Señalización citoesquelética
Los inhibidores de la señalización del citoesqueleto son compuestos que interrumpen las vías de señalización que regulan el citoesqueleto, crucial para la forma celular, la motilidad, la división y el transporte intracelular. Estos inhibidores se utilizan para estudiar la dinámica de las proteínas del citoesqueleto, como la actina y la tubulina, y su papel en procesos como la migración celular, la adhesión y la metástasis del cáncer. Los inhibidores de la señalización del citoesqueleto son valiosos en la investigación sobre biología celular, cáncer y neurobiología. En CymitQuimica, ofrecemos una amplia gama de inhibidores de la señalización del citoesqueleto de alta calidad para apoyar su investigación en estas áreas.
Se han encontrado 1383 productos de "Señalización citoesquelética"
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Afuresertib hydrochloride
CAS:<p>Afuresertib hydrochloride is an inhibitor of Akt kinase (Kis of 0.08/2/2.6 nM for Akt1/Akt2/Akt3 respectively)</p>Fórmula:C18H18Cl3FN4OSPureza:99.96%Forma y color:SolidPeso molecular:463.8Cyclo(RADfK)
CAS:<p>Cyclo(RADfK) is a selective α(v)β(3) integrin ligand used in neoangiogenesis research, therapy, and diagnostics; it's a control for RGD peptides.</p>Fórmula:C28H43N9O7Pureza:>99.99%Forma y color:SolidPeso molecular:617.7Trimethyloctadecylammonium bromide
CAS:<p>Trimethyloctadecylammonium bromide is an inhibitor of Dynamin I(IC50 : 1.9 μM) and also inhibits Dynamin Ⅱ.</p>Fórmula:C21H46N·BrPureza:99.09%Forma y color:Solid SolidPeso molecular:392.5E7820
CAS:<p>E7820 (ER68203-00) is an angiogenesis inhibitor by suppressing integrin a2 (a cell adhesion molecule expressed on endothelial cells).</p>Fórmula:C17H12N4O2SPureza:98.31% - 99.11%Forma y color:SolidPeso molecular:336.37CK-636
CAS:<p>CK-636 (CK-0944636), an Arp2/3 complex inhibitor, can inhibit actin polymerization induced by the human, fission yeast and bovine Arp2/3 complex.</p>Fórmula:C16H16N2OSPureza:98.1% - 98.88%Forma y color:SolidPeso molecular:284.38Phorbol 12-myristate 13-acetate
CAS:<p>Phorbol 12-myristate 13-acetate (PMA) belongs to the phorbol ester group of natural products and is an activator of PKC, SphK, and NF-κB.</p>Fórmula:C36H56O8Pureza:98.55% - >99.99%Forma y color:White To Off-White SolidPeso molecular:616.83N-Phenylbenzylamine
CAS:<p>A series of N-Phenylbenzylamine (Benzenemethanamine) as potential cytotoxic and antimitotic agents acting by inhibition of tubulin polymerization</p>Fórmula:C13H13NPureza:98.75%Forma y color:Colorless To Pale Yellow Crystalline PowderPeso molecular:183.25Tianeptine sodium salt
CAS:<p>Tianeptine sodium salt 是一种选择性5-HT 摄取促进剂，具有抗抑郁、抗焦虑和神经保护作用，可用于缓解疼痛的研究。</p>Fórmula:C21H24ClN2NaO4SPureza:99.82%Forma y color:SolidPeso molecular:458.93Daphnetin
CAS:<p>Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),</p>Fórmula:C9H6O4Pureza:97.47% - 99.8%Forma y color:SolidPeso molecular:178.14BTB-1
CAS:<p>BTB-1 (NSC156750) is a novel small molecule inhibitor of the mitotic motor protein Kif18A.</p>Fórmula:C12H8ClNO4SPureza:99.71%Forma y color:SolidPeso molecular:297.71Eptifibatide acetate (148031-34-9 free base)
CAS:<p>Eptifibatide acetate (148031-34-9), a cyclic heptapeptide GP IIb/IIIa inhibitor antiplatelet drug.</p>Fórmula:C35H49N11O9S2·xC2H4O2Pureza:99.7% - 99.87%Forma y color:SolidPeso molecular:831.96 (free base)KNK437
CAS:<p>KNK437 (Heat Shock Protein Inhibitor I), a pan-HSP inhibitor, suppresses the synthesis of inducible HSPs(HSP105, HSP72, and HSP40).</p>Fórmula:C13H11NO4Pureza:98.90%Forma y color:SolidPeso molecular:245.23TAS-301
CAS:<p>TAS-301, an inhibitor of smooth muscle cell migration and proliferation, inhibits intimal thickening after balloon injury to rat carotid arteries.</p>Fórmula:C23H19NO3Pureza:99.55%Forma y color:SolidPeso molecular:357.4GNF-7
CAS:<p>GNF-7 is Bcr-Abl WT and Bcr-Abl T315I inhibitor with IC50 of 133 nM and 61 nM, respectively.</p>Fórmula:C28H24F3N7O2Pureza:97.05% - 99.7%Forma y color:SolidPeso molecular:547.53BRD9876
CAS:<p>BRD9876 is a selective inhibitor of MM1S growth.</p>Fórmula:C16H14N2Pureza:97.81%Forma y color:SolidPeso molecular:234.3Verbascoside
CAS:<p>Verbascoside (Kusaginin) is a protein kinase C inhibitor with antimicrobial, anti-inflammatory activities.</p>Fórmula:C29H36O15Pureza:97.46% - 99.55%Forma y color:SolidPeso molecular:624.59Aurothiomalate sodium
CAS:<p>Sodium aurothiomalate (Miochrysin) inhibits PKC-ι, TrxR; used as an anti-rheumatic and has anti-tumor properties.</p>Fórmula:C4H3AuNa2O4SPureza:99.66%Forma y color:SoildPeso molecular:390.07FRAX486
CAS:FRAX486 is a potent p21-activated kinase (PAK) inhibitor with IC50 values of 14, 33, 39 and 575 nM for PAK1, PAK2, PAK3 and PAK4 respectively.Fórmula:C25H23Cl2FN6OPureza:98.81% - 99.52%Forma y color:SolidPeso molecular:513.39Arginine-glycine-aspartic acid
CAS:<p>RGD (RGD (Arg-Gly-Asp) Peptides) (Arg-Gly-Asp) Peptides is a cell adhesion motif which can mimic cell adhesion proteins and bind to integrins.</p>Fórmula:C12H22N6O6Pureza:99.11%Forma y color:SolidPeso molecular:346.34A-205804
CAS:<p>A-205804 is a specific and effective inhibitor of E-selectin( IC50=20 nM ) and ICAM-1(IC50=25 nM) expression.</p>Fórmula:C15H12N2OS2Pureza:98.07% - 98.52%Forma y color:SolidPeso molecular:300.4MAP4343
CAS:<p>Map4343, a 3-methyl ether pregnenolone derivative, binds MAP2, boosts tubulin polymerization, spurs neurite growth, and guards neurons.</p>Fórmula:C22H34O2Pureza:97.024%Forma y color:SolidPeso molecular:330.5HSF1A
CAS:<p>HSF1A is a cell-permeable activator of HSF1 that protects mammalian cells against stress-induced apoptosis.</p>Fórmula:C21H19N3O2S2Pureza:98.89%Forma y color:SolidPeso molecular:409.52PND-1186
CAS:<p>PND-1186 (VS-4718) is a reversible and specific FAK inhibitor (IC50: 1.5 nM).</p>Fórmula:C25H26F3N5O3Pureza:99.14% - 99.75%Forma y color:SolidPeso molecular:501.5Milnacipran ((1S-cis) hydrochloride)
CAS:<p>Milnacipran (1S-cis) hydrochloride (Levomilnacipran Hydrochloride) is a serotonin-norepinephrine reuptake inhibitor (SNRI), treatment of fibromyalgia.</p>Fórmula:C15H23ClN2OPureza:99.81%Forma y color:SolidPeso molecular:282.81TNIK-IN-2
CAS:<p>TNIK-IN-2 is an inhibitor Traf2- and Nck-interacting protein kinase (TNIK, IC50 = 1.33 μM)) which is a downstream signal protein of the Wnt/β-catenin pathway.</p>Fórmula:C22H19N3O3Pureza:99.54%Forma y color:SolidPeso molecular:373.4Curvulin
CAS:<p>Curvulin is the active metabolite isolated from Paraphoma sp. VIZR 1.46. Curvularin inhibits iNOS expression and microtubule assembly.</p>Fórmula:C12H14O5Pureza:98.65%Forma y color:SolidPeso molecular:238.24TASP0415914
CAS:<p>TASP0415914 is an orally potent inhibitor of phosphoinositide 3-kinase γ (PI3Kγ). T</p>Fórmula:C13H17N5O3SPureza:98.14%Forma y color:SolidPeso molecular:323.37Smurf1-IN-A01
CAS:<p>Smurf1-IN-A01 is a potent Smurf1 inhibitor enhancing BMP-2, with a Kd of 3.664 nM, preventing Smad1/5 degradation.</p>Fórmula:C22H20ClF3N4O3SPureza:99.46%Forma y color:SolidPeso molecular:512.93Mavacamten
CAS:<p>Mavacamten (MYK-461) is an orally bioavailable inhibitor of cardiac myosin ATPase,( IC50s of 490, 711 nM for bovine cardiac and human cardiac, respectively)</p>Fórmula:C15H19N3O2Pureza:99.53% - 99.98%Forma y color:SolidPeso molecular:273.33Hydroxy-Dynasore
CAS:<p>Hydroxy-Dynasore (Dyngo-4a) , a effective dynamin inhibitor, inhibits withDynI (brain), DynI (rec), and DynII (rec) of IC50 of 0.38 μM, 1.1 μM, and 2.3 μM,</p>Fórmula:C18H14N2O5Pureza:97.60% - >99.99%Forma y color:SolidPeso molecular:338.31TB500
CAS:<p>TB-500 is a synthesised peptide, essentially a short-chain version of the naturally occurring Thymosin Beta-4.</p>Fórmula:C38H68N10O14Pureza:99.51%Forma y color:SolidPeso molecular:889.01PKCβ inhibitor 1
CAS:<p>PKCβ inhibitor 1 (KUN79359)(KUN79359) is a potent, selective and ATP-competitive inhibitor of PKC isozymes(IC50s of 21 and 5 nM for human PKCβ1 and PKCβ2,</p>Fórmula:C24H21N5O2Pureza:99.33%Forma y color:SolidPeso molecular:411.46ARQ 621
CAS:<p>ARQ 621 is an allosteric, and selective Eg5 mitotic motor protein inhibitor. Phase 1.</p>Fórmula:C28H24Cl2FN5O2Pureza:97.01% - 98.38%Forma y color:SolidPeso molecular:552.43HA-100
CAS:<p>HA-100 is an inhibitor of protein kinase</p>Fórmula:C13H15N3O2SPureza:99.44%Forma y color:Pale Yellow Crystalline SolidPeso molecular:277.34Gap19
CAS:<p>Gap19 is a peptide that corresponds to a sequence on the cytoplasmic loop (CL) of Cx43.</p>Fórmula:C55H96N14O13Pureza:97.67%Forma y color:SolidPeso molecular:1161.44HM03
CAS:<p>HM03 is a potent and selective inhibitor of HSPA5, and has anticancer activity.</p>Fórmula:C26H27ClN4O2Pureza:97.15%Forma y color:SolidPeso molecular:462.97Taurolithocholic acid sodium salt
CAS:<p>Taurolithocholic acid sodium salt (Sodium taurolithocholate) is the major human metabolite, a bile acid which inhibits radioligand binding to muscarinic M1, but</p>Fórmula:C26H44NNaO5SPureza:99.79% - 99.93%Forma y color:SolidPeso molecular:505.69Multi-kinase inhibitor 1
CAS:<p>Multi-kinase inhibitor 1 (Multi-kinase inhibitor I) is a Multi-kinase inhibitor.</p>Fórmula:C20H17F3N4O3Pureza:99.34%Forma y color:SolidPeso molecular:418.37BAY1125976
CAS:<p>BAY1125976 is an allosteric inhibitor of Akt1 and Akt2 (IC50s of 5.2 and 18 nM, respectively, in a time-resolved FRET assay)</p>Fórmula:C23H21N5OPureza:99.28% - ≥98%Forma y color:SolidPeso molecular:383.45BIIB021
CAS:<p>BIIB021 (CNF2024) is an orally-available, fully synthetic inhibitor of HSP90(Ki=1.7 nM, EC50=38 nM).</p>Fórmula:C14H15ClN6OPureza:98% - 99.82%Forma y color:SolidPeso molecular:318.76Desmethylglycitein
CAS:<p>Desmethylglycitein (6,7,4'-Trihydroxyisoflavone) , is a novel inhibitor of PKCα in suppressing solar UV-induced matrix metalloproteinase 1, which has</p>Fórmula:C15H10O5Pureza:97.93%Forma y color:SolidPeso molecular:270.24Hexapeptide-10 Acetate
<p>Hexapeptide-10 Acetate (Hexapeptide-10 Acetate) is a synthetic peptide.</p>Fórmula:C30H57N7O10Pureza:98.84%Forma y color:SolidPeso molecular:675.81KW-2478
CAS:<p>KW-2478 is a non-ansamycin HSP90 inhibitor with IC50 of 3.8 nM.</p>Fórmula:C30H42N2O9Pureza:98.68% - 99.52%Forma y color:SolidPeso molecular:574.66PU-H54
CAS:<p>PU-H54 is a purine-derived Grp94 inhibitor targeting the S2 subpocket's unique binding region.</p>Fórmula:C18H19N5SPureza:99.13%Forma y color:SolidPeso molecular:337.44CZC-8004
CAS:<p>CZC-8004 (CZC-00008004) is a pan-kinase(ABL kinase) inhibitor and binds a range of tyrosine kinases.</p>Fórmula:C17H16FN5Pureza:99.29%Forma y color:SolidPeso molecular:309.34LXW7
CAS:<p>LXW7 is an octamer disulfide cyclic peptide and αvβ3 integrin ligand, acts as a potent and specific endothelial progenitor cells (EPCs) and endothelial cells (</p>Fórmula:C29H48N12O12S2Pureza:>99.99%Forma y color:SolidPeso molecular:820.89Decursinol angelate
CAS:<p>Decursinol angelate is anti-tumor, anti-inflammatory, anti-oxidant, hepatoprotective, and inhibits VEGF and cancer cell invasion.</p>Fórmula:C19H20O5Pureza:99.93%Forma y color:SolidPeso molecular:328.36MMAF
CAS:<p>MMAF (MonoMethyl auristatin F), an antimitotic agent, inhibits cell division by blocking the polymerization of tubulin.</p>Fórmula:C39H65N5O8Pureza:97.00% - 99.88%Forma y color:SolidPeso molecular:731.96Clanfenur
CAS:<p>Clanfenur belongs to a new group of substituted benzoylphenylureas. The drug shows both in vitro and in vivo antitumour activity.</p>Fórmula:C16H15ClFN3O2Pureza:99.93%Forma y color:SolidPeso molecular:335.76Ispinesib
CAS:<p>Ispinesib (SB-715992), a selective, effectvie and reversible inhibitor of kinesin spindle protein (KSP), is derived from quinazolinone, with antineoplastic</p>Fórmula:C30H33ClN4O2Pureza:98% - 99.09%Forma y color:SolidPeso molecular:517.06Gap 26
CAS:<p>Gap 26 is a mimetic peptide corresponding to the residues 63-75 of connexin 43, which is a gap junction blocker.</p>Fórmula:C70H107N19O19SPureza:98.26%Forma y color:SolidPeso molecular:1550.78Dasatinib N-oxide
CAS:<p>Dasatinib N-oxide is a key metabolite and potential impurity of the kinase inhibitor dasatinib.</p>Fórmula:C22H26ClN7O3SPureza:98.54% - 99.94%Forma y color:SolidPeso molecular:504PF04929113
CAS:<p>PF04929113 (SNX-5422), a synthetic small molecule Hsp90 inhibitor, offers potent efficacy orally for various cancers.</p>Fórmula:C25H30F3N5O4Pureza:99.04%Forma y color:SolidPeso molecular:521.53XL888
CAS:<p>XL888 is an orally bioavailable Hsp90 inhibitor, blocking cell proliferation and inducing tumor regression with an IC50 of 24 nM.</p>Fórmula:C29H37N5O3Pureza:99.18%Forma y color:SolidPeso molecular:503.64Sovilnesib
CAS:<p>Sovilnesib is a kinesin-like protein KIF18A inhibitor. Sovilnesib can be used for the cancer research.</p>Fórmula:C26H34F2N6O4SPureza:99.57%Forma y color:SolidPeso molecular:564.65H-Gly-Arg-Gly-Asp-Asn-Pro-OH
CAS:<p>RGD peptide (GRGDNP) (RGD peptide GRGDNP(2TFA)) is a integrin-ligand interactions inhibitor.</p>Fórmula:C23H38N10O10Pureza:>99.99%Forma y color:SolidPeso molecular:614.61PKC ζ pseudosubstrate acetate
<p>PKC ζ pseudosubstrate acetate is an inhibitor of protein kinase C (PKC) ζ; attached to cell permeabilisation Antennapedia domain vector peptide.</p>Fórmula:C78H132N30O18Pureza:98.78%Forma y color:SolidPeso molecular:1778.10ILK-IN-2
CAS:<p>ILK-IN-2 (OSU-T315) is a novel potent, orally active ILK (integrin-linked kinase) inhibitor with IC50 of 0.6 μM.</p>Fórmula:C30H30F3N5OPureza:99.30%Forma y color:SolidPeso molecular:533.59Fingolimod hydrochloride
CAS:<p>Fingolimod hydrochloride (FTY720) , a novel immune modulator, is a sphingosine 1-phosphate (S1P) antagonist (IC50: 0.033 nM in K562 and NK cells).</p>Fórmula:C19H34ClNO2Pureza:99.26% - 99.83%Forma y color:White SolidPeso molecular:343.93Spastazoline
CAS:<p>Spastazoline is a potent and selective inhibitor of spastin(Human spastin with IC50 of 99 nM ).</p>Fórmula:C20H30N8Pureza:99.23%Forma y color:SolidPeso molecular:382.51Capivasertib
CAS:<p>Capivasertib (AZD5363) is a broad-spectrum AKT inhibitor with inhibitory activity against Akt1, Akt2, and Akt3 (IC50=3/7/7 nM) with oral activity.</p>Fórmula:C21H25ClN6O2Pureza:97.59% - 99.6%Forma y color:SolidPeso molecular:428.92CWHM-12
CAS:<p>CWHM-12 is a potent inhibitor of αV integrins (IC50s of 0.2/0.8/1.5/1.8 nM for αvβ8/αvβ3/αvβ6/αvβ1).</p>Fórmula:C26H32BrN5O6Pureza:98.05% - 99.83%Forma y color:SolidPeso molecular:590.47Mitoxantrone
CAS:<p>Mitoxantrone: anthracenedione antibiotic, disrupts DNA/RNA replication, binds to topoisomerase II, less cardiotoxic than doxorubicin.</p>Fórmula:C22H28N4O6Pureza:96.29% - 98.74%Forma y color:Blue PowderPeso molecular:444.48Degrasyn
CAS:<p>Degrasyn (WP1130) inhibits DUBs (USP5, UCH-L1, USP9x, USP14, UCH37) and Bcr/Abl without affecting the 20S proteasome.</p>Fórmula:C19H18BrN3OPureza:98.32% - 99.98%Forma y color:SolidPeso molecular:384.27Mps1-IN-1 dihydrochloride
CAS:<p>Mps1-IN-1 dihydrochloride, a potent ATP-competitive inhibitor of Mps1 kinase, exhibits an IC50 of 367 nM.</p>Fórmula:C28H35Cl2N5O4SForma y color:SolidPeso molecular:608.58Cyclo(-RGDfK) TFA
CAS:<p>Cyclo(-RGDfK) is a selective αvβ3 integrin inhibitor(IC50 : 0.94 nM).</p>Fórmula:C29H42F3N9O9Pureza:98.99% - 99.54%Forma y color:SolidPeso molecular:717.69Fingolimod
CAS:<p>Fingolimod (FTY-720A) is an antagonist of sphingosine 1-phosphate (S1P) (IC50 of 0.033 nM in K562 and NK cells).</p>Fórmula:C19H33NO2Pureza:99.53% - 99.6%Forma y color:SolidPeso molecular:307.47AG957
CAS:<p>Tyrphostin AG957, a tyrosine kinase inhibitor with anti-BCR/ABL tyrosine kinase activity restores beta1 integrin-mediated adhesion and inhibitory signaling in</p>Fórmula:C15H15NO4Pureza:98.82%Forma y color:SolidPeso molecular:273.28[Ala113]-MBP (104-118) acetate
<p>[Ala113]MBP(104-118) acetate is an noncompetitive peptide inhibitors of protein kinase C (PKC), with IC50s ranging from 28-62 μM.</p>Fórmula:C69H108N20O21Pureza:97.72%Forma y color:SolidPeso molecular:1553.74CK-869
CAS:<p>CK-869 is an Actin-Related Protein 2/3 (ARP2/3) complex inhibitor(IC50 of 7 μM),and is useful tools for the investigation of the Arp2/3 complex.</p>Fórmula:C17H16BrNO3SPureza:99.85%Forma y color:SolidPeso molecular:394.28Aficamten
CAS:<p>Aficamten is a Next-Generation Cardiac Myosin Inhibitor for the Treatment of Hypertrophic Cardiomyopathy.</p>Fórmula:C18H19N5O2Pureza:99.19% - 99.57%Forma y color:SolidPeso molecular:337.38Imatinib
CAS:<p>Imatinib (STI571) is a multi-targeted receptor tyrosine kinase inhibitor that selectively inhibits the kinase activities of BCR/ABL, v-Abl, PDGFR, and c-kit</p>Fórmula:C29H31N7OPureza:99.42% - 99.94%Forma y color:Off White PowderPeso molecular:493.6PIR 3.5
CAS:<p>PIR 3.5 (6,6′-Dithiodi(2-naphthol)) is a negative control of IPA 3 which is a Pak1 inhibitor.</p>Fórmula:C20H14O2S2Pureza:98.08%Forma y color:SolidPeso molecular:350.45Staurosporine
CAS:<p>Staurosporine (AM-2282) is a protein kinase inhibitor with ATP-competitive and non-selective inhibitory activity (IC50=6/15/2/3/3000 nM) against PKC, PKA, c-Fgr</p>Fórmula:C28H26N4O3Pureza:99.24% - 99.82%Forma y color:Off-White PowderPeso molecular:466.53MMAD
CAS:<p>MMAD (Demethyldolastatin 10) is a potent tubulin inhibitor. MMAD is a toxin payload in antibody drug conjugates (ADCs).</p>Fórmula:C41H66N6O6SPureza:99.25% - 99.91%Forma y color:SolidPeso molecular:771.06Flumatinib
CAS:<p>Flumatinib (HHGV678) is an orally bioavailable tyrosine kinase inhibitor flumatinib, with potential antineoplastic activity.</p>Fórmula:C29H29F3N8OPureza:99.39% - 99.95%Forma y color:SolidPeso molecular:562.59XL228
CAS:<p>XL228 is an inhibitor of multi-targeted tyrosine kinase (IC50s: 5, 3.1, 1.6, 6.1, 2 nM for Bcr-Abl, Aurora A, IGF-1R, Src, and Lyn, respectively).</p>Fórmula:C22H31N9OPureza:99.07%Forma y color:SolidPeso molecular:437.54AT9283
CAS:<p>AT9283 (J-504568) is an effective multi-targeted inhibitor of JAK2(IC50=1.2 nM) and JAK3(IC50=1.1 nM), Aurora A, Aurora B and Abl(T315I).</p>Fórmula:C19H23N7O2Pureza:99.83% - 99.98%Forma y color:SolidPeso molecular:381.43TR-14035
CAS:<p>TR-14035 (MDK-1191) is a dual antagonist of α4β7/α4β1 integrins (IC50s: 7/87nM).</p>Fórmula:C24H21Cl2NO5Pureza:98.98%Forma y color:SolidPeso molecular:474.33OSU-T315
CAS:<p>OSU-T315 (OSU-T315 (1,5-regioisomer)) (1,5-regioisomer) is a ILK inhibitor.</p>Fórmula:C30H30F3N5OPureza:98.69%Forma y color:SolidPeso molecular:533.59Onalespib
CAS:<p>Onalespib (AT13387) is an oral Hsp90 inhibitor with anticancer potential, disrupting tumor cell growth and survival.</p>Fórmula:C24H31N3O3Pureza:98.05% - 99.66%Forma y color:SolidPeso molecular:409.52TPPB
CAS:<p>TPPB is a kinase C activator of cell-permeable benzolactam-derived protein (Ki: 11.9 nM).</p>Fórmula:C27H30F3N3O3Pureza:97.71% - 98.00%Forma y color:SolidPeso molecular:501.54Albendazole sulfoxide
CAS:Albendazole sulfoxide (Ricobendazole) is a metabolite of Albendazole, an anthelmintic.Fórmula:C12H15N3O3SPureza:97.29%Forma y color:White To Off-White PowderPeso molecular:281.33Tirbanibulin
CAS:<p>Tirbanibulin (KX2-391) is a highly selective Src kinase inhibitor that has demonstrated efficacy in pre-Clinicalal animal models of a variety of cancers.</p>Fórmula:C26H29N3O3Pureza:99.43% - 99.67%Forma y color:SolidPeso molecular:431.53Ro 31-8220 Mesylate
CAS:<p>Ro 31-8220 Mesylate (Bisindolylmaleimide IX mesylate) is a pan-PKC inhibitor, and also shows potent inhibition against MSK1, MAPKAP-K1b, S6K1, and GSK3β.</p>Fórmula:C25H23N5O2S·CH4O3SPureza:98.79% - 99.02%Forma y color:SolidPeso molecular:553.65Flumatinib mesylate
CAS:<p>Flumatinib mesylate (HHGV678 mesylate) is a selective inhibitor of c-Abl, PDGFRβ and c-Kit, effectively overcomes drug resistance of certain KIT mutants.</p>Fórmula:C30H33F3N8O4SPureza:99.82%Forma y color:SolidPeso molecular:658.69MitoBloCK-10
CAS:<p>MitoBloCK-10 inhibits Tim44-Hsp70 binding; first to reduce PAM complex activity.</p>Fórmula:C12H8FN3O3SPureza:99.51%Forma y color:SolidPeso molecular:293.27D-64131
CAS:<p>D-64131 is a tubulin polymerization inhibitor with an IC50 value of 0.53 μM.</p>Fórmula:C16H13NO2Pureza:99.48% - 99.67%Forma y color:SolidPeso molecular:251.28Procyanidin A1
CAS:<p>Procyanidin A1 (Proanthocyanidin A1) has antiallergic effects, it inhibits degranulation downstream of protein kinase C activation or Ca2+.</p>Fórmula:C30H24O12Pureza:99.52%Forma y color:SolidPeso molecular:576.5KBU2046
CAS:<p>KBU2046: oral anti-metastasis compound, enhances survival, targets chaperone complexes, not a typical HSP90 inhibitor.</p>Fórmula:C15H11FO2Pureza:99.89%Forma y color:SolidPeso molecular:242.24HSP27 inhibitor J2
CAS:<p>HSP27 inhibitor J2 (J2) (J2) is a HSP27 inhibitor, inhibits a production of HSP27 giant polymers, thereby having an effect of inhibiting a chaperone function of</p>Fórmula:C13H12O4SPureza:99.51%Forma y color:SolidPeso molecular:264.3Dynasore
CAS:<p>Dynasore, a cell-permeable dynamin inhibitor, blocks GTPase of dynamin 1/2 and Drp1 (IC50: 15 μM) without affecting other small GTPases.</p>Fórmula:C18H14N2O4Pureza:95.85% - 99.22%Forma y color:SolidPeso molecular:322.31Yoda 1
CAS:<p>Yoda 1 is an agonist of the Piezo1 channel that agonizes human- and mouse-derived Piezo1. Yoda 1 is also an inhibitor of GlyT2. Cost-effective, quality assurance.</p>Fórmula:C13H8Cl2N4S2Pureza:98% - 99.98%Forma y color:SolidPeso molecular:355.27Borussertib
CAS:<p>Borussertib is a covalent-allosteric and first-in-class inhibitor of protein kinase Akt(IC50 of 0.8 nM and a Ki of 2.2 nM for Aktwt)</p>Fórmula:C36H32N6O3Pureza:99.00%Forma y color:SolidPeso molecular:596.68NRX-252262
CAS:<p>NRX-252262 is a potent enhancer of the interaction between β-Catenin, and its cognate E3 ligase, SCFβ-TrCP, induces mutant β-catenin degradation(EC50：3.8 nM)</p>Fórmula:C23H17Cl2F3N2O4SPureza:98.94% - 99.87%Forma y color:SolidPeso molecular:545.36Ingenol
CAS:<p>Ingenol mebutate treats actinic keratosis, has anticancer properties, and may reactivate latent HIV.</p>Fórmula:C20H28O5Pureza:99.78% - 99.87%Forma y color:SolidPeso molecular:348.432-hydroxy Flutamide
CAS:<p>2-hydroxy Flutamide is competitive inhibition of androgen receptor (AR) for the treatment of prostate cancer</p>Fórmula:C11H11F3N2O4Pureza:99.45% - 99.82%Forma y color:SolidPeso molecular:292.21BX517
CAS:<p>BX517 (PDK1 inhibitor 2) is a potent and selective inhibitor of PDK1.</p>Fórmula:C15H14N4O2Pureza:99.26%Forma y color:SolidPeso molecular:282.3Sotrastaurin
CAS:<p>Sotrastaurin (AEB071) is a potent pan-PKC inhibitor (Kis: 0.95/0.64/2.1/3.2/1.8/0.22 nM for PKCα/βI/δ/ε/η/θ).</p>Fórmula:C25H22N6O2Pureza:98% - 99.70%Forma y color:SolidPeso molecular:438.48PF-431396
CAS:<p>PF-431396 is a dual PYK2/FAK inhibitor (IC50: 11/2 nM).</p>Fórmula:C22H21F3N6O3SPureza:98.83% - 99.82%Forma y color:SolidPeso molecular:506.5
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