Señalización citoesquelética
Los inhibidores de la señalización del citoesqueleto son compuestos que interrumpen las vías de señalización que regulan el citoesqueleto, crucial para la forma celular, la motilidad, la división y el transporte intracelular. Estos inhibidores se utilizan para estudiar la dinámica de las proteínas del citoesqueleto, como la actina y la tubulina, y su papel en procesos como la migración celular, la adhesión y la metástasis del cáncer. Los inhibidores de la señalización del citoesqueleto son valiosos en la investigación sobre biología celular, cáncer y neurobiología. En CymitQuimica, ofrecemos una amplia gama de inhibidores de la señalización del citoesqueleto de alta calidad para apoyar su investigación en estas áreas.
Se han encontrado 1382 productos de "Señalización citoesquelética"
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Gamitrinib TPP hexafluorophosphate
CAS:<p>Gamitrinib TPP hexafluorophosphate is a mitochondrial-targeted HSP90 inhibitor with anticancer activity that can be used to study cancer and viral infection.</p>Fórmula:C52H65F6N3O8P2Pureza:98.52% - 98.52%Forma y color:SolidPeso molecular:1036.03Tubulin polymerization-IN-50
<p>Tubulin Polymerization-IN-50 (compound 7n) serves as an inhibitor of tubulin polymerization, exhibiting an IC50 of 5.05 μM in SK-Mel-28 cells and inducing cell</p>Fórmula:C24H20FN3O3Forma y color:SolidPeso molecular:417.43Alvespimycin TFA
<p>Alvespimycin (17-DMAG) TFA is a potent inhibitor of Hsp90, binding with an EC50 of 62 ± 29 nM.</p>Fórmula:C34H49F3N4O10Forma y color:SolidPeso molecular:730.34008NMS-E973
CAS:<p>NMS-E973 is a potent and selective Hsp90 inhibitor with DC50 of <10 nM for Hsp90 binding, no activiy against a panel of 52 diverse protein kinases.</p>Fórmula:C22H22N4O7Pureza:99.84%Forma y color:SolidPeso molecular:454.43Chromeceptin
CAS:<p>Chromeceptin is an inhibitor of the IGF signaling pathway, decreases the numbers of tumorsphere, and inhibits the AKT/mTOR pathway.</p>Fórmula:C19H16F3N3OPureza:99.85%Forma y color:SoildPeso molecular:359.35AB-3PRGD2
CAS:<p>AB-3PRGD2 is a radiolabeled agent that targets integrin αvβ3. It enhances tumor uptake and prolongs retention time in tumors, significantly improving the inhibition of tumor growth. AB-3PRGD2 also remodels the tumor immune microenvironment by upregulating PD-L1 expression and increasing tumor-infiltrating CD8+ T cells.</p>Fórmula:C137H215IN30O45SForma y color:SolidPeso molecular:3161.32ML-B01
<p>ML-B01 is an orally active inhibitor targeting Akt and PKA, with IC50 values of 2 nM and 136 nM, respectively. It demonstrates good blood-brain barrier (BBB) permeability in mice.</p>Fórmula:C24H31Cl2N5OForma y color:SolidPeso molecular:476.44KGP591
<p>KGP591, a tubulin polymerization inhibitor with an IC50 of 0.57 µM, effectively induces G2/M arrest, inhibits cell migration, and disrupts microtubule structure</p>Fórmula:C24H21NO5Forma y color:SolidPeso molecular:403.43Jatrophone
CAS:<p>Jatrophone is a novel inhibitor of the macrocyclic diterpenoid tumor.</p>Fórmula:C20H24O3Forma y color:SolidPeso molecular:312.4SIAIS178
CAS:<p>SIAIS178 is a potent and selective degrader of BCR-ABL based on PROTAC technology (IC50 of 24 nM).</p>Fórmula:C50H62ClN11O6S2Pureza:98.07%Forma y color:SolidPeso molecular:1012.68β-catenin-IN-7
<p>β-Catenin-IN-7 (Compound 9) is an inhibitor of β-catenin that disrupts its interaction with Tcf-4, consequently impeding Wnt-dependent gene expression, and</p>Fórmula:C17H13BrN2O2SForma y color:SolidPeso molecular:389.27PTA001_A4
<p>PTA001_A4 (Anti-CDH17/Cadherin-17 Antibody) is a humanized antibody targeting CDH17/Cadherin-17 with anti-tumor activity and inhibits tumor cell growth.</p>Pureza:95.8% (SDS-PAGE); 99.3% (SEC-HPLC) - 95.8% (SDS-PAGE); 99.3% (SEC-HPLC)Forma y color:Odour LiquidAD57
CAS:<p>AD57 is a potent inhibitor of both c-Src and Abl with IC50 of 0.025 μM and 0.041 μM, respectively.</p>Fórmula:C22H20F3N7OPureza:99.05%Forma y color:SoildPeso molecular:455.44SNIPER(ABL)-039
CAS:<p>SNIPER(ABL)-039, conjugating Dasatinib (ABL inhibitor) to LCL161 derivative (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of</p>Fórmula:C54H68ClN11O9S2Pureza:98%Forma y color:SolidPeso molecular:1114.77Pep2m, myristoylated
CAS:<p>Myristoylated pep2m peptide; inhibits GluA2-NSF interaction, reducing AMPA receptor function and surface expression.</p>Fórmula:C63H118N18O14SPureza:98%Forma y color:SolidPeso molecular:1383.8RA-PR058
<p>RA-PR058 is an orally active Ramalin derivative capable of penetrating the blood-brain barrier, with multi-target regulatory functions. By reducing BACE1 expression, decreasing excessive tau protein phosphorylation, and mitigating anxiety-like behaviors, along with displaying favorable pharmacokinetic properties, RA-PR058 shows promise as a multi-target modulator for Alzheimer's disease.</p>Fórmula:C11H15ClF3N3OForma y color:SolidPeso molecular:297.7Fibronectin CS1 Peptide
CAS:<p>Fibronectin CS1 peptide inhibits tumor metastasis, lacking RGD domain; may aid cancer therapy.</p>Fórmula:C38H64N8O15Pureza:98%Forma y color:SolidPeso molecular:872.96DSPE-PEG3000-iRGD
<p>DSPE-PEG3000-iRGD is a PEG compound comprising DSPE and the αv-integrin targeting peptide (iRGD). The iRGD peptide binds to αv-integrin and undergoes proteolytic cleavage within tumors to produce CRGDK/R, interacting with neuropilin-1. This results in tumor targeting and penetration capabilities. DSPE-PEG3000-iRGD is applicable in drug delivery.</p>Forma y color:Odour SolidDPH
CAS:<p>DPH is a potent cell permeable activator of c-Abl. It shows potent enzymatic and cellular activity in stimulating c-Abl activation.</p>Fórmula:C18H13FN4O2Pureza:99.65%Forma y color:SolidPeso molecular:336.32Pironetin
CAS:<p>Pironetin, from Streptomyces, inhibits microtubule polymerization and tumor growth, and causes cell cycle arrest.</p>Fórmula:C19H32O4Pureza:98%Forma y color:SolidPeso molecular:324.45
