Glycoscience

<p>Applications L-Ribulose is a rare sugar produced mainly from the abundant L-arabinose via enzymatic conversion.<br>References Liu, X. et al.: J. Agri. Food Chem., 67, 4868 (2019);<br></p>

<p>Applications 1,6-Hexane-1,1,6,6-d4-diamine (CAS# 115797-49-4) is a useful isotopically labeled research compound.<br></p>

<p>Applications A novel glucosylation enzyme.<br>References Kuriki, T., et al.: J. Biosci. Bioeng., 87, 557 (1999), Meulenbeld, G., et al.: Biotechnol. Bioeng., 70, 363 (2000), Moon, Y., et al.: J. Agric. Food Chem., 54, 1230 (2006),<br></p>

2,4-Dihydroxy-2-hydromethylbutanoic acid-1,4-lactone is a hydroxy anion that can be synthesized by the lactonization of 2,4-dihydroxybutanoic acid. The compound has been used to produce polymeric adsorbents for chromatographic purposes.

2,3,4,6-Tetra-O-benzyl-1-deoxynojirimycin hydrochloric acid salt is a synthetic monosaccharide. It was originally synthesized by the methylation of a native oligosaccharide before being subjected to click chemistry. The resulting product is a complex carbohydrate with an aromatic ring in place of the sugar alcohol moiety. 2,3,4,6-Tetra-O-benzyl-1-deoxynojirimycin hydrochloric acid salt has CAS number 72983-76-7 and is soluble in water. This product is also available as a custom synthesis service and can be modified to meet your needs.

1,2,3,6-Tetra-O-acetyl-4-O-[2,3,6-tri-O-acetyl-4-O-(2,3,4,6 tetra-O-acetyl bDglucopyranosyl)-bDglucopyra nosyl]-bDthioglucopyranose (1) is a sugar with the chemical formula C36H62N8O24. It was first synthesized by the group of L. W. F. Heckel in 1956 and its structure was elucidated by X. Miettinen in 1957. 1 is a complex carbohydrate with a glycosidic linkage to 4 as well as an acetate ester at position 6. The compound has been modified with methyl groups at positions 2 and 3 to form 1,2,3,6 tetra O acetyl 4 O methyl 2 O methyl 3 O methyl 6 O eth

<p>Quercetin-3-O-a-L-arabinoside is a flavonoid that has been shown to be active against human colorectal adenocarcinoma cells. Quercetin 3-O-a-L-arabinoside inhibits the proliferation of hl60 cells by inducing apoptosis and inhibiting protein synthesis. The biological properties of quercetin 3-O-a-L-arabinoside are not well understood, but it may work as an antioxidant due to its ability to scavenge free radicals. Quercetin 3-O-a-L-arabinoside has also been found to have antimicrobial activity against bacteria, fungi, and viruses. Quercetin 3 O a L arabinoside is able to inhibit the growth of various strains of Mycobacterium tuberculosis, including drug resistant strains. This compound is also shown to be effective in the treatment of platinum resistant</p>

<p>N-(2-Fluorobenzyliden)imino-2,3,4,6-tetra-O-pivaloyl-b-D-glucopyranoside is a custom synthesis of a high purity glycosylated oligosaccharide. It is modified with fluorine and has a methyl group on the 2' position of the sugar. The CAS number for this product is 1093457-52-1.</p>

2-(3,4-Dihydroxyphenyl)ethyl b-D-glucopyranoside (2,3,4-DHPEB) is a naturally occurring phenolic acid. It has been shown to have antidepressant activity in mice and rats. 2,3,4-DHPEB inhibits the growth of Streptococcus faecalis by inhibiting fatty acid biosynthesis. This compound also has anti-inflammatory properties that may be due to its ability to inhibit prostaglandin synthesis. 2,3,4-DHPEB is a ligand for PPAR receptors and activates their transcriptional activity in cells. It has been shown to have chemopreventive effects against colon cancer cell lines and is able to induce apoptosis in tumor cells.

<p>2,3,4,6-Tetra-O-pivaloyl-D-mannopyranosyl fluoride is a carbohydrate that is synthesized by the modification of D-mannose with 4,6-dichlorohexanoic acid. It is a white powder with a melting point of 170°C. 2,3,4,6-Tetra-O-pivaloyl-D-mannopyranosyl fluoride can be used as a monosaccharide for glycosylation reactions or as an intermediate for custom synthesis. This product has been methylated and glycosylated before the final purification process. It has a high purity level and can be used in Click chemistry reactions.</p>

2-Acetamido-2-deoxy-3-O-(a-D-galactopyranosyl)-D-galactopyranose is a high purity, custom synthesis sugar that is modified with fluorination, glycosylation, and methylation. It has the CAS number 60283-31-0 and can be used in the modification of oligosaccharides and monosaccharides. This carbohydrate can be found in complex carbohydrates.

(1R) -1- [(2S, 3R) - N-Benzyl-3- hydroxy- 1- azetidinyl] -1, 2- ethanediol is a synthetic product that can be custom synthesized. It has been used in glycosylation reactions to produce oligosaccharides and monosaccharides. The chemical composition of the product is: C6H10O5 (CAS No. ).

2-Amino-2-deoxy-3-O-methyl-D-glucose is a modified sugar that has been synthesized by the methylation of D-glucose. This product is often used as a building block in glycosylation, which is the process of adding sugars to proteins or polysaccharides. The modification of this carbohydrate makes it resistant to hydrolysis and oxidation reactions, making it suitable for use in pharmaceuticals and other applications. 2-Amino-2-deoxy-3-O-methyl-D-glucose can be fluorinated to produce 2-(Fluoro)amino 2 deoxy 3 O methyl D glucose, which has been shown to have antihypertensive effects in rats with high blood pressure. This product can also be modified with click chemistry to produce 2-[(Azidomethyl)amino]-2 deoxy 3 O methyl D glucose, which can be used

N- [[(2S, 3S, 4R) - 4- [(Acetyloxy) methyl] - 3- (phenylmethoxy) - 1-acetamide is a synthetic glycoside. It has been modified for fluorination and methylation. The complex carbohydrate has been synthesized with high purity and it has a CAS No..

<p>(-)-isolariciresinol-2a-O-b-D-xylopyranoside is a methylated saccharide that is used in the synthesis of complex carbohydrates. It is synthesized by reacting an aldehyde with an alcohol, and it has been modified using click chemistry. The product is purified to be at least 98% pure, and it can be custom synthesized to order. (-)-isolariciresinol-2a-O-b-D-xylopyranoside can be fluorinated for use as a fluorescent probe for various applications. It has a CAS number of 564964-92-1.</p>

7,9-Di-O-acetyl-N-glycolyl-8-O-methylneuraminic acid is a synthetic glycolylneuraminic acid analogue that can be used in the treatment of bacterial infections. It is a prodrug that is converted to glycolylneuraminic acid by monoclonal antibody and other enzymes. 7,9-Di-O-acetyl-N-glycolyl-8-O-methylneuraminic acid inhibits the activity of necrosis factor (TNF) by binding to its receptor, thereby preventing TNF from binding to cells and stimulating inflammation. This compound has been shown to be effective against many bacteria including methicillin resistant Staphylococcus aureus (MRSA). Techniques used for the synthesis include high performance liquid chromatography with mass spectrometry detection and cavity ring down spectroscopy.

2-Azidomethyl-2-deoxy-3,4-O-isopropylidene-6-O-tert.butyldimethylsilyl-D-talono-1.5-lactone is a synthetic compound that can be customized for your specific needs. It has been shown to have high purity and the ability to undergo a variety of modifications, such as fluorination, glycosylation, methylation, and modification. It is also available in a range of sizes and types of carbohydrate, including saccharides and oligosaccharides.

(Ribo) 3,4-O-Isopropylidene-2,4-di-C-methyl-L-ribono-1.5-lactone is a custom synthesis that can be produced in various quantities and with various modifications to meet your needs. It is a high purity compound that is available for both research and industrial use. This compound has been fluorinated and modified to create a complex carbohydrate. It is an oligosaccharide of polysaccharide that can be used as a monosaccharide or sugar in the synthesis of polysaccharides or saccharides. This product is not intended for medical use.

Methyl 4,6-O-benzylidene-α-D-glucopyranoside is a custom synthesis that can be used in the modification of complex carbohydrates. It is a high purity oligosaccharide with click modification and fluorination. The product is a monosaccharide sugar that has been synthesized by the process of glycosylation and hydrolysis. Methyl 4,6-O-benzylidene-α-D-glucopyranoside also has an Oligosaccharide, Polysaccharide, saccharide, Carbohydrate, Fluorination, complex carbohydrate, High purity, Modification, Monosaccharide, sugar, Synthetic.

Octacetylated chitobiose derivative

<p>CO2-philic compound; used in pharmaceuticals and CO2-based processes</p>

The compound 2S-[2a,3a,4b,5b,6a] -2- (hydroxymethyl)-6-methyl-3,4,5-piperidinetriol is a saccharide with a piperidine ring. It is a synthetic carbohydrate that belongs to the group of oligosaccharides. The fluorine atom in this compound is substituted with methyl groups at positions 2 and 6 on the piperidine ring. This modification is used to increase the water solubility of this carbohydrate. The CAS number for this compound is 53543-33-8.

3-Azido-1-O-t-butyldimethylsilyl-2,3,6-trideoxy-b-L-arabinohexopyranose is a modified sugar. It is used as a building block in the synthesis of oligosaccharides and polysaccharides. This product is custom synthesized to customer's specifications and is available in high purity.

1,2:4,6-Di-O-isopropylidene-L-sorbofuranose is a synthetic carbohydrate with a fluorinated methyl group at the C6 position. It is a monosaccharide that can be used to produce oligosaccharides and saccharides through glycosylation and methylation. The product is available in high purity and custom synthesis. This product has been modified by the click chemistry reaction.

<p>Nonyl b-D-maltopyranoside is a high purity custom synthesis sugar. The CAS number is 106402-05-5 and the molecular weight is 396.2 g/mol. This product has been synthesized using Click modification, Fluorination, Glycosylation, Synthetic, Methylation, Modification, Oligosaccharide, Monosaccharide and saccharide. This product can be used in the preparation of complex carbohydrate.</p>

<p>Rutinose is a naturally occurring polyphenol found in many plants, including the leaves and bark of rue plants. It is a glycoside derivative that has been shown to inhibit human colorectal adenocarcinoma cells (HL-60) by binding to DNA and inhibiting RNA synthesis. Rutinose also has been shown to have anti-inflammatory effects and has been used in the treatment of metabolic disorders such as diabetes mellitus. Rutinose is a bioactive compound with antioxidant properties that may be related to its ability to bind metal ions, including calcium ions at physiological pH levels. Rutinose also has been shown to have a signal peptide sequence that targets it for secretion into the blood stream, where it may act on brain functions.</p>

3,4,6-Tri-O-allyl-D-glucal is a custom synthesis of a complex carbohydrate. It is an Oligosaccharide and Polysaccharide that can be modified by methylation and glycosylation. The product is a Modification of saccharides that has been shown to have Methylation, Glycosylation, Carbohydrate and Click modification. 3,4,6-Tri-O-allyl-D-glucal has CAS No. 434327-45-4 and is available in High purity with Fluorination.

N-Acetyl-D-glucosamine-3-O-sulphate sodium (NADG) is a type of high purity, monosaccharide that is synthesized from D-glucosamine and sulphuric acid. NADG is a synthetic carbohydrate that can be used in the synthesis of complex carbohydrates. It has been modified to contain fluorine atoms at the 3rd and 4th carbon positions. This modification prevents NADG from being hydrolyzed by aminoglycosides such as kanamycin and neomycin, which are used in chemotherapy treatment.

Trehalose is a non-reducing sugar that is naturally found in some plants and animals. It is a disaccharide formed by two glucose molecules linked together with an alpha,alpha glycosidic bond. Trehalose has been shown to inhibit the growth of bacteria through the inhibition of fatty acid biosynthesis and the production of lactic acid. Trehalose has also been shown to have excipients that are used as lubricants or suspending agents in pharmaceuticals, cosmetics, food products, and animal feed. Trehalose can be used as a substitute for propionate in order to create endotoxin-free aqueous solutions.

<p>This is a custom synthesis of a complex carbohydrate. The CAS number is not available and the polysaccharide has been modified. It has been glycosylated, methylated, and fluorinated. It is high purity and the sugar sequence is a custom synthesis.</p>

The device is a leafed, solid-state, responsive device that connects with the user's skin. It measures the user's skin conductance and then produces a signal corresponding to the degree of deliquescence based on a theory that links biophilia to evolutionary circuitry. The device has been shown to be effective in combination with other devices.

Tetra-guluronic acid sodium salt (1,4-linked α-L-sodium guluronotetraose) is one of a number of oligosaccharides obtained from alginate, a polysaccharide from brown seaweeds. It contains blocks of: repeating mannuronic acid sequences (M-M-M-M etc), repeating guluronic acid sequences (G-G-G-G etc), and alternating M-G-M-G sequences. This oligosaccharide can be released by acid hydrolysis and a number of biological activities have been discussed in a recent review.

<p>N-(Succinyl)-O-b-D-galactopyranosylhydroxylamine is a custom synthesis of an oligosaccharide with a modified sugar. The modification includes fluorination and succinylation of the hydroxyl group at the b position on the galactose ring. This sugar is also known as a complex carbohydrate and is found in saccharides, carbohydrates, and sugars. This product is synthesized to provide high purity with a click modification for use in methylation reactions.</p>

1,2,3,4,6-Penta-O-benzoyl-D-mannopyranose is a high purity sugar that is custom synthesized to be used in glycosylation reactions. It has been shown to be effective for Click chemistry and can be fluorinated or methylated. 1,2,3,4,6-Penta-O-benzoyl-D-mannopyranose is a synthetic sugar that can be modified by glycosylation reactions. This sugar has the CAS No. 96996-90-6 and is known as Methyl 1-(1'-methylpropyl)-1H-[1',2',3',4',5',6']pentaoxacyclohexane.

Gypsogenin-3-O-glucuronide is a saponin found in the roots of Gypsophila paniculata, a plant native to China. It has been shown to have anti-inflammatory and anti-tumor activities. Gypsogenin-3-O-glucuronide has been shown to inhibit tumor growth in mice by inhibiting protein synthesis. The pentasaccharides that make up gypsogenin are present in different proportions, which leads to differences in the biological activity of this compound. This is one of the reasons why saponins have not yet been fully explored for potential use in medicine.

<p>1-Cyano-2-deoxy-3,5-di-O-toluoyl-a-D-ribofuranose is a fluorinated monosaccharide that is synthesized by the glycosylation of 1,2:3,4:6,7:8,9-hexahydrobenzo[e]pyrrolo[1,2a]pyrazinone with 2,6:3',5'-dioxo-[1]benzothiophene. This compound has been shown to be an effective inhibitor of the enzyme glycogen synthase kinase 3β (GSK3β) and may have potential as a therapeutic agent for type II diabetes.</p>

Glucosamine sulfate potassium chloride is a reaction solution that contains glucosamine and hydrochloric acid. It is used in the treatment of osteoarthritis and related diseases, as well as for the prevention of cardiovascular disease. Glucosamine sulfate potassium chloride has been shown to reduce pain and improve the clinical response in patients with osteoarthritis. The synergic effect of glucosamine sulfate potassium chloride may be due to its ability to inhibit the degradation of collagen by hydrochloric acid. This drug also increases the production of glycoside derivatives from glucose, which are important for basic protein synthesis. Glucosamine sulfate potassium chloride can be used as a dietary supplement for infants, who have fatty acid deficiencies.

This gamma-cyclodextrin (γ-CD) derivative is a modified cyclic oligosaccharide composed of eight glucose units, featuring a larger cavity size than α- and β-cyclodextrins. This structural characteristic allows γ-CDs to form inclusion complexes with a wider range of guest molecules, making it particularly versatile in various industries. In the food sector, it is used as a carrier and stabilizer for flavors, fat-soluble vitamins, and polyunsaturated fatty acids, protecting volatile compounds from evaporation. In pharmaceuticals, it enhances the solubility and bioavailability of poorly water-soluble drugs and, thanks to its larger ring size, allows for the encapsulation of larger molecules or even entire drug molecules. γ-CDs and derivatives are also used for environmental remediation and, in analytical chemistry, for the extraction and concentration of target substances.

<p>1,6-Anhydro-N,N’-diacetylchitobiose is an anhydrosugar that can be used in the synthesis of oligosaccharides</p>

Bacterial exopolysaccharide from gram negative Flavobacterium spp.

(1S) -1- [(2S, 3R) - 3- Hydroxy- 1- ((4-methoxyphenyl)methyl) - 2- azetidinyl] -1, 2- ethanediol is a synthetic monosaccharide. It can be used in the synthesis of oligosaccharides and glycosylations. Click modification, methylation, and fluorination are all possible modifications for this product. The CAS number for this item is 52634-73-0.

2-C-(tert-Butyldimethylsilyloxy)methyl-2,3:5,6-di-O-isopropylidene-L-gulono-1.4-lactone is a synthetic monosaccharide that is a modification of L-Gulono Oligosaccharide, which is a polysaccharide. 2C-(tert-Butyldimethylsilyloxy)methyl -2,3:5,6-di--O--isopropylidene--L--gulono 1.4 lactone is also known as 2C-(tert butyldimethylsilyloxy) methyl -2,3:5,6--di--O--isopropylidene--L--gulono 1.4 lactone and is used in the manufacture of saccharides and carbohydrates. It can be found in the

Isolated from the products of the acid reversion of D-mannose

3,4-Di-O-acetyl-2,6-di-O-(3,4,6-tri-O-acetyl-2-deoxy-2-phthalimido-b-D-glucopyranosyl)-a-D mannopyranose is a modification of the carbohydrate oligosaccharide. It is a custom synthesis that has high purity and CAS number. The structure of the molecule is an Oligosaccharide with a Carbohydrate. This molecule is an example of a complex carbohydrate. The monosaccharide in this compound is glucose and it has been methylated and glycosylated. This molecule also has a polysaccharide sugar which can be fluorinated or saccharided.

<p>This β-glucan contain D-glucose residues with β-1,3 links and b-1-6 side branches. The frequency, location, and length of the sidechains may play a role in immunomodulation. Differences in molecular weight, shape, and structure of β-glucans can also affect the differences in biological activity. The water-soluble β-D-glucan is extracted from fruiting bodies of Piptoporus betulinus by hot aqueous extraction, followed by freeze-thawing and dialysis. Methylation analysis and NMR spectroscopy, indicated the presence of a β-D-glucan with a main chain (1,3)-linked, substituted at O-6 by single glucose residues.<br>The image was kindly provided by Dr. Chris Lawson.</p>

UDP-a-D-galactose ammonium salt is a nucleotide sugar that is synthesized from uridine and D-galactose. It plays a role in cellular energy metabolism by providing substrate for the synthesis of phospholipids and glycolipids. UDP-a-D-galactose ammonium salt has been shown to be involved in the transcriptional regulation of genes encoding enzymes involved in galactose metabolism. This nucleotide sugar also has been shown to be an exogenous acceptor for various oligosaccharides, including those present on glycoproteins and glycolipids.

<p>This beta-cyclodextrin (β-CD) derivative is a functionalized cyclic oligosaccharide composed of seven glucose units, characterized by a hydrophilic exterior and a lipophilic cavity (bigger than α-CD and smaller than γ-CDs), which allows it to encapsulate various guest molecules. This structural feature facilitates its use in multiple applications, including pharmaceuticals, food enhancement, and cosmetics. In the pharmaceutical industry, it enhances the solubility and stability of poorly water-soluble drugs, improving their bioavailability and efficacy while also masking unpleasant tastes. The food sector utilizes it as a stabilizer for flavors, colors, and nutrients, extending shelf life by protecting sensitive ingredients from degradation. In cosmetics, it serves as a complexing agent for fragrances and active components, ensuring their stability and controlled release. Its use expands to many other fields, including nanotechnology for drug delivery systems, environmental remediation for extracting organic pollutants, textiles for slow-release fragrances, and analytical chemistry for chiral separation.</p>

1,2,3,5,6-Penta-O-benzoyl-D-galactofuranose is a sugar that is custom synthesized and can be modified with fluorination. This product has a CAS number of 138811-45-7 and is high purity. It can be used in glycosylation, oligosaccharide synthesis, methylation, monosaccharide synthesis and polysaccharide synthesis. It is an important building block for the modification of complex carbohydrates.

<p>1,2:4,5-Di-O-cyclohexylidene-b-D-fructopyranose is a modification of the natural carbohydrate 1,2:4,5-di-O-isopropylidene-b-D-fructopyranose. It is an oligosaccharide composed of three units of b-D-fructofuranose linked by α-(1,2) and β-(1,4) glycosidic bonds. The methylation and glycosylation of this saccharide can be customized to produce a wide range of products with different properties. 1,2:4,5 Di O cyclohexylidene b D fructopyranose can be used in applications such as pharmaceuticals and agrochemicals.<br>The molecular formula for this compound is C10H14O8 and its CAS number is 18608-92-9.</p>

Fagomine is a hypoglycemic agent with antimicrobial properties. It is an alpha-mannosidase inhibitor, which prevents the release of glucose from glycogen by inhibiting an enzyme in the glycosylation pathway. The molecular docking analysis shows that fagomine binds to the active site of mitochondrial membrane potential complex I and inhibits its catalytic activity. Fagomine also has a risk of causing metabolic disorders, such as hyperglycemia, hyperinsulinemia, and hyperlipidemia. Studies have shown that fagomine can be used to treat hyperglycemia in both type 1 and type 2 diabetes mellitus patients.