Estándares farmacéuticos
Los estándares farmacéuticos son un conjunto integral de materiales de referencia esenciales para garantizar la seguridad, eficacia y calidad de los productos farmacéuticos. Esta categoría incluye estándares para ingredientes farmacéuticos activos (APIs), que son los componentes centrales responsables de los efectos terapéuticos. Además, abarca compuestos y metabolitos relevantes tanto para las industrias farmacéutica como veterinaria, proporcionando puntos de referencia para la medición y análisis precisos de estas sustancias. Los estándares de control de nitrosaminas son cruciales para detectar y mitigar las nitrosaminas potencialmente dañinas en las formulaciones de medicamentos. Los estándares de toxicología ayudan a evaluar la seguridad y los posibles efectos adversos de los compuestos farmacéuticos. Además, los estándares de activadores e inhibidores enzimáticos son vitales para la investigación y el desarrollo, permitiendo estudios precisos de las vías bioquímicas y los mecanismos de acción de los medicamentos. Estos estándares farmacéuticos son herramientas indispensables para el cumplimiento normativo, el control de calidad y la investigación, asegurando que los productos farmacéuticos cumplan con estrictos criterios de seguridad y eficacia.
Subcategorías de "Estándares farmacéuticos"
- APIs para investigación e impurezas(273.774 productos)
- Activadores e inhibidores de enzimas(2.827 productos)
- Nitrosaminas(2.606 productos)
- Compuestos y metabolitos farmacéuticos y veterinarios(2.613 productos)
- Toxicología(13.652 productos)
Se han encontrado 7836 productos de "Estándares farmacéuticos"
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4-(4-Nitrophenyl)-3-morpholinone
CAS:Producto controladoFórmula:C10H10N2O4Forma y color:NeatPeso molecular:222.204'-hydroxy-3',5'-diiodo-[1,1'-Biphenyl]-4-carbonitrile
CAS:Producto controlado<p>Applications 4'-hydroxy-3',5'-diiodo-[1,1'-Biphenyl]-4-carbonitrile is a useful building block compound, and has been used in the preparation of plasminogen activator inhibitor antagonists.<br>References Madison, E. L.; et al.: US 6677473 (2004).<br></p>Fórmula:C13H7I2NOForma y color:NeatPeso molecular:447.01Hydroxy Dehydro Nifedipine Lactone
CAS:Producto controladoFórmula:C16H12N2O6Forma y color:NeatPeso molecular:328.28Nicergoline-d3
CAS:Producto controlado<p>Applications Nicergoline-d3 is the labeled analogue of Nicergoline(N394550), a drug used for age-dependent cognitive impairment such as Alzheimers disease and other types of dementia.<br>References Caraci, F., et. al.: Brain Res., 1047, 30 (2005); Mizuno, T., et. al.: Brain Res., 1066, 78 (2005)<br></p>Fórmula:C24D3H23BrN3O3Forma y color:NeatPeso molecular:487.4044-(S)-1-Des(methylamine)-1-oxo-2-(R,S)-hydroxy Sertraline
CAS:Producto controladoFórmula:C16H12Cl2O2Forma y color:NeatPeso molecular:307.17Indole-3-acetic acid Sodium Salt
CAS:Producto controlado<p>Stability Temperature Sensitive<br>Applications Indole-3-acetic acid is a plant growth regulator. It induces cell division and cell elongation that promotes plant growth.<br>References Fawcett, C., et al.: Nature, 178, 972 (1956); Fawcett, C., et al.: Annals Appl. Bio., 43, 342 (1955); Korshak, V., et al.:Vysokomolekulyarnye Soedineniya, Seriya B: Kratkie Soobshcheniya, 22, 791 (1980)<br></p>Fórmula:C10H8NNaO2Forma y color:White To Off-WhitePeso molecular:197.17Perilla Ketone
CAS:Producto controlado<p>Stability Light Sensitive<br>Applications Perilla Ketone is an oil from Perilla frutescens which is very toxic as it is a potent pulmonary edemagenic agent for laboratory animals and livestock. This compound is commonly used in oriental foods.<br>References Wilson, B.J., et al.: Science, 197, 573 (1997)<br></p>Fórmula:C10H14O2Forma y color:NeatPeso molecular:166.22(±)-trans-α-Bergamotene
CAS:Producto controlado<p>Applications (±)-trans-α-Bergamotene is an essential oil from medicinal plants of Cameroon.<br>References Boyom, F. F., et al.: Phytochem., 64, 1269 (2003);<br></p>Fórmula:C15H24Forma y color:NeatPeso molecular:204.3511,3-Diacetyl Aloe-emodin
CAS:Producto controlado<p>Applications 1,3-Diacetyl Aloe-emodin is an intermediate in the synthesis of Aloe Emodin 8-Glucoside which is a anthraquinone glycoside that was investigated for antioxidant activities and neuroprotective properties.<br>References El-Toumy, S.A., et al.: Carb. Res. 360, 47 (2012); Xiang, L., et al: TsingHua. Sci. Tech., 10, 426 (2005); Shi, Y.Q., et al: Anticancer. Res., 21, 2847 (2001);<br></p>Fórmula:C10H17BO2Forma y color:NeatPeso molecular:180.052Terazosin-md
Producto controlado<p>Applications Terazosin-md is an analog of Terazosin (T105000) which is an α1-adrenergic receptor antagonist alleviating organ damage in studies done on rodent models of stroke and sepsis and has potential to be used for treatment for diseases.<br>References Chen, X., et al.: Nat. Chem. Biol, 11, 19 (2015)<br></p>Fórmula:C20H26N4O4Forma y color:NeatPeso molecular:386.445Thiamine Acetate Hydrochloride
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications Thiamine (T344185) impurity.<br>References Warnock, L., et al.: Anal. Biochem., 126, 394 (1982), Royer-Morrot, J., et al.: Eur. J. Clin. Pharmacol., 42, 219 (1992),<br></p>Fórmula:C14H20Cl2N4O2SForma y color:WhitePeso molecular:379.31Boldenone Propionate
CAS:Producto controlado<p>Applications Boldenone Propionate is a metabolite of Boldenone (B675100), which is an anabolic steroid.<br>References Watanabe, K., et al.: J. Appl. Bacteriol., 62, 151 (1987) ; Liu, W., et al.: J. Ind. Microbiol., 13, 167 (1994) ; Barthakur, S., et al.: J. Basic Microbiol., 36, 383 (1996); Grinenko, G., et al.: Pharmaceut. Chem. J., 36, 510 (2002) ; de Brabander, H., et al.: Food Addit. Contam., 21, 515 (2004); Le Bizec, B., et al.: Steroids, 71, 1078 (2006);<br></p>Fórmula:C22H30O3Forma y color:Off-WhitePeso molecular:342.47N-(n-Butanesulfonyl)-O-[4-(4-pyridinyl)-butyl]-(S)-tyrosine
CAS:<p>Applications Tirofiban intermediate.<br></p>Fórmula:C22H30N2O5SForma y color:NeatPeso molecular:434.557α-Hydroxy-4-cholesten-3-one
CAS:<p>Applications 7α-Hydroxy-4-cholesten-3-one is a metabolite of Cholesterol (C432501).<br>References Connor, W., et al.: J, Clin. Invest., 48, 1363 (1969), Nestel, P., et al.: Metabolism, 24, 189 (1975), Ellegard, L., et al.: Eur. J. Clin. Nutr., 45, 451 (1991), Pedersen, A., et al.: J. Lipid Res., 41, 1901 (2000),<br></p>Fórmula:C27H44O2Forma y color:NeatPeso molecular:400.644-Aminoacetophenone
CAS:Producto controlado<p>Applications A novel utilization of aminophenone derivative in toxicology, for treating intoxications with cyanogenic toxic substances.<br>References Donoghue, N., et al.: Eur. J. Biochem., 60, 1 (1975), Chen, Y., et al.: J. Bacteriol., 170, 781 (1988),<br></p>Fórmula:C8H9NOForma y color:Yellow SolidPeso molecular:135.163-Dehydro Retinal
CAS:Producto controlado<p>Stability Light Sensitive, Temperature Sensitive<br>Applications An oxidized derivative of the visual pigment carotenoid.<br>References Wada, A., et al.: Chem. Pharm. Bull., 56, 112 (2008), Smolensky, E., et al.: Biochem., 48, 9170 (2009),<br></p>Fórmula:C20H26OForma y color:NeatPeso molecular:282.42Melphalan
CAS:Producto controlado<p>Applications Melphalan is an antineoplastic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ross, W.C.J., et al.: Biochem. Pharmacol., 13, 969 (1964); Donelli, M.G., et al.: J. Pharm. Pharmacol., 18, 760 (1966), Furner, R.L., et al.: Cancer Treat. Rep., 64, 559 (1980),<br></p>Fórmula:C13H18Cl2N2O2Forma y color:NeatPeso molecular:305.20Rosuvastatin Ethyl Ester
CAS:<p>Applications Rosuvastatin ethyl ester (CAS# 851443-04-4) is an intermediate formed during the synthetic preparation of rosuvastatin, a pharmaceutical used to manage LDL cholesterol.<br>References Sterk, D.; et al.: Tetrahedron Lett., 57, 1338 (2016); Olsson, A. G.; et al.: Am. Heart J., 144, 1044 (2002).<br></p>Fórmula:C24H32FN3O6SForma y color:Off-White To Light BeigePeso molecular:509.59Stigmasta-3,5-diene
CAS:<p>Applications Stigmasta-3,5-diene is one of the components found in vegetable oil after refining.<br>References Lanzon, A., et al.: J. Am. Oil Chemist Soc., 71, 285 (1994); Cert, A., et al.: Food Chem., 49, 287 (1994)<br></p>Fórmula:C29H48·C28H46Forma y color:NeatPeso molecular:779.36Hydroflumethiazide
CAS:Producto controlado<p>Applications Antihypertensive; diuretic.<br>References Piala, J.J., et al.: J. Pharmacol. Exp. Ther., 134, 273 (1961), Orzech, C.E., et al.: Anal. Profiles Drug Subs., 7, 297 (1978),<br></p>Fórmula:C8H8F3N3O4S2Forma y color:NeatPeso molecular:331.29Glycochenodeoxycholic Acid 3-Sulfate Disodium Salt
CAS:<p>Stability Hygroscopic<br>Applications A bile salt formed in the liver from chenodeoxycholate and glycine, usually as the sodium salt. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is a cholagogue and choleretic.<br>References Parmentier, G. , et al.: Steroids, 30, 583 (1977), Tserng, K.Y., et al.: Lipids, 13, 479 (1978),<br></p>Fórmula:C26H41NNa2O8SForma y color:White To Off-WhitePeso molecular:573.65Demethyl Benzydamine Hydrochloride
CAS:Producto controlado<p>Applications A metabolite of Benzydamine (B209950).<br>References Kataoka, S., et al.: Chem. Pharma. Bull., 21, 358 (1973),<br></p>Fórmula:C18H22ClN3OForma y color:Off White SolidPeso molecular:331.84Ouabain-d3 (Major)
CAS:Producto controlado<p>Applications Labelled Ouabain (O714500). A cardiac glycoside that inhibits Na(+)/K(+) ATPase. It regulates transcription of MDR (increase, Pgp) and MRP (increase MRP1 and decrease CFTR, cyctic fibrosis transport receptor or cAMP-activated Cl- channel) genes, also alters localization of MRP1.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Padilha, A.S. et al.: Clin. Exp. Pharmacol. Physiol., 35, 801 (2008); Blaustein, M.P. et al.: Clin. Exp. Hypertens. 20, 691 (1998); van Huysse, J.W. et al.: Clin. Exp. Hypertens. 20, 657 (1998);<br></p>Fórmula:C29H41D3O12Forma y color:White To Off-WhitePeso molecular:587.67Mycophenolic Acid Phenolic β-D-Glucoside
CAS:Producto controladoFórmula:C23H30O11Forma y color:White To Off-WhitePeso molecular:482.48Dipropofol
CAS:<p>Impurity Propofol EP Impurity E; Propofol USP Related Compound A<br>Applications Dipropofol (Propofol EP Impurity E) is a dimeric derivative of Propofol (P829750). Dipropofol is an antibacterial agent with strong activity againts Gram-positive bacteria. Dipropofol also displays antioxidant and radical scavenging activity. Propofol USP Related Compound A.<br>References Ogata, M. et al.: Chem. Pharm. Bull., 53, 344 (2005); Ogata, M. et al.: Biol. Pharmac. Bull., 30, 1565 (2007);<br></p>Fórmula:C24H34O2Forma y color:NeatPeso molecular:354.53Amlodipine Dimethyl Ester
CAS:<p>Impurity Amlodipine EP Impurity F / Amlodipine USP Related Compound F<br>Applications Amlodipine Besilate (A633500) impurity. Amlodipine EP Impurity F<br>References Coburn, R., et al.: J. Med. Chem., 31, 2103 (1988), Gupta, S., et al.: Eur. J. Med. Chem., 38, 867 (2003), Vazzana, I., et al.: J. Med. Chem., 50, 334 (2007),<br></p>Fórmula:C19H23ClN2O5Forma y color:Light Yellow To YellowPeso molecular:394.85Des-4-fluorobenzyl Mosapride
CAS:Producto controlado<p>Applications The major metabolite of Mosapride (M731000).<br>References Somogyi, A., et al.: Clin. Pharmacokinet., 8, 463 (1983), Cashman, J., et al.: Drug Metab. Dispos., 21, 587 (1993), Berkman, C., et al.: Biochem. Pharmacol., 50, 565(1995), Blake, B., et al.: Xenobiotica, 25, 377 (1995),<br></p>Fórmula:C14H20ClN3O3Forma y color:NeatPeso molecular:313.78Anastrozole Acid Amide
<p>Applications Anastrozole Acid Amide is a derivative of Anastrozole (A637425), an aromatase inhibitor. Used as an antineoplastic.<br>References Plourde, P.V., et al.: Breast Cancer Res. Treat., 30, 103 (1994), Buzdar, A.U., et al.: Cancer, 79, 730 (1997)<br></p>Fórmula:C17H22N4O3Forma y color:NeatPeso molecular:330.38Ramiprilat(Mixture of Diastereoisomers)
CAS:Producto controladoFórmula:C21H28N2O5Forma y color:NeatPeso molecular:388.46Diacetyl 2,4-Dinitrophenylhydrazone
CAS:<p>Applications: 2,4-Dinitrophenylhydrazone (DNPH) derivative. Also, it is used in TLC as internal standards.<br>References Lindsay, R.C., et al.: J. Food Sci., 29, 266 (1964),<br></p>Fórmula:C10H10N4O5Forma y color:NeatPeso molecular:266.215α-Pregnane-3β,20(S)-diol
CAS:Producto controlado<p>Applications 5α-Pregnane-3β,20(S)-diol, is a metabolite of Progesterone (P755900).<br>References Beall, et al.: Biochem. J., 31, 35 (1937), Okuda, A., et al.: J. Biol. Chem., 259, 7519 (1984), Russell, D., et al.: Biochemistry, 31, 4737 (1992), Kondo, K., et al.: Eur. J. Biochem., 219, 357 (1994), Westerbacka, J., et al.: J. Clin. Endocrinol. Metab., 88, 4924 (2003),<br></p>Fórmula:C21H36O2Forma y color:NeatPeso molecular:320.51Ethyl Cinnamate
CAS:<p>Applications Ethyl Cinnamate, is used in the preparation of polymer-encapsulated osmonium used as a catalyst for the dihydroxylation of alkenes and preparation of a camptothecin intermediate, anticancer drug. Also used in the synthesis of substrate specific ERK1/2 inhibitors used to induce apoptosis and inhibit cell proliferation.<br>References Akiyama, R. et al.: RSC Adv., 2, 7456 (2012); Li, Q. et al.: Bioorg. Med. Chem. Lett., 19, 6042 (2009);<br></p>Fórmula:C11H12O2Forma y color:Colourless To YellowPeso molecular:176.21Bivalirudin α-ASPA 9 Analog Trifluoroacetic Acid Salt (Impurity)
<p>Applications Impurity of Bivalirudin, a direct thrombin inhibitor acting as an anticoagulant through inhibition of the enzyme thrombin.<br>References Bertrand, O. et al.: Am. J. Cardio., 110, 599 (2012); Patti, G. et al.: Am. J. Cardio., 110, 478 (2012);<br></p>Fórmula:C98H137N23O34•xC2HF3O2Forma y color:NeatPeso molecular:2181.271α-(Chloromethyl) Chlormadinone Acetate
CAS:Producto controlado<p>(1α)-17-(Acetyloxy)-6-chloro-1-(chloromethyl)-pregna-4,6-<br>diene-3,20-dione; 6-Chloro-1α-(chloromethyl)-17-<br>hydroxypregna-4,6-diene-3,20-dione Acetate; Cyproterone<br>Acetate EP Impurity C</p>Fórmula:C24H30Cl2O4Forma y color:NeatPeso molecular:453.40Muraglitazar
CAS:Producto controlado<p>Applications It is a peroxisome proliferator-activated receptor (PPAR) α/γ dual agonist.<br>References Barlocco, D., et al.: Curr. Opin. Invest. Drugs, 6, 427 (2005), Devasthale, P.V., et al.: J. Med. Chem., 48, 2248 (2005), Kendall, D.M., et al.: Diabetes care, 29, 1016 (2006),<br></p>Fórmula:C29H28N2O7Forma y color:NeatPeso molecular:516.54γ-Butyrobetaine-d9
CAS:Producto controlado<p>Applications γ-Butyrobetaine-d9 is the labelled analogue of γ-Butyrobetaine, a synthetic carnitine related compound used as a transporter substrate in the cloning and sequencing of human carnitine transporter 2 (CT2).<br>References Enomoto, A. et al.: J. Biol. Chem., 277, 36262 (2002)<br></p>Fórmula:C72H9H7NO2Forma y color:NeatPeso molecular:155.264-Hydroxy Estrone 1-N7-Guanine
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications 4-Hydroxy Estrone 1-N7-Guanine is an estrogen metabolite formed with DNA which can lead to the mutations that initiate breast, prostate, and other types of cancer. Estrogen-DNA depurinating adducts as biomarkers of cancer risk and their use in cancer detection and prevention.<br>References Chakravarti, D., et al.: Mutat. Res., 456, 17 (2000), Liehr, J., et al.: Endocr. Rev., 21, 4054 (2000), Chakravarti, D., et al.: Oncogene, 20, 7945 (2001), Cavalieri, E., et al.: Chem. Res. Toxicol., 14, 1041 (2002),<br></p>Fórmula:C23H25N5O4Forma y color:NeatPeso molecular:435.48CRL-40,941
CAS:Producto controlado<p>Applications CRL-40,941 is a wakefulness-promoting agent. It was found to produce antiaggressive effects in animals.<br>References Lafon, L.: US4489095 (A) (1984)<br></p>Fórmula:C15H13F2NO3SForma y color:WhitePeso molecular:325.33Imipenem, Monohydrate
CAS:Producto controladoFórmula:C12H17N3O4S·H2OForma y color:White To Light YellowPeso molecular:317.366-Hydroxynaphthalene-2-sulfonic Acid Potassium Salt
CAS:<p>Applications 6-Hydroxynaphthalene-2-sulfonic Acid Potassium Salt is used the in the synthesis of azo dyes and pigments.<br>References Gao, Pu. et al., Dyes Pigm. 179, 108376(2020);<br></p>Fórmula:C10H7O4S·KForma y color:NeatPeso molecular:262.32357α-Thiomethyl Spironolactone-d7 (Major)
CAS:Producto controlado<p>Applications A labelled metabolite of Spironolactone.<br>References Gochman, N., et al.: J. Pharmacol. Exp. Ther., 135, 312 (1962), Tori, K., et al.: Steroids, 4, 713 (1964), Solymoss, B., et al.: Toxicol. Appli. Pharmacol., 18, 586 (1971),<br></p>Fórmula:C23H25D7O3SForma y color:NeatPeso molecular:395.61Etomidate Hydrochloride
CAS:Producto controlado<p>Applications (cas# 53188-20-8) is a useful research chemical.<br></p>Fórmula:C14H17ClN2O2Forma y color:NeatPeso molecular:280.75rac-syn N,N-Diethyl Norephedrine
CAS:Producto controlado<p>Applications The main basic metabolite of Diethylpropione.<br>References Banci, F., et al.: Arzneim.-Forsch., 21, 1616 (1971), Mikhailova, D., et al.: Eur. J. Med. Chem., 13, 49 (1978),<br></p>Fórmula:C13H21NOForma y color:NeatPeso molecular:207.31Betamethasone 6α-Bromo 17-Valerate
Producto controlado<p>Applications Betamethasone 6α-Bromo 17-Valerate is an impurity of Betamethasone (B327000), which is a glucocorticoid used as an anti-inflammatory agent.<br>References Ferrante, M.G., et al.: Anal. Profiles Drug Subs., 6, 43 (1977), Li, A., et al.: Chem. Biol. Interact., 142, 7 (2002), Cruz-Monteagudo, M., et al.: Eur. J. Med. Chem., 40, 1030 (2005), Rothfuss, A., et al.: Chem. Res. Toxicol., 19, 1313 (2006),<br></p>Fórmula:C27H36BrFO6Forma y color:NeatPeso molecular:555.47Chenodeoxycholic acid-3-β-D-glucuronide
CAS:Producto controladoFórmula:C30H48O10Forma y color:White To Off-WhitePeso molecular:568.7Dimethyl 2,7-Naphthalenedicarboxylate
CAS:Producto controlado<p>Applications Dimethyl 2,7-Naphthalenedicarboxylate (cas# 2549-47-5) is a useful research chemical.<br></p>Fórmula:C14H12O4Forma y color:Off White To Light YellowPeso molecular:244.243Petromyzonol 24-Sulfate Sodium Salt
CAS:Producto controladoFórmula:C24H41O7S·NaForma y color:NeatPeso molecular:496.63
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