Antimicrobianos

STAADIUM™ PeptiZide L-Ala is a targeted inhibitor for L-alanine aminopeptidase-producing bacteria. The antibacterial activity of STAADIUM™ PeptiZide L-Ala is triggered by the enzyme L-alanine aminopeptidase, an enzyme located in the bacterial cell wall and is a characteristic of Gram-negative bacteria. L-alanine aminopeptidase has not been experimentally detected in Campylobacter species, anaerobic bacilli, Gram-positive and Gram-variable bacteria. More details in the application notes document.

Filociclovir is a novel antiviral agent, which is synthesized from small-molecule pharmaceutical compounds. It functions primarily by inhibiting viral DNA polymerase, thereby halting viral replication within infected host cells. This mechanism of action is particularly effective against certain herpesviruses, as it targets the polymerase enzyme that is critical for viral DNA synthesis and proliferation.

A thiopeptide antibiotic produced by the bacterium Streptomyces actuosus. In addition, nosiheptide inhibits bacterial protein biosynthesis by acting during the elongation of the protein.

Remdesivir (R)-isomer is a nucleoside analog antiviral with action on RNA-dependent RNA polymerase to inhibit viral replication and is used for treating COVID-19 and other RNA virus infections.

Aminoglycoside antibiotic; inhibits protein synthesis by inducing miscoding

Tomopenem is a carbapenem antibiotic, which is a product of synthetic origin with broad-spectrum antibacterial properties. It acts by inhibiting the synthesis of bacterial cell walls through binding to penicillin-binding proteins, thereby disrupting the structural integrity of the cell wall and leading to bacterial cell lysis and death.