Ácidos grasos

Ascorbyl palmitate is an ester of ascorbic acid and palmitic acid. It is a water-soluble antioxidant that has been shown to be safe for oral ingestion at doses of up to 3 grams per day. Ascorbyl palmitate is used in topical formulations to provide protection against sun damage, and also has been shown to have anti-inflammatory properties, which may be due to its inhibitory effect on the mcl-1 protein. Ascorbyl palmitate has a phase transition temperature at about 41°C. This compound can be used in pharmaceuticals for the treatment of infectious diseases caused by bacteria such as tuberculosis or herpes simplex virus type 1 (HSV-1). This chemical also has been shown to have physiological effects on bowel disease and toxicity studies show that it does not cause any adverse reactions in rats or rabbits when given orally.

Azidopalmitic acid is a synthetic fatty acid that is used in the detection of cellular DNA. It can be detected using methods such as tritiated, expressed, or myristic azide. Azidopalmitic acid has also been shown to be compatible with polymerase chain reaction (PCR) and immobilized metal ion affinity chromatography (IMAC). This molecule is useful for conjugates that are radiolabeled with [3H]azidoacetyl palmitate and [14C]azidoacetyl palmitate. Azidopalmitic acid has been synthetically produced by reacting malonic acid with sodium azide. This compound is also reusable, which makes it an ideal way to label nucleotides during PCR reactions.

Palmitoyl-DL-carnitine chloride is a fatty acid that is an important component of cellular membranes. It has been shown to inhibit the growth of cancer cells in rats and mice by increasing the concentration of diacylglycerol in the cell membrane, which leads to increased formation of procyanidins. Palmitoyl-DL-carnitine chloride can also be used as an absorption enhancer for drugs and other compounds. The compound can be used to deliver drugs or other substances into cells, such as Caco-2 cells, for therapeutic purposes. Palmitoyl-DL-carnitine chloride has been shown to increase the production of ornithine in cultured mouse fibroblasts, which may be due to its ability to enhance cellular carnitine levels.

Paliperidone palmitate is a drug that is used in the treatment of schizophrenia. It is the most potent and selective atypical antipsychotic agent available. Paliperidone palmitate has shown long-term efficacy and low risk of extrapyramidal symptoms, which are associated with some other antipsychotic agents. The drug has been shown to have minimal effects on prolactin levels, although it can cause an increase in serum prolactin levels when administered with risperidone. Paliperidone palmitate is a prodrug that is metabolized by esterases to its active form, paliperidone. Paliperidone does not bind to plasma proteins and therefore may be more suitable for patients with hepatic impairment.

Applications Propargyl Alcohol is used as a corrosion inhibitor, a metal complex solution, a solvent stabilizer and an electroplating brightener additive. It is also used as an intermediate in organic synthesis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Zhang, T., et al.: Res. Chem. Interm. (2013); Choudhary, Y., et al.: SPE Product. Operat., 28, 268 (2013); Hed, Y., et al.: J. Mater. Chem. Mater. Bio. Med., 1, 6015 (2013);

Stability Light Sensitive, Temperature Sensitive
Applications rac 1-Oleoyl-2-linoleoylglycerol is a diacylglycerol from palm oil.
References Narvaez-Rivas, M., et al.: J. Agric. Food Chem., 55, 10953 (2007),

Applications 7-Bromo-1-ethyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester is an intermediate in the synthesis of Rosoxacin (R693580), an antibacterial agent used against Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Staphylococcus aureus and Streptococcus pneumoniae.
References Koba, M., et. al.: J. Mol. Modeling, 16, 327 (2010)

Applications (2E)-2-Hexadecenoic Acid Ethyl Ester (cas# 135251-95-5) is a compound useful in organic synthesis.

Stability 0-50C
Applications 4-(2,2-Dicarboethoxy-propyl)phenylacetic Acid Ethyl Ester (cas# 223123-63-5) is a compound useful in organic synthesis.

Applications (E)-2,2,3,5-Tetramethylhex-3-enoic Acid Ethyl Ester is an intermediate in the synthesis of 2,2,3,5-Tetramethylhexanoic Acid (T302890), a compound used in analytical studies as a method to quantitatively determine the total organic acid content in aqueous coolant.

Applications 2-Acetylbutanoic-d5 Acid Ethyl Ester (cas# 141327-44-8) is a compound useful in organic synthesis.

Applications Phenoxy-d5-acetic Acid Ethyl Ester (cas# 1189442-18-9) is a compound useful in organic synthesis.

Applications 5-(2,2,2-Trifluoroacetyl)-2-thiophenecarboxylic Acid Ethyl Ester is an intermediate in the synthesis of reagents for fluoroacetylthiophene oxadiazoles a class II human histone deacetylase inhibitors.
References Ontoria, J. M., et al.: J. Med. Chem., 52, 6782 (2009);

Applications Chlorosulfonyl acetic acid ethyl ester

Applications (4Z,6E)-4,6-Octadienoic Acid Ethyl Ester is an intermediate in the synthesis of Spilanthol (S681850), a fatty acid amide isolated from Acmella oleracea.
References Khadir, H., et al.: Pestic. Sci., 25, 329 (1989); Cech, N., et al.: Planta Med., 72, 1372 (2006); Saritha, K., et al.: Biol. Plant, 52, 334 (2008),

Applications 4-Bromo-2-chlorobenzeneacetic Acid Ethyl Ester (cas# 1261606-45-4) is a compound useful in organic synthesis.

Applications Intermediate in the preparation of Valproic acid metabolites
References Lee, R., et al.: J. Pharm. Sci., 78, 667 (1989),

Applications 3-(Acetylethylamino)-β-oxo-benzenepropanoic Acid Ethyl Ester is an intermediate used in the preparation of 5-Oxo-Zaleplon (O870470).

Applications 7-Bromo-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester is an intermediate in the synthesis of Rosoxacin (R693580), an antibacterial agent used against Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Staphylococcus aureus and Streptococcus pneumoniae.
References Koba, M., et. al.: J. Mol. Modeling, 16, 327 (2010)

Applications A 9-substituted derivative of the polycyclic aromatic hydrocarbon (PAH) Anthracene (A678400).

Applications A propargyl derivative used in the synthesis of substituted carbocyclic aromatic compounds and pharmaceutical compounds.
References Takahashi, H. et al.: J. Org. Chem., 74, 3632 (2009); Ding, F. & Jennings, M.: J. Org. Chem., 73, 5965 (2008)

Applications New lipids in food protein hydrolyzates. Fatty acid esters of chloropropanediol isolated from fresh goat milk.
References Velisek, J., et al.: J. Agric. Food Chem., 28, 1142 (1980), Myher, J.J., et al.: Lipids, 21, 309 (1986),

Applications 5-Hydroxy-2-oxo-2,3-dihydro-1H-[1]benzazephe-4-carboxylic Acid Ethyl Ester (cas# 108993-98-2) is a compound useful in organic synthesis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications 6,​7-​Dichloro-​1,​4-​dihydro-​4-​oxo-​3-​quinolinecarboxylic Acid Ethyl Ester is an intermediate in synthesizing 6-Chloro-6-defluoro Ciprofloxacin (C368035). It is an impurity of Ciprofloxacin (C482500), which is a fluorinated quinolone antibacterial.
References Hoffken, G., et al.: Antimicrob. Ag. Chemother., 27, 375 (1985), Scully, B.E., et al.: Lancet, 1, 819 (1986)

Applications 4-Phthalimidoacetoacetic Acid Ethyl Ester is an intermediate in the synthesis of 5-Aminolevulinic Acid-3-13C Hydrochloride which is a naturally occurring amino acid; precursor of tetrapyrroles in the biosynthesis of chlorophyll and heme. Antineoplastic (photosensitizer).
References Sisler, E.C., et al.: Physiol. Plant., 16, 315 (1963), Herdeis, C., et al.: Arch. Pharm., 317, 304 (1984), Peng, Q., et al.: Cancer, 79, 2282(1997),

Applications (1S,3R,4R)-3-[(tert-Butoxycarbonyl)amino]-4-[(methylsulfonyl)oxy]cyclohexanecarboxylic Acid Ethyl Ester is a starting material and useful building block of various pharmaceuticals.

Applications Can be used in the preparation of CCR5 antagonists, for treatment of HIV-1.
References Tallant, M. et al., Bioorg. Med. Chem. 21, 1394 (2011)

Applications 2-(Formylamino)-3-hydroxy-2-propenoic-13C2 Acid Ethyl Ester (cas# 1391062-48-8) is a compound useful in organic synthesis.

Applications (-)-(2S,3S)-Viridifloric Acid Ethyl Ester is an intermediate in the synthesis of (+)-amabiline, an unsaturated pyrrolizidine alkaloid from Cynoglossum amabile.
References Senter, T. J., et al.: Org. Lett., 14, 1869 (2012);

Applications 1-[(1E)-2-Nitroethenyl]-2-naphthalenol is an intermediate in the synthesis of 1-(2-Nitroethyl)-2-naphthol (N495895), an aromatic alcohol that is used in photoacid for extremely long lived and reversible pH jumps.
References Hu, K.L., et al.: Tetrahedron., 70, 181 (2014);

Applications 2-Bromo-2-propylpentanoic Acid Ethyl Ester (cas# 99174-91-1) is a compound useful in organic synthesis.

Applications (1E,5E)-1-Iodopentadeca-1,5-diene is an intermediate in the synthesis of (4E, 8E)-Sphingadienine-C18-1-phosphate (S680680), which is an analogue of (4E, 14Z)-Sphingadienine-C18 (S680630), a sphingoid base of sea cucumber cerebroside that may have cytotoxicity activity against human colon cancer cells.
References Sugawara, T., et. al.: Biosci. Biotech. Bioch., 70, 2906 (2006)

Applications 2-Amino-2-oxo-acetic Acid Ethyl Ester is a reagent used to prepare methanotetrahydroisoquinolinecarboxylic acid. It can also be used in preparation of 1,2,4-Thiadiazole, a Cathepsin B inhibitor.
References Czombos, J., et al.: J. Org. Chem., 65, 5469 (2000); Leung-Toung, R., et al.: Bioorgan. Med. Chem., 11, 5529 (2003)

1,16-Hexadecanediol is a plant hormone that is structurally related to abscisic acid and gibberellins. It is found in the tissues of plants. 1,16-Hexadecanediol has been shown to have the ability to regulate plant growth and development. The diffusional properties of this molecule suggest that it may be a model system for studying other molecules with similar properties. The conformational properties of this molecule are also important because they allow for hydrogen bonding, which stabilizes the molecule and prevents it from decomposing. This property also makes 1,16-hexadecanediol an excellent candidate as a low-energy sweetener. The molecule can be seen in nmr spectra as having two peaks at different chemical shifts because it contains intramolecular hydrogen bonds. The formula weight of 1,16-hexadecanediol is 270.27 g/mol.

Pimeloyl-CoA is a CoA derivative formed from pimelate, serving as a precursor in the biotin biosynthesis pathway of certain bacteria.

Applications Small unilamellar liposomes containing DOTMA interact spontaneously with DNA to form lipid-DNA complexes with 100% entrapment of DNA. Facilitates fusion of the complex with the plasma membrane of tissue culture cells, resulting in both uptake and expression of the DNA. Effective technique for transient and stable expression of transfected DNA.
References Zhu., N., et al.: Science, 261, 209 (1993), Wang, J., et al.: Pharmazie, 62, 723 (2007), Shur, J., et al.: J. Pharm. Sci., 97, 4857 (2008),

Applications rac-2-Linoleoyl-3-chloropropanediol, 95% (cas# 1470071-08-9) is a compound useful in organic synthesis.

Applications New lipids in food protein hydrolyzates.
References Velisek, J., et al.: J. Agric. Chem., 28, 1142 (1980),

Applications Methyl Propargyl Ether (cas# 627-41-8) is a useful research chemical.

Stability No Date Available
Applications (E)-4-Hydroxycrotonoic Acid Ethyl Ester is an intermediate in the preparation of unusual amino acids that are potential Michael acceptor based antiplasmodial and antitrypanosomal cysteine protease inhibitors.
References Breuning, A., et al.: J. Med. Chem., 53, 1951 (2010);