Compuestos deuterados

<p>Applications Isosilybin A+B mixture - d3 is the isotope labelled mixture of Isosilybin A and Isosilybin B. Isosilybin (I901000) is useful in the treatment of liver disease.<br>References Parthasarathy, M.R., et al.: Phytochemistry, 18, 506 (1979),<br></p>

<p>Applications Used as an insecticide.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 1-Bromonaphthalene-d7 (cas# 37621-57-1) is a compound useful in organic synthesis.<br></p>

<p>Applications Tralomethrin-d5, is the labeled analogue of Tralomethrin (T712400), which is a pyrethroid insecticide. It is effective against most members of class Arachnida as well as insects.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Laskowski, D.A., et al.: Review Env. Conatmin. Toxic., 174, 49 (2002); Tanaka, Y., et al.: Shokuhin Eiseigaku Zasshi, 41, 335 (200);<br></p>

<p>Applications The active labelled component of the antifertility agent nicarbazin, in chicken, duck, and goose plasma.<br>References Polin, D., et al.: Poultry Sci., 35, 1367 (1956), Primus, T.M., et al.: J. Agric. Food Chem., 49, 3589 (2001),<br></p>

<p>Applications Benzene-13C6 ,is isotopically labelled benzene, an organic compound that is a natural constituent of crude oil and one of the most basic petrochemicals.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Feng, Z.X.. et al.: J. Phys. Chem. Lett. 4, 285 (2013); Pilling. M., et al.: Chem. Eng. Prog., 108, 32 (2012);<br></p>

<p>Applications Adamantane-d16 is used in the fast catalytic hydroxylation of hydrocarbons with ruthenium porphyrins. Unlabeled adamantane derivatives have been used to treat influenza, as well as serve as NMDA receptor channel blockers for a wide range of pharmaceutical application.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Wang, C. et al.: Inorg. Chem. 45, 4769 (2012); Thomas. A. et al.: J. Neurosci., 25, 3312 (2005); Deyde, V. et al.: Exp. Rev. Mol. Diag., 9, 493 (2009);<br></p>

<p>Applications Pentachlorothioanisole-13C6, is the labeled analogue of Pentachlorothioanisole (P238170), which can be used in the preparation of arenethiols and arenethiolates as seen in agrochemicals or fungicides.<br>References Dulik, D. et al.: Xenobiotica, 22, 325 (1992); Rakitin, O. et al.: Sci. Synth., 31a, 949 (2007);<br></p>

<p>Applications Labelled Aldicarb Sulfoxide (A514665). Aldicarb Sulfoxide is an analog of Aldicarb (A514650) detected in agricultural products as pesticide residue.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ashby, J., et al.: Environ. Mutagen., 7, 919 (1985), Ashby, J., et al.: Mutat. Res., 257, 229 (1991), Kazius, J., et al.: J. Med. Chem., 48, 312 (2005), Benigni, R., et al.: Mutagenesis, 25, 335 (2010),<br></p>

<p>Applications Ethanolamine-d7 (CAS# 1219802-89-7) is a useful isotopically labeled research compound.<br></p>

<p>Applications Betaine-d3 Hydrochloride is a useful gastric acidifier.<br>References Wilcken, D.E., et al.: N. Engl. J. Med., 309, 448 (1983),<br></p>

<p>Applications 2-Chloronaphthalene-d7 (CAS# 93951-84-9) is a useful isotopically labeled research compound.<br></p>

<p>Applications Vardenafil oxopiperazine-D6 is a labelled analogue of Vardenafil oxopiperazine (V098030)<br></p>

<p>Applications Griseofulvin-d3 is the labeled analogue of Griseofulvin (G787500), an antifungal drug. It is used both in animal and in humans, to treat rigworm infections of the skin and nails. It is derived from the mold Penicillium griseofulvum.Environmental contaminants; Food contaminants<br>References Oxford, et al.: Biochem. J., 33, 240 (1939); Townley, E.R., et al.: Anal. Profiles Drug Subs., 8, 219 (1979)<br></p>

<p>Applications Labelled Fenvalerate (F279450). An insecticide, used to control insects from food crops, animal feed and cotton products.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sharma, R., et al.: Environ. Ecol., 27, 1481 (2009), Choudhary, S., et al.: J. Industrial Poll. Cont., 25, 145 (2009), Tang, J., et al.: Pest Man. Sci., 66, 121 (2010), Ai, G., et al.: J. Agric. Food Chem., 58, 694 (2010),<br></p>

<p>Stability Hygroscopic<br>Applications Labelled Phosphocholine Chloride, a specific promoter of heparin and serum β-lipoprotein interaction. Phosphocholine Chloride protected the membranes of platelets, erythrocytes, and lysosomes against the labilizing action of various known membrane labilizers.<br>References Mookerjea, S. et al.: Biochem. Res. Biophys. Res. Comm., 53, 580 (1973); Caputi, A.P. et al.: Boll. Chim. Farmac., 117, 553 (1978):<br></p>

<p>Applications 2-Ethyl 13C6-toluene is a labelled aromatic standard.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Propoxyphenyl-​thiohydroxyhomosilde​nafil-d4 is labelled Propoxyphenyl-thiohydroxyhomosildenafil (P831630), an analogue of Hydroxythiohomo Sildenafil (H963150).<br>References Balayssac, S., et. al.: J. Pharmaceut. Biomed., 63, 135 (2012)<br></p>

<p>Applications Labelled Norflurazon (N684500). Pesticide.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References El-Nahhal, Y., et al.: J. Agric. Food Chem., 46, 3305 (1998),<br></p>

<p>Applications Isoproturon-d6 is deuterized or labeled form of Isoproturon (I874500), which is a pre-and post emergence herbicide for control of annual grasses and broad-leaved weeds. Herbicide.<br>References Fournier, J.-C., et al.: Chemosphere, 4, 207 (1975), Gonzales, P., et al.: Weed Res., 23, 39 (1983)<br></p>

<p>Applications An adenosine receptor ligand and a major metabolite of caffeine.<br>References Proc. Natl. Acad. Sci. USA 78, 3260 (1981); Cell Mol. Neurobiol., 3, 69 (1983); Eur. J. Pharmacol., 179, 295 (1990)<br></p>

<p>Applications T-705RTP-13C5 Sodium Salt is a labeled salt derivative of T-705 (F103350) which has activity against the lethal H5N1 influenza A viruses.<br>References Yousuke, F., et al.: Antimicrob Agent Chemother., 49, 981 (2005); Kiso, M., et al.: Proc. Natl. Acad. Sci. U.S.A., 107, 882 (2010)<br></p>

<p>Applications 16alpha-Hydroxy-17beta-estradiol-2,4-d2 (CAS# 53866-32-3) is a useful isotopically labeled research compound.<br></p>

<p>Applications Isotope labelled 1,3-Propanediol, a common organic reagent used in the synthesis of polymers and used in industrial organic chemistry for the synthesis of lubricants, foods, medicines and cosmetics.<br>References Sun, Y. et al.: Bioproc. Renew. Res. Commod. Bioprod., 289 (2014);<br></p>

<p>Applications 5-Oxo-DL-proline-d5 is a labelled cyclized derivative of L-Glutamic Acid (G596960). The pyroglutamate core has potential application for synthesis of novel anti-bacterials.<br>References Mischo A. et al.: ChemBioChem., 13, 1421 (2012); Angelov P. et al.: Org. Biomol. Chem.: 10, 3472 (2012);<br></p>

<p>Applications Labelled Mecoprop (M203052). Herbicide.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gagne, F., et al.: Environ. Res., 103, 238 (2007), LaChapelle, A., et al.: Reprod. Toxicol., 23, 20 (2007),<br></p>

<p>Applications Dibutyltin Dichloride-d18 is a labeled analogue of Dibutyltin Dichloride (D429550) (CAS# 683-18-1), which is an organotin compound that is widely used as a stabilizer for polyvinylchloride plastics. Studies show that exposure to Dibutyltin Dichloride induced acute interstitial pancreatitis in rats. Dibutyltin Dichloride showed in vitro trypanocidal activity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Merkord, J. et al.: Hum. Exp. Toxicol., 17, 144 (1998); Shuaibu, M.N. et al.: Parasitol. Res., 91, 5 (2003); Whalen, M.M. et al.: Toxicol. Sci., 104, 312 (2008);<br></p>

<p>Applications Isotope labelled N-Nitrosodiphenylamine (N525775), which is the N-nitroso analogue of diphenylamine that was once used as a rubber additive but is no longer due to undesirable carcinogenic effects (1). N-Nitrosodiphenylamine may have potential carcinogenic activity and is currently classified as a probable carcinogen by EPA with genetic toxicity (2,3).Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br>References 1. Boyland, D. et al.: Eur. J. Cancer. 1968. May;4(2):233-2342. Iversen, O. et al.: Eur. J. Cancer. 1980 May;16(5):695-8.3. McGregor, D. et al.: Mutat. Res. Rev. Gen. Toxicol. 1994 Jun:317(3):195-211<br></p>

<p>Applications Isotope labelled Triglycidyl isocyanurate is a reagent used in the synthesis of N-Benzyl Metaxalone (B285000), which is a muscle relaxant used to relax muscles and relieve pain.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Toth, P.E., et al.: Clin. Ther., 26, 1355 (2004)<br></p>

<p>Stability Hygroscopic<br>Applications Dioxybenzone-d3 is an isotopic analog of Dioxybenzone (D486365), a compound used in sunscreen formulations to block out UVB and UVA harmful rays.<br>References Baumgartner, V. et al.: J. Planar. Chrom. Modern. TLC., 22, 19 (2009); Kunisue, T. et al.: Anal. Meth., 2, 707 (2010);<br></p>

<p>Applications N-(2-Hydroxyethyl)nitotinamide-d4 is labelled N-(2-Hydroxyethyl)nitotinamide (H942365), an intermediate used to prepare oxadiazole oxide derivatives as vasodilators. It is also a derivative of Nicorandil (N398500) which is an antiaginal.<br>References Boschi, D., et al.: Bioorg. Med. Chem., 8, 1727 (2000); Nagai, H., et al.: Chem. Pharm. Bull., 32, 1063 (1984); Ma, C., et al.: J. Pharm. Biomed. Anal., 47, 677 (2008)<br></p>

<p>Applications A labelled isomer of dichloropropanol; shows metabolite toxicity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Omura, M., et al.: Bull. Environ. Contam. Toxicol., 55, 1 (1995),<br></p>

<p>Applications Labelled Propylparaben. An antimicrobial agent used in cosmetic products.<br>References Gilliland, D., et al.: J. Appl. Bacteriol., 72, 258 (1992), Routledge, E., et al.: Toxicol. Appl. Pharmacol., 153, 12 (1998), Miller, C., et al.: J. Biol. Chem., 272, 32824 (1997), Nakagawa, Y., et al.: Biochem. Pharmacol., 55, 1907 (1998),<br></p>

<p>Applications Nordihydrocapsaicin-d3 is labelled Nordihydrocapsaicin (N672600) which is a capsaicinoid and analog and congener of capsaicin in chili peppers.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Iwai, K., et al.: Agri. Biol. Chem., 43, 2493 (1979); Kozukue, N., et al.: J. Agr. Food Chem., 53, 9172 (2005)<br></p>

<p>Applications Methyl 2-Hydroxybenzoate-3,4,5,6-d4 (CAS# 1219802-12-6) is a useful isotopically labeled research compound.<br></p>

<p>Stability Hygroscopic<br>Applications 5-​Methyl-2,​4(1H,​3H)​-​pyrimidinedione-​2-​13C-​1,​3-​15N2 is an intermediate in synthesizing 5-Methyl-2’-deoxy Cytidine-13C,15N2 (M295904). It is an isotopic analog of 5-Methyl-2’-deoxy Cytidine (M295900), a Cytidine (C998300) analog and also an isostere of Thymidine (T412000).<br>References Sabini, E., et al.: J. Med. Chem., 51, 4219 (2008), Sabini, E., et al.: J. Mol. Biol., 378, 607 (2008)<br></p>

<p>Stability Volatile<br>Applications Isopropyl-d7-amine may act as a potential protease inhibitor but also takes part in numerous organic chemical reactions such as amide synthesis.<br> E0<br>References Dam, J.H. et al.: Chem. A. Eur. J., 16, 6820 (2010); Latli, B. et al.: J Labelled. Compd. Radiopharm., 48, 447 (2005);<br></p>

<p>Applications Bis(butoxyethyl) Phosphate-d4 is an isotope labelled analog of Bis(butoxyethyl) Phosphate. Bis(butoxyethyl) Phosphate is used in biological studies as to study metabolism of phosphate flame retardants and plasticizers found in human liver fractions.<br>References Van den Eede, N., et al.: Toxicol. Lett., 223, 9 (2013)<br></p>

<p>Applications A labelled chloropropanol which shows toxic effects.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Andersen, H., et al.: Toxicology, 136, 67 (1999), Fry, J., et al.: Food Chem. Toxicol., 37, 351 (1999), Garle, M., et al.: Xenobiotica, 29, 533 (1999),<br></p>

<p>Applications 2-Butanol-d3 has been used to examine the loss of water form metastable 2-butanol/Mn+ cations using mass spectrometry.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Schroder, D., Schwarz, H.: Int. J. Mass Spec., 231, 139 (2004)<br></p>

<p>Applications Labeled D-Mannitol is widespread in plants and plant exudates; obtained from manna and seaweeds. D-Mannitol is used in the food industry as anticaking and free-flow agent, flavoring agent, lubricant and release agent, stabilizer and thickener and nutritive sweetener.<br>References Pigman, W., et al.: The Carbohydrates, 249 (1957), Makkee, M., et al.: Chem. Commun., 930 (1980),<br></p>

<p>Applications 1-Pyren-2,3,4,5,6,7,8,9,10-d9-amine is derived from Pyrene-d10 (P849002), which is labelled Pyrene. Occurs in coal tar. Also obtained by the destructive hydrogenation of hard coal.<br>References Winterstein, et al.: Z. Physiol. Chem., 230, 162 (1934)<br></p>

<p>Applications A labelled form of Pirimicarb (P508768) which is a pesticide which is useful in cannabis testing kits as a component of pesticide mixes (P698240).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Tsuchiyama, T.; et al.: Journal of Chromatography A, 1524, 233 (2017).<br></p>

<p>Applications Fenpropidin-d10 is the labeled analogue of Fenpropidin (F249470), a fungicide.<br>References Leroux, P. Walker, A.: Eur. J. Plant Path., 135, 683 (2013); Zhao, H., et. al.: Ecotox. Environ. Safe., 77, 52 (2012)<br></p>

<p>Applications AOZ-HN-d4 is the isotope labelled analog of AOZ-HN (A699000); a metabolite of 3-Amino-2-oxazolidinone (AOZ, A618570) and 1-Formylnaphthalen-2-ol (F700825) which is a novel fluorescence agent.<br>References Sheng, L., et al.: Food Addit. Contam., 30, 2114 (2013); Du, N., et al.: J. Chromatogr. A, 1327, 90 (2014)<br></p>

<p>Applications Indole-3-Acetic-d2 Acid (cas# 24420-86-8) is a useful research chemical.<br></p>

<p>Applications 2,3,4-Trihydroxybenzophenone-2’,3’,4’,5’,6’-d5 is the isotope labelled analog of 2,3,4-Trihydroxybenzophenone; a trihydroxy derivative of Benzophenone (B204980) which is a compound used in the manufacturing of antihistamines, hypnotics, and insecticides.<br>References Wallace, W., et al.: Environ. Toxicol. Chem., 19, 962 (2000); Hayashi, T., et al.: Toxicol. Lett., 167, 1 (2006); Bechard, K., et al.: Aquat. Toxicol., 90, 310 (2008)<br></p>

<p>Stability Hygroscopic<br>Applications The labelled version of Ethylamine Hydrochloride, a chemical used in various chemical organic syntheses and biological studies.<br>References Miller, M.M. et al.: Bioorg. Med. Chem. Lett., 22, 6503 (2012); Yasui, K. et al.: Prot. Sci., 19, 486 (2010);<br></p>

<p>Applications Isotope labelled Melamine (M208703), which forms synthetic resins with formaldehyde. It remains largely non-metabolized in male Wistar rats with 90% of the administered dose excreted in the urine (1,2) and thus acts as a non-protein nitrogen food additive found in milk (3). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.<br>References 1. Mast, R. et al.: Food Chem Toxicol. 1983 Dec;21(6):807-10.2. Smith, J. et al.: Toxicol Appl Pharmacol. 1994 Apr;125(2):296-308.3. Anirudhan, T. et al.: Food Chem. 2017 Jul 15;227:85-92.<br></p>

<p>Applications Octadecanoic-18,18,18-d3 Acid (CAS# 62163-39-7) is a useful isotopically labeled research compound.<br></p>

<p>Applications Naphthalene-d8, is the labeled analogue of Naphthalene, a polycyclic aromatic hydrocarbons as micropollutants.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Di Toro, D., et al.: Environ. Toxicol. Chem., 19, 1971 (2000), Vines, C., et al.: Aquat. Toxicol., 51, 225 (2000), Incardona, J., et al.: Toxicol. Appl. Pharmacol., 196, 191 (2004), Junghans, M., et al.: Aquat. Toxicol., 76, 93 (2006),<br></p>

<p>Applications Triacetin-d5 is the isotope labelled analog of Triacetin (T720850); a compound used as a food additive and flavoring. Triacetin can be used as an excipient in pharmaceutical products where it is used as a humectant, a plasticizer, and as a solvent. Triacetin can also be used as a fuel additive as an antiknock agent.<br>References Mouret, A., et al.: Green Chem., 16 (1), 269 (2014); Snejdrova, E., et al.: Inter. J. Pharma., 458, 282 (2013)<br></p>

<p>Applications Ethylbenzene-d10 (cas# 25837-05-2) is a useful research chemical.<br></p>

<p>Applications Isotope labelled β-Alanine is a naturally occurring beta amino acid. β-Alanine is formed in vivo by the degradation of dihydrouracil (D449990) and carnosine. β-Alanine is also the rate-limiting precursor of carnosine, as a result supplementation with β-alanine increases the concentration of carnosine in muscles.<br></p>

<p>Applications Phenoxy-d5-acetic Acid (cas# 154492-74-7) is a compound useful in organic synthesis.<br></p>

<p>Applications N-Nitrosodiethylamine-d10 is a labelled form of N-Nitrosodiethylamine (N525465) which is a widely occurring nitrosamine that is one of the most important environmental carcinogens primarily inducing tumors of liver.NDMA and NDEA were found as an impurity in generic versions of valsartan, losartan and irbesartan.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Oda, Y., et al.: Mutation Research, Genetic Toxicology and Environmental Mutagenesis, 584, 1 (2005); Yamazaki, H., et al.: Carcinogenesis, 13, 1789 (1992);Chem. and Eng. News, p.5, Feb. 25, 2019<br></p>

<p>Applications Methionine-methyl-d3 is the labeled Methionine-methyl, a useful building block.<br></p>

<p>Applications Octanoic Acid-13C4 is an isotopic analog of Octanoic Acid (O237880), which is found naturally in the milk of various mammals. Its esters can be used in perfumery and also in the manufacture of dyes. It is also an antimicrobial pesticide used as a food contact surface sanitizer. Caprylic acid is also used in the treatment of some bacterial infections.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lide, D. R., et al.: CRC Handbook chem. Phys., 70th Ed. (1990); Beare-Rogers, J., et al.: Pue Appl. Chem., 73 (4), 685 (2001);<br></p>

<p>Applications The primary aroma compound of red raspberries, used in perfume compositions, shampoos, cosmetics and as a food additive.<br>References Aggarwal, S., et al.: Mol. Pharmacol., 69, 195 (2006), Beekwilder, J., et al.: Biotechnol. J., 2, 1270 (2007), Akiyama, M., et al.: J. Food Sci., 72, C388 (2007),<br></p>

<p>Applications 4-Chlorophenylamine-13C6 (cas# 89059-39-2) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 4-Hydroxybenzophenone-d4 is an isotopic analog of 4-Hydroxybenzophenone (H829305), a metabolite of benzophenone (B204980).<br>References Stocklinski, A. et al. Life Sciences 26, 365(1980)<br></p>

<p>Applications Norfloxacin-d5 is deuterium labeled Norfloxacin (N681000), a synthetic fluoroquinolone and an antibacterial agent. Norfloxacin can be used to treat urinary tract infections.<br>References Koga, H., et al.: J. Med. Chem., 23, 1358 (1980), Hirai, K., et al.: Antimicrob. Agents Chemother., 19, 188 (1981), Holmes, B., et al.: Drugs, 30, 482 (1985),<br></p>

<p>Stability Very Hygroscopic<br>Applications Metolachlor ESA-d6 Sodium Salt is deuterium labelled salt form of Metolachlor ESA (M338860) which is a synthetic herbicide.<br>References Mai, H., et al.: Aquat. Toxicol. 147, 48 (2014); McCarty, G. W., et al.: Sci Total Environ 473-474, 473 (2014);<br></p>

<p>Applications Uracil-d4 is the labelled compound form of Uracil (U801000) which is a nitrogenous base on RNA nucleosides.<br>References Seth, P., et al.: J. Med. Chem., 53, 8309 (2010); Cui, H., et al.: Eur. J. Med. Chem., 45, 5140 (2010)<br></p>

<p>Stability Light Sensitive, Volatile<br>Applications A labelled antibacterial agent.<br>References Kind, T., et al.: Anal. Biochem., 363, 185 (2007), Spratlin, J., et al.: Clin. Cancer Res., 15, 431 (2009),<br></p>

<p>Applications Sodium Butyrate (13c4, 99%) (cas# 312623-84-0) is a useful research chemical.<br></p>

<p>Applications Catechol-d4 (cas# 103963-58-2) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Labelled Endosulfan Sulfate, a pesticide used in the control and protection of plant and vegetation.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Weston, D. et al.: Env. Sci. Tech., 38, 2752 (2004); Antonious, G. et al.: Env. Tox. Chem., 16, 644 (1997);<br></p>

<p>Applications Methyl Salicylate-13C6 is an intermediate for the synthesis of Olsalazine-13C12 Sodium Salt (O586002), which is labelled Olsalazine (O586000). Dimer of Mesalazine (M258100), an anti-inflammatory drug used in the treatment of inflammatory bowel disease and ulcerative colitis.<br>References Willoughby, C.P., Gut, 23. 1081 (1982), Scand, J., et al.: Gastroenterol, 20, 607 (1985), Wadworth, A.N., et al.: Drugs, 41, 647 (1991)<br></p>

<p>Applications Isotope labelled penconazole is an conazole based fungicide that works by inhibiting cell membrane ergosterol biosynthesis, thus stopping the development of fungi.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sharma, H., et al.: J. Mycol. Plant. Pathol., 42, 494 (2012); Sen, K., et al.: Food. Chem. Toxicol., 50, 3990 (2012); Pitt, W.M., et al.: Plant Disease., 96, 1303 (2012);<br></p>

<p>Applications 4-Cumylphenol-d2 is a deuterated isotope of 4-Cumylphenol (C834580) which is a useful building block for polymers.<br></p>

<p>Applications Labelled Dodecyl Phthalate (D525380). Dodecyl Phthalate is used in the preparation of Cytarabine (C998100) derivatives as anticancer agents.<br>References Aoshima, M., et al.: Cancer Res., 36, 2726 (1976), Wang, N., et al.: Bioorg. Med. Chem. Lett., 15, 4064 (2005), Marie-Helene, G., et al.: Bioorg. Med. Chem., 2009, 17, 6340 (2009),<br></p>

<p>Applications 1-Bromobutane-2,2-d2 (CAS# 55724-40-8) is a useful isotopically labeled research compound.<br></p>

<p>Applications n-Nonane-d20 (CAS# 121578-11-8) is a useful isotopically labeled research compound.<br></p>

<p>Applications 4-Aminobutyric-2,2-d2 Acid (CAS# 67910-98-9) is a useful isotopically labeled research compound.<br></p>

<p>Applications Labeled Sucrose (S697000). Yuanzhen sugar is a polysaccharide polymer, containing a certain amount of fructooligosaccharides.<br>References Watanabe, T., et al.: Biosci. Biotech. Biochem., 72, 3167 (2008), You, Y., et al.: J. Agric. Food Chem., 57, 709 (2009),<br></p>

<p>Applications A labelled metabolite of a mixed disulfide S-(N,N-diethyldithiocarbamoyl)-N-acetyl-L-cysteine (AC-DDTC), an antimutagenic mixed disulfide from disulfiram.<br>References Madan, A., et al.: Drug Metab. Dispos., 23, 1153 (1995), Lambert, D., et al.: J. Med. Chem., 48, 5059 (2005), Tsuboi, K., et al.: J. Biol. Chem., 280, 11082 (2005),<br></p>

<p>Applications A labelled form of Spiromesifen (S683505), which is a useful insecticide and miticide in plant breeding. Also useful in cannabis testing kits as a component of pesticide mixes (P698240).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications N-Methyl-2,4-dinitroaniline-d3 (cas# 91808-45-6) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications The compund has cytotoxic effects. Labelled Norharmane.<br>References Elfarra, A., et al.: Drug Metab. Dispos., 26, 779 (1998), Da Costa, A., et al.: Biocell, 23, 65 (1999), Janetzky, B., et al.: Drug Dev. Res., 46, 51 (1999), Kutty, R., et al.: Toxicol. Appl. Pharmacol., 107, 377 (1991), Riederer, F., et al.: J. Neurochem., 81, 814 (2002), Schott, Y., et al.: Bioorg. Med. Chem. Lett., 16, 5840 (2006),<br></p>

<p>Applications Labelled Aldicarb Sulfone (A514660). Aldicarb Sulfone is an analog of Aldicarb (A514650) detected in agricultural products as pesticide residue.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ashby, J., et al.: Environ. Mutagen., 7, 919 (1985), Ashby, J., et al.: Mutat. Res., 257, 229 (1991), Kazius, J., et al.: J. Med. Chem., 48, 312 (2005), Benigni, R., et al.: Mutagenesis, 25, 335 (2010),<br></p>

<p>Stability Very Hygroscopic<br>Applications 4-Chlorobenzenesulfonic Acid-d4 Sodium Salt is a compound useful in organic synthesis.<br></p>

<p>Applications Acrylamide-13C3 is carbon-13 labeled Acrylamide (A191300). Acrylamide is a chemical intermediate in production of polyacrylamides that are use in protein electrophoresis (PAGE), synthesis of dyes and copolymers for contact lenses. It is reasonably anticipated to be a human carcinogen (1,2).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References (1) Mottram, D.S., et al.: Nature, 419, 448 (2002)(2) Tareke, E., et al.: J. Agric. Food Chem., 50, 4998 (2002)<br></p>

<p>Applications 2,6-Dichlorobenzamide-3,4,5-d3 (CAS# 1219804-28-0) is a useful isotopically labeled research compound.<br></p>

<p>Applications Labelled analogue of Sulfachlorpyridazine, an antibacterial compound.<br>References Wammer, K.: Environ. Toxicol. Chem. 25, 1480 (2006);<br></p>

<p>Applications Geraniol-D6 is the deuterium labeled analog of Geraniol, which is used in the synthesis of insect repellant. It is also used in the synthesis of Angelicoin A and Herecinone J, which inhibit collagen-induced platelet aggregation.<br>References Barnard, D. et al.: J. Med. Entomol., 41, 726 (2004); Mori K. et al.: Phytomedicine, 17, 1082 (2010);<br></p>

<p>Applications Carbon 13 Labelled analogue of Adenosine (A280400), a purine nucleoside that plays an important role in various biochemical processes.<br>References Long, X., et al.: J. Pharmacol. Exper. Ther., 335, 781 (2010); Ham, M., et al.: J. Pharmacol. Exper. Ther., 335, 607 (2010)<br></p>

<p>Applications Isotope labelled Sodium β-Hydroxyethoxyacetate is used in the synthesis of polymer microspheres that are magnetized and are used for enzyme catalysis or bioaffinity separations.<br>References Horak, D. et al.: Macromol. Biosci., 12, 647 (2012); Pestov, A. et al.: Russ. J. Coord. Chem., 38, 738 (2012);<br></p>

<p>Applications Labelled analogue of Hydrocinnamic Acid, a cinnamic acid derivative used in the compositions for the treatment of blood disorders using α-methylhydrocinnamic acid.<br>References Migliaccio, A., et al.: Blood, 76, 1150 (1990); McDonagh, K., et al.: J. Biol. Chem., 266, 11965 (1991);<br></p>

<p>Applications Labelled Ethylparaben. An antimicrobial agent used in cosmetic products.<br>References Gilliland, D., et al.: J. Appl. Bacteriol., 72, 258 (1992), Routledge, E., et al.: Toxicol. Appl. Pharmacol., 153, 12 (1998), Miller, C., et al.: J. Biol. Chem., 272, 32824 (1997), Nakagawa, Y., et al.: Biochem. Pharmacol., 55, 1907 (1998),<br></p>

<p>Applications Labelled Chrysene (C428000). Chrysene occurs in coal tar. Is formed during distillation of coal, in very small amount during distillation or pyrolysis of many fats and oils. Chrysene is one of the basic polycyclic aromatic hydrocarbon (PAH) which is toxic environmental pollutant and consistently exposed to sunlight. However, little information is available on its photogenotoxicity.  The objective of the present study was to analyze the effects of Chrysene, under environmental intensity of UVB (0.6 mW/cm2) in human skin epidermal cell line (HaCaT).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Anderson, D., et al.: Mutat. Res., 307, 261 (1994), Diamond, S., et al.: Environ. Toxicol. Chem., 25, 3015 (2006), Fotakis, G., et al.: Toxicol. Lett., 160, 171 (2006),<br></p>

<p>Applications Labelled 4-Nitrophenol (N496945). Used in the manufacturing of pharmaceuticals, fungicides, dyes.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>