Building Blocks

<p>Applications Diethyl Phenylmalonate is a reagent used in the synthesis of antituberculosis agents.<br>References Ng, P. S., et al.: J. Med. Chem., 106, 144-156 (2015)<br></p>

<p>Applications 2,2-Difluoropropionic acid (cas# 373-96-6) is a useful research chemical.<br></p>

<p>Applications Diisopropyl Malonate is a disinfection byproduct of Isoprothiolane (I874300); a dithiolane pesticide commonly used in agriculture as a fungicide to control planthoppers and blast disease in rice plants.<br>References Chin, K.M.: Malay. Agric. J., 50, 221 (1975); Ikeda, Y. et al.: Biosci. Biotech. Biochem., 57, 288 (1993); Nakamura, H.: Rev. Plant Prot. Res., 10, 1 (1977); Reddy, A.P.K. et al.: Pesticide, 22, 21 (1988); Jinno, H., et al.: Arch. Toxicol., 71, 550 (1997)<br></p>

<p>Applications 1,1-dimethylguanidine Sulfate (cas# 598-65-2) is a useful research chemical.<br></p>

<p>Applications 3-(Dimethylamino)-1,2-propanediol is a reagent in the synthesis of 1,2-Dioleoyl-3-trimethylammonium-propane, Chloride (D484450).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications 4,5-Dimethyl-3-isoxazolamine is an isoxazole derivative used in the preparation of a varitey of biologically active compounds such as selective ETA receptor antagonists.<br>References Murugesan, N. et al.: J. Med. Chem., 46, 125 (2003);<br></p>

<p>Applications 1,2-Dimethylisothiourea-HI (cas# 41306-45-0) is a useful research chemical.<br></p>

<p>Applications Diphenyl Chlorophosphonate, is a building block used for the synthesis of various chemical compounds. It can be used for the synthesis of phosphate esters of polyhedral hydroxyboranes, showing enhanced tumor uptake.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bechtold, R., et al.: J. Med. Chem., 18, 371 (1975);<br></p>

<p>Applications N,N-Dimethylmethyleneiminium Iodide (cas# 33797-51-2) is a useful research chemical.<br></p>

<p>Applications Ethyl 2-Aminothiophene-3-carboxylate (cas# 31891-06-2) is a compound useful in organic synthesis.<br></p>

<p>Applications Ethyl 2-bromobutyrate is used in synthetic chemistry as a polymerization initiator. Ethyl 2-bromobutyrate is also used as a reagent to synthesize Efaroxan, an imidazoline α 2-antagonist that stimulated insulin secretion in rat pancreatic cells.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ball, A., et al.: Pharm. Res., 42, 575 (2000); Bibiao. J. et al.: Eur. Polym. J., 42, 179 (2006); Chan, S. &amp; Morgan, N.: Eur. J. Pharm., 176, 97 (1990); Xu, W., et al.: Eur. Polym. J., 39, 1349 (2003)<br></p>

<p>Applications Ethyl Cyano(ethoxymethylene)acetate is an intermediate in the synthesis of anti-inflammatory agents with gastroprotective effect in rats.<br>References Karoui, A., et al.: Med. Chem. Res., 23, 1591 (2014);<br></p>

<p>Applications Used as a reactant or reagent in preparation of N-alkyl carbamates.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lazewska, D. et al.: BioMed. Chem. Let., 19, 6682 (2009);<br></p>

<p>3-Mercapto-2-pyridinecarboxylic acid hydrochloride (3MP) is a small molecule that is a phosphoenolpyruvate carboxykinase inhibitor. The inhibition of this enzyme leads to an accumulation of 3-phosphoglyceric acid and inhibits the conversion of pyruvate to acetyl CoA, which results in the accumulation of reactive oxygen species. 3MP has been shown to inhibit the activity of mitochondrial phosphoenolpyruvate carboxykinase (PEPCK) in porcine hepatocytes, leading to decreased triglycerides and increased glucose uptake. It also inhibits PEPCK activity in vitro in cultured human cells, leading to increased HSP70 levels and exacerbated oxidative stress.</p>

<p>4'-Iodoacetophenone is a catalyst in organic synthesis. It is a cross-coupling agent that is used to catalyze reactions of alkyl halides with organometallic compounds. The reaction mechanism is the same as for other cross-coupling reactions and involves the formation of a palladium complex. 4'-Iodoacetophenone has been shown to be effective in asymmetric synthesis, where it can be used as a homogeneous catalyst. This compound has also been shown to be an efficient methylating agent and can be used in the methylation of various functional groups, such as amines, nitro groups, and phenols.</p>

<p>6-Bromo-2-(4-bromophenyl)-indole is a fine chemical with CAS No. 28718-96-9 that can be used as a versatile building block for the synthesis of complex compounds, useful scaffold for research chemicals, and reaction component for speciality chemicals. This compound has high quality and is a reagent in the synthesis of other compounds.</p>

<p>(S)-(+)-3-Methyl-1-pentanol is a branched-chain, β-unsaturated aldehyde that is produced by the elimination of two molecules of water from (R)-(+)-3-methylbutanal. It is an organocatalytic substrate for the family of enzymes that catalyze the first step in the biosynthetic pathway to abiotic long-chain alcohols. The product is an intermediate in the biosynthesis of escherichia coli and other bacteria. The enzyme involved in this reaction is initially activated by acetate and then inhibited by NADH. In nature, this compound can be found as a natural product or as a metabolic intermediate.</p>