Flavonoides

<p>6-Methoxyflavonol is a flavonoid compound, which is a type of polyphenolic substance commonly found in various plants. It is derived from natural sources such as fruits, vegetables, and certain herbs. Flavonoids like 6-Methoxyflavonol are known for their diverse biological activities, largely attributed to their antioxidant properties. The compound acts as an antioxidant by neutralizing free radicals, which helps to protect cells from oxidative stress and potential damage.</p>

3-Hydroxy-7,3',4',5'-tetramethoxyflavone is a specific type of polymethoxylated flavonoid, which is a bioactive compound extracted primarily from the plant Oroxylum indicum. This compound falls into a broader class of flavonoids, which are polyphenolic compounds known for a variety of biological activities. The source, Oroxylum indicum, is a tree widely used in traditional medicine, particularly in Ayurveda, for its rich concentration of phytochemicals.

<p>Herbacetin is a naturally occurring flavonoid, which is a type of polyphenolic compound extracted from plants, particularly from the leaves of the flax plant. It functions primarily by inhibiting the activity of various enzymes and signaling pathways that are involved in oxidative stress and inflammatory responses. The inhibition of these pathways can modulate cellular processes, making it a subject of interest in the study of disease mechanisms and potential treatments.</p>

<p>Kaempferol 7-O-neohesperidoside is a flavonoid glycoside, which is commonly derived from various plant sources, including fruits, vegetables, and certain herbs. This compound is part of the broader flavonoid family, known for their bioactive properties, and can be extracted using advanced chromatographic techniques.</p>

<p>5,7,8-Trihydroxyflavone is a flavonoid compound, which is a type of phytochemical derived from the structural class of polyphenols commonly found in various plants. This specific flavonoid is naturally occurring in certain botanicals and can be isolated through extraction processes. The mode of action of 5,7,8-Trihydroxyflavone involves its interaction with cellular pathways, primarily acting as an antioxidant. It mitigates oxidative stress by scavenging free radicals and upregulating the expression of antioxidant enzymes.</p>

<p>7,2',4'-Trimethoxyisoflavone is a naturally occurring isoflavone, which is primarily found in certain plant species. As a derivative of the isoflavone family, it is sourced from botanical origins known for their rich content of phytoestrogens. The mode of action of 7,2',4'-Trimethoxyisoflavone is linked to its potential antioxidant properties, where it may interact with cellular mechanisms to mitigate oxidative stress by neutralizing free radicals.</p>

<p>3,3',4',5,7-Pentamethoxyflavone is a naturally occurring flavonoid compound, which is often extracted from specific plant sources. As a member of the flavonoid family, it is typically found in various plant extracts and contributes to the chemical diversity observed in phytochemistry.</p>

<p>Neohesperidin is a flavonoid-based natural sweetener, which is derived from the bitter orange and other citrus fruits. The mode of action of neohesperidin involves its conversion into neohesperidin dihydrochalcone (NHDC), which is an intensely sweet compound. This transformation occurs through hydrogenation, enhancing its sweetening properties. As a sweetener, NHDC exhibits around 1,500 to 1,800 times the sweetness of sucrose depending on the concentration and pH of the medium.</p>

Baicalein is a natural compound found in Scutellaria baicalensis, a medicinal plant used in the Chinese traditional medicine. Baicalein has anti-tumoral properties as it was shown to interact with several molecular targets involved in tumour biology, such as Erk, ROS, MMP-2/-9, p53 and MAPK. Baicalein was also reported as a non-covalent, non-peptidomimetic inhibitors of the main protease Mpro (3CLpro) from SARS-CoV-2 with IC50 of 0.94 μM and EC50 of 1.69 μM.

<p>Rhamnetin 3-rhamnoside is a flavonoid glycoside, which is a type of polyphenolic compound typically found in plants. It is primarily derived from natural sources such as fruits, vegetables, and certain medicinal plants, where it often contributes to the plant's natural defense mechanisms. The compound acts as a potent antioxidant due to its capability to scavenge free radicals, thereby protecting cells from oxidative stress and potential damage.</p>

5,3',4'-Trihydroxyflavone is a natural flavonoid compound often found in a variety of plants. This compound is derived from numerous botanical sources, including fruits and vegetables known to contain flavonoids, which are secondary metabolites widely distributed in the plant kingdom. The mode of action of 5,3',4'-Trihydroxyflavone involves its ability to interact with diverse biological pathways, often exhibiting antioxidant, anti-inflammatory, and potential anti-cancer effects. This interaction occurs through the modulation of enzyme activity and signaling pathways, as well as the scavenging of free radicals, thereby protecting cells from oxidative stress and damage.

<p>Amentoflavone is a biflavonoid compound, which is a naturally occurring substance found in various plants such as Ginkgo biloba and Hypericum perforatum. Its molecular structure consists of two flavonoid units joined together, contributing to its unique biochemical characteristics. The source of amentoflavone spans across several medicinal plants, where it plays roles in the plants’ defense mechanisms.</p>

Diosmetin is a flavonoid compound, which is derived from natural sources such as citrus fruits and certain herbs. As an aglycone of the flavonoid glycoside diosmin, it is primarily sourced through the metabolic transformation of diosmin in the body. Diosmetin functions through modulation of oxidative stress pathways and inhibition of pro-inflammatory enzymes. Its biochemical activity includes scavenging free radicals and reducing the activity of certain inflammatory mediators, which contributes to its potential therapeutic effects.

<p>Pratol is a synthetic antiparasitic agent, which is chemically synthesized from readily available organic precursors. It functions by disrupting the vital metabolic pathways of the targeted parasites, specifically inhibiting certain enzymes vital for parasite survival. Pratol's mode of action involves binding to the active site of these enzymes, effectively halting the necessary biochemical transformations and leading to the death of the parasite.</p>

<p>6-Hydroxygenistein is a phytoestrogen, which is derived from soy-based isoflavones. Its source, primarily found in soybeans, is rich in naturally occurring compounds that exhibit estrogen-like activity. 6-Hydroxygenistein operates through various mechanisms, including acting as an antioxidant and interacting with estrogen receptors to modulate biological processes.</p>

<p>Cannflavin B is a specialized flavonoid compound, which is a secondary metabolite derived from Cannabis sativa. It exhibits a distinct mode of action as a potent anti-inflammatory agent. Cannflavin B exerts its effects through the inhibition of pro-inflammatory mediators such as prostaglandins and leukotrienes. These biochemical pathways are typically linked with the cyclooxygenase (COX) and lipoxygenase (LOX) enzymes, and Cannflavin B effectively interferes with these enzymatic processes to reduce inflammation at the molecular level.</p>

7,3',4',5'-Tetramethoxyflavanone is a flavanone derivative, which is a type of polyphenolic compound. These compounds are prevalent in various plant sources, particularly in citrus fruits and other flavonoid-rich botanicals. Flavanones, such as this compound, are synthesized through the methylation of hydroxy flavanones, which alters their solubility and bioactivity profiles.

Daidzein 7,4'-di-O-glucoside is a naturally occurring isoflavone glycoside, which is a type of phytochemical commonly found in soybeans and other legumes. It derives from the plant family Fabaceae and is a derivative of daidzein, conjugated with glucose units. Isoflavones like daidzein 7,4'-di-O-glucoside are known for their potential estrogenic and antioxidant activities due to their structural similarity to estradiol, an estrogen hormone.

<p>7,2'-Dibenzyloxy-4',5'-methylenedioxyisoflavone is a synthetic compound derived from isoflavones, a class of naturally occurring organic compounds related to flavonoids. Isoflavones are typically found in plants, especially in legumes, and are known for their diverse biological activities. This particular derivative has been designed to explore advanced pharmacological properties through structural modification aimed at improving bioactivity and specificity.</p>

<p>3-Hydroxy-7,3'-dimethoxyflavone is a naturally occurring flavonoid, which is a subclass of polyphenolic compounds found in various plants. As a flavonoid, it is characterized by its polyphenolic structure and the presence of hydroxyl and methoxy groups, which are integral to its biological activity. Originating from diverse plant sources, these compounds are often isolated for their potential health benefits and biological activities.</p>

Quercetagetin is a flavonoid compound, which is naturally sourced from the marigold plant, *Tagetes* species. This flavonoid is structurally related to other polyphenols and is synthesized in plants through the phenylpropanoid pathway. Quercetagetin primarily exerts its biological effects through the scavenging of reactive oxygen species (ROS) and modulating various signaling pathways associated with oxidative stress.

<p>6-O-Acetyldaidzin is a chemical compound that serves as an isoflavone derivative, primarily obtained from the acetylation of daidzin. This compound is a naturally occurring glycoside found in soy products and other leguminous plants, acting as a bioactive constituent with diverse pharmacological properties.</p>

<p>5-Hydroxy-3',4'-dimethoxyflavone is a naturally occurring flavone, which is a type of polyphenolic compound found in various plants. It is derived from plant sources, specifically from certain species that are known for their rich phenolic content. The mode of action of this compound involves antioxidant activity, where it scavenges free radicals and reduces oxidative stress, which may contribute to its health-related properties.</p>

<p>7,2'-Dimethoxyflavone is a naturally occurring flavone compound, which is a type of phytochemical widely distributed in the plant kingdom. It is derived from various plant sources, particularly within species known for traditional medicinal uses. The compound exhibits multiple modes of action, primarily interacting with cellular pathways related to oxidative stress and enzyme modulation. It acts as an inhibitor of specific enzymatic processes, contributing to its potential therapeutic effects.</p>

7,2',4'-Tribenzyloxy-8-methoxyisoflavone is a synthetic isoflavone derivative, which is structurally modified for research purposes. It is typically derived from chemical manipulation of naturally occurring flavonoid compounds found in various plants. The compound is noted for its ability to modulate biochemical pathways due to its interaction with estrogen receptors and other cellular targets. This mode of action makes it particularly useful in the study of estrogenic activities and their implications in various biological processes.

<p>2'-Benzyloxy-7,4'-dimethoxyisoflavone is a synthetic isoflavone, which is primarily derived from the benzyl ether of naturally occurring flavones. Isoflavones are typically sourced from plants, such as soybeans, and are known for their estrogenic activity and various biological effects. The modification to produce 2'-Benzyloxy-7,4'-dimethoxyisoflavone involves chemical synthesis that retains the core isoflavone structure while introducing specific substituents to enhance its biological properties.</p>

<p>7,3-Dihydroxyflavone is a potent small-molecule flavonoid, which is a naturally occurring compound sourced primarily from plants. This compound functions as a selective agonist for the TrkB receptor, which is the high-affinity receptor for brain-derived neurotrophic factor (BDNF). By mimicking BDNF, 7,3-Dihydroxyflavone activates intracellular signaling pathways that are crucial for neuronal survival, differentiation, and synaptic plasticity.</p>

<p>Gossypetin-7-glucoside is a flavonoid glycoside, which is a naturally occurring compound found primarily in plants. This substance is derived from the flavonoid gossypetin, which is a member of the flavonoid class of polyphenolic secondary metabolites in plants, predominantly sourced from cotton plants. The mode of action of gossypetin-7-glucoside is largely attributed to its antioxidant properties. It acts by scavenging free radicals, thereby reducing oxidative stress and potentially mitigating cellular damage.</p>

<p>Isorhamnetin is a naturally occurring flavonoid, which is isolated from various plant sources such as fruits, vegetables, and medicinal herbs like Ginkgo biloba. As a member of the flavonoid family, it is primarily derived from the glycosylation and methylation of quercetin. The mode of action of isorhamnetin is mainly attributed to its potent antioxidant capabilities. It scavenges reactive oxygen species and inhibits oxidative stress, which may lead to beneficial effects in preventing cellular damage.</p>

Anti-peroxidative; anti-inflammatory; anti-proliferative; induces apoptosis

<p>Pinocembrin is a flavonoid compound, which is a type of polyphenolic molecule, extracted primarily from honey, propolis, and various plants. It is characterized by its unique structure allowing it to function effectively as an antioxidant. The mode of action of Pinocembrin involves scavenging free radicals and reducing oxidative stress, which contributes to its protective effects on cells and tissues.</p>

7,3'-Dimethoxy-3-methylflavone is a synthetic flavonoid compound, which is based on the structural class of flavones known for their diverse biological activities. Flavonoids are primarily found in plants, where they contribute to pigmentation, UV filtration, symbiotic nitrogen fixation, and plant growth regulation. This particular compound, however, is synthesized in laboratory settings to replicate and modify these natural attributes for specific research purposes.

Conrauinone A is a naturally derived compound, which is a specialized natural product extracted from a specific plant source. This compound is known for its unique structural properties and potential biological activities. Conrauinone A functions primarily through a mode of action that involves interaction with specific cellular targets, leading to modulation of biochemical pathways that are crucial for certain cellular processes.

<p>7,8-Dihydroxyisoflavone is an isoflavone compound, which is a naturally derived product found predominantly in plants like Trifolium pratense, also known as red clover. It is classified as a selective tyrosine receptor kinase B (TrkB) agonist, which means it can mimic the action of brain-derived neurotrophic factor (BDNF), a protein crucial for neuronal survival, growth, and differentiation in the central nervous system.</p>

<p>Eucomol is a synthetic compound derived from plant-based sources, designed as an antioxidant agent. It functions by scavenging reactive oxygen species (ROS), thereby reducing oxidative stress in biological systems. Eucomol's mode of action involves donating electrons to neutralize free radicals, which prevents cellular damage and maintains cellular homeostasis.</p>

Hinokiflavone-7,7”,4”’-trimethyl ether is a specialized biflavonoid compound, which is a type of plant secondary metabolite. Derived primarily from certain species of the Cupressaceae family, it showcases the diverse capabilities of flavonoids in biochemical pathways. This compound functions by modulating enzyme activities, interacting with cellular receptors, and exhibiting antioxidant properties. It acts through mechanisms involving inhibition of specific kinases and other enzymes, thereby influencing cell signaling pathways and inflammatory responses.

<p>6,7-Dimethoxy-3',4',5-trihydroxyflavone is a specialized flavonoid compound, which is commonly isolated from plant sources known for their rich polyphenolic content. These compounds are typically synthesized by plants as secondary metabolites, playing critical roles in plant defense and pigmentation. The mode of action of 6,7-Dimethoxy-3',4',5-trihydroxyflavone primarily involves its potent antioxidant activity, where it effectively scavenges free radicals and inhibits oxidative stress at the cellular level. This antioxidant property is attributed to its ability to donate hydrogen atoms or electrons, thereby neutralizing potentially damaging reactive oxygen species (ROS).</p>

<p>5,7,4'-Trimethoxyisoflavone is a naturally occurring isoflavone compound, which is a type of phytochemical typically extracted from various plant sources, including legumes and certain medicinal herbs. Isoflavones are a class of phytoestrogens – plant-derived compounds with estrogenic activity – found predominantly in soy products.</p>

<p>Ficifolinol is a bioactive compound, which is a naturally occurring phenolic compound derived from the plant genus *Eucalyptus*, particularly from the species known for their rich bioactive profiles. Ficifolinol acts primarily through its antioxidant mechanisms, scavenging free radicals and inhibiting oxidative stress, thereby contributing to cellular protection and stability.</p>

<p>Agathisflavone-7,7”-dimethyl ether is a methylated flavonoid, a type of natural compound belonging to the biflavonoid family. This compound is primarily derived from plant sources, particularly from the leaves and seeds of certain leguminous plants. It presents unique biochemical properties due to the dimethyl ether groups attached to its flavonoid structure.</p>

<p>Eriodictyol-7-neohesperidoside is a flavonoid glycoside, a type of compound that naturally occurs in certain plant species, notably within the genus Eriodictyon. This compound is a derivative of eriodictyol, which is found widely in citrus fruits. Its mode of action is primarily linked to its ability to interact with taste receptors, making it notable for its potential to modulate taste perceptions, specifically in the context of bitterness. This makes it of significant interest in the field of food science and technology.</p>

3-Hydroxy-6,3',4',5'-tetramethoxyflavone is a naturally occurring flavonoid, which is derived from various plant sources, including certain species of the genus Chromolaena. It belongs to a class of polyphenolic compounds known for their potential biological activities. This flavonoid acts primarily through antioxidant mechanisms, where it scavenges free radicals and inhibits oxidative stress pathways. Additionally, it can modulate various signaling pathways, implicating roles in anti-inflammatory processes and cellular protection.

Swertiajaponin is a natural bioactive compound, classified as a flavonoid glycoside, which is derived from the plant Swertia japonica. Swertia japonica, a member of the Gentianaceae family, is predominantly found in East Asia, where it has been traditionally used in herbal medicine. As with many bioactive compounds, swertiajaponin exhibits its pharmacological effects through various biochemical interactions, including antioxidant, anti-inflammatory, and hepatoprotective activities. It is known to modulate cellular pathways and free radical scavenging, contributing to its therapeutic potential.

<p>3-Hydroxy-6,2',4'-trimethoxyflavone is a naturally occurring flavonoid derivative, which is a type of secondary metabolite primarily found in various plant species. This compound is derived from the flavonoid family, known for their diverse biological activities and health-related benefits. The mode of action of 3-Hydroxy-6,2',4'-trimethoxyflavone involves its interaction with molecular pathways associated with antioxidant, anti-inflammatory, and potentially anti-cancer activities. It is thought to modulate signaling pathways that play crucial roles in cellular homeostasis, making it a compound of interest in pharmacological research.</p>

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Quercetin 3-O-xyloside is a flavonoid glycoside, which is typically isolated from various plant sources, such as fruits, vegetables, and herbs. This compound is characterized by the presence of a quercetin molecule attached to a xylose sugar moiety, influencing its solubility and biological activity.

<p>7-Hydroxy-2',4',5'-trimethoxyisoflavone is a naturally occurring flavonoid, which is commonly isolated from various plant sources, including legumes and other flavonoid-rich botanical species. This compound exhibits a unique structural configuration characterized by hydroxyl and methoxy functional groups, contributing to its notable bioactivity.</p>

Isoliquiritin is a bioactive compound, specifically a flavonoid, which is derived from the roots of Glycyrrhiza glabra, commonly known as licorice. It possesses diverse pharmacological properties with multiple modes of action, notably influencing pathways involved in oxidative stress and inflammation. Isoliquiritin acts as an antioxidant, scavenging free radicals and reducing oxidative damage at the cellular level. Additionally, it exhibits anti-inflammatory effects by modulating the expression of inflammatory cytokines and inhibiting specific signaling pathways like NF-κB.

<p>3,5,7,8,3',4'-Hexahydroxyflavone is a specialized flavonoid, which is a type of polyphenolic compound found naturally in plants. This compound is derived from various botanical sources, particularly in leaves and peels where flavonoids are abundant. The presence of multiple hydroxyl groups contributes to its potent antioxidant activity, allowing it to scavenge free radicals effectively.</p>

<p>Scutellarein 7-O-rutinoside is a flavonoid glycoside, which is a type of organic compound found predominantly in various plant species. This compound is mainly extracted from plants such as Scutellaria and Verbena, known for their rich flavonoid content. Its mode of action involves modulating various cellular pathways due to its antioxidant properties, which can scavenge free radicals and reduce oxidative stress in biological systems.</p>