Toxicología

<p>Applications Labelled analog of a triazinetrione anticoccidial. Coccidiostat.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Eberts, T., et al.: Clin. Chem., 25, 1440 (1979), Goodwin, M., et al.: Avian Dis., 29, 630 (1985), Sorensen, S., et al.: Clin. Chim. Acta, 264, 103 (1997), Conway, D., et al.: Poult. Sci., 280, 426 (2001),<br></p>

<p>Applications Amphetamine (A634240) analogue, a known hallucinogen,<br>References Tseng, L. et al. et al.: J. Pharmacol. Exp. Ther. 187, 263 (1976)<br></p>

<p>Applications 3-Chlorobenzotrichloride may be used as mosquito larvicide.<br>References Deonier, C.C., et. al.: Soap and Sanitary Chemicals, 22, 118 (1946)<br></p>

<p>Applications Antihistaminic, antiemetic, CNS depressant.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Edge, W., et al.: J. Pharm. Pharmacol., 5, 279 (1953), Huang, et al.: J. Pharm. Sci., 59, 772 (1970), Shearer, C.M., et al.: Anal. Profiles Drug Subs., 5, 429 (1976)<br></p>

<p>Applications 2-Cyano-2-(methoxyimino)acetic Acid is a cyano-oxime derivative used as a fungicide.<br>References Tellier, F., et al.: Pestic Biochem Physiol., 78, 151-160 (2004)<br></p>

<p>Stability Hygroscopic<br>Applications Lisdexamfetamine, a new, novel amphetamine product, has been shown to provide efficacy upwards of 12 h in children and adults with a side effect profile similar to those of other longer-acting amphetamine products.Controlled substance.<br>References Biederman, J., et al.: Clin. Ther., 29, 450 (2007), Medori, R., et al.: Biol. Psychiatry., 63, 981 (2008), Krishnan, S., et al.: Clin. Drug Investig., 28, 745 (2008), Ramos-Quiroga, J., et al.: CNS Drugs, 22, 603 (2008),<br></p>

<p>Applications 4-Fluoro-3-phenoxybenzoic Acid is part of the group of pyrethroid pesticides. Pyrethroid pesticides are commonly used in tropical regions such as the Caribbean as household insecticides, pet sprays, and where malaria is endemic, impregnated into mosquito-repellent nets.<br>References Dewailly, E., et al.: Environ. Int., 63, 201 (2013),<br></p>

<p>Applications A labelled Phenothiazine (P318040) analog. Antipsychotic.<br>References Sartorelli, A.C., et al.: Experientia, 21, 457 ( 1965),<br></p>

<p>Stability Hygroscopic<br>Applications (R)-Haloxyfop Methyl Ester is a herbicide. It is used in the study of reduced rates of the acetyl-co enzyme A carboxylase (ACCase)-inhibiting herbicides.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Neve, P., et al.: Theoretical and Applied Genetics, 110, 1154 (2005); Delye, C., et al.: Pest Management Sci., 58, 474 (2002)<br></p>

<p>Applications A labelled nootropic. An inhibitor of acetylcholinesterase.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ohnishi, A., et al.: J. Clin. Pharmacol., 33, 1086 (1993), Galli, A., et al.: Eur. J. Pharmacol., 270, 189 (1994)<br></p>

<p>Applications Sodium Salt of Ampicillin, an orally active, semi-synthetic antibiotic; structurally related to penicillin. Antibacterial.<br>References Ivashkiv, E., et al.: Anal. Profiles Drug Subs., 2, 1 (1973), Campoli-Richards, D.M., et al.: Drugs, 33, 577 (1987), Sill, M. L., et al.: Antimicrob. Agents Chemother., 52, 1551 (2008),<br></p>

<p>Applications Thiometon-sulfone is a metabolite from Thiometon (D231370) pesticides, used as an insecticide. Cholinesterase inhibitor.<br>References Edson, E.F., et al.: Pharm. J., 185, 365 (1960); Pozo, O., et al.: Anal. Bioanal. Chem., 389, 1765 (2007); Mezcua, M., et al.: Anal. Chem., 81, 913 (2009);<br></p>

<p>Stability Hygroscopic<br>Applications Kasugamycin Hydrochloride is an aminoglycoside antibiotic that inhibits the initiation of translation. It is also a type of fungicide that controls leaf and neck blast disease caused by Pyricularia oryzae and increases rice yields.<br>References Okuyama, A., et al.: J. Antibiot., 28, 903 (1975); Shinabarger, D., et al.: Antimicrob. Agents Chemother., 41, 2132 (1997); Reddy, A., et al.: Pesticides, 22, 21 (1988);<br></p>

<p>Applications Dabigatran-d7, is the labeled analogue of Dabigatran (D100090), Nonpeptide, direct thrombin inhibitor. Antithrombotic.<br>References Hauel, N., et al.: J. Med. Chem., 45, 1757 (2002), Mungall, D., et al.: Curr. Opin. Invest. Drugs, 3, 095 (2002), Stangier, J., et al.: J. Clin. Pharmacol., 45, 555 (2005),<br></p>

<p>Stability Hygroscopic, Light Sensitive, Moisture Sensitive, Temperature Sensitive<br>Applications trans-Deltamethrin, is trans isomer of Deltamethrin (D230700), a synthetic pyrethroid insecticide, which acts as a potent inhibitor of calcineurin (protein phosphatase 2B) and has an IC50 of about 100pM.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kavlock, R., et al.: J. Environ. Pathol. Toxicol., 2, 751 (1979), Enan, E., et al.: Biochem. Pharmacol., 43, 1777 (1992), Tan, J., et al.: Mol. Biol., 32, 445 (2002);<br></p>

<p>Applications Pantoprazole-d3 is the labeled analogue of Pantoprazole, an antiulcerative. Gastric pump inhibitor.<br>References Simon, W.A., et al.: Biochem. Pharmacol., 39, 1799 (1990)<br></p>

<p>Applications Dalfampridine is used in characterizing subtypes of potassium channel, and has also been used to manage some of the symptoms of multiple sclerosis, and is indicated for symptomatic improvement of walking in adults with several variations of the disease. Dalfampridine is a precursor to the drug Pinacidil.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Judge S., et al.: Pharmacol. Ther., 111, 224 (2006), Wu, Z.Z., et al.: J. Biol. Chem., 284. 36453 (2009),<br></p>

<p>Applications Astragaloside IV has cardiovascular protective effects, protecting the vascular endothelial cells. In addition it is attributed to have anti0inflammatory and anti-virus effects as well. This is due to its scavenging ability of oxygen free radicals, regulation of mineral homeostasis and antioxidative effects.<br>References Liu, S. et al.: J. Chinese Pharm. Sci., 22, 222 (2013);<br></p>

<p>Applications Dichlobentiazox is a pesticide.<br>References Tanaka, R., et al.: From PCT Int. Appl. (2017), WO 2017170792 A1 20171005; Reinhard, R., et al.: From PCT Int. Appl. (2020), WO 2020169414 A1 20200827<br></p>

<p>Applications 3-Phenoxybenzoic Acid, can be used in the preparation of widely used insecticides, such as Permethrin (P288500). which is a synthetic chemical, used as an insecticide, acaricide, and insect repellent.<br>References Elliott, M., et al.: Nature, 246, 169 (1973); Zheng, M., et al.: Zhongguo Ertong Baojian Zazhi, 20, 409 (2012);<br></p>

<p>Applications Velpatasvir is a NS5A inhibitor in patients with hepatitis C (HCV) infection.<br>References Gane, E. J., et al.: Gastroenterol., 151, 448 (2016); Feld, J. J., et al.: N. Engl. J. Med. 373, 2599 (2015);<br></p>

<p>Applications Plocloraz is used as a fungicide. Plocloraz showed efficacy against cereal powdery mildew.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Riviere, J.-L., et al.: Pestic. Sci., 15, 317 (1984), Debrauwer, L., et al.: J. Agric. Food Chem., 49, 3821 (2001),<br></p>

<p>Applications Flubromazepam is a designer benzodiazepine drug structurally related to Phenazepam (P295300); a drug used in the treatment of neurological disorders such as epilepsy, alcohol withdrawal and insomnia. Phenazepam (P295300) can also be used as a premedication before surgery as it augments the effects of anesthetics and reduces anxiety.<br>References Moosmann, B., et al.: J. Mass Spectrom., 48, 1150 (2013); Ogiso, T., et al.: Chem. Pharm. Bull., 37, 446 (1989); Gu, Q., et al.: J. Med. Chem., 36, 1001 (1993); Bekhterev, V.N., et al.: Pharm. Chem. J., 42, 95 (2008)<br></p>

<p>Applications Penicillin DF Potassium Salt, is used to characterize phenylacetate-CoA ligase from Penicillium chrysogenum.<br>References Koetsier, M., et al.: Biochem. J., 417, 467 (2009);<br></p>

<p>Stability Moisture Sensitive, unstable in solution<br>Applications 4-Hydroxy Diclofenac acyl glucuronide is a derivative of Diclofenac (Sodium Salt: D436450). Diclofenac is the first non-steroidal anti-inflammatory drug (NSAID) that is derived from phenylacetic acid. Diclofenac, like other NSAIDs, primarily works by targeting the cyclo-oxygenase pathway in the arachidonic acid cascade, reducing the formation of inflammation mediators in the body.<br>References Ku, E., et al.: Am. J. Med., 80, 18 (1986); Simmons, D., et al.: Proc. Nat. Acad. Sci., 96, 3275 (1999); Small, R.: Clin. Pharm., 8, 545 (1989)<br></p>

<p>Applications Aldicarb is used as an insecticide. Used in Pesticide detection. Useful in cannabis testing kits as a component of pesticide mixes (P698240).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ashby, J., et al.: Environ. Mutagen., 7, 919 (1985), Ashby, J., et al.: Mutat. Res., 257, 229 (1991), Kazius, J., et al.: J. Med. Chem., 48, 312 (2005), Benigni, R., et al.: Mutagenesis, 25, 335 (2010),<br></p>

<p>Stability Hygroscopic<br>Applications A phenethylamine derivative as sympathomimetics. Adrenergic.<br>References Lee, P., et al.: Mol. Pharmacol., 4, 498 (2007), Coan, K., et al.: J. Med. Chem., 52, 2067 (2009),<br></p>

<p>Applications Cymoxanil is a fungicide applied as a seed treatment or as a foliar application to the plants to control late blight.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Dhingani, J. C., et al.: J. Pure. App. Microbiol., 6, 1683 (2012); Bakirici, G.T., et al.: Food. Chem., 135, 1901 (2012);<br></p>

<p>Applications Octopamine-13C2,15N Acetic Acid is the salt form of Octopamine-13C2,15N(O239752). Labelled Octopamine (O239750). A biogenic amine that is the phenol analog of Noradrenaline. It is a neurosecretory product found in several vertebrates and invertebrates. Adrenergic.<br>References Pisano, et al.: Biochim. Biophys. Acta., 43, 566 (1960), Breen, C.A., et al.: Nature, 303, 716 (1983);<br></p>

<p>Applications 3-(2,2-Dichloroethenyl)-2,2-dimethylcyclopropanecarboxylic Acid is a reagent used in the preparation of hapten and immunogen for the production of polyclonal antibodies, specific to Cypermethrin (C989000).<br>References Lee, N. et al.: J. Agri. Food Chem., 46, 520 (1998); Hongsibsong, S. et al.: Int. J. Agri. Biol., 14, 246 (2012);<br></p>

<p>Applications The main labelled metabolite of o-xylene.<br>References Gregus, Z., et al.: Drug Metab. Dispos., 26, 1082 (1998), Gregus, Z., et al.: Xenobiotica, 29, 547 (1999), Gonzalez-Reche, L., et al.: Arch. Toxicol., 77, 80 (2003),<br></p>

<p>Stability Air Sensitive<br>Applications 7-Hydroxycitronellal shows fungicide activity the strains of Candida tropicalis.<br>References Filho, O., et al.: Bioscience Journal, 33, 204 (2017)<br></p>

<p>Applications Labelled Ethambutol. Antibacterial (tuberculostatic).<br>References Wilkinson, et al.: J. Med. Chem., 5, 835 (1962), Kulig, et al.: Diss. Pharm. Pharmacol., 23, 463 (1971), Lee, C.S., et al.: Anal. Profiles Drug Subs., 7, 231 (1978)<br></p>

<p>Stability Hygroscopic<br>Applications Decarboxy Cilastatin is an impurity in the synthesis of Cilastatin (C441100), prevents renal metabolism of penem and carbapenem antibiotics by specific and reversible dehydropeptidase I inhibition. Antibacterial adjunct.<br>References Finlay, K.R., et al.: Invest. Ophthalmol. Visual Sci., 24, 1147 (1983), Norrby, S.R., et al.: Antimicrob. Agents Chemother., 23, 300 (1983), Washburn, D.E., et al.: J. Antimicrob. Chemother., 12, 39 (1983),<br></p>

<p>Applications Labelled Fenpropimorph (F249500). Systemic fungicide for control of powdery mildew, rust in cereal crops.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Baloch, R.I., et al.: Phytochemistry, 23, 2219 (1984), Pommer, E.-H., et al.: Pestic. Sci., 15, 285 (1984),<br></p>

<p>Applications Carfentrazone-ethyl is a triazolone herbicides and is a derivative of Carfentrazone (C183465). Carfentrazone-ethyl was found to be suitable against complex weed flora in wheat.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bhullar, M.S., et al.: Crop. Protect., 43, 216 (2013); Malik, R.S., et al.: Environ. Ecol., 30, 717 (2012);<br></p>

<p>Applications Analgesic and anti-inflammatory compound.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Cochin, J., et al.: J. Pharmacol. Exp. Ther., 139, 160 (1963),<br></p>

<p>Applications An agonist to both GHB and GABAB neural receptors, exhibiting neurotransmitter-like effects. It has been used as a general anesthetic in treatment for sleep disorders and clinical depression, but also has been identified as a “date rape drug”.<br>References Mamelak, M., et al.: Prog. Neurobiol., 89, 193 (2009), Zhang, L., et al.: App. Microbiol. Biotechnol., 84, 909 (2009), Pedraza, C., Int. J. Neuropsychopharmacol., 12, 1165 (2009), McGonigle, I., et al.: Biochem., 49, 2897 (2010),<br></p>

<p>Applications Indoleacetic Acid is the most common and naturally occuring plant hormone in the auxin class of hormones. It effects cell elongation, cell division as well as plant growth and development.<br></p>

<p>Applications Chlorfluazuron is benzoyl(pyridiyloxyphenyl)urea based pesticide that acts as a chitin synthesis inhibitor. Chlorfluazuron is commonly used in agriculture as an insect growth regulator for controlling the major insect pests in crops<br>References Perveen, F.: J. Life Sci., 5, 933 (2011); Elek, J.A.: Entomol. Exp. Appl., 88, 31 (1998); Osbrink, W.L.A. et al.: J. Econ. Entomol., 104, 1009 (2011);<br></p>

<p>Applications Used as a reference standard for the drug Trimethoprim.Note this compound is a cis / trans mixture.<br></p>

<p>Applications 2-(1h-1,2,4-Triazol-1-Yl)Acetic Acid (cas# 28711-29-7) is a useful research chemical.<br></p>

<p>Applications A labelled antihypertensive. An angiotensin converting enzyme (ACE) inhibitor, converted to active, diacid metabolite.<br>References Teetz, V., et al.: Arzneim.-Forsch., 34, 1399 (1984), Ruggenenti, P., et al.: Lancet, 352, (1998), Bosch, J., et al.: Br. Med. J., 324, 1 (2002),<br></p>

<p>Applications 9,10-Dihydroergocristine Methanesulfonate is an nontoxic and well tolerated drug that exerts agonistic and antagonistic activity on dopaminergic and adrenergic receptors. 9,10-Dihydroergocristine Methanesulfonate is known to exhibit protective properties to the brain against metabolic effects of ischemia by acting at a cellular level.<br>References Setti, M., et al.: Angiologia., 30, 98 (1978); Brunhofer, G., et al.: Bioorg. Med. Chem., 20, 6669 (2012); Benzi, G., et al.: Neurobiol. Aging., 9, 371 (1988);<br></p>

<p>Applications 2,4,5-Trichlorophenoxyacetic Acid is suitable for plant cell culture testing. Post-emergence herbicide.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Smith, J., et al.: Science, 203, 1090 (1979), Salunkhe, C., et al.: Plant Cell Reports, 18, 670 (1999), Jheng, F., et al.: Plant Sci., 170, 1133 (2006),<br></p>

<p>Applications An N-alkylated Amphetamine (A634240) derivative. It shows the same toxicokinetic activity as amphetaminil, benzphetamine, clobenzorex, dimethylamphetamine, ethylamphetamine, famprofazone, fencamine, fenethylline, fenproporex, mefenorex, mesocarb, methamphetamine (M258785), prenylamine, and selegiline (D288641).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hiramatsu, M., et al.: J. Pharmacol. Exp. Ther., 254, 521 (1990), Lin, L., et al.: Drug Metab. Dispos., 25, 1059 (1997), Wu, D., et al.: Biochem. Pharmacol., 53, 1605 (1997),<br></p>

<p>Applications Phenkapton is an antiparasitic agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rico, A., et al.: Environ. Toxicol. Chem., 35, 494 (2016), Bai, G., et al.: Lihua Jianyan, Huaxue Fence, 49, 835 (2013)<br></p>

<p>Applications (+)-trans-Allethrin is a synthetic pyrethroid derivative used as an insecticide. Allethrin is commonly used in many household insecticide products due to its low toxicity towards humans. Pesticide component.Environmental toxin on US EPA Toxic Release Inventory list (TRI) list.<br>References Chatterjee, N. et al.: Food. Chem., 196, 1 (2016);<br></p>

<p>Applications Methabenzthiazuron is a benzothiazole and urea based herbicide used to control a spectrum of broad-leaved weeds and grasses crops. Methabenzthiazuron works via the inhibition of photosynthetic electron transport chain.<br>References Dalkmann, P., et al.: Environ. Toxicol. Chem., 31, 556 (2012);<br></p>

<p>Applications Isotope labelled Bis(2-chloroethyl)amine is a cytotoxic metabolite of Cyclophosphamide; a deuterated analog of Nor-nitrogen mustard.<br>References Colvin, M., et al.: Cancer Res., 36, 1121 (1976), Ludeman, S., et al.: Drug Metab Dispos., 20, 337 (1992), Ludeman, S.M., et al.: J. Pharmaceut. Sci., 84, 393 (1995), Yu, L., et al.: Drug Metab. Dispos., 24, 1254 (1996),<br></p>

<p>Applications (R,S)-Equol 7-β-D-Glucuronide is a glucuronide metabolite of isoflavone Daidzein (D103500).<br>References Heinonen, S., et al.: Anal. Biochem., 274, 211 (1999), Setchell, K., et al.: J. Nutr., 132, 3577 (2002), Thigpen, J., et al.: Comp. Med., 53, 607 (2003), Yee, S., et al.: Food Chem. Toxicol., 46, 2713 (2008)<br></p>

<p>Applications Fluopyram is a succinate dehydrogenase inhibitor (SDHI) used as a fungicide. It is also useful in cannabis testing kits as a component of pesticide mixes (P698240).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Amiri, A. et. al.: Plant Disease, 98, 532 (2014); Ishii, H., et. al.: Pest. Manag. Sci., 67, 474 (2011)<br></p>

<p>Applications A labelled form of Pirimicarb (P508768) which is a pesticide which is useful in cannabis testing kits as a component of pesticide mixes (P698240).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Tsuchiyama, T.; et al.: Journal of Chromatography A, 1524, 233 (2017).<br></p>

<p>Stability Unstable in Solution<br>Applications Dabigatran Acyl-β-D-Glucuronide Trifluoroacetic Acid Salt is a major metabolite of Dabigatran (D100090) in humans. Four isomeric acylglucuronides of Dabigatran were isolated and purified from urine of dosed rhesus monkeys.  NMR analysis confirmed the structures of the four metabolites as the 1-O-acylglucuronide (β anomer) and the 2-O-, 3-O-, and 4-O-acylglucuronides (α and β anomers).<br>References Becker, B., et al.: Biochem. J., 314, 249 (1996), Bailey, M., et al.: Chem. Biol. Interact., 145, 117 (2004), Blech, S., et al.: Drug Metab. Dispos., 2008, 36, 386 (2008),<br></p>

<p>Applications Testosterone (T155000) derivative. Intermediate in the preparation of Epostane (E588850).<br></p>

<p>Applications Labelled Intedanib (I666650). It is an indolinone derivative potently blocking VEGF-, PDGF-, and FGF-receptor kinases; an indolinone as triple angiokinase inhibitors. An antitumor agent.<br>References Sun, L., et al.: J. Med. Chem., 41, 2588 (1998), Xie, H., et al.: J. Med. Chem., 50, 4898 (2007), Hilberg, F., et al.: Cancer Res., 68, 4774 (2008),<br></p>

<p>Applications 1,2,4-Triazolo[3,4-b]benzothiazole-5-methanol is the major alcohol metabolite of tricyclazole (T291465) which is an common active ingredient in several commercial fungicide products used to control rice blast fungus, in transplanted and direct-seeded rice.<br>References Koons, J., et al.: J. Agri. Food Chem., 33, 552 (1985)<br></p>

<p>Applications Synthetic mu-opioid agonist. This is a controlled substance (opiate).<br>References James, M.K., et al.: J. Pharmacol. Exp. Ther., 259, 712 (1991), Hoffman, W.E., et al.: Anesthesiology, 79, 107 (1993), Selinger, K., et al.: J. Pharm. Biomed. Anal., 12, 243 (1994), Richardson, T.D., et al.: Expert Opin. Drug Saf., 4, 643 (2005),<br></p>

<p>Stability Hygroscopic<br>Applications Labelled dimethyl phosphorothiolate derivatives used as insecticides.<br>References Suzuki, F., et al.: Jpn. Tokkyo Koho (1976), JP 51009007 B<br></p>

<p>Applications A metabolite of Naproxen.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rettie, A., et al.: Chem. Res. Toxicol., 5, 54 (1992), Tracy, T., et al.: Biochem. Pharmacol., 52, 1305 (1996), Bonnabry, P., et al.: Eur. J. Clin. Pharmacol., 49, 305 (1996), Rao, S., et al.: J. Med. Chem., 43, 2789 (2000), Hutzler, J., et al.: Drug Metab. Dispos., 29, 1029 (2001),<br></p>

<p>Applications Coproporphyrin III can be used as a biomarker for environmental toxicity and susceptibility in autism.<br>References Geier, D. A., et al.: J. of the Neuro. Sci., 280(1-2), 101-108 (2009)<br></p>

<p>Applications N-Acetyl Mesalazine-d3 is the labeled analogue of N-Acetyl Mesalazine (A168320), a metabolite of Mesalazine. A Salicylic Acid derivative. Inhibitor of recombinant human thiopurine methyltransferase (hTPMT).<br>References Bondesen, S., et al.: Br. J. Clin. Pharmacol., 25, 269 (1988); Brogden, R., et al.: Drugs, 38, 500 (1989); Jensen, J., et al.: Biochem. Pharmacol., 45, 1201 (1993); Liu, Z., et al.: Drug Metab. Dispos., 23, 246 (1995); Vree, T., et al.: Clin. Drug Invest., 20, 35 (2000)<br></p>

<p>Applications Controlled substance (depressant). Anxiolytic. Prototype of the benzodiazepine anxiolytics.<br>References MacDonald, A., et al.: Anal. Profiles Drug Subs., 1, 15 (1972); Greenblatt, D.J., et al.: Clin. Pharmacokinet., 3, 381 (1978);<br></p>

<p>Stability Moisture Sensitive<br>Applications Fenchlorphos-oxon is a pesticide residue found in fruits and vegetables.<br>References Jadhav, M.R., et. al.: J. Agr. Food Chem., (Ahead of Print) (2015); Li, Y. et. al.: J. Chromatogr. A., 1361, 77 (2014); Li, X., et. al.: Sepu, 32, 268 (2014)<br></p>

<p>Applications Colinesterase inhibitor. Insecticide.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gaines, T.B., et al.: Toxicol. Appl. Pharmacol., 14, 515 (1969),<br></p>

<p>Applications 3-Hydroxykynurenine is a metabolite of tryptophan. 3-Hydroxykynurenine filters UV light in the human lens. Studies suggest that Hydroxykynurenine is an endogenous oxidative stress generator and a potential endogenous neurotoxin.<br>References Malina, H.Z. et al.: Graefes. Arch. Clin. Exp. Ophthalmol., 233, 38 (1995); Okuda, S. et al.: J. Neurochem., 70, 299 (1998);<br></p>

<p>Applications BUTAN-2-YL 4-HYDROXYBENZOATE (cas# 17696-61-6) is a useful research chemical.<br></p>

<p>Applications Hexadecyl Acetate is a plant sex pheromone.<br>References Brasero, N., et al.: J. Chem. Ecol., 44, 9 (2018); Cuervo, M., et al.: J. Chem. Ecol., 43, 469 (2017)<br></p>

<p>Applications Pretilachlor is a chloroacetanalide herbicide. Pretilachlor is commonly used for weed control in wet seeded rice<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mohankumar, P.D. et al.: J. Trop. Agric., 34, 149 (34, 149 (1996); Ravisankar, N. et al.: Ind. J. Agron., 53, 57 (2008); Singh, S. et al.: Crop Prot., 27, 660 (2008);<br></p>

<p>Applications (E)-Fenpyroximate is an acaricide and an inhibitor of mitochondrial electron transport at Complex I.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hamedi, N. and Fathipour, Y.: BioControl 55, 271 (2010); Sato, M. E., et al.: Appl. Entomol. Zool. 39, 293 (2004)<br></p>

<p>Applications 5-Desthiopropyl-5-hydroxy-ticagrelor is a related compound of ticagrelor (T437700). Ticagrelor, the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Used in the treatment of acute coronary syndromes (ACS).<br>References Matetzky, S., et al.: Circulation, 109, 3171 (2004), Bassand, J., et al.: Eur. Heart J., 28, 1598 (2007), Jakubowski, J., et al.: Cardiovasc. Drug Rev., 25, 357 (2007),<br></p>

<p>Applications It is a parasympathomimetic, specifically, a reversible cholinesterase inhibitor obtained from the Calabar bean, used to treat glaucoma and delayed gastric emptying.<br>References Engelhart, L., et al.: Arch. Exp. Pathol. Pharmakol., 150, 1 (1930), Muhtadi, F.J., et al.: Anal. Profiles Drug Subs., 18, 289 (1989),<br></p>

<p>Applications Labelled Diltiazem (D460620). A calcium channel blocker with vasodilating activity. Antianginal; antihypertensive; antiarrhythmic (class IV).<br>References Sato, et al.: Arzneim.-Forsch., 21, 1338 (1971), Smirnov, S.R.: Eur. J. Pharmacol., 360, 81 (1998), Hansson, L., et al.: Lancet, 356, 359 (2000),<br></p>

<p>Applications Desmedipham is a carbanilate based herbicide used in the weed control programs in sugar beet.<br>References Kittlaus, S., et al.: J. Chromatograph. A., 1283, 98 (2013); Wujek, B., et al.: J. Food. Agri. Environ., 10, 606 (2012);<br></p>

<p>Stability Hygroscopic<br>Applications Ticagrelor, the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Used in the treatment of acute coronary syndromes (ACS).<br>References Matetzky, S., et al.: Circulation, 109, 3171 (2004), Bassand, J., et al.: Eur. Heart J., 28, 1598 (2007), Jakubowski, J., et al.: Cardiovasc. Drug Rev., 25, 357 (2007),<br></p>

<p>Applications Steroid hormone with weak androgenic effects.<br>References Wartman, C., et al.: Aquatic Toxicol., 92, 131 (2009), Gohil, V., et al.: Nat., Biotechnol., 28, 249 (2010), Phapale, P., et al.: Clin. Pharmacol. Ther., 87, 426 (2010),<br></p>

<p>Applications Chlorfenapyr-d7 is the labelled analogue of Chlorfenapyr (C428500), which is a halogenated pyrrole based pro-insecticide. Chlorfenapyr functions by metabolizing into an active insecticide after entering the host. Chlorfenapyr is used primarily as a means of pest control on cotton. Used as a standard for Pesticide detection. Chlorfenapyr is also useful in cannabis testing kits as a component of pesticide mixes (P698230).<br>References Lovell, J.B. et al.: Bright. Crop Prot. Pests Dis., 1, 37 (1990); Wier, A.T. et al.: J. Agric. Entemol., 11, 311 (1994); Black, B.C. et al.: Pest. Biochem. Physiol., 50, 115 (1994);<br></p>

<p>Stability Very Moisture Sensitive<br>Applications Chlorotriphenylstannane is used in the synthesis of nanoparticles which bear triamide ligands.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Shariatinia, Z. et al.: Beil. J. Nanotech., 4, 94 (2013);<br></p>