Estándares farmacéuticos

Stability Air Sensitive
Applications 1,8-Diaminonaphthalene is used as a reagent/ligand in the synthesis of transition metal tetraazamacrocyclic complexes as potent antimicrobial and antioxidant agents.
References Rathi, P. and Singh, D.P.: Pharma Chemica, 6, 203 (2014)

Applications Dye precursor and a potential building block for laboratory research.
References Jia, Di, et al.: Guisuanyan Tongbao, 20(Suppl.), 20-21 (2001)

Applications p-Aminosulfonyldihydrocinnamic acid

Applications 5-Iodovanillin is used in laccase catalyzed synthesis of iodinated phenolic compounds with antifungal activity. Molecular modeling studies of interaction between plasmid DNA (pBR322) and dendritic antioxidants.
References Ihssen, J., et al.: PLoS One, 9, e89924 (2014); Chhetri, P., et al.: J. Cancer Sci.Ther., 3, 220 (2011)

Applications N-Ethyl-N-pentyl-β-alanine is a compound useful in organic synthesis.

Applications 5,6,7,8-Tetrahydro-1-naphthalenol was used as a reagent in the synthesis of phosphonamidate and phosphonodiamidate prodrugs of adefovir and tenofovir which are used in the treatment of HIV infections. Also used in the synthesis of tetrahydronaphthalene-1-ol derivatives which were found to be promising potent antitumor agents.
References Pertusati, F., et al.: Eur. J. Med. Chem., 78, 259 (2014); Dong, Y., et al.: Bioorg. Med. Chem. Lett., 19, 6289 (2009);

Stability Hygroscopic
Applications A labelled metabolite from endophytes of the medicinal plant Erythrina crista-galli.
References Stadler, M., et al.: Planta Med., 60, 128 (1994), Kopcke, B., et al.: Phytochemistry, 60, 709 (2002), Chu, M., et al.: J. Nat. Prod., 66, 1527 (2003), Weber, D., et al.: J. Antibiot., 57, 559 (2004),

Applications 1,4-Di(methyl-d3)-naphthalene has been used in the preparation of di(trideuteriomethyl)naphthalene derivatives. 1,4-Di(methyl-d3)-naphthalene is a labeled analogue of 1,4-Dimethylnaphthalene (D476380), a polycyclic aromatic hydrocarbon (PAH) that has been found to retard the development of epidermoid carcinomas in hamster buccal pouch and alter the genes associated with the maintenance of a G1/S phase block possibly through the induction of the cell cycle inhibitors KRP1 and KRP2 in potatoes.
References Dizabo, P., et. al.: J. Labelled Compd., 2, 272 (1966); Malament, D.S., Shklar, G.: Carcinogenesis, 2, 723 (1981); Campbell, M.A., et. al.: Fuct. Interg. Genomics, 12, 533 (2012); Andrysik, Z., et. al.: Mutat. Res-Fund. Mol. M., 714, 53 (2011)

Applications Indole-2,4,5,6,7-d5-3-acetic Acid is an isotopic analog of Indoleacetic Acid (I577340) which is the most common and naturally occuring plant hormone in the auxin class of hormones. It effects cell elongation, cell division as well as plant growth and development.

Applications β-(p-Nitrophenyl)ethyl Bromide-d4 (cas# 1794971-35-9) is a compound useful in organic synthesis.

Applications Adenosine-2-d1 (CAS# 109923-50-4) is a useful isotopically labeled research compound.

Stability Moisture Sensitive
Applications 1,2-NaphthalicAnhydride (cas# 5343-99-7) is a useful research chemical.