Compuestos deuterados

Applications An important isooptically labelled metabolite of benzene.
References Muller, G., et al. : Anal. Hazard. Sust. Biol. Mater., 5, 143 (1997)

Applications Isosilybin A+B mixture - d3 is the isotope labelled mixture of Isosilybin A and Isosilybin B. Isosilybin (I901000) is useful in the treatment of liver disease.
References Parthasarathy, M.R., et al.: Phytochemistry, 18, 506 (1979),

Stability Moisture Sensitive
Applications Labelled Bromoacetic Acid. Bromoacetic Acid is a relatively strong alkylating agent as well as a versatile building block used very commonly in organic synthesis. Bromoacetic acid has been shown to reversibly inhibit human erythrocyte carbonic anhydrase B.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Song, C. et al.: J. Org. Synth., 74, 8980 (2009); Kramer, S.P. et al.: J. Nat. Cancer Inst., 31, 297 (1963); Whitney, P.L. et al.: Eur. J. Biochem., 16, 126 (1970);

Applications Labelled Propafenone (P757500) impurity.
References Kitagawa, S., et al.: Biol. Pharm. Bull., 29, 1 (2006), Boccard, J., et al.: Eur. J. Pharm. Sci., 36, 254 (2009)

Applications Has a mutagenic potency
References Cash, G., et al.: Mutat. Res., 491, 31 (2001), Cash, G., et al.: Environ. Toxicol. Chem., 21, 2095 (2002), Glende, C., et al.: Mutat. Res., 515, 15 (2002),

Stability Hygroscopic
Applications Labelled rac 3-Hydroxybutyric Acid (H833020). Optically active 3-hydroxybutyric acids are key intermediates of the biosynthesis and metabolism of fatty acids and exist widely in biological systems.
References Freeman, J., et al.: Pediatrics, 102, 1358 (1998), Thio, L., et al.: Neurology, 54, 325 (2000), Rho, J., et al.: Epilepsia, 43, 358 (2002),

Applications Acrylamide-13C3 is carbon-13 labeled Acrylamide (A191300). Acrylamide is a chemical intermediate in production of polyacrylamides that are use in protein electrophoresis (PAGE), synthesis of dyes and copolymers for contact lenses. It is reasonably anticipated to be a human carcinogen (1,2).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References (1) Mottram, D.S., et al.: Nature, 419, 448 (2002)(2) Tareke, E., et al.: J. Agric. Food Chem., 50, 4998 (2002)

Applications A labelled metabolite of ethanol in humans and a potential biomarker of acute alcohol intake.
References Jones, A., et al.: Forensic Sci. Int., 45, 217 (1990), Schmitt, G., et al.: J. Anal. Toxicol., 19, 91 (1995), Dahl, H., et al.: J. Anal. Toxicol., 26, 201 (2002), Stephanson, N., et al.: Ther. Drug Monit., 24, 645 (2002), Helander, A., et al.: Clin. Chem., 50, 936 (2004),

Applications A labelled analog of a metabolite of Cetirizine and Hydroxyzine.

Applications (±)-3-Amino-iso-butyric-2,3,3-d3 Acid is the labeled version of DL-3-Aminoisobutyric Acid (A603043(P)), which is a useful compound for suppressing atherosclerosis in apolipoprotein E-knockout mouse.
References Shimba, Y., et al.: Bio. Pharma. Bull., 43, 1016 (2020)

Applications Isotope labelled Sodium β-Hydroxyethoxyacetate is used in the synthesis of polymer microspheres that are magnetized and are used for enzyme catalysis or bioaffinity separations.
References Horak, D. et al.: Macromol. Biosci., 12, 647 (2012); Pestov, A. et al.: Russ. J. Coord. Chem., 38, 738 (2012);

Applications Tris(2-butyloxyethyl)phosphate-d27 is the isotope analog of Tris(2-butyloxyethyl)phosphate. Tris(2-butyloxyethyl)phosphate,is an organophosphate, that can be used in the preparation of flame retardant, such as viscose fiber.
References Wang, Y., et al.: Fangzhi Xuebao, 33, 16 (2012); Xiaoshan, L. et al.: Aquatic Toxicology, 114, 173 (2012);

Applications 25-Hydroxyvitamin D2 (6,19,19-D3,97%) 100 Ug/Ml In Ethanol (cas# 1217467-39-4) is a useful research chemical.

Stability Volatile
Applications 2-Pentylfuran-d11 is the labeled analogue of 2-Pentylfuran (P284953), a volatile compound that is detected in meat smoke aerosol, rice aroma and tomato paste volatiles.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Rogge, W., et al.: Environ. Sci. Technol., 25, 1112 (1991); Buttery, R., et al.: J. Agric. Food Chem., 36, 1006 (1988); Buttery, R., et al.: J. Agric. Food Chem., 38, 336 (1990);

Applications Isotope labelled Nitrobenzene (N493000), used mainly in the production of the chemical precursor aniline as well as in azobenzene synthesis (1). Also may be reduced through magnetic iron oxide nanocrystals (2). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References 1. Yadav, G. et al.: Chem. Eng. J. 2013 Aug:221(1) pp500-5112. Cantillo, D. et al.: J. Org. Chem. 2013 May 3;78(9):4530-42.

Applications A labelled metabolite of a mixed disulfide S-(N,N-diethyldithiocarbamoyl)-N-acetyl-L-cysteine (AC-DDTC), an antimutagenic mixed disulfide from disulfiram.
References Madan, A., et al.: Drug Metab. Dispos., 23, 1153 (1995), Lambert, D., et al.: J. Med. Chem., 48, 5059 (2005), Tsuboi, K., et al.: J. Biol. Chem., 280, 11082 (2005),

Applications Cinnamic Acid-13C3 is the labelled analogue of Cinnamic Acid which is rac-form of trans-Cinnamic Acid (P336185) that is used in the synthesis of amides and esters through coupling reactions involving carboxylic acids and amines and N-methylation of amides and O-methylation of carboxylic acids.
References Kunishima, M. et al.: Tetrahedron, 55, 13159 (1999); Xia, Q. et al.: Org. Lett., 15, 3326 (2013);

Applications 1-Butan-1,1-d2-ol is the deuterium labeled version of 1-Butanol (B690045). It can be used in the synthesis of more complex isotope labeled compounds.
References Sharma, Shikha, et al.: J. of Radioanaly. and Nuc. Chem., 302(1), 583-591 (2014);Hirsekorn, Kurt F., et al.: J. of the Ame. Chem. Soc., 127(13), 4809-4830 (2005)

Applications Thiodiglycolic Acid-d4 acts as a reagent for the synthesis of metabolites of S-carboxymethyl-L-cysteine and S-methyl-L-Cysteine and of some isotoically labelled (2H, 13C) analogs.
References Meese, C. O., et al.: Archiv der Pharmazie, 323, 957 (1990)

Stability Hygroscopic
Applications Ethanolamine-13C2 Hydrochloride is the labeled analogue of Ethanolamine (E676500), which is used in the preparation of various pharmaceutical compounds and inhibitors. Ethanolamine-13C2, is also a 13C-labeled lipid precursor, used for the detection of phospholipid metabolism and the synthesis of phosphatidylethanolamine in T47D human breast cancer cells.
References Ronen, S. M., et al.: Magnetic Resonance Med., 25, 384 (1992); Lombardo, L. et al.: J. Med. Chem., 47, 6658 (2004); Egan, T.: J. Med. Chem., 43, 283 (2000);