Estándares farmacéuticos

Synthetic analog of dolastatin 10; cytotoxic; inhibits tubulin polymerization

Applications 3-Hydroxy Carbamazepine tert-Butyldimethylsilyl Ether is an protected metabolite of Carbamazepine (C175840).
References Park, B., et al.: Biochem. Pharmacol., 36, 581 (1987), Yamazaki, H., et al.: Drug Metab. Dispos., 27, 1260 (1999), Dieckhaus, C., et al.: Chem. Res. Toxicol., 14, 958 (2001),

Applications (2S,5R)-3-(Azidomethyl)-3-methyl-7-oxo-4,4-dioxide-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid Diphenylmethyl Ester is an intermediate in the synthesis of Tazobactam Sodium Salt-13C2,15N1 (T010102), which is the labelled analogue of Tazobactam Sodium Salt (T010100), which is a β-Lactamase inhibitor, used with β-lactam antibiotics to enhance their effect.
References Gould, I.M., et al.: Drugs Exp. Clin. Res., 17, 187 (1991), Roland, R.K., et al.: J. Infect. Dis., 4, 226 (2000), Bonomo, R.A., et al.: Biochim. Biophys. Acta, 1547, 196 (2001),

Applications 2,3,7,8-Tetrachloro-[1,4]dioxino[2,3-b:5,6-b']dipyridine is used in analytical studies for the presence and formation of dioxin-like compounds in heat-treated chlorpyrifos herbicide, a potential precursor of pyridine analog of 2,3,7,8-Tetrachloro-p-dioxin (T291370).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Sakiyaama, T., et al.: Organohalogen Compounds, 73, 146 (2011);

Applications N-Nitro-S-methylisothiourea-13C is an intermediate used in the synthesis of Clothianidin-d3, 13C1 (C588502), which is the isotope labelled analog of Clothianidin. Clothianidin is a neonicotinoid insecticide for use in food crops.
References Kamel, A., et al.: J. Agric. Food Chem., 58, 5926 (2010), Lynd, L., et al.: Energy Environ. Sci., 3, 1150 (2010), Cresswell, J., et al.: Ecotoxicology, 20, 149 (2011),

Applications 3,5-Di(tert-butyldimethylsilyl) Rosuvastatin Acyl-β-D-glucuronide Allyl Ester is a compound useful in organic synthesis.

Applications Used in the preparation of quinolones, benzoxazolones, and benzoxazinones as β agonists for the treatment of respiratory diseases

Applications 2-(Ethoxymethyl)-α,α-dimethyl-1H-imidazo[4,5-c]quinoline-1-ethanol-d5 is an intermediate in synthesizing Resiquimod-d5 (R144682), an isotope labelled Resiquimod (R144680) which is an imidazoquinoline derivative that acts as an immune response modifier. Resiquimod shows antitumor and antiviral activity and is used in the treatment of skin lesions such as herpes simplex virus. Resiquimod is a toll-like receptor 9 (TLR7) agonist.
References Wu, J.J. et al.: Antivir. Res., 64, 79 (2004); Fife, K.H. et al.: Antimicrob. Agents Chemother., 52, 477 (2008); Szeimies, R.M. et al.: Brit. J. Dermatol., 159, 205 (2008)

Applications 2-[(1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl)acetyl]-butanedioic-2-13C Acid Diethyl Ester is an intermediate in the synthesis of 5-Aminolevulinic Acid-3-13C Hydrochloride which is a naturally occurring amino acid; precursor of tetrapyrroles in the biosynthesis of chlorophyll and heme. Antineoplastic (photosensitizer).
References Sisler, E.C., et al.: Physiol. Plant., 16, 315 (1963), Herdeis, C., et al.: Arch. Pharm., 317, 304 (1984), Peng, Q., et al.: Cancer, 79, 2282(1997),

Applications (2E,6Z,8E)-2,6,8-Decatrienoic Acid Methyl Ester is an spilanthol (S681850) related amide found from Acmella ciliata.
References Martin, R., et al.: Phytochem., 23, 1781 (1984);

Applications 2-Hydroxy-5-benzyloxyacetophenone (cas# 30992-63-3) is a compound useful in organic synthesis.

Applications 2-Acetamido-3-(benzyloxy)benzoic Acid Methyl Ester is an intermediate in the synthesis of metabolites of Bentazon (B120580), a selective post-emergence herbicide.

Applications 6,7,8-Trifluoro-4-oxo-1-(1-oxopropan-2-yl)-1,4-dihydroquinoline-3-carboxylic Acid Ethyl Ester is an intermediate in the synthesis of Marbofloxacin (M197000), a fluorinated quinolone antibacterial agent.
References Gruet, P., et al.: Vet. Rec., 140, 199 (1977), Lefebvre, H.P., et al.: J. Vet. Pharmacol. Ther., 21, 453 (1998),

Applications Tetrabromophthalic Anhydride-13C6 is an intermediate in synthesizing 2,3,4,5-Tetrabromobenzoic Acid-13C6 (T291142). It is an isotope labelled analog of 2,3,4,5-Tetrabromobenzoic Acid. 2,3,4,5-Tetrabromobenzoic Acid is an in vitro metabolite of the flame retardant 2-Ethylhexyl 2,3,4,5-Tetrabromobenzoate (E918780) in human and rat tissues.
References Roberts, S.C., et al.: Chem. Res. Toxicol., 25, 1435 (2012); Gouteux, B., et al.: Environ. Sci. Technol., 42, 9039 (2008); Lee, E., et al.: J. Toxicol. Sci., 2010, 35, 535 (2010); Arp, H., et al.: J. Environ. Monit., 13, 505 (2011)

Applications (S)-2-(Dimethoxymethyl)-1-pyrrolidinecarboxylic Acid 1,1-Dimethylethyl Ester is an intermediate in synthesizing Tilivalline (T440350), which is a metabolite from Klebsiella oxytoca. Tilivalline, is shown to be cytotoxin, and the key event causing Antibiotic-Associated Hemorrhagic Colitis.
References Mori, Sh., et al.: Tetrahedron, 47, No.27, 5051 (1991); Nagasaka, T., et al.: Tetrahedron Lett., 14, 1871 (1989);

Applications 3-​Oxime Estra-​4,​9,​11-​triene-​3,​17-​dione is an intermediate in synthesizing Altrenogest 19,19,20,21,21-d5 (A575757), a labelled Altrenogest (A575755) which is a synthetic progestational agent used in veterinary medicine for the control of estrus in mares.
References Machnik M. et al.: J. Vet. Phamacol. Therap., 30, 86 (2007); Goncalves dos Santos, J.M. et al.: Anim. Reprod. Sci., 84, 407 (2004)

Applications 3-Iodopropylene-1-naphthalene Methyl Amine (cas# 1076198-32-7) is a compound useful in organic synthesis.

Applications 3-Methylphosphinicopropionic Acid Diethyl Ester is a derivative of 3-Methylphosphinicopropionic Acid Sodium Salt (M326160), a metabolite of Glufosinate (G596950). 3-Methylphosphinicopropionic Acid Diethyl Ester is used in the preparation of the naturally occurring amino acid, Phosphinothricin.
References Zeiss, H.: J. Org. Chem., 56, 1783 (1991)

Applications 2-Amino-4,6-dihydroxy-5-nitropyrimidine (cas# 80466-56-4) is a compound useful in organic synthesis.

Applications 4-S-Methylisothiourea Dipicolinic Acid Dimethyl Ester Hydrobromide is a compound useful in organic synthesis.

Applications A coordination compound for treatment of cervix cancer.
References Jiang, M., et al.: Methods Mol. Biol., 292, 401 (2005), Fujii, T., et al.: Int. J. Oncol., 29, 541 (2006), Niu, X., et al.: Int. J. Gynecol. Cancer, 16, 743 (2006),

Applications Prochlorazium N3-Methyl Iodide is an intermediate in synthesizing BTS 44596 (B689355), which is a metabolite of Prochloraz (P755280), an effective fungicide against cereal powdery mildew.
References Riviere, J.-L., et al.: Pestic. Sci., 15, 317 (1984); Debrauwer, L., et al.: J. Agric. Food Chem., 49, 3821 (2001)

Applications 1,4-Naphthoquinone is a reagent used in pharmaceutical synthesis of novel drug candidates. Used in preparation of 1,4-napthalenedione motif with phosphonic acid moiety in hepatocellular carcinoma HepG2 cells
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Dlugosz, A. et al.: Acta. Biochim. Polo., 64, 41 (2017);

Applications Used as an animal glue liquifier, silver tarnish remover, fixing agents, manufactured resins and vulcanization accelerators. It is a known carcinogen, also causes bone marrow depression and goiters.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Butola, J., et al.: J. Plant Biol., 35, 75 (2008), Roux-Dalvai, F., et al.: Mol. Cell. Proteom., 7, 2254 (2008), Ansari, F., et al.: J. Enz. Inhibit. Med. Chem., 24, 151 (2009),

Applications 3-Aminobenzoic-d4 Acid (A591492) derivative. It increases attractiveness when combines with sex pheromones.
References Maekawa, M. et al.: Appl. Entomol. Zool., 34, 9 (1999)

Applications 4-Nitrophenyl Phosphorodichloridate is used as a reagent in the synthesis of dihydrobenzodioxaphosphocine oxide derivatives which have antioxidant activity.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Siva Prasad, S., et al.: J. Heterocyclic Chem., no vol., no pp. (2016, ahead of print)

Applications Dichloroacetic Acid Methyl Ester is used in the preparation of telechelics and block copolymers through living radical polymerization.
References Keul, H., et. al.: Macromol. S., 19, 1 (1971)

Applications 5-Chloro-2-methoxy-1,3-benzenedicarboxylic Acid is an intermediate in the synthesis of Ochratoxin A (O148490). Ochratoxins are toxic metabolites from Aspergillus ochraceus. Also they are environmental and food contaminants.
References Belli, N., et al.: Int. J. Food Microb., 96, 19 ( 2004); Pardo, E., et al.: Food Microb., 23, 35 (2006)

Applications (-)-Galanthaminyl (-)-Camphanate (cas# 1025881-27-9) is a compound useful in organic synthesis.

Applications α-(Dibutylamino)-4-methoxy-benzeneacetic Acid is an intermediate in the synthesis of Ambucetamide (A575935). Ambucetamide is an antispasmodic found to be particularly effective for the relief of menstrual pain.
References Janssen, P., et al.: J. Am. Chem. Soc., 76, 6192 (1954); Pickles, V., et al.: 15, 128 (1960)

Applications 9,10-Dichloro-2,6-dimethylanthracene (cas# 887354-46-3) is a compound useful in organic synthesis.

Applications 2,​3,​4-​Triacetate 1-​(2,​2,​2-​Trichloroethanimidat​e) 6-​O-​(2,​3,​4,​6-​Tetra-​O-​acetyl-​β-​D-​glucopyranosyl)​-β-​D-​glucopyranose is an intermediate in the synthesis of Guaiacol-beta-D-gentiobioside (G245570), which is a Guaiacol Conjugate, that has shown to present in fermentation of grapes that had been exposed to bushfire smoke and can potentially yield unpalatable, smoke-affected wine.
References Hayasaka, Y.m et al.: J. Arg. Food Chem., Vol. 58, Issue 4, P: 2076; 2081 (2010);

Applications 7-(Dimethylamino)-4-methylcoumarin (cas# 87-01-4) is a useful research chemical.

Applications Acetophenone-13C8 is an intermediate in synthesizing Mandelic Acid-13C8 (M162523). It is a C13 labelled Mandelic Acid which is used as an antiseptic (urinary). It is also used as a short-term exposure biomarker in urine from styrene exposed workers.
References Pessela, B., et al.: Enzyme Microb. Technol., 40, 310 (2007); Carrasco-Lopez, C., et al.: J. Biol. Chem., 284, 4365 (2009); Fustinoni, S., et al.: Toxicol. Lett., 192, 40 (2010)

Applications 4-Fluoro-1-naphthoic acid (cas# 573-03-5) is a useful research chemical.

Applications 2-Bromo-5-nitropyridine (cas# 4487-59-6) is a compound useful in organic synthesis.

Applications A bactericidal and fungicidal.
References Schoppelrei, J., et al.: J. Phys. Chem., 100, 14343 (1996), Kolb, H., et al.: Drug Discovery Today, 8, 1128 (2003),

Applications α-Ionol derivative.

Impurity Vonoprazan Impurity 31
Applications 2'-Fluoroacetophenone (Vonoprazan Impurity 31)

Applications 2'-Bromoacetanilide is used as a reagent in the preparation of furan-2-ylmethylene thiazolidinediones as novel, potent, and selective inhibitors of phosphoinositide 3-kinase γ.
References Pomel, V., et al.: J. Med. Chem., 49, 3857 (2006);

Applications Antifungal activity, particularly toward Candida albicans and Candida parapsilosis.
References Upadhayaya, R., et al.: Eur. J. Med. Chem., 39, 579 (2004), Sheng, C., et al.: J. Med. Chem., 49, 2512 (2006)

Applications An intermediate for the synthesis of the metabolite of Flurbiprofen, an anti-inflammatory used as an analgesic.

Applications Phenobarbital 1,3-Diethyl Butyrate is a byproduct in the synthesis of Phenobarbital 1-Butyric Acid (P316750) which is a Phenobarbital derivative.
References Deleide, G., et al.: Clin. Chimica Acta, 99, 195 (1979),

Impurity Candesartan Impurity
Applications A byproduct formed during the synthesis of labelled Candesartan.
References Kubo, K., et al.: J. Med. Chem., 36, 2182 (1993)

Applications (17β)​-17-​Hydroxy-estra-​4,​9,​11-​trien-​3-​one Oxime is an intermediate in synthesizing Altrenogest 19,19,20,21,21-d5 (A575757), a labelled Altrenogest (A575755) which is a synthetic progestational agent used in veterinary medicine for the control of estrus in mares.
References Machnik M. et al.: J. Vet. Phamacol. Therap., 30, 86 (2007); Goncalves dos Santos, J.M. et al.: Anim. Reprod. Sci., 84, 407 (2004)

Applications Isomer of (3R)-3-Hydroxy Quinine

Applications 4-Fluoro-1-naphthalenol (cas# 315-53-7) is a compound useful in organic synthesis.

Applications 1,3-Boc-9-Methyl-(+)-Biotin Methyl Ester is an intermediate in the synthesis of 9-Methyl Biotin (mixture of diastereomers) (M294075), which is an impurity of Biotin (B389040). Biotin EP Impurity D.
References Trotter, J., et al.: Biochemistry, 5, 713 (1966), Suurkuusk, J., et al.: Eur. J.Biochem., 28, 438 (1972),

Applications 2,4-Dibromo Deuteroporphyrin IX Dimethyl Ester is an intermediate for the synthesis of Protoporphyrin IX Dimethyl Ester-d6 (P839127), which is the labelled version of Protoporphyrin IX P(P838900). Protoporphyrin IX (PPIX) is ubiquitously present in all living cells in small amounts as a precursor of heme and PPIX-based strategies have been used for cancer diagnosis and treatment. It can be used in biological study for role of protoporphyrin IX in skin photosensitivity, biliary stones, hepatobiliary damage, liver failure and cancer diagnosis and treatment in human.
References Sachar, M., et al.: J. Pharmacol. Exp. Ther., 356, 267-275 (2016)

Applications (Z)-3-Methylpent-2-en-4-yn-1-ol is used as a reagent in organic synthesis of many compounds including that of prolycopene which is a tangerine-colored tetra-Z-isomer of lycopene that is found in fruits of the tangerine tomato. Z)-3-Methylpent-2-en-4-yn-1-ol is also used in the synthesis of Leucosceptroids A and B which have potent antifungal properties.
References Pattenden, G., et al.: Tetrahedron Lett., 28, 5751 (1987); Guo, S., et al.: Angew. Chem. Int. Edit., 54, 1298 (2015);

Applications Nintedanib Demethyl-O-glucuronic Acid-d3 is an isotopic analog of Nintedanib Demethyl-O-glucuronic Acid (N478295), a metabolite of the drug Nintedanib (N478290).
References Sun, L., et al.: J. Med. Chem., 41, 2588 (1998); Xie, H., et al.: J. Med. Chem., 50, 4898 (2007); Hilberg, F., et al.: Cancer Res., 68, 4774 (2008); Roth, G., et al.: J. Med. Chem., 58, 1053 (2015)

Applications N-​(4-​Cyanobutyl)​-​N-​(phenylmethoxy)​-​carbamic Acid 1,​1-​Dimethylethyl Ester is an intermediate in synthesizing Deferoxamine-d7 TFA Salt (D228982), a labelled Deferoxamine Mesylate (D228980), which is an iron chelating agent used in therapy for patients with sickle cell diseases and iron overload. Studies suggest that it can exert potential antioxidant neuroprotective effects in stroke patients.
References Inati, A. et al.: Am. J. Hematol., 85, 782 (2010); Selim, M.: Translat. Stroke Res., 1, 35 (2010); Cappellini, M.D. et al.: Hemoblobin, 33, 258 (2009)

Applications 4-Hydroxy Estrone 3-O-β-D-Glucuronide Triacetate Methy Ester is an intermediate in the synthesis of 4-Hydroxyestradiol 4-O-β-D-Glucuronide Sodium Salt, which is a glucuronide derivative of 4-Hydroxy-17β-estradiol (H941895); a metabolite of Estradiol (E888000) which is the major estrogen secreted by the premenopausal ovary.
References Bucala, R., et al.: J. Clin. Endocrinol. Metab., 60, 841 (1985); Telang, N., et al.: Anticancer Res., et al.: 11, 1021 (1991); Seeger, H., et al.: Med. Sci. Res., 26, 481 (1998); Bolton, J., et al.: Chem. Res. Toxicol., 13, 135 (2000); Salole, E.G., et al.: Anal. Profiles Drug Subs., 15, 283 (1986); Lievertz, R.W., et al.: Am. J. Obstet. Gynecol., 156, 1289 (1987)

Applications (2R,4S)-2-[(2S,5S)-5-(4-Hydroxyphenyl)-3,6-dioxo-2-piperazinyl]-5,5-dimethyl-4-thiazolidinecarboxylic Acid is an impurity in the synthesis of N-(Penicillan-6-yl) Open Ring Amoxicillinamide Disodium Salt , whch is an impurity of Amoxicillin (A634235); a semi-synthetic antibiotic related to Penicillin (P233500). Antibacterial.
References Brogden, R.N., et al.: Drugs, 18, 169 (1979); Bird, A.E., et al.: Anal. Profiles Drug Subs. Excip., 23, 1 (1994)

Applications An intermediate in the synthesis of the Daspone metabolite.

Applications N-(1-Naphthyl-d7-methyl)methylamine (cas# 1189686-07-4) is a compound useful in organic synthesis.

Applications 5-Bromo-2',3',5'-tri-O-acetyluridine (cas# 105659-32-3) is a compound useful in organic synthesis.

Applications 1-ETHYLNAPHTHALENE (cas# 1127-76-0) is a useful research chemical.

Applications Hippurate analog. Inhibitor of peptidylglycine α-hydroxylating monooxygenase (PHM). Pesticide.
References Merkler, D. et al. Bioorgan. Med. Chem. 16, 10061 (2008)

Applications Intermediate in the synthesis of polycyclic aromatic systems.

Applications α-(Phenylmethylene)-1-naphthaleneacetic Acid is an intermediate in the synthesis of chrysene based polycyclic aromatic ketones found in environmental gas samples of wood and coal combustion gasses, municipal incineration waste gases, diesel exhaust, Al plant workplace and urban ambient air.
References Dai, W., et al.: Org. Prep. Proc. Int., 29, 347 (1997);

Stability Readily Polymerizes
Applications A precursor of polynuclear aromatic hydrocarbons in tobacco smoke.

Applications Penicillanic Acid Sodium Salt-d2 is an intermediate in the synthesis of Tazobactam-d4 which is the labeled analog of Tazobactam (T010095), a β-Lactamase inhibitor, used with β-lactam antibiotics to enhance their effect.
References Gould, I.M., et al.: Drugs Exp. Clin. Res., 17, 187 (1991); Roland, R.K., et al.: J. Infect. Dis., 4, 226 (2000); Bonomo, R.A., et al.: Biochim. Biophys. Acta, 1547, 196 (2001)

Stability Hygroscopic
Applications Dihydroxyacetone Phosphate Lithium Salt, is a metabolic intermediate involved in involved in a wide variety of metabolic pathways including glycolysis and lipid biosynthesis. In plants, Dihydroxyacetone phosphate is involved with the synthesis of vitamin B6.
References Jun Ogawa et. al.: et al.: Bioscience, biotechnology, and biochemistry, 67(4), undefined (2003-6-6); John P Richard, Biochemistry, 51(13), undefined (2012-3-14);

Applications 2-tert-Butyl-1,3-diisopropylisourea is a useful synthetic intermediate in the synthesis of 5-Oxo Atorvastatin tert-Butyl Ester (O847160) which is a Boc-protected derivative of Atorvastatin (A791750, Ca Salt). 2-tert-Butyl-1,3-diisopropylisourea is also used as a reagent in the total synthesis of Citrafungin A which is an antifungal natural product.
References Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993); Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996); Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000); Calo, F., et al.: J. Org. Chem., 73, 9692 (2008)

Applications Hydroxypivalic acid methyl ester

Applications 8-Bromoguanosine (cas# 4016-63-1) is a compound useful in organic synthesis.
References Hu, H., et al.: Mol. Pharmacol., 69, 1542 (2006), Mallett, D., et al.: J. Pharm. Biomed. Anal., 49, 100 (2009),

Applications Bis[2-(2-mercaptobenzoyl)hydrazide] 2,2'-Dithiobis-benzoic Acid is an intermediate used in the synthesis of N,N’-Bis(2-mercaptobenzoyl)hydrazide (B481825), which is a selective inhibitor of HIV-1 integrase. Has no other effect on other retroviral targets, including reverse transcriptase, protease, and virus attachement, and exhibits no detectable activity against human topoisomerases I and II at concentrations that effectively inhibit integrase.
References Neamati, N., et al.: J. Med. Chem., 45, 5661 (2003)

Applications N1,O2'-Dimethyladenosine-d3 Monohydriodide is an intermediate in the synthesis of N6,O2'-Dimethyladenosine-d3 (D447417). N6,O2'-Dimethyladenosine-d3 is an isotopic analog of N6,O2'-Dimethyladenosine (D447415), a naturally occurring modified nucleoside in RNA. It was reported in the preparation of alkylated adenosines as antihypertensive agents.
References Yamada, T., Kageyama, K.: Eur. Pat. Appl. (1988), EP 269574 A2 19880601; Aduri, R., et al.: J. Chem. Theory Comput., 3, 1464 (2007)

Stability Light Sensitive
Applications Retinyl Retinoate is used in the treatment of skin diseases and disorders such as acne, psoriasis and photoaging.
References Kim, B. et al.: Int. J. Derm., 51, 733 (2012); Kim, J. et al.: Brit. J. Derm., 162, 497 (2010);

Applications 2-Amino-4-chloro-5-nitropyridine (cas# 24484-96-6) is a compound useful in organic synthesis.

Applications Labelled Anabaseine intermediate.

Applications N,N-Dimethyl-2,4-dinitro-1-naphthalenamine (cas# 39139-79-2) is a compound useful in organic synthesis.

Applications 10,11-Dihydrobenz[a]anthracene is an intermediate in the synthesis of phenols of Benz[a]anthracene (B183560).
References Fu, P.P.,e t al.: J. Org. Chem, 44, 4265 (1979)

Applications An intermediate for the synthesis of a benzimidazole PARP inhibitor I (succinate salt) (ABT-472).
References Denny, W., et al.: J. Med. Chem., 33, 814 (1990), Anon., et al.: Curr. Med. Chem., 10, 321 (2003),

Applications (3aα,4β,7aα)-4-(Acetyloxy)-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione is an intermediate in the synthesis of (3aα,4β,7aα)-3a,4,7,7a-Tetrahydro-4-hydroxy-1H-isoindole-1,3(2H)-dione (T293630), which is a metabolite of Captan (C175725), a fungicide, often added to pesticide mixtures used to control diseases among fruits, vegetables.
References Kukla, D. et al.: J. Agri. Food Chem., 43, 1224 (1995); Afful, S., et al.: Res. J. App. Sci., Eng. Technol., 2, 592 (2010), Engelen, K., et al.: J. Prot. Res., 9, 4919 (2010), Lagunas-Allue, L., et al.: Anal. Bioanal. Chem., 398, 1509 (2010),

Applications 5β-Dihydrocortisol 21-O-(1-Ethoxy Ethyl) Ether-d6 is an isotope labelled intermediate in the synthesis of Tetrahydro Cortisone-d6 (T293377), which is a normal mammalian metabolite of Cortisone (C696500).
References Schneider, et al.: J. Biol. Chem., 183, 365 (1950), Barkemeyer, et al.: Appl. Microbiol., 8, 237 (1960),