Compuestos deuterados

Applications Palmitoyl-16,16,16-d3-L-carnitine Hydrochloride is the isotope labelled analog of Palmitoyl-L-carnitine Hydrochloride (P155050); a long-chain fatty ester of carnitine which is accumulated and released into the circulation in fatty-acid oxidation defects.
References Ventura, F., et al.: Clinica Chimica Acta, 281, 1 (1999); Pourfarzam, M., et al.: Clinical Chem,, 40, 2267 (1994); Schaefer, J., et al.: Pediatric Res., 37, 354 (1995)

Stability Volatile
Applications N-Hexane (D14, 98%) (cas# 21666-38-6) is a useful research chemical.

Applications (±)-3-Amino-iso-butyric-2,3,3-d3 Acid is the labeled version of DL-3-Aminoisobutyric Acid (A603043(P)), which is a useful compound for suppressing atherosclerosis in apolipoprotein E-knockout mouse.
References Shimba, Y., et al.: Bio. Pharma. Bull., 43, 1016 (2020)

Applications trans-2,cis-6-Nonadienal-D5 is a labelled analogue of trans-2,cis-6-Nonadienal (N649365). trans-2,cis-6-Nonadienal is an unsaturated aldehyde that is responsible for the cucumber smell of Synura petersenii, a freshwater colonial flagellate. trans-2,cis-6-Nonadienal is also a common natural and drinking water contaminant.
References Berra, T., et al.: Trans. Am. Fish. Soc., 111, 78 (1982); Kynclova, A., et al.: Nova Hedw. Bei., 136, 283 (2010); Ömür-Özbek, P. & Dietrich, A.: Environ. Sci. Tech., 39, 3957 (2005)

Applications 1-Naphthoic Acid-d7 (cas# 634179-80-9) is a compound useful in organic synthesis.

Applications Biochemical tool for selective reduction of disulfide bridges at low pH; reductant for redox assay.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Neuburger, M., et al.: Eur. J. Biochem., 267, 2882 (2000), Krijt, J., et al.: Clin. Chem., 47, 1821 (2001), Yen, T.-Y., et al.: J. Mass Spectrom., 37, 15 (2002),

Applications Dihexylphthalate-d4 is an labeled analog of Dihexylphthalate (B185430), which is a phthalic ester, which is used as a plasticizers for vinyl plastics. Phthalates may be associated with reproductive toxicity in humans and animals.
References Saido, K., et al.: ?J. Am. Oil Chem. Soc 61, 945 (1984); Foghmoes, S., et al.: J. Eur. Ceram. Soc. 36, 3441 (2016); Przybyli?ska, P. A. and Wyszkowski, M.: Ecol. Chem. Eng., S 23,347 (2016)

Applications Isotope labelled Melamine (M208703), which forms synthetic resins with formaldehyde. It remains largely non-metabolized in male Wistar rats with 90% of the administered dose excreted in the urine (1,2) and thus acts as a non-protein nitrogen food additive found in milk (3). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.
References 1. Mast, R. et al.: Food Chem Toxicol. 1983 Dec;21(6):807-10.2. Smith, J. et al.: Toxicol Appl Pharmacol. 1994 Apr;125(2):296-308.3. Anirudhan, T. et al.: Food Chem. 2017 Jul 15;227:85-92.

Applications n-Octadecane-d38 (CAS# 16416-31-2) is a useful isotopically labeled research compound.

Applications A deuterated acyclic nucleotide.

Applications A labelled form of Pirimicarb (P508768) which is a pesticide which is useful in cannabis testing kits as a component of pesticide mixes (P698240).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Tsuchiyama, T.; et al.: Journal of Chromatography A, 1524, 233 (2017).

Applications sotope labelled m-Cresol (C781915) is one of the components that make up liquid rice hull smoke, and may contribute to its anti-inflammatory effects in mice.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications Naphthalene-d8, is the labeled analogue of Naphthalene, a polycyclic aromatic hydrocarbons as micropollutants.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Di Toro, D., et al.: Environ. Toxicol. Chem., 19, 1971 (2000), Vines, C., et al.: Aquat. Toxicol., 51, 225 (2000), Incardona, J., et al.: Toxicol. Appl. Pharmacol., 196, 191 (2004), Junghans, M., et al.: Aquat. Toxicol., 76, 93 (2006),

Applications N-Nitrosodiethylamine-d10 is a labelled form of N-Nitrosodiethylamine (N525465) which is a widely occurring nitrosamine that is one of the most important environmental carcinogens primarily inducing tumors of liver.NDMA and NDEA were found as an impurity in generic versions of valsartan, losartan and irbesartan.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Oda, Y., et al.: Mutation Research, Genetic Toxicology and Environmental Mutagenesis, 584, 1 (2005); Yamazaki, H., et al.: Carcinogenesis, 13, 1789 (1992);Chem. and Eng. News, p.5, Feb. 25, 2019

Applications 1,3-Propylene-d6 Thiourea (CAS# 1219802-05-7) is a useful isotopically labeled research compound.

Applications 3-Fluoro-6-nitroanisole-d3 is a compound useful in organic synthesis.

Stability Hygroscopic
Applications Labelled Cholesterol (C432501). Cholesterol is the principal sterol of the higher animals. Cholesterol was found in all body tissues, especial in the brain, spinal cord, and in animal fats or oils. Cholesterol is the main constituent of gallstones.
References Rosin, Z., et al.: Physiol. Chem., 124, 282 (1923), Schoenheimer, et al.: J. Biol. Chem., 105, 355 (1934), Gemant, et al.: Life Sci., 1, 233 (1962), Johnson, K., et al.: 4, 457 (1964),

Applications PyroPyronaridine-13C2 , d4 Tetraphosphate Salt is the labeled analogue of Pyronaridine (P997640), an antimalarial drug.
References Lee, D.W., et. al.: B. Kor. Chem. Soc., 35, 521 (2014)

Applications 3-Nitrobiphenyl is a nitrated benzene metabolite found in the bone marrow of B6C3F1 mice treated with benzene. 3-Nitrobiphenyl displays toxic effect on Tetrahymena pyriformis, Porphyromonas gingivalis, Selenomonas artemidis, and Streptococcus sobrinus.
References Laszlo, T. & Beteringhe, A.: QSAR Combinatorial Sci., 25, 944 (2006); Mintz, C. et al.: QSAR. Combinatorial Sci., 25, 912 (2006); Chen, K. et al.: Chem. Res. Toxicol., 17, 370 (2004)

Applications Acetamiprid-d3 is labelled Acetamiprid (A150800), a novel neonicotinid insecticide against Holotrichia consanguinea in sugarcane. Reports show that when exposed to neonicotinid pesticides honeybees have probelms returnign home after foraging and bumblebee colonies grow poorly and produce fewer queens. Also used in Cannabis testing.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Srivastava, A., et al.: Indian Sugar, 32, 673 (1983), Fleming, R., et al.: J. Econ. Entomol., 78, 1179 (1985), Rao, Ch.V., et al.: Pestology, 35, 47 (2011), Chem. and Eng. News 90: 10 (2012)