Building Blocks

Applications Ethyl 7-aminothieno[2,3-b]pyrazine-6-carboxylate

Applications Styrene-alpha,beta,beta-d3 (CAS# 3814-93-5) is a useful isotopically labeled research compound.

Applications 1,3-Propane-d6-sultone is a useful isotopically labeled compound of 1,3-Propanesultone (P760800)

Applications Sodium n-hexadecyl-d33 sulfate is labelled Sodium n-hexadecyl sulfate.It is an anionic surfactant.
References Nikas, Y., et al.: Langmuir, 10, 3512 (1994); Moradi, M., et al.: Talanta, 82, 1864 (2010)

Stability Hygroscopic
Applications N-Ethyl Benzamid-3-carboxylate is an impurity of DEET (D228500), which is an insect repellent.
References Gilbert, I.H., et al.: J. Econ. Entomol., 48, 741 (1955), Ambrose, A.M., et al.: Toxicol. Appl. Pharmacol., 1, 97 (1959), Blomquist, L., Acta Pharmacol. Toxicol., 41, 235 (1977), Yeung, J.M., et al.: Drug Metab. Dispos., 16, 600 (1988),

Applications Ethylbenzene-2,3,4,5,6-d5 (CAS# 20302-26-5) is a useful isotopically labeled research compound.

Applications 2-Oxo-2-(1-phenyl-1H-pyrazol-4-yl)acetic Acid is a derivative of N-Phenylpyrazole, a reactant in the synthesis of candesartan cilexetil(C175580), an ester prodrug; hydrolized in vivo to the active carboxylic acid. Used in treatment of congestive heart failure. Antihypertensive.
References Seki, M. et. al: ACS Catalysis, 4, 4047 (2014); Shibouta, Y., et al.: J. Pharmacol. Exp. Ther., 266, 114 (1993; Ogihara, T., et al.: Clin. Ther., 16, 74 (1994)

Applications Ethyl-alpha,alpha-d2-benzene-d5 (CAS# 84272-90-2) is a useful isotopically labeled research compound.

Applications N-SUCCINIMIDYL 6-MALEIMIDOHEXANOATE (cas# 55750-63-5) is a useful research chemical.

Applications DL-Methionine-2-d1 (CAS# 67866-74-4) is a useful isotopically labeled research compound.

Applications Glyceryl Tri(pentadecanoate-d29) (CAS# 352431-43-7) is a useful isotopically labeled research compound.

Applications 4-Nitrophenylacetonitrile is used as a radical inhibitor in the polymerization of vinyl acetate. Toxic compound to tetrahymena pyriformis.
References Foldes-Berezhnykh, T. et al.: Eur. Polym. J., 8, 1237 (1972); Cronin, M. et al.: Chem. Res. Tox., 14, 1498 (2001);

Applications α-Ethyl-benzeneacetyl Chloride is used in the synthesis of mild and neutral system for selective reduction of organic functional groups. Also used in the preparation of phenothiazine derivatives for the reversible inhibition of human butyrylcholinesterase.
References Sarmah, B. et al.: Tetrahedron, 47, 8587 (1991); Darvesh, S. et al.: Bioorg. Med. Chem., 15, 6367 (2007);

Applications Ethyl-beta,beta,beta-d3-benzene (CAS# 2618-00-0) is a useful isotopically labeled research compound.

Applications 1,3-Propane-d6-diamine, Dihydrochloride is used in the study of trimethylsilylated di and polyamine and their isotopically labelled analogs.
References Smith, R. G., et al.: J. Org. Chem., 43, 2178 (1978)

Applications An intermediate in the synthesis of Metoclopramide.
References Murakami, M., et al.: Chem. Pharm. Bull., 19, 1696 (1971),

Applications D-Methionine-d3 is used for detection D- and L-enantiomers of methionine and [2H3]methionine in plasma by gas chromatography-mass spectrometry of methylated/N-acylated derivatives.
References Hasegawa, H., et al.: J. Chromatogr. B: 823, 203 (2005);

Applications Glyceryl-d5 Tripentadecanoate (CAS# 1219804-57-5) is a useful isotopically labeled research compound.

Applications 2-Aminobenzophenone is a derivative of Benzophenone (B204980), used in the manufacturing of antihistamines, hypnotics, insecticides. 2-Aminobenzophenone was shown to exhibit modulation activity of GABAA receptor-mediated currents in isolated purkinje neurons.
References Kopanitsa, M.V., et al.: Neuropharmacol., 43, 764 (2002); Bringmann, G., et al.: J. Neural. Transmiss. Gen. Sec., 101, 169 (1995);

Applications 1,3-Propanediol-d8 is the labelled version of 1,3-Propanediol (P760320), which is a common organic reagent used in the synthesis of polymers and used in industrial organic chemistry for the synthesis of lubricants, foods, medicines and cosmetics.
References Sun, Y. et al.: Bioproc. Renew. Res. Commod. Bioprod., 289 (2014)

Applications L-Methionine-d3 (S-methyl-d3) Methyl-d3 Sulfonium Chloride (CAS# 362049-54-5) is a useful isotopically labeled research compound.

Applications 1-Methyl-1H-imidazole-4-carboxylic acid

Applications 4-Bromophenol tert-Butyldimethylsilyl Ether (cas# 67963-68-2) is a compound useful in organic synthesis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Stability Hygroscopic
Applications Nalpha-Methylhistamine Dihydrochloride is a H2 receptor agonist.
References Lappin, D., et al.: Clin. Exp. Immunol., 41, 497-504 (1980); Durant, G. J., et al.: J. Med. Chem., 19, 923-928 (1976)

Applications A phenylhydrazone derivative with fungicidal activity.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications N-(3-Methylbutyryl)glycine-2,2-d2 (CAS# 1219795-09-1) is a useful isotopically labeled research compound.

Applications 4-(N-Boc-amino)cyclohexanone is an intermediate in the synthesis of tert-Butyl 1,7-diazaspiro[3.5]nonane-1-carboxylate (B692795). tert-Butyl 1,7-diazaspiro[3.5]nonane-1-carboxylate is a reagent in the preparation of -[4-fluoro-3-(piperazin-1-ylcarbonyl)benzyl]-4,5-dimethylpyridazin-3(2H)-ones as a potent poly(ADP-ribose) polymerase-1 inhibitors active in BRCA deficient cells.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Ferrigno, F., et al.: Bioorg. Med. Chem. Lett., 20, 1100 (2010);

Applications 2-Chloroisonicotinic Acid is a derivative of Isonicotinic Acid (I821760) and is used as a reagent in the synthesis of (phenylmorpholinyl)pyrimidinones as selective and orally active glycogen synthase kinase-3β inhibitors.
References Fukunaga, K., et al.: Bioorg. Med. Chem. Lett., 23, 6933 (2013)

Applications A brominated phenethanol derivative used as a building block in the preparation or bicyclic and tricyclic heterocycles.
References Lemen, G. et al.: Org. Lett., 13, 3218 (2011); Allin, S. et al.: Tetrahedron, 61, 2689 (2005);

Applications 6-methoxy-2,3-dihydro-1H-indene-1-carboxylic acid (cas# 62956-62-1) is a useful research chemical.

Applications N1,N2-Bis(4-hydroxy-2,6-dimethylphenyl)ethanediamide is an intermediate used in the synthesis of 1-Naphthol-d7 (d6 Major) (N367993), which is the isotope labelled analog of 1-Naphthol (N367990), a compound commonly used in the manufacturing of dyes, intermediates, synthetic perfumes.

Applications n-Nonyl-6,6,7,7-d4 Alcohol (CAS# 33975-46-1) is a useful isotopically labeled research compound.

Applications 1-Bromododecane-d25 (CAS# 204259-66-5) is a useful isotopically labeled research compound.

Applications 1-Bromododecane-12,12,12-d3 (CAS# 204259-68-7) is a useful isotopically labeled research compound.

Applications Glyceryl Tri(hexadecanoate-d31) (CAS# 241157-04-0) is a useful isotopically labeled research compound.

Applications Butyryl-d7-L-carnitine HCl is a useful isotopically labeled compound of (R)-Butyryl Carnitine Chloride (B802700)

Stability Volatile
Applications Cyclopropanecarboxaldehyde is a reagent in the preparation of N-alkylphenylalaninamides of pyridinylphenyl- and oxobipyridinylamines as human GPR 142 agonists for potential use as anti-diabetic agents and the cytochrome P 450 inhibition.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Lizarzaburu, M., et al.: Bioorg. Med. Chem. Lett, 22, 5942 (2012)

Applications Photoreduction of N-methylphthalimide (NMP) with 2,3-dimethyl-2-butene h and the selective electroreduction of N-methylphthalimide to 3-hydroxy-2-methyl-isoindolin-1-one have been studied.
References Mazzocchi, P., et al.: J. Am. Chem. Soc., 106, 7567 (1984); Villagran, C., et al.: Ultrasonics Sonochemistry, 12, 423 (2005)

Applications 4-Piperidinemethanol, is a building block that can be used for the synthesis of selective inhibitors of sphingosine kinase 1 (SK1), that may serve as therapeutic agents for proliferative diseases, including hypertension.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Baek, D., et al.: Chem.l Commun., 49, 2136 (2013);

Applications 6-Bromopiperonal is a disubstituted 1,3-benzodioxole that displayed synergistic activity with carbaryl on houseflies. 6-Bromopiperonal is used as an intermediate in the preparation of GPR30-selective agonist G-1.
References Wilkinson, C.F. et al.: J. Agric. Food Chem., 15, 139 (1967): Hewlett, P.S. et al.: J. Sci. Food Agric., 18, 279 (1967); Burai, R. et al.: Org. Biomol. Chem., 8, 2252 (2010);

Applications 6-Bromopicolinic acid

Applications (2-Bromoethoxy)-tert-butyldimethylsilane can be used in N-alkylation with 5-piperazin-1-yl-1H-indole to synthesize 5-(4-(2-((tert-butyldimethylsilyl)oxy)ethyl)piperazin-1-yl)-1H-indole.
References Johnson, M., et al.: J. Med. Chem., 55, 5828 (2012)

Applications 2-Ethyl-d5-toluene is a useful isotopically labeled compound of 2-Ethyl Toluene (E926634)

Applications epsilon-Caprolactone-3,3,4,4,5,5-d6 (CAS# 1219802-08-0) is a useful isotopically labeled research compound.

Applications Diethyl-d10-amine HBr (CAS# 1219803-53-8) is a useful isotopically labeled research compound.

Applications 3-Methylbenzamide (cas# 618-47-3) is a useful research chemical.

Applications methyl 5-oxo-5-phenylpentanoate (cas# 1501-04-8) is a useful research chemical.

Applications An intermediate of Rosuvastatin.

Applications 4-(1-Piperazinyl)-1H-indole Dihydrochloride (cas# 84807-09-0) is a compound useful in organic synthesis.

Applications Ethyl-alpha,alpha-d2-benzene (CAS# 1861-01-4) is a useful isotopically labeled research compound.

Applications An intermediate in the preparation of pharmaceutically active Cyproheptadines.
References Thompson, W., et al.: J. Med. Chem., 33, 789 (1990),

Applications 3-methyl-2-oxo-2,3-dihydrobenzo[d]oxazol-5-ylboronic acid, pinacol ester (cas# 1220696-32-1) is a useful research chemical.

Applications Misonidazole can be used as a potential hypoxic cancer cell radiosensitizer and DNA binding and nicking agent. The metabolites of misonidazole can themselves be cytotoxic or they can increase the chemosensitivity and radiosensitivity of the target cells
References Bonnet, M., et al.: Bioorg. Med. Chem., 22, 2123 (2014); Edwards, D.I.: Comprehensive Med. Chem., 2, 725 (1990); Murata, R., et al.: Radiother. Oncol., 87, 331 (2008); Brown, J.M. The mechanisms of cytotoxicity and chemosensitization by misonidazole and other nitroimidazoles. Int.J.Radiat.Oncol.Biol.Phys. 8(3-4), 675-682 (1982).

Applications 3-Piperidinesulfonic Acid is an isomer of piperidine-4-sulfonic acid, a new specific GABA agonist.
References Krogsgaard-Larsen, P., et al.: J. Neurochem., 34, 756 (1980)

Applications Ethyl-d5-benzene (CAS# 38729-11-2) is a useful isotopically labeled research compound.

Applications Cyclopropane-1-d1-carboxylic Acid (CAS# 19136-94-8) is a useful isotopically labeled research compound.

Applications Hexadecanoic Acid-1,2-13C2 (CAS# 86683-25-2) is a useful isotopically labeled research compound.

Applications Hexadecanoic-7,7,8,8-d4 Acid (CAS# 75736-49-1) is a useful isotopically labeled research compound.

Applications 4-Ethylbenzoic acid

Applications 2-(1H-pyrazol-4-yl)aniline (cas# 1342757-33-8) is a useful research chemical.

Applications N-Suberylglycine-2,2-d2 (CAS# 1219799-02-6) is a useful isotopically labeled research compound.

Applications Labelled analogue of 2-Bromopropane, a short chain alkyl halide used in organic synthesis primarily as an alkylating agent for introducing the isopropyl functional groups.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Mayants, A.G. et al.: Zhur. Org. Khim., 25, 419 (1989); Miller, B. et al.: J. Org Chem., 30, 3895 (1965);