
Estándares farmacéuticos
Los estándares farmacéuticos son un conjunto integral de materiales de referencia esenciales para garantizar la seguridad, eficacia y calidad de los productos farmacéuticos. Esta categoría incluye estándares para ingredientes farmacéuticos activos (APIs), que son los componentes centrales responsables de los efectos terapéuticos. Además, abarca compuestos y metabolitos relevantes tanto para las industrias farmacéutica como veterinaria, proporcionando puntos de referencia para la medición y análisis precisos de estas sustancias. Los estándares de control de nitrosaminas son cruciales para detectar y mitigar las nitrosaminas potencialmente dañinas en las formulaciones de medicamentos. Los estándares de toxicología ayudan a evaluar la seguridad y los posibles efectos adversos de los compuestos farmacéuticos. Además, los estándares de activadores e inhibidores enzimáticos son vitales para la investigación y el desarrollo, permitiendo estudios precisos de las vías bioquímicas y los mecanismos de acción de los medicamentos. Estos estándares farmacéuticos son herramientas indispensables para el cumplimiento normativo, el control de calidad y la investigación, asegurando que los productos farmacéuticos cumplan con estrictos criterios de seguridad y eficacia.
Subcategorías de "Estándares farmacéuticos"
- APIs para investigación e impurezas(274.687 productos)
- Activadores e inhibidores de enzimas(2.827 productos)
- Nitrosaminas(2.606 productos)
- Compuestos y metabolitos farmacéuticos y veterinarios(2.776 productos)
- Toxicología(13.652 productos)
Se han encontrado 7836 productos de "Estándares farmacéuticos"
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3-(4-(2,3-Epoxypropoxy)phenyl)propionic Acid Methyl Ester
CAS:<p>Applications 3-(4-(2,3-Epoxypropoxy)phenyl)propionic Acid Methyl Ester is an intermediate in the synthesis of N-Ethyl Esmolol (E918045), which is an impurity of esmolol (E668000), which is a cardioselective β-adrenergic blocker. Antiarrhythmic.<br>References Gorczynski, R.J., et al.: J. Cardiovasc. Pharmacol., 5, 668 (1983), Yacobi, A., et al.: J. Pharm. Sci., 72, 711 (1983), Benfield, P., et al.: Drugs, 33, 392 (1987)<br></p>Fórmula:C13H16O4Forma y color:NeatPeso molecular:236.265-Methylcytosine (~90%)
CAS:Producto controlado<p>Applications 5-Methylcytosine (cas# 554-01-8) is a useful research chemical.<br></p>Fórmula:C5H7N3OPureza:~90%Forma y color:NeatPeso molecular:125.133-Cysteinylacetaminophen-D5 (major), Trifluoroacetic Acid Salt
CAS:Producto controlado<p>Applications 3-Cysteinylacetaminophen-D5 (major), Trifluoroacetic Acid Salt is deuterium labeled 3-Cysteinylacetaminophen Trifluoroacetic Acid Salt (C994750), which is a metabolite of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).Minimum isotopic incorporation d-3, no d-0 present. A representative lot has 64% isotopic incorporation at the 6-position, 89% at the 4-position.<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974) (3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)<br></p>Fórmula:C11H9D5N2O4S•C2HF3O2Forma y color:NeatPeso molecular:389.36Biotin Sulfone
CAS:Producto controlado<p>Applications Biotin Sulfone, is derivative of Biotin (B389040), which is a growth factor present in minute amounts in every living cell, and plays an indispensable role in numerous naturally occurring carboxylation reactions.<br>References du Vigneaud, et al.: J. Biol. Chem., 146, 475 (1942), Traub, et al.: Nature, 178, 649 (1956), Siegel, H., et al.: Experienta, 37, 789 (1981), Vesely, D.L., Science, 216, 1329 (1982), Hugues, M., et al.: Biochemistry, 31, 12 (1992),<br></p>Fórmula:C10H16N2O5SForma y color:NeatPeso molecular:276.31(S)-Ramelteon Metabolite M-II
CAS:Producto controlado<p>Applications S-Ramelteon Metabolite M-II is a metabolite of Ramelteon in serum (M-II).<br>References Karim, A., et al.: J. Clin. Pharmacol., 44, 1210 (2004); Prescott, E., et al.: Drug Metab. Rev., 36, 203 (2004); Kato, K., et al.: Neuropharmacology, 48, 301 (2005); Karim, A., et al.: J. Clin. Pharmacol., 46, 140 (2006)<br></p>Fórmula:C16H21NO3Forma y color:NeatPeso molecular:275.342-Hydroxy Oleic Acid
CAS:Producto controlado<p>Applications An oleic acid synthetic analog that is an effective non-toxic anticancer drug with a wide spectrum against different types of cancer. An antihypertensive.<br>References Llado, V. et al.: J. Cell. Molec. Med., 14, 659 (2010); Alemany, R. et al.: J. Lip. Res., 47, 1762 (2006); Martinez, J. et al.: J. Pharmacol. Exp. Therap., 315, 466 (2005);<br></p>Fórmula:C18H34O3Forma y color:Off White SolidPeso molecular:298.46Androsterone Sulfate Sodium Salt
CAS:Producto controladoFórmula:C19H29O5S·NaForma y color:White To Off-WhitePeso molecular:392.40Betamethasone Tripropionate
CAS:<p>Impurity Betamethasone Dipropionate EP Impurity G<br>Applications Betamethasone Tripropionate (Betamethasone Dipropionate EP Impurity G) is a Betamethasone (B327000) related compound.<br>References Grootveld, M., et al.: Biochem. Pharmacol., 37, 271 (1988), Chen, B., et al.: Steriods, 74, 30 (2009), Mikami, E., et al.: J. Pharm. Biomed. Anal., 28, 261 (2002),<br></p>Fórmula:C31H41FO8Forma y color:NeatPeso molecular:560.65Hydroxy Urea
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications An anti-neoplastic - inhibits ribonucleoside reductase and DNA replication. A potential therapy for sickle cell anemia which involves the nitrosylation of sickle cell hemoglobin. Horseradish peroxidase catalyzes nitric oxide formation from hydroxyurea in the presence of hydrogen peroxide.<br>References Ratcliffe, W., et al.: Lancet, 339, 164 (1992), Roodman, G., et al.: Cancer, 80, 1557 (1997), Horwitz, M., et al.: J. Clin. Endocrinol. Metab., 2003, 88, 1603 (2003),<br></p>Fórmula:CH4N2O2Forma y color:White SolidPeso molecular:76.055-Oxorosuvastatin Methyl Ester
CAS:<p>Applications 5-Oxorosuvastatin methyl ester is an intermediate in the synthesis of Rosuvasatatin (calcium salt: R700500), a 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor that decreases high-sensitivity C-reactive protein (hsCRP) and cholesterol concentrations in the blood.<br>References McTaggart, F., et al.: Am. J. Cardiol., 87, 28 (2001); Ridker, P., et al.: Lancet, 373, 1175 (2009)<br></p>Fórmula:C23H28FN3O6SForma y color:Yellow SolidPeso molecular:493.5519-Norandrosterone
CAS:Producto controlado<p>Applications 19-Norandrosterone is the oxidized byproduct of Nandrolone (N315000), an anabolic steroid that is present naturally in the human body.<br>References Jiang, J.Q., et al.: J. Food. Sci., 77, 63 (2012); Delgadillo, M.A., et al.: J. Chromatograph. Anal. Technol. Biomed. Life. Sci., 897 (2012);<br></p>Fórmula:C18H28O2Forma y color:NeatPeso molecular:276.414-Methyl-2-(4-(trifluoromethyl)phenyl)thiazole-5-carboxylic Acid
CAS:Producto controlado<p>Applications 4-methyl-2-(4-(trifluoromethyl)phenyl)thiazole-5-carboxylic acid (cas# 144059-86-9) is a useful research chemical.<br></p>Fórmula:C12H8F3NO2SForma y color:NeatPeso molecular:287.261,2,4-Trioctyl Ester 1,2,4-Benzenetricarboxylic Acid-d51
CAS:Producto controlado<p>Applications Isotope labelled 1,2,4-Trioctyl Ester 1,2,4-Benzenetricarboxylic Acid is a widely used and often incorporated in plasticizer for PVC for a higher molecular weight.<br>References Jones, C., et al.: Int. J. Artificial. Organs., 12, 466 (1989); Khang, G., et al.: Bio-Med. Mater. Engineer., 12, 135 (2002);<br></p>Fórmula:C33D51H3O6Forma y color:NeatPeso molecular:598.092Desloratadine N-Hydroxypiperidine
CAS:<p>Applications A related compound of Desloratadine (D290250).<br>References Krishna, K., et al.: J. Pharm. Biomed. Anal., 32, 29 (2003), Qi, M., et al.: J. Pharm. Biomed. Anal., 38, 355 (2005),<br></p>Fórmula:C19H19ClN2OForma y color:NeatPeso molecular:326.82Potassium Bromide
CAS:<p>Applications Potassium bromide is an ionic compound that is commonly used in chemistry to form a pellet that can be used to analyze a number of compounds by means of infrared spectroscopy. Potassium bromide is also used as an anticonvulsant to treat refractory seizures in humans and dogs.<br>References Kirkland, J.: Anal. Chem., 27, 1537 (1955); Korinthenberg, R., et al.: J. Child Neuro., 22, 414 (2007); Wilberley, S., et al.: Anal. Chem., 29, 210 (1957); Yohn, S., et al.: J. Am. Vet. Med. Ass., 201, 468 (1992)<br></p>Fórmula:BrKForma y color:White To Off-WhitePeso molecular:119.00Azelastine N-Oxide (Mixture of Diastereomers)
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications A metabolite of Azelastine (A808250).<br>References Heinemann, U. et al.: J. Chrom. B Anal. Tech. Biomed. Life Sci., 793, 389 (2003); Tasaka, K., et al.: Arzneim.-Forsch., 29, 488 (1979);<br></p>Fórmula:C22H24ClN3O2Forma y color:NeatPeso molecular:397.90Pemetrexed acid
CAS:Producto controladoFórmula:C15H14N4O3Forma y color:Off-WhitePeso molecular:298.30Vitamin K1 Hydroxide
CAS:Producto controlado<p>Stability Temperature and Light Sensitive, unstable in solution<br>Applications Vitamin K1 Hydroxide is a derivative of Vitamin K1 (V676080), which occurs widely in green plants, algae, and photosynthetic bacteria.<br>References Hassan, M.M.A., et al.: Anal. Profiles Drug Subs., 17, 449 (1988), Breton, J., et al.: Biochemistry, 33, 12405 (1994), Dowd, P., et al.: Science, 269, 1684 (1995),<br></p>Fórmula:C31H46O3Forma y color:NeatPeso molecular:466.7Hydroxydehydro Nifedipine Carboxylate
CAS:Producto controladoFórmula:C16H14N2O7Forma y color:NeatPeso molecular:346.29Caffeidine Acid Sodium Salt
CAS:Producto controlado<p>Applications Caffeidine Acid is a potential degradation product from the hydrolysis of Caffeine (C080100) under alkaline environment.<br>References Zubair, U.M., et al.: Anal. Profiles Drug Subs., 15, 71 (1986); Cherrah, Y., et al.: Biochem. Pharmacol., 37, 1311 (1988);<br></p>Fórmula:C8H11N4O3·NaForma y color:NeatPeso molecular:234.19
