Compuestos y reactivos bioquímicos

<p>WS-12 is a low-potency antimicrobial agent that inhibits bacterial growth by disrupting the microbial membrane and cell wall. WS-12 is an aryl halide with a cationic side chain that binds to activated filaments, which disrupts the function of the cell membrane. The exact mechanism of how WS-12 interacts with cells is not known, but it has been shown to alter neuronal function, cause growth inhibition in cancer cells, and inhibit the polymerase chain reaction.</p>

<p>PKI-tide is a potent, selective inhibitor of the calcium/calmodulin-dependent protein kinase. It inhibits the activity of this enzyme and prevents the activation of other protein kinases by this enzyme. PKI-tide binds to the ATP site of the calcium/calmodulin-dependent protein kinase and blocks the binding of ATP and calmodulin. This inhibition prevents the phosphorylation of target proteins, including myosin light chain in muscle cells.</p>

<p>H-Glu(Glu(Glu-OH)-OH)-OH trifluoroacetate salt is a casein that is used as a model system for pancreatic β-cells. It has been shown to induce cell apoptosis in malignant cells and sequences that are associated with the development of pancreatic cancer. H-Glu(Glu(Glu-OH)-OH)-OH trifluoroacetate salt also induces endothelial cell proliferation and decreases cell function, which may be due to its ability to promote uptake of this compound.</p>

<p>Catalogue peptide; min. 95% purity</p>

<p>Catalogue peptide; min. 95% purity</p>

<p>Calcium Dobesilate Hydrate is a pharmaceutical compound, which is a synthesized chemical derived from dobesilic acid. It functions primarily as a vasoprotective agent, reducing vascular permeability and stabilizing capillary walls by inhibiting platelet aggregation and the release of free radicals. This results in decreased capillary fragility and improved blood flow in microcirculatory systems.</p>

<p>CIN16645 is a peptide inhibitor of protein interactions. It has been shown to bind to the receptor and inhibit the activation of ion channels, which are proteins that form pores in cell membranes to allow ions to pass through. CIN16645 is a ligand for the receptor and can be used as a research tool for studying ion channels. The purity of this product is high, with no detectable impurities. This product is intended for use in life sciences research applications, such as antibody production and cell biology research.</p>

<p>Catalogue peptide; min. 95% purity</p>

<p>Catalogue peptide; min. 95% purity</p>

<p>Please enquire for more information about Uroguanylin Topoisomer B (human) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Catalogue peptide; min. 95% purity</p>

<p>Please enquire for more information about N-(3-Amino-2-hydroxy-3-oxopropyl)-L-valyl-N-phenyl-L-leucinamide including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Catalogue peptide; min. 95% purity</p>

<p>Catalogue peptide; min. 95% purity</p>

<p>Catalogue peptide; min. 95% purity</p>

<p>Catalogue peptide; min. 95% purity</p>

<p>Mots-C acetate salt form</p>

<p>Catalogue peptide; min. 95% purity</p>

<p>Catalogue peptide; min. 95% purity</p>

<p>Catalogue peptide; min. 95% purity</p>

<p>YK11 is a synthetic gene-selective androgen receptor modulator, which is derived from steroidal structures and designed to modulate specific pathways. This compound is characterized by its unique ability to act as a partial agonist/antagonist at the androgen receptor, with a focus on inhibiting the activity of myostatin, a regulatory protein that limits muscle growth.</p>

<p>Catalogue peptide; min. 95% purity</p>

<p>Catalogue peptide; min. 95% purity</p>

<p>Catalogue peptide; min. 95% purity</p>

<p>Catalogue peptide; min. 95% purity</p>

<p>Catalogue peptide; min. 95% purity</p>

<p>Catalogue peptide; min. 95% purity</p>

<p>Catalogue peptide; min. 95% purity</p>

<p>CJC-1295-no DAC acetate is a synthetic peptide, which is a modified form of the growth hormone-releasing hormone (GHRH) analog, derived from recombinant sources. Its mode of action involves binding to the growth hormone secretagogue receptor, thereby promoting the release of growth hormone from the anterior pituitary. This mechanism of action facilitates the increase of circulating insulin-like growth factor 1 (IGF-1), enhancing various physiological processes.In scientific research, CJC-1295-no DAC acetate is primarily utilized to study its potential effects on muscle growth, body composition, and overall metabolic function. It is also used to explore its ability to modulate the aging process through growth hormone pathways. Unlike its counterpart with DAC, this variant has a shorter half-life, thus allowing researchers to examine the temporal effects of pulsatile GH release. Furthermore, its applications extend to understanding disorders related to growth hormone deficiencies, contributing valuable insights into therapeutic strategies for such conditions. The peptide serves as an important tool in endocrinology research, providing a platform for studying the complex interactions between hormonal regulation and physiological outcomes.DAC is 'drug affinity complex' and in this peptide works by not having a lysine at the end of the sequence.</p>

<p>ARQ 531 is a small molecule inhibitor specifically designed to target Bruton's tyrosine kinase (BTK), which is a type of enzymatic protein. This compound is meticulously developed within a laboratory setting to disrupt key pathways involved in cancer cell survival. Its mode of action involves the selective and reversible inhibition of BTK, thereby obstructing signal transduction that promotes malignant cell proliferation and survival.</p>

<p>Catalogue peptide; min. 95% purity</p>

<p>N,N'-1,2-Ethanediylbis[N-[(2-hydroxyphenyl)methyl]-glycine is a research tool that is used to study the activation of receptors and ion channels. It can also be used to study protein interactions and pharmacology.</p>

<p>Catalogue peptide; min. 95% purity</p>

<p>Catalogue peptide; min. 95% purity</p>

<p>Please enquire for more information about (Met(O)35)-Amyloid b-Protein (25-35) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about ent-Amyloid b-Protein (1-42) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Catalogue peptide; min. 95% purity</p>

<p>Catalogue peptide; min. 95% purity</p>

<p>(1-Adamantaneacetyl1,D-Tyr(Et)2,Val4, Abu 6, Arg8·9)-vasopressin is a vasopressor analog that has been shown to be an effective treatment for congestive heart failure by acting as an agonist at the V1 receptor. It has been shown to stimulate cyclase activity and increase levels of adenosine 3',5'-cyclic monophosphate (cAMP). This drug also stimulates the production of immunoglobulin A antibodies in mice and increases the expression of leucine aminopeptidase and immunofluorescence in rat kidney cells. Vasopressin analogs are used primarily for their vasoconstrictive properties.</p>

<p>Please enquire for more information about Ac-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Ile-Glu-Thr-Asp-aldehyde trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Catalogue peptide; min. 95% purity</p>

<p>Please enquire for more information about Amyloid beta-Protein (1-46) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Catalogue peptide; min. 95% purity</p>

<p>Catalogue peptide; min. 95% purity</p>

<p>1-(7Z-Pentadecenoyl)-rac-glycerol is a glycerol derivative, which is typically synthesized or isolated from natural fats and oils. This compound is part of the monoacylglycerol family, characterized by a glycerol backbone esterified with a single fatty acid chain. The source of 1-(7Z-Pentadecenoyl)-rac-glycerol can be varied, stemming from enzymatic processes that occur in biological systems, or through chemical synthesis that mimics these natural interactions.</p>

<p>Catalogue peptide; min. 95% purity</p>

<p>Please enquire for more information about Fmoc-Ile-Wang resin (100-200 mesh) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Z-His(Bzl)-OH including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about HBsAg Mouse Monoclonal Antibody including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Dengue Virus Type 3 Envelope Antigen, Recombinant including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>TFA salt. Tripeptide containing hydroxyproline.</p>

<p>Please enquire for more information about Octreotide trifluoroacetate salt (Dimer, Antiparallel) ( including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Catalogue peptide; min. 95% purity</p>

<p>Catalogue peptide; min. 95% purity</p>

<p>Catalogue peptide; min. 95% purity</p>

<p>O-(3-Hexyl) dabigatran ethyl ester is an analog of dabigatran, a potent inhibitor of human thrombin. It has been shown to have anticancer properties by inducing apoptosis and inhibiting the cell cycle in Chinese hamster ovary cells. This compound has also demonstrated promising results in inhibiting tumor growth in mice with cancer. O-(3-Hexyl) dabigatran ethyl ester is a protein kinase inhibitor that may be useful as a medicinal agent for the treatment of cancer. Its bioavailability can be measured by analyzing urine samples to determine its pharmacokinetic profile. Overall, this compound shows great potential as an effective anticancer agent with further research needed for clinical applications.</p>

<p>Please enquire for more information about 5-TAMRA-Amyloid beta-Protein (1-42) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Amyloid beta-Protein (1-11) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>H-D-Phe-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-NH2 is a neuropeptide that was found in the brain of an amphibian and has been shown to have antinociceptive properties. The peptide has been shown to bind to kappa opioid receptors and δ opioid receptors, which are both involved in pain regulation. H-D-Phe-Cys-Tyr-D-Trp-Orn (HDFYDT) has been shown to be effective in vivo, which may be due to its ability to increase striatal dopamine levels and decrease locomotor activity. HDFYDT also increases gamma aminobutyric acid levels in the brain, which may result in reduced anxiety. HDFYDT is synthesized from two amino acids: histidine and glutamine. This peptide is sensitive to proteolytic enzymes and can be degraded into smaller fragments such</p>

<p>Please enquire for more information about Isovaleryl-Phe-Lys-pNA·HCl including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Catalogue peptide; min. 95% purity</p>

<p>Please enquire for more information about Tyr-Amyloid P Component (27-38) amide trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Arg-Glu(EDANS)-(Asn670,Leu671)-Amyloid beta/A4 Protein Precursor770 (668-675)-Lys(DABCYL)-Arg trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Mca-Amyloid beta/A4 Protein Precursor770 (667-676)-Lys(Dnp)-Arg-Arg amide trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Please enquire for more information about Amyloid beta/A4 Protein Precursor770 (586-595) (human, mouse, rat) trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Catalogue peptide; min. 95% purity</p>

<p>Please enquire for more information about Amyloid beta-Protein (17-40) ammonium salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Influenza PR8 Hemagglutinin Peptide (110-119) trifluoroacetate salt H-Ser-Phe-Glu-Arg-Phe-Glu-Ile-Phe-Pro-Lys-OH trifluoroacetate sa lt is a surface glycoprotein that has been shown to enhance the survival of neuronal cells. It is also involved in the regulation of energy metabolism and iron homeostasis, as well as in the induction of autoimmune diseases. This peptide contains a hydroxyl group, which can be oxidized by reactive oxygen species and may have neurotrophic effects. Trifluoroacetate salts of this protein are ester linkages that bind iron tightly and have been used for the treatment of iron overload.</p>

<p>JNJ16259685 is a metabotropic glutamate receptor antagonist that was developed as a potential drug target for the treatment of eye disorders. JNJ16259685 is an experimental model for pharmacological treatment of neuronal death and degeneration, and has been shown to decrease locomotor activity in experimental models. JNJ16259685 binds to the metabotropic glutamate receptor type 1 (mglur1) with high affinity and blocks the binding of glutamate to mglur1, which prevents neuronal death. JNJ16259685 has also been shown to be effective against ryanodine receptor-associated diseases by blocking the release of calcium from intracellular stores.</p>

<p>Lysine is an essential amino acid, which means that it cannot be synthesized by the body and must be obtained from food. It is a crucial component of many proteins, including enzymes and hormones. Lysine is also involved in calcium absorption, maintaining nitrogen balance, and the production of carnitine. Lysine hydrobromide is a salt form of lysine that can be used to inhibit protein synthesis in bacteria. This inhibition can take place at either the transcriptional or translational level, but not both simultaneously. The inhibition of protein synthesis prevents the cell from growing and reproducing. Lysine hydrobromide has been shown to have a regulatory effect on enzyme activities in corynebacterium glutamicum (a type of bacteria). It also acts as a substrate for uptake by corynebacterium glutamicum cells due to its high lysine content.</p>

<p>19-Epi FK-506 is an analog of the immunosuppressive drug FK-506 that has shown promise as an anticancer agent. It has been found to induce apoptosis in cancer cells, particularly in Chinese hamster ovary cells and leukemia cell lines. This compound is a potent inhibitor of protein kinases, which are involved in regulating cell growth and division. 19-Epi FK-506 has been identified as a potential medicinal agent for the treatment of various types of cancer due to its ability to inhibit tumor growth and proliferation. It is excreted in urine and may have therapeutic potential as a cancer inhibitor or in combination with other inhibitors.</p>

<p>Glutaryl-Phe-AMC is a fluorophore that has been used to study dental plaque. It is an amide of glutaryl-Phe and AMC, which is a water molecule. Glutaryl-Phe-AMC is a synthetic molecule that can be deprotonated by histidine in the presence of d-homoserine. The fluorescence of this compound increases when it binds to the enzyme substrates, 7-amino-4-methylcoumarin (AMC) and water molecules. This assay can be used for studying proteolytic activity on enzymes such as protease and amylase.</p>

<p>SAR125844 is a potent inhibitor of the tyrosine kinase activity of epidermal growth factor receptor (EGFR). It has been shown to inhibit tumor growth in animal models and inhibit cell proliferation in cancer cells. SAR125844 has been evaluated in clinical studies for the treatment of patients with prostate cancer, which is resistant to imatinib. The drug was found to be safe and well tolerated at doses up to 800 mg/day. Clinical response rates were observed in some patients who had experienced disease progression while on other therapies. SAR125844 inhibits tumor growth by targeting EGFR, which is an important cellular pathway that promotes cell proliferation and survival.</p>

<p>Alogliptin-1-oxo-1-de(piperidin-3-amine) is a potent anticancer agent that targets the cell cycle and induces apoptosis in cancer cells. It belongs to the class of medicinal inhibitors and acts as a kinase inhibitor, specifically targeting Chinese hamster ovary (CHO) cells and human cancer cells. Alogliptin-1-oxo-1-de(piperidin-3-amine) is an analog of a protein found in urine and has shown promising results in preclinical studies as an effective cancer treatment. Its ability to induce apoptosis in cancer cells makes it a valuable tool for researchers studying the mechanisms of cancer growth and development.</p>

<p>H-Phe-Val-OH, also known as humanized Val-Phe-His-Leu (VHL), is a monoclonal antibody that binds to the antigen epidermal growth factor (EGF). It has been shown to have diagnostic and therapeutic properties in vitro. This antibody is used in the diagnosis of cancer tissues and is able to identify carcinoma cell lines. Furthermore, it can be used to diagnose hepatitis C virus infection. H-Phe-Val-OH blocks the binding of EGF with its receptor on the surface of cells and prevents the proliferation of cancerous cells. It also inhibits cancer growth by reducing the synthesis of proteins such as epidermal growth factor and transforming growth factor alpha.</p>

<p>Please enquire for more information about Mca-(Asn670,Leu671)-Amyloid beta/A4 Protein Precursor770 (667-675)-Lys(Dnp) amide ammonium salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>(Asn7)-Amyloid b-Protein (1-40) trifluoroacetate salt H-Asp-Ala-Glu-Phe-Arg-His-Asn-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys<br>The product is a compound that has been shown to inhibit the formation of beta amyloid peptides in the brain. It binds to the beta amyloid peptide and prevents its aggregation, thereby preventing the formation of plaques and inhibiting neuronal cell death. The product contains no detectable levels of trehalose, which makes it ideal for use in brain imaging studies. This product may also be used as a predictive biomarker for Alzheimer's disease because it can be detected in cerebrospinal fluid and plasma.</p>

<p>BMY 7378 Dihydrochloride is a selective 5-HT1A receptor antagonist, which is synthetically derived for specialized research purposes. This compound is known for its ability to bind exclusively to the 5-HT1A receptor, inhibiting the action of serotonin. Its mechanism of action involves a high-affinity blockade of serotonin at this receptor site, making it a valuable tool for understanding serotonergic signaling pathways.</p>

<p>CX 5461 is a potent, selective inhibitor of the transcription elongation factor, polymerase (PEP). It binds to the PEP-DNA template complex and blocks dNTP incorporation into RNA. Studies in vitro show that CX 5461 inhibits cancer cell proliferation and induces autophagy and apoptosis. The drug also has genotoxic activity in vitro, as it inhibits DNA synthesis by inhibiting ribosome synthesis. CX 5461 has been shown to be effective against endometriosis in vivo as well as myeloma cells in vitro.</p>

<p>Catalogue peptide; min. 95% purity</p>

<p>H-Ile-Arg-OH acetate salt is an antioxidant that belongs to the group of amino acids. It has been shown to have antioxidative activity in vitro, as well as interaction with radicals and free radicals. Cryo-electron microscopy was used to show this compound's radical scavenging activity. H-Ile-Arg-OH acetate salt has also been found to have antioxidative properties in eukaryotes. This compound is composed of two isomers: H-Ile and Arg. The hydroxyl group on the H-Ile isomer gives this compound its antioxidative properties, while the Arg isomer possesses hydrolytic properties. The subunits are linked together by a peptide bond between the carboxyl group on Arg and the amine group on H-Ile. In addition, H-Ile has an -OH hydroxyl group that can be scavenged by hydroxyl radicals, which provides antioxidative activity.</p>

<p>Catalogue peptide; min. 95% purity</p>

<p>Catalogue peptide; min. 95% purity</p>

<p>Catalogue peptide; min. 95% purity</p>

<p>Please enquire for more information about Amyloid P Component (33-38) amide trifluoroacetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>Pigment Yellow 138 is a polycarboxylic acid with the chemical formula C8H6Cl4O2. Pigment Yellow 138 has a molecular weight of 434.07 and can be used as a yellow pigment in paint, plastics, and textiles. Pigment Yellow 138 has an acidic pH and can be prepared by reacting phthalic anhydride with sodium hydroxide in aqueous solution to produce the sodium salt of pigment yellow 138. Pigment Yellow 138 is also soluble in hydroxide solutions, which makes it an excellent cross-linking agent for polymers. The color of pigments depends on the size of their particles; pigments with larger particle sizes are more opaque than those with smaller particle sizes.</p>

<p>Catalogue peptide; min. 95% purity</p>

<p>Please enquire for more information about Trt-Glu(OtBu)-OH·DCHA including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>

<p>4-(5-Methanesulfonyl-(1,2,3,4)tetrazol-1-yl)-phenol is a potent inhibitor of kinases and proteins in humans that has been shown to have anti-cancer properties. It is an analog of neopterin, a biomarker for immune activation and oxidative stress. This compound has been found to induce apoptosis in cancer cells and inhibit the growth of tumors. The 4-(5-Methanesulfonyl-(1,2,3,4)tetrazol-1-yl)-phenol inhibitor has also been shown to be effective against Chinese hamster ovary cells and various other kinases. In addition, it has potential therapeutic applications as an anticancer agent due to its ability to inhibit the proliferation of cancer cells. This compound can also be detected in urine samples and may serve as a useful diagnostic tool for certain diseases or conditions.</p>