to the antigens CD3 and EpCAM for malignant ascites in cancer patients.</p>Pureza:95%Forma y color:LiquidhCA/Wnt/β-catenin-IN-1
<p>hCA/Wnt/β-catenin-IN-1 (Compd 15) serves as an inhibitor with selective affinity for hCA isoforms II, IX, and XII, exhibiting K i values of 33.6, 24.1, and 6.8</p>Forma y color:Odour SolidTNIK-IN-7
CAS:<p>TNIK-IN-7 is a Traf2 and Nck interacting kinase (TNIK) inhibitor with antitumor activity for the study of signaling and proliferation in colorectal cancer cells</p>Fórmula:C23H22N4O2Pureza:99.87%Forma y color:SoildPeso molecular:386.45DSPE-PEG2000-iRGD
<p>DSPE-PEG2000-iRGD is a PEG compound composed of DSPE and the αv-integrin targeting peptide (iRGD). The iRGD peptide binds to αv-integrins and subsequently undergoes proteolytic cleavage within tumors, producing CRGDK/R, which interacts with neuropilin-1. This compound is characterized by its tumor-targeting and tumor-penetrating properties, making DSPE-PEG2000-iRGD suitable for drug delivery applications.</p>Forma y color:Odour SolidZolbetuximab MMAE
Zolbetuximab MMAE (IMAB362 MMAE) is a compound targeting Claudin 18.2 (CLDN18.2) with anti-cancer activity, used in the study of gastric and pancreatic cancers.Pureza:99.19% (SEC-HPLC) - 99.4% (SEC-HPLC)Forma y color:LiquidPeso molecular:150 kDaEpothilone F
CAS:Epothilone F, an active metabolite of Epothilone D with a hydroxymethyl on thiazole, disrupts cell division, shows promise over taxanes, and is water-soluble.Fórmula:C27H41NO7SForma y color:SolidPeso molecular:523.68Foxy-5
CAS:Foxy-5 is a wnt5a peptide mimeticFórmula:C26H42N6O12S2Pureza:98%Forma y color:SolidPeso molecular:694.77
