Building Blocks

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Octane-1-sulfonamide (OSA) is a glycol ether that is used as a reagent for biological samples. It reacts with the hydroxyl group on proteins, which causes the compounds to become more hydrophobic and interact with each other. The OSAs are also reactive with fatty acids, which leads to cross-linking of cell membranes. This interaction may be related to the low light activity of OSA. Octane-1-sulfonamide can also bind cationic polymers, which may be useful in ophthalmic drugs.</p>

<p>Versatile small molecule scaffold</p>

<p>Methyl 2,6-dichloropyridine-3-carboxylate is a carboxylic acid that can be synthesized by reacting 2,6-dichloropyridine with an acetyl chloride. It has been used in the synthesis of dopamine D2 receptor antagonists. The sulfoxide group in this compound may undergo alkaline hydrolysis to yield an anion and a nucleophilic adduct. This carboxylic acid also reacts with triethylamine to form esters. In addition, methyl 2,6-dichloropyridine-3-carboxylate is regioselective for the alpha position when it reacts with methyltetrahydrofuran.</p>

<p>6-Chloro-2-methoxynicotinic acid is a ketone that reacts with chlorine in the presence of light to form chlorinated products. It is a versatile intermediate for the synthesis of various compounds. 6-Chloro-2-methoxynicotinic acid is used in the synthesis of naphthacene, which is a precursor to dyes and pharmaceuticals. The reactivity of this compound depends on substituents located at the 2 position. Substituents cause sterically hindering effects and lead to different geometries and reactivities, such as attack by chlorine or substitution by hydrogen.</p>

<p>2-Methoxy-4,6-dimethylnicotinonitrile is a photoreactive compound that reacts with UV light to produce an adduct. The 1-cyanonaphthalene group in 2-methoxy-4,6-dimethylnicotinonitrile undergoes a photochemical reaction to form an adduct with the benzene ring. It is postulated that the dimer and x-ray structural analysis of 2-methoxy-4,6-dimethylnicotinonitrile are stable and pyridine can be used as a solvent.</p>

<p>2-Amino-4-(aminooxy)butanoic acid dihydrochloride is a cyclization product of the antibiotic cycloserine. It has been synthesised from 2-amino-4-oxobutanoic acid by the addition of hydrochloric acid and then heated to reflux for 20 hours. The purity of this product is &gt;98%.<br>2-Amino-4-(aminooxy)butanoic acid dihydrochloride has been shown to be a homologue of canaline, which is an antibiotic used in the treatment of tuberculosis. This compound also has antibacterial activity, although it is less potent than cycloserine.</p>

<p>(2E,4E)-Hepta-2,4-dienoic acid is an organic compound that belongs to the group of quinoline derivatives. It is a colorless liquid at room temperature and is soluble in organic solvents. This compound can be used as a dehydrohalogenating agent in the synthesis of mappicine and camptothecin derivatives. (2E,4E)-Hepta-2,4-dienoic acid can also react with ketocarboxylic acids to form carotenoid compounds. The chemical formula for this molecule is C8H10O3.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Adriamycin, also known as 1-Phenylpyrrolidin-3-ol, is a chemotherapy drug that is used to treat various types of cancer. It is classified as a chemotherapeutic agent and is an inhibitor of DNA synthesis. Adriamycin has been shown to be active against human fibrosarcoma, leukemia HL-60, and promyelocytic leukemia cells in vitro. In addition, it has been found to be effective against resistant T-cell leukemia and lymphocytic leukemia cells. This drug inhibits the proliferation of tumor cells by binding to DNA and preventing RNA synthesis or protein synthesis in the cell's ribosomes. Adriamycin also binds to leucovorin, which is a form of folic acid that prevents its toxicity in the body.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>2-Bromo-1-(1-pyrrolidinyl)-1-ethanone (2BP) is an acetylcholine analog that inhibits the cck-a, or acetylcholine receptor. It is a prodrug that is converted by thiourea into the active 2BP analog. 2BP has been shown to inhibit the binding of both nicotinic and muscarinic acetylcholine receptors in rat brain tissue. The affinity of this drug for the human cck-a receptor was found to be approximately 10 times less than for rat cck-a receptor. This indicates that 2BP may not be effective in humans because it does not bind well to the human receptor.</p>

<p>2-Amino-3-(4-hydroxyphenyl)propanoic acid is a proteinogenic amino acid that is essential for humans and other animals. It can be synthesized by the human body in sufficient quantities from the amino acid phenylalanine, so it is not considered an essential dietary component. This amino acid can also be found in dairy products, eggs, soybeans, and peanuts. 2-Amino-3-(4-hydroxyphenyl)propanoic acid (2S)-2-(Carbamoylamino)-3-(4-hydroxyphenyl)propanoic acid) has been shown to reduce insulin resistance in diabetic rats. In addition, it has been shown to increase the uptake of glucose into muscle cells. 2S)-2-(Carbamoylamino)-3-(4-hydroxyphenyl)propanoic acid is formed as a result of carbamylation of lys</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-Aminonaphthalen-2-ol is a synthetic reagent that is used in organic chemistry. It can be prepared from the reaction of chlorides and benzofurans, which are synthesized from an electrophilic aromatic substitution reaction with sodium hydroxide. The efficiency of this process can be enhanced by using imidazole as a solvent or as a catalyst for the reaction. 4-Aminonaphthalen-2-ol is also used in the synthesis of imidazole derivatives, such as 2-(4-aminophenyl)imidazo[1,2-a]pyridine.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>4-Propoxyphenyl Methanol is a nonnutritive sweetener that is approximately 200 times sweeter than sucrose. It is used as an additive to sugar substitutes, tabletop sweeteners, and soft drinks. 4-Propoxyphenyl Methanol is not metabolized by the body and has no known health risks.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>1H-Pyrrole-3-carbothioamide is a non-nucleoside inhibitor of HIV reverse transcriptase. It is hypothesized to work by binding to the active site of the enzyme and inhibiting the formation of covalent bonds between the enzyme and its substrate, which prevents DNA synthesis. The mechanism for inhibition has been studied using molecular dynamics simulations and kinetic studies. 1H-Pyrrole-3-carbothioamide inhibits viral replication in vitro by inhibiting the function of HIV reverse transcriptase. This compound also shows activity against other RNA viruses such as Hepatitis C virus, Influenza A virus, and West Nile Virus.</p>

<p>Versatile small molecule scaffold</p>

<p>Versatile small molecule scaffold</p>

<p>5H,6H-[1,2,4]Triazolo[4,3-c]pyrimidin-5-one is a potent antitumor agent that is structurally similar to the cytotoxic agents mcf-7 and doxorubicin. It has been synthesized by the reaction of an enaminone with diazonium salt. The synthesis of 5H,6H-[1,2,4]Triazolo[4,3-c]pyrimidin-5-one has been carried out using a number of techniques including halide exchange reactions with amines and enaminones. This compound has been shown to be active against breast cancer cells in culture and induces apoptosis by interfering with DNA replication.</p>

<p>Versatile small molecule scaffold</p>