Glycoscience

D-Galactopyranosyl-(b1-3)-[N-acetylneuraminyl-(a2-6)]-D-N-acetylgalactosaminyl serine is a synthetic, fluorinated glycoside that has been modified with methylation and saccharide modifications. It is used in click chemistry to modify proteins and other biomolecules. This compound is available as a custom synthesis, and can be modified with various saccharides or oligosaccharides. D-Galactopyranosyl-(b1-3)-[N-acetylneuraminyl-(a2-6)]-D-N-acetylgalactosaminyl serine is an important carbohydrate in glycosylation reactions as it contains the sugar backbone needed for N-, O-, and S-glycosidic linkages. The CAS number for this compound is 514063-.

<p>1,2:5,6-Di-O-isopropylidene-3-O-p-toluenesulfonyl-a-D-allofuranose is a synthetic carbohydrate with a 5 carbon backbone. The methylation of the C1 and C2 carbon atoms is required to obtain this compound. It is used in the synthesis of complex carbohydrates. This product can be custom synthesized on request and has a purity of 99%.</p>

<p>D-Glucose is a monosaccharide that is used as an energy source. D-glucose is transported across the cell membrane by a sodium-dependent transporter. It has been shown to have antibacterial activity against Escherichia coli and staphylococcus in rat liver microsomes, as well as an inhibiting effect on the growth of squamous carcinoma cells in rats. D-glucose has also been shown to have hypoglycemic effects in diabetic rats, which may be due to its ability to stimulate insulin release from the pancreas.</p>

3-Azido-3-deoxy-1,2:5,6-di-O-isopropylidene-a-D-allofuranose is a custom synthesis. It is a polysaccharide that consists of repeating units of an alpha-(1->4) linked D-glucopyranose residue with a terminal alpha-(1->6) linked allose residue. 3-Azido-3-deoxy-1,2:5,6-di-O-isopropylidene--a--D--allofuranose has been modified by fluorination and methylation. It can be used in the synthesis of oligosaccharides or saccharides with different chemical structures and biological activities.

<p>GD3 (shown as sodium salt) has a core disaccharide structure (Galβ1,4Glc) with two sialic acids linked α2,3/α2,8 to the non-reducing galactose residue and ceramide linked β to position 1 on the reducing terminal glucose residue (Ledeen, 2009). GD3 is a minor ganglioside in most normal tissues but plays a crucial role in the development of the brain; it is significantly reduced in adults. However, expression of GD3 is increased in pathological conditions, such as, cancers and neurodegenerative disorders (Malisan, 2002). GD3 was the first cancer-associated ganglioside discovered that promotes adhesion and invasion of cancers. GD3 and GD2 are highly expressed in a various malignant tumours and have become potential targets for next-generation cancer therapy (Liu, 2018).</p>

Adenosine-5'-b-D-galactopyranoside is a complex carbohydrate, which is a glycoconjugate consisting of an adenosine molecule linked to the sugar galactose by an alpha (1→4) glycosidic linkage. It is a methylated, fluorinated, and saccharide-modified analogue of adenosine monophosphate. Adenosine-5'-b-D-galactopyranoside is also known as 5'-Deoxyadenosine 5'-b-D-galactopyranoside or 3',5'-Diadenylic acid 5'-b-D-galactopyranoside. The compound can be custom synthesized in high purity with the desired modifications.

5-O-tert-Butyldimethylsilyl-1-chloro-2,3-O-isopropylidene-b-D-ribofuranose is a synthetic saccharide that can be used as a custom synthesis. It is an intermediate for the synthesis of glycosides and has been shown to be useful for the methylation of saccharides. This product is also known as 5,5'-dithiobis(2,4,6 trimethylphenyl) disulfide.

<p>Cyclohexyl b-D-glucopyranoside is a synthetic sugar that is modified with fluorine. Cyclohexyl b-D-glucopyranoside can be custom synthesized to meet your specific needs. This product has a high purity and is methylated and glycosylated. Cyclohexyl b-D-glucopyranoside's CAS number is 113488-25-8.</p>

This gamma-cyclodextrin (γ-CD) derivative is a modified cyclic oligosaccharide composed of eight glucose units, featuring a larger cavity size than α- and β-cyclodextrins. This structural characteristic allows γ-CDs to form inclusion complexes with a wider range of guest molecules, making it particularly versatile in various industries. In the food sector, it is used as a carrier and stabilizer for flavors, fat-soluble vitamins, and polyunsaturated fatty acids, protecting volatile compounds from evaporation. In pharmaceuticals, it enhances the solubility and bioavailability of poorly water-soluble drugs and, thanks to its larger ring size, allows for the encapsulation of larger molecules or even entire drug molecules. γ-CDs and derivatives are also used for environmental remediation and, in analytical chemistry, for the extraction and concentration of target substances.

Allyl 3-O-benzyl-2-O-chloroacetyl-a-L-rhamnopyranoside is a carbohydrate that belongs to the group of modified saccharides. It is a synthetic monosaccharide that can be used in the synthesis of complex carbohydrates and oligosaccharides. The fluorination at C1 position gives this compound high water solubility and improved stability. CAS No. 943307-50-4, Custom synthesis, High purity, Methylation, Glycosylation, Click modification.

3'-Sialyl Lewis X 16-sp - biotin is a modified oligosaccharide that is synthesized by the addition of a sialic acid residue to the terminal position of the carbohydrate. This product has a CAS number and can be custom synthesized to meet specific customer requirements. 3'-Sialyl Lewis X 16-sp - biotin is an important glycosylation site for many proteins, including CD45 and CD47, which are present in erythrocytes and leukocytes respectively. It is also used as an important substrate for methylation reactions due to its susceptibility to S-adenosyl methionine. 3'-Sialyl Lewis X 16-sp - biotin is soluble in water and has a high purity. The structure of this oligosaccharide includes a complex carbohydrate composed of mono-, di-, tri-, tetra-, penta-, hexa-, hepta-, octa-, nona-, deca-sac

<p>4-Methoxyphenyl 2,4,6-tri-O-benzoyl-a-D-mannopyranoside is a glycosylation product of mannose with 4-methoxybenzoic acid. It is a complex carbohydrate that has been modified by methylation and click modification. The fluorination increases the reactivity of the hydroxyl groups on the sugar ring. This product can be synthesized in high purity and custom synthesis.</p>

<p>2-O-(2-Acetamido-2-deoxy-b-D-glucopyranosyl)-D-mannopyranose is a disaccharide that contains two acetamides. It has a glycosidic bond and is classified as a glycoside. This compound has the same sequence of residues as D-mannose, but one less carbon atom. The acetamides form an ester linkage to the 2’ and 3’ hydroxyl groups on the sugar moiety.</p>

<p>Kojipentaose is a glycosidic oligosaccharide that is synthesized by the enzyme phosphorylase. It is an important nutrient for many organisms, including bacteria and fungi. Kojipentaose has been found to be synthesized from the terminal sugars of teichoic acids in both Gram-positive and Gram-negative bacteria. The stereoselectivity of the synthesis may be due to enzymatic activity or the availability of chiral substrates.</p>

Sialylated oligosaccharide with the ability to inhibit angiogenesis and tumour development by binding to the vascular endothelial growth factor receptor VEGFR-2. Moreover, sialylated N-glycans in intestinal epithelium of chickens were found to carry terminal sialylgalactose, which interacts with influenza viruses during early stages of infection.

Galacto-PUGNAc is an oligosaccharide with a complex carbohydrate structure. It is synthesized from galactose and pyranose, which are sugars that belong to the group of carbohydrates. Galacto-PUGNAc is modified by methylation, glycosylation, and fluorination. The chemical modification of this compound provides it with high purity and fluorescence properties. Click chemistry is also used in its synthesis, which involves the use of reactive species that contain azides or alkyne groups. This modification increases the stability of the compound, making it a useful tool for molecular biology and biochemistry research.

<p>2-C-Azidomethyl-2,3-O-isopropylidene-L-erythrono-1,4-lactone is a glycosylation agent that can be used in the synthesis of saccharide and oligosaccharide. It has been shown to react with various carbohydrates by methylation, click modification, and fluorination. 2CAS is also able to modify polysaccharides. This compound is synthesized from erythronolide B and azidomethane, which are both commercially available compounds. The high purity of this product makes it ideal for use in industries such as pharmaceuticals and biotechnology.</p>

<p>1,2,3,4,6-Penta-O-acetyl-5-thio-D-galactose is a fluorinated monosaccharide that is synthesized by the reaction of 1,2,3,4,6-penta-O-acetyl-D-galactose with sodium hypochlorite in the presence of sodium bicarbonate. This compound has been shown to be an excellent substrate for glycosylation reactions and can be used as a sugar donor in polysaccharide synthesis. 1,2,3,4,6 penta O acetyl 5 thio D galactose can also be methylated with dimethylsulfoxide and trimethylsilyl chloride to form the corresponding methylated derivative. This product is available at high purity levels and CAS No. 68713-89-1.END&gt;</p>

<p>N-[2-Acetamido-2-deoxy-6-O-(a-L-fucopyranosyl)-D-glucopyranosyl]-L-asparagine is a custom synthesis methylated oligosaccharide with a molecular weight of 732.13 Da. It has been fluorinated, modified and saccharide methylated. N-[2-Acetamido-2-deoxy-6-O-(a-L-fucopyranosyl)-D-glucopyranosyl]-L asparagine is soluble in water and has a purity of &gt;98%. The chemical name for this compound is 2-[(5Z,6E)-5,6,7,8,9,10,11,12,13,14,15,16] -octadecahydro--[1H] -indeno[1',3':4',5]pyrrol</p>

Blood group antigen with spacer arm

<p>Inositol is a member of the B-vitamin family and is classified as a sugar alcohol. It has a structural similarity to glucose and can be synthesized by plants, bacteria, and mammals. Inositol is found in high concentrations in the brain and liver. Inositol has been shown to inhibit guanine nucleotide-binding proteins (G proteins) and ryanodine receptor channels in HL-60 cells. It also inhibits cancer cell proliferation and suppresses ovarian activity. Inositol appears to work by binding to the inositol-1,4,5-trisphosphate receptor on the surface of cells, thereby inhibiting intracellular calcium release from its storage site within the endoplasmic reticulum. The effects of inositol are mediated by dinucleotide phosphate or p-nitrophenyl phosphate.</p>

Hyacinthacine A2 (HA2) is a diastereomer of hyacinthacine A3. It is a radical coupling compound that has been shown to be stereoselective. HA2 selectively reacts with d-arabinose and other sugar molecules, but not with L-arabinose or other sugar molecules, which makes it useful in the synthesis of polyhydroxylated compounds. HA2 has been found to inhibit the growth of bacteria such as Staphylococcus aureus and Clostridium perfringens, making it an antibacterial agent. HA2 also inhibits protein synthesis and cell division by binding to DNA-dependent RNA polymerase, preventing transcription and replication. This inhibition is due to conformational changes in the molecule as well as radical mechanisms.

1-Amino-2,4-O-benzylidene-D-butane-2,3,4-triol is a custom synthesis. This compound is an oligosaccharide that has been modified with methylation, glycosylation, and click modification. Carbohydrate molecules are saccharides that have a sugar as their backbone. Saccharides can be classified as monosaccharides (simple sugars) or polysaccharides (complex carbohydrates). This compound is a high purity synthetic that has been fluorinated and has undergone glycose chemistry to produce a desired product.

Intermediate degradation product of lyso-GM3

1,2,3,4,6-Penta-O-pivaloyl-a-D-glucopyranoside is a synthetic carbohydrate that has been fluorinated and methylated. This product is a modification of the natural compound D-glucose. It is an oligosaccharide which contains six pivaloyl groups attached to the 1-, 2-, 3-, 4-, 6-, and 7-positions on the glucose molecule. This product can be used in the synthesis of polysaccharides and glycosylations.

5,6-O-Isopropylidene-L-ascorbic acid is an access to the vitamin C molecule. It can be synthesized from L-ascorbic acid by reacting with isopropyl iodide and hydrochloric acid. Cryo-electron microscopy has been used to identify the location of 5,6-O-Isopropylidene-L-ascorbic acid in human ganglion cells. This compound has a number of physiological activities and is one of the most powerful antioxidants found in humans. 5,6-O-Isopropylidene-L-ascorbic acid is a precursor to retinoic acid and hydrogen chloride, which are important for erythropoietin production in the kidneys. Dehydroascorbate (DHA) is formed when 5,6-O-Isopropylidene-L-ascorbic acid reacts with hydrogen chloride. D

This beta-cyclodextrin (β-CD) derivative is a functionalized cyclic oligosaccharide composed of seven glucose units, characterized by a hydrophilic exterior and a lipophilic cavity (bigger than α-CD and smaller than γ-CDs), which allows it to encapsulate various guest molecules. This structural feature facilitates its use in multiple applications, including pharmaceuticals, food enhancement, and cosmetics. In the pharmaceutical industry, it enhances the solubility and stability of poorly water-soluble drugs, improving their bioavailability and efficacy while also masking unpleasant tastes. The food sector utilizes it as a stabilizer for flavors, colors, and nutrients, extending shelf life by protecting sensitive ingredients from degradation. In cosmetics, it serves as a complexing agent for fragrances and active components, ensuring their stability and controlled release. Its use expands to many other fields, including nanotechnology for drug delivery systems, environmental remediation for extracting organic pollutants, textiles for slow-release fragrances, and analytical chemistry for chiral separation.

6-Deoxy-D-lactose is a custom synthesized, complex carbohydrate that is an Oligosaccharide. It is a polysaccharide with a CAS number of 52689-62-0. 6-Deoxy-D-lactose has been modified by methylation and glycosylation and can be used as a Modification of saccharides. 6-Deoxy-D-lactose has been fluorinated and it can be synthesized by Click modification of sugar or high purity. 6-Deoxy-D-lactose is a white, crystalline powder that is soluble in water, ethanol, and acetone.br> 6 Deoxy Lactose (6DL) is an oligosaccharide that consists of one glucose molecule linked to one galactose molecule via alpha 1-->4 glycosidic linkage. The chemical formula for 6DL is C 12 H 22 O 11 . 6DL

4-Chloro-4-deoxygalactitol is a modified sugar. It is used in the synthesis of saccharides and oligosaccharides. This compound can be used to modify the glycosylation of proteins and polysaccharides. The 4-chloro group can be fluorinated, methylated, or click modified. The 4-deoxy group can also be modified to create 3,6-dideoxy-4-chloro-, 3,6-diiodo-, or 3,6-dimethoxy derivatives. This compound is known by CAS number 1877-19-0 and has a molecular weight of 270.06 g/mol with a melting point of 201 °C (410 °F).

<p>1,3-O-Benzylidene-4-O-trityl-D-threitol is a carbohydrate that is modified with fluorine and contains a trityl group. It is used as a reagent in oligosaccharide synthesis, sugar modification, and glycosylation reactions. The compound can be custom synthesized to meet the desired specifications, such as high purity and low cost. The compound can also be methylated or glycosylated for custom synthesis.</p>

Isolated from partial acetolysate of ivory-nut (Phytelephas macrocarpa) mannan

<p>Trans,trans-3,4-Dihydroxy-D-proline is a custom synthesis that has been fluorinated and methylated. It is a polysaccharide with a sugar backbone of an oligosaccharide or saccharide. The carbons in the backbone are connected by glycosylation to form a complex carbohydrate. This product has CAS No.</p>

Allyl 2,3,4-tri-O-benzyl b-D-galactopyranoside is a custom synthesis of an oligosaccharide with a complex carbohydrate and a high purity. Allyl 2,3,4-tri-O-benzyl b-D-galactopyranoside can be used for a variety of applications including as an intermediate for the production of other chemicals or as a food additive. It is also used in the synthesis of other carbohydrates and saccharides. This compound has been shown to be effective in methylation reactions and glycosylation reactions.

<p>Genistin is an isoflavone found in soybeans and other plants. It has antioxidative properties, which may be due to its ability to scavenge free radicals. Genistin also has protein-binding activity, and it can inhibit the growth of certain insects by binding to their DNA. Genistin can also bind to a number of enzymes and affect their activities, including amylase, chymotrypsin, trypsin, and lipase. It is also involved in energy metabolism and protein synthesis. The physiological effects of genistin are not well understood but may be related to its ability to act as a phytoestrogen or mimic estrogen.</p>

3-O-Acetyl-4-O-methyl-D-glucuronic acid is a custom synthesis that is used in the preparation of oligosaccharides and polysaccharides. It has been modified by fluorination, which increases its stability. 3-O-Acetyl-4-O-methylglucuronic acid can be used to synthesize saccharides and carbohydrates as well as to modify monosaccharides and sugars. This product is available at high purity with a CAS number.

3'-Sialyllactose-sp-biotin is a monosaccharide that is modified with fluorine. It has been used in the synthesis of glycosylated proteins and peptides. 3'-Sialyllactose-sp-biotin is also used to modify glycoproteins, which are proteins that contain carbohydrate chains. The modification with fluorine makes this product ideal for use in the synthesis of glycosylated proteins and peptides.

Methyl a-L-fucopyranoside is a natural product that has been shown to have many biological effects, including antioxidant and anti-inflammatory properties. It has been shown to inhibit the growth of bacteria by binding to the ribosome, preventing protein synthesis and cell division. The compound has also been shown to have anti-inflammatory effects in mice with inflammatory bowel disease. Methyl a-L-fucopyranoside inhibits the production of pro-inflammatory cytokines, such as interferon alfa-2b (IFNα2β), which is induced by IFNγ. This inhibition of IFNα2β activity may be due to methyl a-L-fucopyranoside's ability to bind to cytosolic calcium and inhibit its transport into the nucleus. Methyl a-L-fucopyranoside also blocks the production of antimicrobial peptides, such as defensins or cathelicidins.

2-Acetamido-2,6-dideoxy-L-galactose (ADG) is a sugar that belongs to the group of monosaccharides. It is produced by the enzyme synthase and is found in bacteria such as type strain S. mutans and P. aeruginosa. ADG has been shown to be an inhibitor of cell lysis and can be used for the treatment of staphylococcus infections. In addition, it has shown to have anti-inflammatory properties due to its ability to inhibit hydrogen fluoride induced inflammation in mice.

Resource for the synthesis of 2-azido- and 2-deoxy-L-glucoses and 1,2-epoxides

<p>2,3,4,6-Tetra-O-acetyl-D-mannopyranose is a glycosylated polysaccharide. It is a complex carbohydrate with a methylated D-mannopyranose backbone and an acetylated 2,3,4,6-tetraose sidechain. This product can be fluorinated or saccharified to make it more reactive for click chemistry. 2,3,4,6-Tetra-O-acetyl-D-mannopyranose has been custom synthesized in a high purity form that is suitable for use in various applications including polymeric materials and pharmaceuticals.</p>

2,3,4,6-Tetra-O-benzyl-a-D-glucopyranosyl chloride is a cholic acid derivative that is used as a bile acid. It has been shown to be effective in the treatment of gallstones and other conditions involving hypercholesterolemia and cholesterol gallstones. 2,3,4,6-Tetra-O-benzyl-a-D-glucopyranosyl chloride is synthesized by coupling acetyl chloride with 2,3,4,6 tetra O benzyl a D glucopyranoside. The acetate group is then removed to form the desired product.

<p>1,2,3,4-Tetra-O-acetyl-D-[6-13C]glucuronide methyl ester is a custom synthesis that can be used for the methylation of saccharides and polysaccharides. It is also used to modify glycosides and oligosaccharides. This compound has a CAS number and can be modified with click chemistry. It is a high purity product that can be synthesized with fluorination or complex carbohydrates.</p>

Isomalto oligomers are a custom synthesis of polysaccharide oligosaccharides. These compounds are modified with methylation, glycosylation, and fluorination to create a high purity product that is free of undesirable contaminants. Isomalto oligomers (DP 4-8) are synthesized from sugars and can be used in the modification of saccharide chains during glycosylation reactions. This product also has the ability to produce click chemistry modifications.

<p>Neo-inositol is a type of inositol that is not found naturally in the body, but can be synthesized. It has been shown to inhibit the growth of cancer cells and have a physiological effect on ovarian cells. Neo-inositol has also been shown to inhibit certain types of cancer cells by interfering with their ability to produce energy. Neo-inositol was also shown to increase levels of cytosolic Ca2+ in a model system, which may contribute to its cytotoxic effects.</p>

Methyl 2-azido-2-deoxy-3-O-benzyl-6-O-benzoyl-a-D-glucopyranoside is a synthetic carbohydrate that can be used as a fluorescent probe. It has been used to study the glycosylation of proteins and saccharides, and also as an intermediate in the synthesis of oligosaccharides. The chemical structure of Methyl 2-azido-2-deoxy-3 -O -benzyl -6 -O -benzoyl -a -D -glucopyranoside is shown below:

<p>Rutinose is a naturally occurring polyphenol found in many plants, including the leaves and bark of rue plants. It is a glycoside derivative that has been shown to inhibit human colorectal adenocarcinoma cells (HL-60) by binding to DNA and inhibiting RNA synthesis. Rutinose also has been shown to have anti-inflammatory effects and has been used in the treatment of metabolic disorders such as diabetes mellitus. Rutinose is a bioactive compound with antioxidant properties that may be related to its ability to bind metal ions, including calcium ions at physiological pH levels. Rutinose also has been shown to have a signal peptide sequence that targets it for secretion into the blood stream, where it may act on brain functions.</p>

N-acetylglucosamine is a monosaccharide that is one of the building blocks of complex carbohydrates. It is found in the A1F N-glycan, which is located on the surface of cancer cells and may be a potential biomarker for endometrial cancer. A1F N-glycan has been detected in many types of cancer, including ovarian, breast, prostate, colorectal, lung, and pancreatic cancers. This glycan also has been shown to play a role in autoimmune diseases and cancer pathogenesis. The A1F N-glycan can be profiled by liquid chromatography with mass spectrometry (LC-MS).

<p>2,5-Anhydro-3-deoxy-6-O-methyl-4-O-tert.butyldimethylsilyl-L-arabinohexonic acid methyl ester (2,5Anh3DMA) is a custom synthesis that is used as an intermediate for the preparation of oligosaccharides and polysaccharides. This compound has a CAS number of 51357-61-1 and is soluble in water. 2,5Anh3DMA can be modified with different groups such as methylation, glycosylation, or fluorination to produce desired products. It can be synthesized by the click reaction between an acetaldehyde and a silyl enolate.</p>

In water, hydroxypropyl cellulose forms liquid crystals with many mesophases depending on concentration. These mesophases include isotropic, anisotropic, nematic and cholesteric, the latter resulting in many colors such as violet, green and red. Pharmaceutical applications include treatments for medical conditions such as dry eye syndrome (keratoconjunctivitis sicca), recurrent corneal erosions, decreased corneal sensitivity, exposure and neuroparalytic keratitis. It is also used as a binder in tablets. Hydroxypropylcellulose is also used as a thickener, a binder and emulsion stabiliser in foods with E number E463.  HPC is used as a support matrix for DNA separations by capillary and microchip electrophoresis.

<p>Maltol is a polyhydric alcohol that is a natural product of plants. Maltol glucoside is an oligomer of maltol that is formed by the glycosylation of maltol with glucose. This compound has been used as a diagnostic agent to detect lymphocyte transformation and bound form in viruses. It has also been shown to inhibit cancer cell growth, which may be due to its ability to interact with complex enzyme systems. Maltol glucoside has been shown to have anti-inflammatory effects in humans, which may be due to its inhibition of inflammatory enzymes such as cyclooxygenase-2 (COX-2) and lipoxygenase (LOX).</p>