Antifúngicos
Los antifúngicos son compuestos específicamente diseñados para detener, prevenir y eliminar el crecimiento de hongos. En esta categoría, encontrará una amplia variedad de agentes antifúngicos esenciales para aplicaciones de investigación y terapéuticas. Estos compuestos son cruciales en el tratamiento de infecciones fúngicas y en la prevención de su recurrencia, lo que los convierte en herramientas vitales tanto en entornos médicos como agrícolas. Investigadores y profesionales de la salud pueden explorar numerosos antifúngicos para comprender sus mecanismos, optimizar su eficacia y desarrollar nuevos tratamientos para combatir cepas de hongos resistentes. La extensa selección de antifúngicos respalda los avances continuos en la investigación fúngica y el desarrollo de terapias antifúngicas efectivas.
Se han encontrado 837 productos de "Antifúngicos"
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Chitin synthase inhibitor 5
<p>Calpain Inhibitor-2, lipophilic, inhibits calpain; shows anti-proliferative effects on melanoma, PC-3 cells; blocks 80% DU-145 cell invasion.</p>Fórmula:C23H22BrN3O5Forma y color:SolidPeso molecular:500.34CDA-IN-4
CAS:<p>CDA-IN-4 (compound VS-24) is an inhibitor of chitin deacetylase (CDA). At a concentration of 100 μg/mL, CDA-IN-4 provides a protective effect of 61.2% against rice blast disease.</p>Fórmula:C10H9BrN4O2SForma y color:SolidPeso molecular:329.17PKR-IN-1
CAS:<p>PKR-IN-1 (Compound 5s) is a pyruvate kinase (PK) inhibitor with antifungal properties, exhibiting an EC50 of 0.21 μg/mL against Rhizoctonia solani (R. solani).</p>Fórmula:C9HCl5N4OS2Forma y color:SolidPeso molecular:422.525Antifungal agent 12
<p>Antifungal agent 12 is a new fluconazole-like compound that exhibits good antifungal effects.</p>Fórmula:C20H16F3N7O2S2Forma y color:SolidPeso molecular:507.51N'-(2-Fluorophenyl)pyrazine-2-carbohydrazide
<p>N'-(2-Fluorophenyl)pyrazine-2-carbohydrazide is a Ole1p desaturase inhibitor as well as antifungal agent [1].</p>Fórmula:C11H9FN4OForma y color:SolidPeso molecular:232.21Antifungal agent 19
<p>Antifungal agent 19 shows the potent antifungal activity ( EC 50 = 0.72 μM).</p>Fórmula:C19H18F4O2Forma y color:SolidPeso molecular:354.34Antifungal agent 11
<p>Antifungal agent 11 has a good antifungal effect.</p>Fórmula:C21H19F2N7O3S2Forma y color:SolidPeso molecular:519.55CDA-IN-2
CAS:<p>CDA-IN-2 (Compound VS#2-3) is an inhibitor of chitin deacetylase (CDA) that exhibits antifungal properties. At a concentration of 100 μM, it inhibits P. xanthii's CDAPxCDA1 by 83.7% and PxCDA2 by 74.5%. CDA-IN-2 is applicable in research on agricultural fungal diseases, including resistance to powdery mildew and gray mold.</p>Fórmula:C17H16N2O7Forma y color:SolidPeso molecular:360.318bc1 Complex-IN-1
CAS:<p>Bc1 Complex-IN-1 (compound 12g) is a potent inhibitor of the bc1 complex, demonstrating fungicidal properties against cucumber downy mildew (CDM).</p>Fórmula:C16H22N6O5S2Forma y color:SolidPeso molecular:442.513WQ3810 TFA
<p>WQ3810 TFA is an orally available fluoroquinolone with antimicrobial activity against Mycobacterium tuberculosis and inhibits the DNA rotamase activity of</p>Fórmula:C24H23F6N5O5Pureza:99.52%Forma y color:SoildPeso molecular:575.46Antifungal agent 42
<p>Antifungal 42 blocks biofilm formation and inhibits C.albicans' CYP51.</p>Fórmula:C22H20Cl2N4Se2Forma y color:SolidPeso molecular:569.25Hyalodendrin
CAS:<p>Hyalodendrin ((+)-Hyalodendrin) acts as a fungal growth inhibitor, specifically targeting wood decay fungi. It exhibits low phytotoxicity and possesses an acute toxicity (LD50) level of 75 mg/kg in mice.</p>Fórmula:C14H16N2O3S2Forma y color:SolidPeso molecular:324.42Antifungal agent 125
CAS:<p>Antifungalagent 125 (compound 4H) is a potent succinate dehydrogenase (SDH) inhibitor with an IC50 of 3.59 μg/mL and exhibits fungicidal activity against Alternaria alternata.</p>Fórmula:C13H10BrNO4SForma y color:SolidPeso molecular:356.192Antifungal agent 127
CAS:<p>Antifungalagent 127 (Compound 6c) is an antifungal agent with potent inhibitory activity against Botrytis cinerea and Rhizoctonia solani.</p>Fórmula:C13H12ClN3OForma y color:SolidPeso molecular:261.707Chitin synthase inhibitor 6
<p>Compound 9b inhibits CHS with an IC50 of 0.21 mM; it's a broad-spectrum antifungal, effective against resistant strains.</p>Fórmula:C24H25N3O6Forma y color:SolidPeso molecular:451.47Antifungal agent 25
<p>Antifungal agent 25: broad-spectrum, stable in vivo, effective against Candida albicans, including fluconazole-resistant strains.</p>Forma y color:SolidAntifungal agent 16
<p>Antifungal agent 16 has antimicrobial activity comparable to that of ciprofloxacin and has higher antifungal activity than fluconazole.</p>Fórmula:C27H21N5O2SForma y color:SolidPeso molecular:479.55CDA-IN-1
CAS:<p>CDA-IN-1 (Compound vs#2-1) is an inhibitor of chitin deacetylase (CDA) that exhibits antifungal activity. By inhibiting fungal CDA activity, it activates plant immune responses and leads to the accumulation of reactive oxygen species (ROS), hindering fungal growth. At a concentration of 100 μM, CDA-IN-1 achieves inhibition rates of 86.9% on P. xanthii's PxCDA1 and 74.5% on PxCDA2. CDA-IN-1 is applicable in research on fungal plant diseases, such as cucumber powdery mildew and tomato gray mold.</p>Fórmula:C15H14N2O6Forma y color:SolidPeso molecular:318.281Succinate dehydrogenase-IN-8
CAS:<p>Succinate dehydrogenase-IN-8 (compound i19) is a potent inhibitor of succinate dehydrogenase (SDH). This indanoyl amino acid derivative demonstrates strong antifungal activity in vitro against Rhizoctonia solani (EC50 = 0.1843 mg/L), Botrytis cinerea (EC50 = 0.4829 mg/L), and Sclerotinia sclerotiorum (EC50 = 0.1349 mg/L).</p>Fórmula:C22H19Cl2F2N5O2Forma y color:SolidPeso molecular:494.32HDAC-IN-87
CAS:<p>HDAC-IN-87 (Compound XII6) is a non-selective HDAC inhibitor with pIC50 values of 6.9 for HDAC4 and 5.8 for HDAC6. It exhibits fungicidal activity against P. sorghi and P. pachyrhizi. The acute oral LD50 in both male and female rats is greater than 500 mg/kg.</p>Fórmula:C13H7F5N4O2SForma y color:SolidPeso molecular:378.277Tenellin
CAS:<p>Tenellin is a fungal metabolite that inhibits Mg2+-, Ca2+-, and Na+/K+-ATPase activities in erythrocytes. Tenellin is cytotoxic to Sf9 and Sf21 insect cells.</p>Fórmula:C21H23NO5Forma y color:SolidPeso molecular:369.41Ethaboxam
CAS:<p>Ethaboxam is a β-tubulin inhibitor and antifungal agent used against oomycete pathogens.</p>Fórmula:C14H16N4OS2Pureza:99.37%Forma y color:SolidPeso molecular:320.43Nikkomycin Z
CAS:<p>Nikkomycin Z (Nikkomycin Z from Streptomyces tendae) is a competitive chitin synthase inhibitor.It inhibitor of the growth of filamentous fungi, insects,</p>Fórmula:C20H25N5O10Pureza:98%Forma y color:SolidPeso molecular:495.44Antifungal agent 39
CAS:<p>Antifungal agent 39 (Compound 9h) is a broad-spectrum antifungal agent.</p>Fórmula:C23H22ClN3O5Forma y color:SolidPeso molecular:455.89Yck2-IN-1
CAS:<p>Yck2-IN-1 (Compound 2a) is an inhibitor of the fungus Candida albicans Yck2. It has an IC50 of approximately 80 nM for Yck2 and an MIC80 of 12.5 µM for C. albicans, demonstrating good metabolic stability [66% remaining in mouse liver microsomes]. In a mouse model with drug-resistant Candida, Yck2-IN-1 significantly reduced fungal load in the kidneys. Yck2-IN-1 shows potential for research in antifungal infection treatments.</p>Fórmula:C19H11FN4Forma y color:SolidPeso molecular:314.316Fosmanogepix
CAS:<p>Fosmanogepix (APX001) is a broad-spectrum oral antifungal that targets Gwt1 enzyme, transforming into active APX001A in the body.</p>Fórmula:C22H21N4O6PPureza:98%Forma y color:SolidPeso molecular:468.40Chitin synthase inhibitor 7
<p>Compound 9c, a chitin synthase inhibitor, has an IC50 of 0.37 nM and is useful for studying fungal infections.</p>Fórmula:C24H25N3O5Forma y color:SolidPeso molecular:435.47ATPase-IN-5
CAS:<p>ATPase-IN-5 (Compound 11) is an antifungal Pma1p (H+ -ATPase) inhibitor (IC50 = 12.7 μM) that inhibits the growth of Candida albicans and Saccharomyces cerevisiae.</p>Fórmula:C10H10N4O3SPureza:99.19%Forma y color:SolidPeso molecular:266.28Antifungal agent 100
CAS:<p>Antifungal agent 100 (compound 3i) demonstrates notable antifungal activity, exhibiting an EC 50 of 0.33 mg/L against S. sclerotiorum. It also possesses an IC 50 value of 0.63 mg/mL targeting the Succinate dehydrogenase (SDH) of the same organism [1].</p>Fórmula:C23H21N3O4SForma y color:SolidPeso molecular:435.5Wikstrol A
CAS:<p>Wikstrol A: antifungal, anti-mitotic, anti-HIV agent with various IC50/MDC values (67.8-131 µM) and deforms P. oryzae mycelia.</p>Fórmula:C30H22O10Forma y color:SolidPeso molecular:542.49Chitin synthase inhibitor 12
<p>Chitin synthase inhibitor 12: potent CHS blocker (IC50: 0.16 mM), broad-spectrum antifungal, effective against resistant strains. Useful in IFI research.</p>Fórmula:C23H21ClFN3O5Forma y color:SolidPeso molecular:473.88Chitin synthase inhibitor 9
<p>CHS inhibitor 9: a broad-spectrum antifungal for studying fungal infections.</p>Fórmula:C24H25N3O6Forma y color:SolidPeso molecular:451.47D75-4590
CAS:<p>D75-4590, a β-1,6-Glucan synthetase inhibitor, combats fungal infections by targeting cell walls.</p>Fórmula:C21H27N5Pureza:98.56% - 98.85%Forma y color:SolidPeso molecular:349.474-Hydroxyvoriconazole
CAS:<p>Metabolite of voriconazole; sterol 14?-demethylase inhibitor</p>Pureza:Min. 95%(S,S)-Valifenalate
CAS:<p>(S,S)-Valifenalate is an acylamino acid fungicide and is used to control a wide range of fungi belonging to the class of Oomycetes.</p>Fórmula:C19H27ClN2O5Forma y color:SolidPeso molecular:398.88Rhizocticin A
CAS:<p>Rhizocticin A is a potential inhibitor of threonine synthase.</p>Fórmula:C11H22N5O6PPureza:98%Forma y color:SolidPeso molecular:351.3Tetraconazole
CAS:<p>Tetraconazole is an agent of pesticides.</p>Fórmula:C13H11Cl2F4N3OForma y color:Liquid ViscousPeso molecular:372.14
