Compuestos y reactivos bioquímicos

A synthetic peptide for use as a blocking control in assays to test for specificity of CLPTM1L antibody, catalog no. 70R-7327

CD79b antibody (PE) was raised in hamster using the beta chain of the murine B-cell receptor as the immunogen.

SB-649868 is a drug in clinical development for the treatment of sleep-wake disorders. It is a potent and selective allosteric modulator of the GABAA receptor, with a profile that includes high affinity for the α1β2γ2 subtype. SB-649868 has been shown to increase slow wave sleep and delta power during wakefulness in healthy human subjects. SB-649868 has also been shown to have no effect on blood pressure or heart rate at clinically relevant doses, suggesting reduced risk for cardiovascular side effects.
SB-649868 was well tolerated in preclinical studies, without serious adverse events observed.

A synthetic peptide for use as a blocking control in assays to test for specificity of CAPNS2 antibody, catalog no. 70R-10067

BIBP 3226 is a drug that belongs to the class of beta-blockers. It is a potent and selective beta-adrenergic receptor antagonist that has been shown to have maximal response in the concentration range of 1 nM to 10 micromolar. The effects on blood pressure are dose dependent, with a maximal effect at doses greater than or equal to 0.1 mg/kg. BIBP 3226 has been found to inhibit insulin resistance and increase cardiac contractility in rats, and may also have an inhibitory effect on platelet aggregation. This drug exhibits pharmacokinetic properties that are independent of food intake and is metabolized by CYP3A4 in the liver.

A synthetic peptide for use as a blocking control in assays to test for specificity of SESN2 antibody, catalog no. 70R-10132

CDK3 antibody was raised in rabbit using the C terminal of CDK3 as the immunogen

Inhibitor of proton pump

Anti ACTH (1-23) (Rat) Serum is a recombinant peptide that is an activator of the hypothalamus. It has been shown to have a high affinity for the receptor, and it can be used as a research tool in cell biology and pharmacology. Anti ACTH (1-23) (Rat) Serum is used in the study of ion channels, ligands, and antibodies. This peptide has been used to inhibit the release of ACTH from the pituitary gland and can be used to study the effects of anti-ACTH on other hormones. Anti ACTH (1-23) (Rat) Serum is purified from E. coli cells with a CAS number of 58612-37-8.

Amyloid β (42- 1) SCR is a peptide that inhibits the interaction of amyloid β with its receptor, which may be useful for research purposes. Amyloid β (42- 1) SCR is an inhibitor that prevents the binding of amyloid β to its receptors. This peptide is a high purity product and has been shown to be effective in inhibiting the interaction between amyloid beta and its receptor.

2-(2-Ethylaminobenzylsulfinyl)-5,6-dimethoxybenzimidazole is a potent inhibitor of the human erythrocyte acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). This inhibitor binds to the active site of both enzymes. The IC50 for AChE inhibition is about 5 nM and for BChE inhibition is about 1 μM. 2-(2-ethylaminobenzylsulfinyl)-5,6-dimethoxybenzimidazole has been shown to be an activator of protein interactions in a cell-free system. It also has been used as a ligand in receptor binding assays. In addition, this inhibitor can be used as a research tool to study ion channels and antibodies.

APYTFGQGTK peptide is a sequence from light chain of Adalimumab monoclonal antibody. Due to its universal location in Adalimumab antibody, APYTFGQGTK is used as a specific signature peptide for the quantitation of Adalimumab. Indeed, proteomic studies allows quantification of proteins in blood samples.
What is Adalimumab?
Adalimumab corresponds to a therapeutic monoclonal antibody. It is a subcutaneously administered biological disease modifier for the treatment of rheumatoid arthritis and other chronic debilitating diseases mediated by tumor necrosis factor. This drug is frequently known as Humira.

Gadolinium(III) bromide is a salt of gadolinium with the chemical formula GdBr3. It is a colorless solid that can be obtained as long, needle-like crystals. Gadolinium(III) bromide is used to produce a variety of gadolinium compounds, such as gadopentetate dimeglumine, which is used for MRI contrast enhancement. The compound's vapor pressure is 1.5 x 10-4 torr at room temperature and its evaporation point is 292 °C (550 °F).

Gadolinium(III) bromide has been shown to have replicating properties in experimental systems. These properties are determined by the size of the system and the parameters involved in the reaction yield, transition state, and stoichiometry.

A synthetic peptide for use as a blocking control in assays to test for specificity of AHCY antibody, catalog no. 70R-2721

CD 2314 is an innovative compound used as a neuromodulatory agent, derived from advanced synthetic pathways. This compound acts selectively on specific neural receptors through ligand-receptor interactions, making it a valuable tool for elucidating complex neurological pathways. By modulating synaptic transmission and influencing neurotransmitter release, CD 2314 offers potential insights into the synaptic mechanisms underpinning cognitive processes.

Rabbit polyclonal EPHB2 antibody (Tyr298)

TRAF-STOP inhibitor 6877002 is a molecule inhibitor that inhibits the activity of signalling molecules in chronic inflammation, atherosclerosis, and cardiac hypertrophy. TRAF-STOP inhibitor 6877002 is an inhibitor group that blocks the signalling pathways involved in cardiac function. It has been shown to inhibit cardiac hypertrophy by inhibiting the signaling pathways mediated by TNF-α, IL-1β, and IL-6. This drug also reduces systolic dysfunction in heart failure patients with reduced ejection fraction by suppressing myocardial fibrosis.

Zatebradine hydrochloride is a drug which is used to treat bowel disease. It belongs to the class of drugs known as beta-blockers. Zatebradine hydrochloride can be administered intravenously and has been shown to cause a decrease in heart rate and ventricular function in humans. It also has an effect on energy metabolism, cardiac effects, and structural heart disease. This drug has been found to be effective at treating congestive heart failure and atrial fibrillation. Zatebradine hydrochloride also has anti-inflammatory properties that may be due to its ability to inhibit the production of inflammatory cytokines such as IL-1β, IL-6, TNFα, IL-8, and IFNγ.